The invention discloses a preparation method of a bionic carotid
artery blood vessel. The preparation method comprises the following steps: firstly, preparing a resin mode and a resin minor of the bionic carotid
artery blood vessel, filling the resin model and the resin minor with liquid-state
silica gel, and implementing curing and demoulding so as to obtain a
silicon rubber model and a
silicon rubber minor of the bionic carotid
artery blood vessel; assembling the
silicon rubber model, pouring de-ionized water into the assembled
silicon rubber model, and implementing ultra-low temperature freezing, so that a bionic carotid artery blood vessel ice model is formed; injecting a biological material water solution into the
silicon rubber minor of the bionic carotid artery blood vessel, implementing cross-linking treatment to separate semigel and model minor, so as to obtain a semi-hydrogel formed bionic carotid artery semicircular part; assembling the bionic carotid artery ice model and the semi-hydrogel formed bionic carotid artery semicircular part, pouring the biological material water solution, so that the ice model is unfrozen, and implementing cross-linking on the biological material solution to obtain a hydrogel, so that a hydrogel bionic carotid artery blood vessel is obtained; and pouring a
cell suspension into the hydrogel bionic carotid artery blood vessel so as to form a
cell layer on the inner surface of the hydrogel bionic carotid artery blood vessel, so that the bionic carotid artery blood vessel is formed. The bionic carotid artery blood vessel provided by the invention is profile-modeling and bionic.