188 results about "Acylal" patented technology

The present invention provides a cellulose ester composition, containing 1 to 99% by weight of cellulose triacetate prepared by substituting hydroxyl groups of cellulose with acetyl and having a degree of substitution with acetyl, DSace, which satisfies the relationship: 2.7</=DSace</=3.0, and 99 to 1% by weight of a mixed fatty acid ester of cellulose prepared by substituting hydroxyl groups of cellulose with acetyl and acyl groups having three or more carbon atoms and having degrees of substitution with acetyl and acyl groups having three or more carbon atoms, DSace and DSacyl, respectively, which satisfy the relationships: (I) 2.20</=DSace</=2.95, (II) 0.05</=DSacyl</=0.80 and (III) 2.60</=DSace+DSacyl</=3.00.

Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.

The invention relates to comb polymers which comprise, in the main chain, repeating units which are derived from polyolefin-based macromonomers, and repeating units which are derived from low molecular monomers which are selected from the group consisting of styrene monomers having 8 - 17 carbon atoms, alkyl(meth)acrylates having 1 - 10 carbon atoms in the alcohol group, vinyl esters having 1 - 11 carbon atoms in the acyl group, vinyl ethers having 1 - 10 carbon atoms in the alcohol group, (Di)alkylfumarates having 1 - 10 carbon atoms in the alcohol group, (Di)alkylmaleates having 1 - 10 carbon atoms in the alcohol group and mixtures of said monomers. The molar branching degree lies in the region between 0.1 - 10 mol. % and the comb polymer represents the sum of at least 80 wt. %, in relation to the weight of the repeating units, on repeating units which are derived from polyolefin-based macromonomers, and repeating units which are selected from low molecular monomers which are selected from the group consisting of styrene monomers having 8 - 17 carbon atoms, alkyl(meth)acrylates having 1 - 10 carbon atoms in the alcohol group, vinyl esters having 1 - 11 carbon atoms in the acyl group, vinyl ethers having 1 - 10 carbon atoms in the alcohol group, (Di)alkylfumarates having 1 - 10 carbon atoms in the alcohol group, (Di)alkylmaleates having 1 - 10 carbon atoms in the alcohol group, and mixtures of said monomers.

A method for producing a diacylglycerol-rich fat or oil is provided. This method includes the steps of reacting an acyl group donor with an acyl group receptor, and separating unreacted material and byproducts by distillation for use as a part of the starting material in the subsequent cycle of production. The distillation is conducted such that the content of monoacylglycerol in the fat or oil after the distillation is 0.5 to 15% by weight.

The present invention relates to a starch ester having short- and long-chain acyl groups wherein hydrogens in reactive hydroxyl groups in the same starch molecule have been replaced by C2-4 short-chain acyl groups and C6-18 long-chain acyl groups. The degree of substitution by the short- and long-chain acyl groups are regulated so as to make the starch ester thermo-plasticized and moldable even in the absence of a plasticizer. Accordingly, the starch ester of the present invention can be used as a biodegradable thermoplastic plastic material which can be thermo-plasticized in the absence of a plasticizer.

Anhydrous cosmetic antiperspirant stick compositions containing a continuous phase of a water-immiscible cosmetic oil structured by a fibre-forming amido structurant can exhibit undesirable sensory properties when 12-hydroxy-stearic acid is employed as primary gellant and the preparation of sick compositions suffers from sever processing difficulties when certain of such amido structurants are employed as primary gellant. Stick compositions having desirable sensory properties can be made by employing as primary gellant, a combination of amido structurants comprising (i) an N-acylaminoacid amide in which the N-acyl substituent has the formula -CO-R<X >in which R<X >represents a branched C6 to C11 alkyl group and (ii) an N-acylaminoacid amide in which the N-acyl substituent contains a linear alkyl group and the cosmetic carrier oil comprising from 25 to 50% by weight of a water-immiscible monohydric alcohol that is liquid at 20° C. and a boiling point of higher than 100° C.

The invention discloses acyl-substituted triptycene and a preparation method thereof. An acyl compound is represented as structural general formula I or II. A framework of the compound is triptycene with a rigid three-dimensional structure. Two or three acyls are selectively introduced on the triptycene framework and can conveniently polymerized into a polymer through McMurry reaction, and the structure of the produced polymer is represented as general formula VI or VII. The preparation method of the acyl-triptycene derivative has the advantages of being cheap in raw materials, simple in synthetization, high in productivity, easy to derivatize and the like. In addition, the produced polymer has good dissolubility, and the acyl-substituted triptycene can be processed conveniently and has wide application prospect.

The invention provides a method for synthesizing (E)-(2-(phenylsulfonyl)vinyl)benzene and a derivative thereof. The method adopts styrene or a derivative of styrene as a reactant A and sodium benzenesulfinate or a derivative of sodium benzenesulfinate as a reactant B, and the reactant A and the reactant B react under the oxidation of persulphate to generate (E)-(2-(acyl)vinyl)benzene and the derivative thereof. Compared with the conventional method utilizing thioether oxidation, sulfur dioxide addition, Friedel-Crafts sulfonylation and transition metal catalysis coupling, the method increasesyield, and since the method utilizes relatively cheap persulphate as oxidant to carry out reaction, the cost of synthesis is reduced.

The present invention provides 3-substituted amino-1, 2, 4-substituted phentriazine-1, 4-dioxides in the general expression as shown. The compounds are prepared with substituted one-nitroaniline as main material and through acylation to produce urea, cyclization, chlorination, amino substitution, oxidation and other steps. The tests show that the compounds of the present invention have anticancer activity and hypoxia selectivity higher than those of TPZ and may be used in preparing hypoxia selective anticancer medicine.

The invention discloses a polyether amine and a preparation method thereof, and belongs to the technical field of high polymer material synthesis and preparation. According to the polyether amine and the preparation method thereof, a ketone, an aldehyde or an acid anhydride is reacted with primary amine for the first time to generate ketimine, aldimine or acyl protected amine compounds, and secondary amine or active hydroxyl and an alkylene oxide monomer are subjected to anionic polymerization so as to successfully synthesize polyether amine containing primary amine. The defects that the conventional method, namely, direct hydroxyl amination, requires harsh conditions of the equipment and the process, and side reaction is likely to happen when the amine compound is bonded with a polyether chain, are overcome, and polyether amine which is moderate in reaction condition and tidy in structure is successfully synthesized. The polyether amine has potential application in the fields of machine manufacturing, electrical equipment and electronic devices, communication and transportation, petrochemical engineering, national defense construction, electrophoretic paint, anticorrosive paint and the like.

The invention belongs to the fields of biological catalysis and biotransformation and discloses a method for preparing an esterified derivative of lily polysaccharide by biological catalysis. The method comprises the following steps of catalyzing lily polysaccharide by utilizing lipase for transesterification reaction at the temperature of 35-55 DEG C based on an ionic liquid as a solvent and vinyl ester fatty acid with C2-C18 carbon chain length as an acyl group donor and synthesizing to obtain the esterified derivative of lily polysaccharide. The method has the advantages that reaction condition is moderate and environment-friendly, the reaction is controllable and simple in process, the product is easy to separate from a reaction mixing system, and the like.

The cross-linked hydrosilylation reaction product of an alkenyl functional silicone compound, a silylhydride functional silicone compound, and one or more allyl started, hydrogen, alkyl, aryl or acyl terminated polyether compounds exhibits stability, compatibility with polar organic solvents and is useful as a component in personal care compositions.

The invention discloses a new method for preparing cytidine. The method adopts the acyl-protected carbohydrate and acyl-protected cytosine as reactants and the acid or meta-acid ionic liquid as a catalyst, and comprises the following steps of: reacting at a temperature of (-5)-55 DEG C in a solvent for 5-20 hours to obtain a corresponding acyl-protected cytidine derivative; and saponifying to remove the protecting group to obtain cytidine. The new method disclosed by the invention has the advantages that: the catalyst has a wide source and is easily available; and the reaction conditions are mild, the operation is convenient, the yield is relatively high, the pollution is little, and the method can be applied to large-scale production.

The invention discloses a new method of preparing vilazodone intermediate 5-piperazin-2-acyl substituted benzofuran. The method comprises a coupling reaction of 5-halogen substituted 2-acyl substituted benzofuran (III) and piperazine compound (IV) in the presence of a metal palladium catalyst, a ligand, a solvent and a base to obtain the 5-piperazin-2-acyl substituted benzofuran. The method has advantages of short route, convenient synthesis and high yield, and is suitable for industrial production.

The invention discloses a method for synthesizing an acrylamide derivative as shown in the synthesis formula (I). The acrylamide derivative is obtained by performing reductive acylation and isomerization on an oxime derivative and an acyl compound in the presence of a Pd, Cu or Ni transition metal catalyst and a proper reducing agent, wherein R1, R2 and R3 independently are hydrogen atoms, aryl, aryloxy, alkyl, cyclalkyl, alkoxy, heterocyclyl, carboxyl, esteryl, cyano, sulfonyl and carbamoyl; or R1 and R2 are combined into ring; or R2 and R3 are combined into a ring; R4 is hydrogen atom, alkyl or aryl; n is 1 or 2; and when n is 1, X is a leaving group and when n is 2, X is an oxygen atom. A series of high-yield substituted acrylamide compounds can be obtained under a mild condition by reducing and acylating oxime in the presence of the transition metal catalyst. The method has the characteristics of mild reaction condition, simple operation, wide application range, low production cost, high synthesis yield and the like.