63 results about "Endovascular therapy" patented technology

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, engaging an interventional device of a catheter system with clot material in a blood vessel and withdrawing the interventional device and the portion of the clot material through a guide catheter. In some embodiments, the catheter system can include an attachment / valve member coupled to a proximal portion of the guide catheter, and the method can include unsealing the attachment / valve member to facilitate withdrawing the interventional device through the attachment / valve member without significant retention of clot material within the attachment / valve member. The method can further include resealing and aspirating the guide catheter before advancing another interventional device to the clot material to again engage and remove clot material from the blood vessel.

A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, engaging an interventional device of a catheter system with clot material in a blood vessel and withdrawing the interventional device and the portion of the clot material through a guide catheter. In some embodiments, the catheter system can include an attachment / valve member coupled to a proximal portion of the guide catheter, and the method can include unsealing the attachment / valve member to facilitate withdrawing the interventional device through the attachment / valve member without significant retention of clot material within the attachment / valve member. The method can further include resealing and aspirating the guide catheter before advancing another interventional device to the clot material to again engage and remove clot material from the blood vessel.

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A device in accordance with embodiments of the present technology can include, for example, a plurality of interconnected struts forming a unitary structure having a proximal portion and a distal portion. The struts can form a plurality of first cells in the proximal portion and a plurality of second cells, smaller than the first cells, in the distal portion. The device can be pulled against clot material within a blood vessel to engage, disrupt, and / or capture the clot material.

An intravascular therapy guidance system includes a processor circuit in communication with an extravascular imaging device. The processor circuit receives, from the extravascular imaging device, an extravascular image stream. The processor circuit determines a therapy region of a blood vessel in the extravascular image stream and outputs a screen display to a display in communication with processor circuit. The screen display includes the extravascular image stream of the blood vessel including movement of an intravascular therapy device within the blood vessel to deliver an intravascular therapy to the therapy region and a graphical representation of the therapy region overlaid on the extravascular image stream. The processor circuit determines, based on the extravascular image stream, whether the intravascular therapy device is aligned relative to the therapy region to deliver the intravascular therapy and modifies the screen display to indicate whether the intravascular therapy device is aligned to deliver the intravascular therapy.

Disclosed herein are systems and methods for endovascular treatment of clot material within a blood vessel of a human patient. In one embodiment, a system includes a coring element for coring and separating the clot material. The coring element may include a single structure having a first region, a second region, a third region, and a fourth region. The first region is adjacent to a proximal portion of the unitary structure and includes a first mouth configured to core and separate the clot material. The second region is distal to the first region, is substantially tubular, and includes a first plurality of interconnected struts. The third region is distal to the second region and includes a second mouth configured to core and separate a vascular thrombus. The fourth region is distal to the third region, is substantially tubular, and includes a second plurality of interconnected struts.

The present disclosure relates to systems and methods for intravascular treatment of intravascular clots in a human patient. A method according to an embodiment of the present technology may include, for example, positioning a distal portion of a catheter near an intravascular clot. The method may further include coupling a pressure source to the catheter via a conduit subsystem that includes a valve or other fluid control device, and activating the pressure source to charge a vacuum while the valve is closed. The valve may then be opened to apply the vacuum to the catheter, thereby sucking at least a portion of the clot into the catheter from the blood vessel.

An endovascular therapy system includes an endovascular device. The endovascular device includes an elongated body configured to be introduced into vasculature of a patient. The endovascular device includes a coil structure at a distal portion of the elongated body. The coil structure includes at least a first coil portion and a second coil portion. The first coil portion can be configured to carry a plurality of electrodes. The second coil portion can be formed from a coiled wire such that the second coil portion together with the coiled wire defines a coiled coil. The coiled wire can extend distally of a distal end of the first coil portion and be configured to anchor the elongated body and the coil structure within the vasculature of the patient.

Systems and methods for removal of clot material from vessel lumens are disclosed. A thrombectomy system can include a tubular member having a proximal end region configured to be disposed extracorporeally and a distal end region configured to be disposed at an intravascular treatment site at or adjacent to a thrombus. The tubular member has a sidewall defining a lumen extending therethrough from the proximal end region to the distal end region. The sidewall has an opening in the distal end region, the opening including a proximal portion spanning a first width and a distal portion spanning a second width greater than the first width. The thrombectomy system can additionally include a suction source configured to be fluidically coupled to the lumen.

The invention relates to a dilator (10) for intravascular treatment, which can be moved in a catheter and has a proximal longitudinal end (11), a distal longitudinal end (12), which is tapered in the distal direction, and a shaft (13), wherein the dilator (10) has an inner lumen (14) for receiving a guide wire (20), which opens into a proximal outlet opening (15) and a distal outlet opening (16) for the guide wire (20), wherein the distal outlet opening (16) is arranged at the distal longitudinal end (12) of the dilator (10), characterised in that the proximal outlet opening (15) is arranged on a proximal section (13a) of the dilator (10), in that the guide wire (20) passes intracorporeally through the proximal outlet opening (15), wherein a transport wire (30) is connected to the proximal longitudinal end (11) of the dilator (10) such that the dilator (10) can be moved in the catheter by the transport wire (30).

Embodiments of catheters, methods, and devices for endovascular treatment of a blood vessel uses a catheter. The catheter includes a catheter body including a distal end and a distal tip assembly (100) movably connected to the catheter body at the distal end of the catheter body. The distal tip assembly includes a plurality of tips (102. 104. 106) that nest together and of which each comprises a fistula forming element and a support shaft. At least one of the plurality of tips is independently movable relative to an adjacent one of the plurality of tips between a retracted position and an extended position to provide a treatment region therebetween. WO

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, engaging an interventional device of a catheter system with clot material in a blood vessel and withdrawing the interventional device and the portion of the clot material through a guide catheter. In some embodiments, the catheter system can include an attachment / valve member coupled to a proximal portion of the guide catheter, and the method can include unsealing the attachment / valve member to facilitate withdrawing the interventional device through the attachment / valve member without significant retention of clot material within the attachment / valve member. The method can further include resealing and aspirating the guide catheter before advancing another interventional device to the clot material to again engage and remove clot material from the blood vessel.

The invention is entitled "Systems for assisting delivery of mechanical endovascular therapeutic devices." The invention discloses a system for assisting delivery of mechanical endovascular therapeutic devices, wherein the system includes a first auxiliary device having a first linear sliding mechanism. The linear sliding mechanism includes a first non-slidable segment, a first slidable segment that is linearly displaceable relative to the first non-slidable segment, and a first tensioning device connected to the first slidable segment for movement therewith; the first tensioning device is convertible between an unsecured state and a secured state. A first securing hub is fixedly attached to the first non-slidable segment, wherein the first securing hub is convertible between an unsecured state and a secured state. The system can also include a second auxiliary device. The auxiliary devices provide enhanced control over movement of a delivery wire and / or a guide catheter.

The invention relates to a method and device for predicting the risk of restenosis after intravascular treatment of a TARAS patient, a storage medium and a program product. The method comprises the following steps: acquiring target preoperative clinical data and target iconography characteristics collected for a detection object; calculating a risk score based on the target preoperative clinical data and the target iconography features; the risk score is compared with a first threshold value, an auxiliary prediction result of the detection object is determined according to a comparison result, and the auxiliary prediction result is used for representing the restenosis risk of the detection object. The invention aims to provide a model for evaluating the post-PTA restenosis risk of a severe TARAS patient by using anatomical risk factors and other clinical risk factors, so that the risk of an intravascular treatment technology can be quantified, and the clinical popularization and application of the intravascular treatment technology can be promoted.

Systems and methods are provided for delivering a therapeutic agent to a target tissue via a vessel and sensing, in vivo, a characteristic of the therapeutic agent in the vessel. The characteristic indicates a concentration of the therapeutic agent in the vessel. The system preferably includes an occluder. The method preferably includes infusing the therapeutic agent distal of the occluder while the occluder is in an expanded configuration in the vessel.

An endovascular medical device system includes an elongated body, an expandable structure at a distal portion of the elongated body, and one or more electrodes. The expandable structure includes an expandable frame defining one or more apertures and each electrode is mechanically coupled to the expandable structure via a respective aperture of the one or more apertures. In some examples, each electrode defines a first maximum dimension in a first direction along a central longitudinal axis of the expandable structure and a second maximum dimension in a second direction transverse to the first direction, wherein the first maximum dimension is greater than the second maximum dimension. In some examples, when each electrode is mechanically coupled to the expandable structure, the respective aperture is configured to limit rotation of the respective electrode relative to the expandable structure.

An intravascular treatment device includes a catheter (101), and an exterior cage (102) fixed to a distal end of the catheter, the exterior cage radially expandable and including a stepped geometry portion of reduced diameter at a distal end thereof. The intravascular treatment device further includes a rod (107) extending within the catheter, the rod movable within the catheter so to extend through the distal end of the catheter into the exterior cage, and an inner actuation feature (105) having a proximal end fixed to the rod. The inner actuation feature is movable by the rod between a retracted state in which the inner actuation feature is contained within exterior cage and the cage is not radially expanded, and an advanced state in the inner actuation feature extends through the stepped geometry portion of the exterior cage so as to radially expand the exterior cage.

The present invention relates to an internal duct and fixing system (100) for branches for endovascular endoprostheses for endovascular treatment of aneurysms or dissections of the aorta, comprising (i) an endoprosthesis (200) provided with windows (210, 220, 230, 240), (ii) one or more occlusions (215, 225, 235, 245), fixed to the endoprosthesis (200) by means of suture (216, 226, 236, 246), reversibly occluding the windows (210, 220, 230, 240), and a set of fixing and duct elements (300) that forms one or more internal channels of the endoprosthesis (200), preferably in the region adjacent to one of the windows (210, 220, 230, 240). The present invention also relates to a corresponding endoprosthesis (200).

There is provided a device (100) for removing a clot from a vessel. The device (100) comprises a catheter body (110), a set of holes (120) and a lumen (130). The catheter body (100) is for insertion into the vessel. The catheter body (110) is attachable to an aspirator at a proximal end (111) of the catheter body (110). The catheter body (110) comprises an interior surface and an exterior surface. The catheter body (110) comprises a lumen (130) extending between the proximal end (111) and a distal end (112). The lumen (130) is configured to receive a guidewire (300). The set of holes (120) is towards the distal end (112) of the catheter body (110) in a distal region. The set of holes (120) is configured to engage the clot by suction. The set of holes (120) is arranged circumferentially on the catheter body (110). The distal region comprises a valve region (114) including a valve (115). The valve (115) is configured to close in response to pressure within the lumen being below a threshold value.

The present disclosure relates to medical devices including occlusion devices, clot retrieval systems, and stents. More particularly, the medical devices described herein measure characteristics for intravascular treatment sites. The medical devices may include pressure sensors and / or length sensors that may be used to determine the effectiveness of the medical devices during or after treatment. These sensors may be particularly helpful when used on an occlusion device or a clot removal device.

An intravascular therapy guidance system includes a processor circuit in communication with an extravascular imaging device. The processor circuit receives, from the extravascular imaging device, an extravascular image stream. The processor circuit determines a therapy region of a blood vessel in the extravascular image stream and outputs a screen display to a display in communication with processor circuit. The screen display includes the extravascular image stream of the blood vessel including movement of an intravascular therapy device within the blood vessel to deliver an intravascular therapy to the therapy region and a graphical representation of the therapy region overlaid on the extravascular image stream. The processor circuit determines, based on the extravascular image stream, whether the intravascular therapy device is aligned relative to the therapy region to deliver the intravascular therapy and modifies the screen display to indicate whether the intravascular therapy device is aligned to deliver the intravascular therapy.

An endovascular therapy system includes an endovascular device. The endovascular device includes an elongated body configured to be introduced into vasculature of a patient. The endovascular device includes an expandable structure at a distal portion of the elongated body. The therapy system (e.g., the endovascular device) can include a plurality of electrodes carried by the expandable structure. The elongated body can be configured to transform between a body delivery configuration and a body deployed configuration. In the body deployed configuration, the distal portion of the elongated body defines a coiled portion. The coiled portion can be located proximal of the expandable structure. The coiled portion is configured to limit or prevent an axial force applied to the elongated body from being transferred to the expandable structure or the plurality of electrodes when the expandable structure and the elongated body are positioned within the vasculature of the patient.

The present invention relates to an internal duct and fixing system (100) for branches for endovascular endoprostheses for endovascular treatment of aneurysms or dissections of the aorta, comprising (i) an endoprosthesis (200) provided with windows (210, 220, 230, 240), (ii) one or more occlusions (215, 225, 235, 245), fixed to the endoprosthesis (200) by means of suture (216, 226, 236, 246), reversibly occluding the windows (210, 220, 230, 240), and a set of fixing and duct elements (300) that forms one or more internal channels of the endoprosthesis (200), preferably in the region adjacent to one of the windows (210, 220, 230, 240). The present invention also relates to a corresponding endoprosthesis (200).

The present disclosure relates to medical devices including occlusion devices, clot retrieval systems, and stents. More particularly, the medical devices described herein measure characteristics for intravascular treatment sites. The medical devices may include pressure sensors and / or length sensors that may be used to determine the effectiveness of the medical devices during or after treatment. These sensors may be particularly helpful when used on an occlusion device or a clot removal device.

The present disclosure directs a catheter extension / pre-dilation system including an outer delivery sheath, an inner member extending within the sheath, and a mechanism for engaging and disengaging the inner member to the sheath. The inner member is configured with a tapered distal tip having a delivery microcatheter and a pre-dilation balloon member attached to the tapered distal tip near the microcatheter. The outer delivery sheath and the inner member are retrofitted for different engagement / disengagement mechanisms. The delivery microcatheter provides improved crossability for the balloon member to the treatment site in a non-invasive, quick and convenient manner. During a cardiac procedure, a guidewire and a guide catheter are advanced to the vicinity of the treatment site within a blood vessel. Subsequently, the inner member and the outer delivery sheath are advanced along the guidewire within the guide catheter to the treatment site in their engaged configuration. Once at the treatment site, the balloon member is inflated for pre-dilation treatment. Subsequently, the inner member is disengaged from the outer delivery sheath and retracted from the outer delivery sheath, and a stent is delivered to the treatment site within the outer delivery sheath.