270 results about "Star polymer" patented technology

Conductive polymers having a star structure comprising a central core with multiple attachment sites and conjugated charge transporting arms radiating therefrom. The cores are derived from hyperbranched polymers, dendrimers, or other molecules with a multiplicity of attachment sites. The arms are derived from conjugated oligomers and polymers such as polythiophene, polyaniline or polyphenylene. The subject polymers allow assembly of the macromolecules in all three dimensions in the solid state. A ramification of the compact assembly is the realization of highly reflective, smooth coatings simply applied from solution. A preferred embodiment having a 1,3,5 hyperbranched polyphenylene core and poly (3-hexylthiophene) arms provides lustrous reflective gold coatings.

In one embodiment the present invention provides for a high thermal conductivity highly structured resin that comprises a host highly structured resin matrix, and a high thermal conductivity filler 30. The high thermal conductivity fillers are from 1-1000 nm in length, and high thermal conductivity fillers have an aspect ratio of between 3-100. Particular highly structured highly structured resins include at least one of liquid crystal 40 polymers, interpenetrating networks, dendrimer type matrices, expanding polymers, ladder polymers, star polymers and structured organic-inorganic hybrids 60.

Coatings for implantable medical devices comprising biologically absorbable or durable star polymers and methods for fabricating thereof are disclosed.

One aspect of the invention provides a degradable/biocompatible elastomer. The elastomer comprises a degradable cross-linked network of a hydrophobic, hydrolysable amorphous star polymer and a hydrophilic, biocompatible polymer. The network may be crosslinked thermally or by irradiation. In a preferred embodiment, the elastomer is used for a drug delivery system, and is particularly useful for delivery of peptide and protein drugs.

The invention belongs to the technical field of polymer material synthesis and preparation, relating to a star-shaped comb butadiene/styrene segmented copolymer, which is characterized in that the copolymer has the following structure: An-C, wherein A is the butadiene/styrene segmented copolymer, C is star-shaped seed tree coupler residue which is an epoxidation liquid star-shaped copolymer, n is branching degree which is larger or equal to 3, the number average molecular weight of the star-shaped comb segmented copolymer An-C is 5*10<4>-50*10<4>, the number average molecular weight of the segmented copolymer A is 1*10<4>-15*10<4>, the content of styrene is 55 percent to 85 percent (weight percent, same below), the content of butadiene is 15 percent to 45 percent, the content of 1, 2-structure is less than 30 percent (weight percent, which is counted by 100 percent of the total amount of monomer butadiene). The synthesis has the effect and benefit of simplifying the synthetic route of the star-shaped comb butadiene/styrene segmented copolymer, which can be widely applied to the preparation of the star-shaped comb butadiene/styrene segmented copolymer.

The invention discloses a star polymer nano-medicament carrier preparation used for intracellular medicament delivery. The nano-medicament carrier preparation is characterized by comprising the following components in part by weight: 1 to 20 parts of medicament, 10 to 200 parts of amphiphilic star segmented copolymer, and 20 to 500 parts of organic solvent, wherein the amphiphilic star segmented copolymer in the carrier is formed from hydroxyl-terminated star aliphatic polyester by connecting a hydrophilic segment through a disulfide bond. By using a self-assembling behavior of the copolymer in aqueous solution, nanoparticles of which internal hydrophobic layers coat the medicament can be prepared by a dialysis method. After entering cells, the nano-medicament carrier can prompt a hydrophilic shell thereof to drop selectively by using a reducing environment in tumor cells so as to realize localized release of the medicament in the tumor cells.

The invention discloses a biological adhesive which comprises a component a, and a component b, wherein the component a is a functional star polymer or/and a functional comb-like polymer, the functional star polymer is provided with one or more active groups, and the functional comb-like polymer is provided with one or more active groups; the component b is a functional polysaccharide which is provided with one or more active groups; and chemical reactions can be carried out between the active groups of the component a and the active groups of the component b so as to form novel chemical bonds. The invention further discloses a preparation method and application of the biological adhesive. The biological adhesive disclosed by the invention is a biocompatible adhesive (glue) formed by rapidly reacting the functional star polymer or/and comb-like polymer with lots of active groups and the functional polysaccharide. The adhesive based on the star polymer or/and comb-like polymer has a star or/and comb structure and has lots of active reactive groups, so that the gel forming reaction is fast, and the adhesive is reacted with tissues so as to realize an adhesive effect.

Lubricating oil compositions and viscosity index (VI) improver concentrates containing combinations of first polymers that are amorphous ethylene α-olefin copolymers; and second polymers that are star polymers, the arms of which are derived from diene, and optionally vinyl aromatic hydrocarbon monomer, wherein the star polymers have a Shear Stability Index (SSI) of from about 1% to about 35% (30 cycle).

The invention discloses a star polymer used as a lubricating oil viscosity index improver, a preparation method of the star polymer and application of the star polymer. The star polymer has asymmetrical arms and consists of two different types of polymer arms, wherein the first type of polymer arm is a hydrogenation polyisoprene homopolymer, and the second type of polymer arm is a copolymer in a hydrogenation polyisoprene-hydrogenation polybutadiene-polystyrene block structure; and in the copolymer arm, the polystyrene section is close to the core of the star polymer, the hydrogenation polybutadiene section is in the middle of the arm, and the hydrogenation isoprene section is outside the arm. The structure of the star polymer contains 2-15% of polybutadiene block by weight, and at least a part of the polyisoprene block and the polybutadiene block in the structure of the start polymer is hydrogenated. The star polymer has an excellent tackifying effect and excellent shear resistance stability, and is lower in pumping viscosity and low-temperature start viscosity during blending of thickened engine oil, and crystal or gel cannot be formed in the engine oil by the star polymer.

The invention relates to a novel preparation method and application of a cationic amphiphilic tetra-armed star polymer. In particular, the star polymer can be obtained through synthetic means such as atom transfer radical polymerization (ATRP) and click chemistry. A core of the star polymer is tetraphenylethylene with the characteristic of aggregation-induced emission. A polymer linear arm is a cationic amphiphilic random copolymer with excellent antibacterial effects. A covalently labeled T1 type magnetic resonance (MR) contrast agent is an organic gadolinium chelate. By using the cationic amphiphilic tetra-armed star polymer, fluorescence/MR double quantitative detection of Gram positive and negative bacteria with negative charges on the surfaces in the environment of pure water is achieved, and meanwhile good antibacterial effects are gained.

The invention discloses a chemically mechanical polishing solution and application thereof. The chemically mechanical polishing solution comprises star polymer containing pigment affinity group, ground granules, complexing agent, oxidant and water. By using the inventive polishing solution, flaws of copper billets can be reduced, partial and entire corrosion of the meal copper can be prevented, and the static corrosion velocity of copper at normal temperature and polishing temperature can be reduced under the condition of maintaining higher copper removal velocity.

Described herein are platinum-based brush-arm star polymers (Pt-BASPs), or a pharmaceutical composition thereof, for delivery of platinum-based agents, such as cisplatin. Also provided are methods and kits involving the Pt-BASPs, or a pharmaceutical composition thereof, for treating proliferative diseases such as cancers (e.g., lung cancer, head-and-neck cancer, esophagus cancer, stomach cancer, breast cancer, pancreas cancer, liver cancer, kidney cancer, or prostate cancer) in a subject.

Belonging to the technical field of biomedical polymer materials, the invention discloses a beta-cyclodextrin based amphiphilic pH responsive star polymer and a preparation method thereof, a micelle system based thereon, a composite material and application thereof. The polymer has a structure shown as the formula (1) in the specification, wherein x=3-20, y=2-30, z=5-35, and n=2-10. The polymer can be reduced in situ to obtain nanogold with small particle size and good stability. The invention also provides a micelle system based on the polymer, the micelle system has strengthened entrapment ability to water-insoluble drugs, can efficiently load hydrophobic drugs, gold nanoparticles and other substances, realizes the combination of tumor imaging diagnosis and tumor chemotherapy, and improves the therapeutic efficiency of cancer. And the polymer is easy to control the proportion of each block, and can be applied to preparation of the water-insoluble drug loaded micelle system to satisfy the release requirements of different drugs.

Polymers suitable for use as a viscosity index improver for lubricating oil compositions including linear polymers characterized by the formula:

D′-PA-D″;

• and star polymers characterized by the formula:

(D′-PA-D″)_n-X;

• wherein D′ represents an “outer” block derived from diene having a number average molecular weight of from about 10,000 to about 120,000 daltons; PA represents a block derived from monoalkenyl arene having a number average molecular weight of from about 10,000 to about 50,000 daltons; D″ represents an inner random derived from diene having a number average molecular weight of from about 5,000 to about 60,000 daltons; n represents the average number of arms per star polymer formed by the reaction of 2 or more moles of a polyalkenyl coupling agent per mole of arms; and X represents a nucleus of a polyalkenyl coupling agent.

The invention belongs to the technical field of high polymer chemistry and pharmaceutical preparations, relates to a synthesis and a micellization application of an amphiphilic beta-cyclodextrin (beta-CD) star polymer, and provides an amphiphilic beta-cyclodextrin (beta-CD) star polymer taking beta-cyclodextrin (beta-CD) as a core, acrylic acid and a methyl methacrylate copolymer as a lipotropy block and poly (N-vinyl pyrrolidone) as a hydrophilic block, and a synthesizing method of the amphiphilic beta-cyclodextrin (beta-CD) star polymer. The amphiphilic beta-cyclodextrin (beta-CD) star polymer is formed by connecting amphiphilic block polymers to 3-6 hydroxide radicals of the beta-cyclodextrin (beta-CD). The molar mass ratio of the acrylic acid and the methyl methacrylate in the lipotropy block and the poly (N-vinyl pyrrolidone) in the hydrophilic block in the amphiphilic polymer is 4:1:(1-15):1:16. The invention further relates to a vinpocetine micelle taking the amphiphilic beta-cyclodextrin (beta-CD) star polymer as a carrier material and a preparation method of the vinpocetine micelle. The medicine carrying micelle of the amphiphilic beta-cyclodextrin (beta-CD) star polymer provided by the invention has the characteristics of slow-release effect, pH sensitivity and lung targeting.