A biomimetic
intervertebral fusion device with a piezoelectric multifunctional
coating belongs to the field of implantable medical devices. It includes an upper piezoelectric multifunctional
coating, a fusion device body, and a lower piezoelectric multifunctional
coating. A bone graft window is located in the middle of the biomimetic
intervertebral fusion device. The piezoelectric multifunctional coating is made of electrospun piezoelectric PVDF / HA fibers, which are conformally adhered to the upper and lower surfaces of the fusion device body through a polydopamine
adhesive layer. The upper and lower surfaces of the fusion device body have a biomimetic curved surface configuration to match the morphology of the vertebral endplates, increasing the contact area and reducing
stress concentration at the fusion interface. While maintaining an
elastic modulus similar to
natural bone and good
radiation permeability, this fusion device, after implantation, can create a microenvironment conducive to
cell adhesion and proliferation. Under the influence of
cell traction,
ultrasonic stimulation, and the physiological load of the human
lumbar spine, it generates electrical stimulation signals, promoting
bone fusion, improving the stability of the fusion interface, and reducing the risk of postoperative loosening and
subsidence of the fusion device.