32 results about "Piperlongumine" patented technology

The invention discloses a piperlongumine derivative as well as a preparation method and application thereof, and belongs to the technical field of medical chemistry. The piperlongumine derivative isshown as a formula (I): the piperlongumine derivative, as well as any mixture of these forms or a pharmaceutically acceptable salt thereof, can be used as the target Keap1 molecular probe, can position and bind the Keap1 protein in a lysis solution, and can be detected in the Western-Blot at the later stage so as to provide the new means for the research of the anti-tumor effect mechanism of the piperlongumine. According to the method, 3-hydroxy-4-nitrobenzaldehyde is used as a raw material, the synthesis process is simple, efficient and rapid, and the prepared piperlongumine derivative has relatively high yield.

The invention discloses application of piperlongumine in a herbicide for preventing and controlling an agricultural weed. The herbicide is used for preventing and controlling the agricultural weed. The active ingredient of the herbicide is piperlongumine with a concentration of 1-10 mg/mL. The agricultural weed is one or more than one selected from the group consisting of barnyard grass, sudangrass, abutilon fiber, edible amaranth, moleplant seed, amaranthus retroflexus, echinochloa oryzoides, eleusine indica, digitaria sanguinalis and spermacoce latifolia. The piperlongumine has a remarkable inhibition effect on the agricultural weed, and a natural-source herbicidal active substance is provided for prevention and control of the agricultural weed; piperlongumine can be used for preventing and treating various important agricultural weeds such as digitaria sanguinalis, abutilon fiber, barnyard grass and amaranthus retroflexus; and the characteristics of high efficiency, low toxicity, safety and the like of piperlongumine serving as a herbicide meet the requirements of creation and development of current novel pesticides.