Method for individualized noninvasive calculation of blood flow of coronary arterybranches of patient in maximal congestion state

Abstract

The invention discloses a method for the individualized noninvasive calculation of the blood flow of coronary artery branches of a patient in a maximal congestion state, and relates to the field of biomechanics and hemodynamics. The method comprises the steps of obtaining physiological parameters, such as myocardial mass, heart rate and blood pressure, of the patient clinically; establishing a mathematical model for calculating the blood flow of coronary arteries in the maximum congestion state on the basis of an allometric growth rule; reconstructing a three-dimensional geometric model of thecoronary arteries on the basis of coronary artery CT images of the patient, measuring the vessel sizes and diameters of the coronary artery branches, and then obtaining the diversion ratio of each branch on the basis of the vessel sizes of the branches and the Poiseuille's law; combining the blood flow of the coronary arteries of the patient and the diversion ratio of each branch to obtain the blood flow of each coronary artery branch through calculation. By means of the method, the individualized blood flow of each coronary artery branch of the patient is calculated in a noninvasive mode, and more accurate boundary conditions can be provided for blood flow simulation of the coronary arteries.

Description

technical field [0001] The invention relates to the fields of biomechanics and hemodynamics, in particular to a hemodynamic numerical simulation technology, which can be used for setting individualized boundary conditions in the simulation calculation of human coronary artery hemodynamics. Background technique [0002] Coronary FFR technology is currently the "gold standard" clinically used to diagnose whether coronary stenosis causes downstream myocardial ischemia. FFR CT technology. coronary FFR CT The technology is based on the patient's coronary CT images, using numerical simulation methods to realize the hemodynamic simulation of the coronary arteries, and non-invasively obtaining the FFR value by extracting the upstream and downstream pressure values ​​of the stenotic coronary arteries, that is, FFR CT value. in FFR CT In the technology, the quality of coronary three-dimensional model reconstruction and the setting of fluid dynamics calculation boundary conditions...

AI Technical Summary

Problems solved by technology

The blood flow distribution method based on the length of branch vessels may ignore the difference in the shunt volume of vessels with the same length but different diameters, while the blood flow distribution method based on vessel diameters is more difficult in issues such as the diameter measurement position and the classification of branch vessels. complex, difficult to regularize

Therefore, considering any of these factors alone may cause errors

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