The invention discloses a synthesis method of N-methyl-1,2-benzenediamine dihydrochloride. The synthesis method is characterized by comprising the following steps that 1, o-
chloronitrobenzene and a monomethylamine
aqueous solution are subjected to a sealing reaction, after the reaction is completed, cooling, standing and layering are conducted, and a lower-layer
oil phase is collected to obtain N-methyl-2-
nitroaniline; 2, a catalyst is added to a
mixed solution of ethyl
alcohol and the N-methyl-2-
nitroaniline obtained in step 1, after mixing and heating, hydrazine
hydrate is slowly dropwise added to the
mixed solution, and after drop addition is completed, a heat preservation reaction is conducted; after the reaction is completed, suction
filtration is conducted, and a suction
filtration mother solution is reserved to obtain N-methyl-o-phenylenediamine; 3, liquid caustic soda, water and EDTA are added to the N-methyl-o-phenylenediamine obtained in step 2 for mixing, after cooling is conducted,
dichloromethane is added, stirring, extraction, standing and layering are conducted, a lower-layer
oil phase is collected, and through separation and purification, the target product N-methyl-1,2-benzenediamine dihydrochloride is obtained. The N-methyl-1,2-benzenediamine dihydrochloride product prepared through the method has high purity and few impurities and can be widely applied to the field of intermediate synthesis of a
medicine tishamitan for reducing the
blood pressure.