The invention belongs to the technical field of
antibacterial agent preparation, and provides an A-type
mannosylerythritol lipid nano-
emulsion as well as a preparation method and application thereof. The A-type mannosyrythritol lipid (MEL-A) is a biological surfactant with an amphiphilic characteristic, and comprises a hydrophilic group which takes 4-O-beta-D-mannopyranose-
erythritol as a main component and a hydrophobic group which takes a
fatty acid chain as a main component, and the A-type mannosyrythritol lipid (MEL-A) is a biological surfactant with an amphiphilic characteristic and comprises a hydrophilic group which takes 4-O-beta-D-mannopyranose-
erythritol as a main component. The MEL-A has a broad-spectrum antibacterial characteristic on various microorganisms (including
bacteria, fungi and yeasts). However, the water
solubility is low. Tween 20 and
glycerol monooleate are used as emulsifiers, and MEL-A is encapsulated in
emulsion particles to form oil-in-water
emulsion particles, so that the
solubility of MEL-A is improved, the antibacterial performance of A-type
mannosylerythritol lipid is not influenced, and the A-type
mannosylerythritol lipid is expected to be used in the field of
food safety protection.