45 results about "Mannosylerythritol lipid" patented technology

The invention relates to a young pigeon feed, which is obtained by mixing the following raw materials by weight: 20-45% of broiler feed material, 5-20% of corn, 5-10% of pea, 5-10% of bean cake, 1-3% of hemp seed, 6-12% of red soil, 2-4% of bentonite, 8-15% of yellow sand, 2-4% of salt, 2-8% of milk powder, 5-20% of bean meal, 1-3% of bone meal, 2-6% of edible oil, 1-2% of baking powder, 2-5% of phagostimulant, 2-6% of composite trace element, 1-5% of composite vitamin and 1-3% of additive, wherein the additive contains one or two of mannosylerythritol lipid or rhamnolipid. By addition of nutrient components of the young pigeon feed such as the additive, phagostimulant and the like, the feed disclosed by the invention is improved in taste, has a comprehensive nutrition, stimulates appetite of young pigeons and is beneficial to the growth of young pigeons.

The invention discloses a production method for mannosylerythritol lipids. The production method includes the steps: inoculating a seed culture solution with activated pseudozyma aphidis DSMZ70725 for seed culture, and separating to obtain bacterial cells after culture; inoculating a fermentation culture medium with the bacterial cells, carrying out fermentation culture for 7-15 d at the temperature of 28-30 DEG C, to obtain a fermentation liquid; and separating and purifying from the fermentation liquid to obtain the mannosylerythritol lipids, wherein the fermentation culture medium contains a vegetable oil. With the vegetable oil as a substrate and under the appropriate process, the mannosylerythritol lipids are produced through microbial cell transformation. The substrate used in the method is a renewable resource, the product is non-toxic and environmentally friendly, and the obtained fermentation liquid has high surface activity; in the fermentation process, mycelium clusters are small, the substrate is transformed fully, and the crude product yield is greatly improved; and the production process is safe, simple and convenient, and easy to operate, the product quality is high, and industrialized production is easy to realize.

The present invention includes as an active ingredient at least one biosurfactant, in particular mannosyl alditol lipid (such as MEL and MML) or triacylated mannosyl alditol lipid. This allows providing an activator and anti-aging agent that is excellent in activating and anti-aging effects on cells and that is safe enough to be used for a long time, and also providing cosmetics, quasi-drugs, drugs, and drinks and foods including the activator and the anti-aging agent as active ingredients. Further, the present invention provides MEL whose mannosyl erythritol skeleton in a molecular structure is 1-O-β-D-mannopyranosyl-meso-erythritol and a method for producing the MEL with use of a microorganism.

To provide safe and easy means for preventing or treating diseases of birds and mammals, in particular, livestock. In particular, to provide means for preventing or treating an infectious disease caused by a Gram-positive bacterium. In addition, to improve fermentation in the rumen of a ruminant animal, to contribute to suppression of the generation of greenhouse gas, and to increase the feed efficiency. Mannosylerythritol lipids (MEL) and/or rhamnolipids are given to birds or mammals.

The present invention provides a safe and easy means for preventing or treating diseases of birds and mammals, in particular, livestock. In particular, the present invention provides a means for preventing or treating an infectious disease caused by a Gram-positive bacterium. In addition, the invention aims to improve fermentation in the rumen of a ruminant animal, to contribute to suppression of the generation of greenhouse gas, and to increase the feed efficiency. Mannosylerythritol lipids (MEL) and/or rhamnolipids are given to birds or mammals.

The invention relates to a plant cosmetic preservative composition and a preparation method thereof. The plant cosmetic preservative composition includes a preservative mixture composed of a grapefruit seed extract, an origanum vulgare herb extract and a magnolia officinalis bark extract. The method is characterized in that a raspberry fruit extract and a sophora flower extract are employed to conduct preservative synergy on the preservative mixture. The preservative mixture, the raspberry fruit extract and the sophora flower extract are coated by a lipid material to form a sub-microparticle emulsion, and the lipid material is composed of mannosylerythritol lipid, sodium surfactin, hydrogenated lysolecithin and glycerin in a mass ratio of 5-10:1-3:3-5:20-50. The plant cosmetic preservative composition provided by the invention has low irritation, good preservative effect and effective components from natural plants, and is suitable for cosmetics.

The present invention relates to processes for the production of microbial glycolipids, mannosylerythritol lipids (MEL), from lignocellulosic carbon source. These processes are characterized in that the use of lignocellulosic materials for the production of a microbial glycolipids, MEL, comprising a fermentation preferably using fungi of the genus Pseudozyma or other microorganisms such as genetically modified fungi or bacteria. The processes for production of microbial glycolipids, MEL comprise three steps: pretreatment of lignocellulosic material; enzymatic hydrolysis; and fermentation. The enzymatic hydrolysis and fermentation may take place sequentially or simultaneously with addition of exogenous enzymes or simultaneously with enzymes produced by the microorganism itself. The produced microbial glycolipids have applications as: biosurfactants; antimicrobials; anticancer agents; wound healing factors; stabilizer agents on storage and purification of proteins or vaccines; drugs and gene deliver agents; antifreeze agents.

Corrosive effects arising during well treatment applications are inhibited and/or prevented by introducing into the well composition containing a corrosion inhibitor of a sophorolipid or a mannosylerythritol lipid or a combination thereof. The composition may also contain a corrosion inhibitor intensifier.

The invention discloses a preparation method for high-yield MEL (Mannosylerythritol lipids). The preparation method comprises the following steps: inoculating a fermentation culture medium with Pseudozyma aphidis DSMZ70725, and performing fermentation cultivation, so as to obtain the MEL, wherein vegetable oil is adopted as a substrate and a carbon source in the fermentation cultivation, and the ratio of C to N in the fermentation culture medium is (30-60):1. According to the invention, the yield of the MEL is increased through adjusting the ratio of C to N in the cultivation system, and the difficulty of low yield of the MEL prepared by adopting the preparation method is solved.

The invention discloses a heat-stable mannose erythritol lipid carrier, which is prepared by self-assembly of mannose erythritol lipid and lecithin in aqueous solution. The invention also provides the preparation method and application of the carrier. The carrier provided by the invention has thermodynamic stability, has better embedding effect on hydrophobic substances, and the materials used are safe and non-toxic, does not need other additives, and has simple and feasible preparation method and low cost.

The present invention relates to a solution solubilization composition of an insoluble material and a method for solubilizing an insoluble material using the same, on the basis of the mechanism that a solution solubilization composition of an insoluble material comprising mannosylerythritol lipid, an insoluble material, a heteropolysaccharide, a surfactant and a polyol offsets the intermolecular interaction of a hydrophobic material without physical requirements.

Provided is an oil-in-water emulsion composition which uses a mannosylerythritol lipid and imparts a favorable and stable sensation when applied. The oil-in-water emulsion composition is characterized in comprising the following components (A) to (C): a specific UV absorber (A), a sorbitan fatty acid ester (B) having an HLB of 6 or less, and a mannosylerythritol lipid (c). The HLB of a mixture of surfactants in the composition is less than 8, and the content ratio of component (A) relative to 100 parts by mass of the total amount of the oily components is at least 75 parts by mass.

The invention discloses a separation and purification method of mannosylerythritol lipids (MELs). The method is based on the difference in polarity of each component in crude MELs produced by fermentation, and utilizes a methanol-water-n-hexane ternary system to perform separation and purification on the MELs. The MELs are green bio-surfactants which are secondary metabolites produced by fermentation of Pseudozyma aphidis or Ustilago aphidis. The methanol-water-n-hexane ternary extraction system provided by the invention can effectively remove impurities such as grease and free fatty acids inthe crude MELs so as to realize efficient and quick separation and purification of the MELs, and the operation process is simple and efficient.

The invention discloses a method for purifying hydrophilic mannosylerythritol lipids (MELs). The hydrophilic MELs are prepared by performing acid hydrolysis on an MELs mixture obtained by fermentation in a methanol solution, meanwhile, free fatty acid as a main impurity in the hydrophilic MELs generates fatty acid methyl ester which can be removed through normal hexane extraction, and finally the high-purity hydrophilic MELs are obtained. The MELs is a glycolipid biosurfactant which is mainly produced by fermentation of saccharomycetes. According to the method provided by the invention, rapid preparation of hydrophilic MELs can be realized, free fatty acid in crude MELs can be efficiently removed, efficient and rapid separation and purification of the product can be realized, a new scheme is provided for purification of conventional structures of MELs, and industrial production and application of MELs can be promoted.

The present invention relates to methods for the enzymatic deacetylation of mannosylerythritol lipids produced by fermentation using lipases. More in particular, the present invention relates to a method for the enzymatic deacetylation of mannosylerythritol lipids using a hydrolyzing enzyme in an organic solvent containing only low amounts of water, preferably, no water. It further provides the use of organic solvents, containing only low amounts of water, more preferably, no water, for the enzymatic deacetylation of mannosylerythritol lipids.

The purpose of the present invention is to provide a highly hydrophilic synthetic fiber. The present invention pertains to the synthetic fiber in which (a) mannosylerythritol lipid (MEL) and (b) at least one glycerin compound selected from the group consisting of (poly)glycerin, (poly)glycerin fatty acid ester, and (poly)glycerin alkylene oxide adduct are adhered to the surface of the fiber.

The invention relates to a cold spraying modified layer and application thereof. In the process of preparing hydroxyapatite nano-powder, a surfactant is added to be beneficial to reducing the particle size of the nano-powder, and the change can optimize the biocompatibility, corrosion resistance and eye irritation of the cold spraying modified layer in later. However, after four different kinds of surfactants (sodium dodecyl benzene sulfonate, mannosylerythritol lipid, rhamnolipid and sophorolipid) are compared, it is found that the sodium dodecyl benzene sulfonate is not beneficial to the cytotoxicity and eye irritation of the modified layer of an artificial cornea titanium bracket, the reason possibly lies in that the whole preparation technology can hardly realize 100% removal of the surfactant, and compared with sodium dodecyl benzene sulfonate, mannosylerythritol lipid, rhamnolipid, sophorolipid and other glycolipid biosurfactants, proliferation and growth of cells are more facilitated.

The invention discloses a green organic insecticide and application of the green organic insecticide to prevention and treatment of vegetable pests, and the green organic insecticide is prepared from the following components in percentage by mass: malathion, abamectin, castor oil, tobacco oil, a mixed extracting solution of cinnamomum camphora bark, pomegranate rind and cacumen biotae, an organic solvent, a surfactant, a synergist and the balance of deionized water. The weight ratio of the cinnamomum camphora bark to the pomegranate bark to the cacumen biotae is 3: 2: 1.5, the organic solvent is methanol, and the surfactant is mannosylerythritol lipid. By adding the castor oil and the tobacco oil, a thin oil film can be formed on the surface of a crop, permeation of pesticide effect is facilitated, a more lasting protection effect is achieved, meanwhile, the pesticide can be easily attached to the body surface of red spiders, continuous action is facilitated, and the mostly killing effect is faster and better.