43results about How to "Convenient purification work" patented technology

The invention discloses to a lycopene emulsion capable of stably reducing gas-phase free radicals of cigarettes and a user thereof, belonging to the technical field of cigarettes. The lycopene emulsion of the invention is prepared by the following steps: [1], extracting the lycopene; and [2], preparing the lycopene emulsion, wherein the emulsion is one of sucrose fatty acid ester, glycerin monostearate, sorbitantristearate or polyoxyethylene sorbitan fatty acid ester (tween) or a mixture of any several substances. The assistant is one of propylene glycol, glycerine, ethylene glycol and ethanol or a mixture of any several substances. In the use of the lycopene emulsion capable of stably reducing gas-phase free radicals of cigarettes in cigarettes, the lycopene emulsion is independently matched with tobacco flavors for charging the tobacco leaves or flavoring the tobacco shreds. The lycopene emulsion disclosed by the invention is stable for at least 6 months. The cigarette with the lycopene emulsion is capable of effectively reducing the gas-phase free radicals of cigarettes by over 17%.

The invention provides a method for preparing a gonadotropin-releasing hormone (GnRH) parallel body and a vaccine in solid-phase conditions. After Lys is coupled on carrier resin, rink amide liners are respectively coupled on the two side chains of the Lys, and two same peptide chains are synthesized simultaneously. Disulfide bond bridging is realized on a solid phase, full-protective oxidation is adopted, and a large amount of impurities caused by the reaction involved by the side chains in the process are avoided.

The invention is a long-acting exenatide derivative, which belongs to the technical field of polypeptide compounds. The exenatide derivative is structurally optimized for the exenatide sequence, so that it has hypoglycemic and weight-reducing effects at the same time, and double the amount of exenatide is conjugated with a single amount of fatty acid chains. The fatty acid chain plays a binding role with serum albumin to obtain exenatide derivatives with longer pharmacological action time. The invention also discloses a preparation method of exenatide derivatives, a pharmaceutically acceptable salt of exenatide derivatives, a pharmaceutical composition of exenatide derivatives, a pharmaceutical composition and a use thereof. Application of the derivative in the preparation of medicines for treating and / or preventing diabetes, obesity, hyperlipidemia and non-alcoholic fatty liver. The long-acting exenatide derivatives can reduce the weight on the basis of retaining the hypoglycemic activity, and the biological half-life is significantly longer than that of the exenatide prototype, and some of them have reached more than 36 hours, which greatly prolongs the hypoglycemic effect. Time of bariatric action.