58results about How to "Increase array density" patented technology

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

A device for detecting at least one substance of a fluid includes at least one piezo-acoustic resonator with at least one piezo layer, an electrode arranged on the piezo-electric layer, at least one other electrode arranged on the piezo-electric layer and a surface section used for sorption of the substance of the fluid. The piezo-electric layer, the electrodes and the surface section are disposed in such a way that electric control of the electrodes leads to an oscillation of the resonator at a resonance frequency which depends upon the amount of the substance which is sorbed on the surface section. The thickness of the pioelectric layer is in the region of 0.5 to 20 μm and the resonance frequency of the oscillation ranges from 500 MHz to 2 GHz. The device is a mass sensor with a piezo-acoustic high-frequency thin film resonator.

An array structure of single-level poly NMOS EEPROM memory cells and method of operating the array is discussed implemented in a higher density embedded EEPROM layout that eliminates the use of high voltage transistors from the array core region. If they are utilized, the high voltage transistors are moved to row and column drivers in the periphery region to increase array density with little or no added process complexity to allow economic implementation of larger embedded SLP EEPROM arrays. During program or erase operations of the array, the method provides a programming voltage for the selected memory cells of the array, and a half-write (e.g., mid-level) voltage to the remaining unselected memory cells to avoid disturbing the unselected memory cells of the array.

A multilayer well device includes a first substrate comprising an array of wells having a first pattern disposed therein and a second substrate comprising an array of wells having a second pattern, complementary to the first pattern disposed therein, wherein the second substrate is secured adjacent to a face of the first substrate. A common channel is interposed between the array of wells of the respective first and second substrates and is coupled to an inlet and an outlet.

There is provided a system and process for detecting biomolecular interaction on a substrate having a biomolecule immobilized on a surface of the substrate. The system and process incorporate a scanning Kelvin microprobe (SKM) capable of analyzing surface topography as well as a contact potential difference image signal. Also provided is the use of SKM in measuring and analyzing biochemical molecular interactions between a probe bound to the surface of the substrate, and a target suspected to be present in a liquid sample. One of the probe and target combination is a biomolecule such as a nucleic acid, a polypeptide, or a small molecule, and an antibody antigen combination may be used.

Methods and apparatus utilizing a stepped floating gate structure to facilitate reduced spacing between adjacent cells without significantly impacting parasitic capacitance. The stepped structure results in a reduced surface area of a first floating gate in close proximity to an adjacent floating gate with substantially no reduction in coupling area, thus facilitating a reduction in parasitic capacitance leading to improved gate coupling characteristics. Also, because of the reduced surface area exposed to adjacent floating gates, the floating gates may be formed with reduced spacing, thus further leading to improved gate coupling characteristics.

The invention discloses an optoacoustic/ultrasonic dual mode endoscope based on piezoelectric micromachined ultrasonic transducer arrays. The optoacoustic/ultrasonic dual mode endoscope includes a piezoelectric micromachined ultrasonic transducer (PMUT) array probe (2), a PMUT array element (1), an integrated circuit (3), a plane lens (4), a condenser lens (6), an optical fiber coupling collimator (7), a single-mode fiber (8), an optical fiber FC/APC connector (9), an optical fiber (10), a signal line (11) and an housing (12). The optoacoustic/ultrasonic dual mode endoscope is characterized in that, the piezoelectric micromachined ultrasonic transducers are adopted, the transducers and the integrated circuit are good in compatibility during manufacturing process, and the transducers are easy to form an array; transducer arrays are adopted, the endoscope does not need to rotate, the imaging speed is raised, real time imaging is achieved; and the multiple transducer arrays can effectively raise the signal to noise ratio of a signal, deep imaging through focusing and scanning is achieved. The optoacousitc/ultrasonic dual mode endoscope can be widely applied to fields of medical endoscopes and industrial flaw detection, and particularly has great application value in in-vivo scar tissue identification, assessment of damage of ablation of tissue, atherosclerotic degree assessment and the like.

A dynamic random access memory device includes a semiconductor substrate, a plurality of parallel word lines on the substrate, and a plurality of pairs of bit lines transverse to the word lines on the substrate. An array of one-transistor memory cells are selectively arranged at the cross points as defined between the word lines and the bit lines. The array is subdivided into a plurality of subarray sections. A sense amplifier section is connected to the bit lines. The sense amplifier section includes first and second sense amplifier circuits. Adjacent bit-line pairs of the bit lines include a first bit-line pair and a second bit-line pair, one of which has a folded bit-line arrangement being included in a certain subarray section to be connected to the first sense amplifier circuit, and the other of which has an open bit-line arrangement that extends into the subarray section and another subarray section adjacent thereto, and is connected to the second sense amplifier circuit.

The invention discloses a method for constructing a micro-nano structure with an antibacterial function on the surface of a metal substrate. The method comprises the following steps: carrying out technologies of metal surface cleaning, annealing heat treatment, lifting and drawing to prepare a ZnO seed crystal layer and hydrothermal growth of a nano array for surface treatment, and finally obtaining a metal plate target product with a ZnO nano array. The ZnO array prepared by the method has a large number of nanoscale tip array structures, the array density can reach 1*10 <7>-1*10 <9> pieces/cm <2>, and the tip diameter of nanorods forming the array ranges from 30 nm to 150 nm. The surface of the array can rapidly sterilize bacteria by making contact with bacterial strains, the surface bacteria can be killed within 1 minute, the sterilizing rate for the escherichia coli (ATCC 25922) and the staphylococcus aureus (ATCC 6538) can reach more than 99.99%, and the surface of the array has a rapid broad-spectrum bactericidal performance.

A solar cell package type with surface mount technology structure, comprising: a solar cell having a first electric terminal at the bottom thereof and a second electric terminal at the top thereof; at least a connection electric terminal capped at both sides of the solar cell in such a way that the top of the connection electric terminal is connected to the second electric terminal; and at least an insulation layer capped at both sides and partially placed at the bottom of the solar cell in such a way that it is interposed between the electric terminal and the solar cell for avoiding the short current and the water penetration. In this way, this package in accordance with the invention tends to increase the array density of the solar cells on the substrate and to minimize the manufacturing cost.