20 results about "Solanum nigrum" patented technology

This invention discloses a herbicidal composition containing propyzoxystrobin and chlorpyrifos, and its application, belonging to the field of pesticide technology. The active ingredients of this herbicidal composition are propyzoxystrobin and chlorpyrifos, with a weight ratio of propyzoxystrobin to chlorpyrifos of 1:5 to 5:1. Through the synergistic effect of the two active ingredients, this herbicidal composition addresses the seed dormancy and germination characteristics and resistance issues of black nightshade in pumpkin fields, achieving a synergistic control effect of "rapid-acting + long-lasting" and "closed + foliar" action. The control efficiency can reach over 80%, with an optimal ratio reaching as high as 93.1%. It also significantly increases pumpkin yield without adversely affecting pumpkin growth, solving the technical problems of the lack of dedicated control agents for black nightshade in pumpkin fields and the strong resistance of conventional agents in existing technologies.

The invention belongs to the field of new materials for daily use chemicals, and discloses a method for fermenting solanum nigrum, which is characterized in that solanum nigrum roots are fermented by adopting one or more strains of lactic acid bacteria, bifidobacteria, bacillus, micrococcus, saccharomycetes and filamentous fungi to obtain a solanum nigrum fermentation product. The functions of wrinkle resistance, compactness and the like of the withanolaria nipponica fermentation product obtained by fermentation through the method are obviously better than those of unfermented withanolaria nipponica fermentation products and fermentation products taking withanolaria nipponica extracts as fermentation bases. Meanwhile, the invention also provides application of the fermentation product.

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

The application relates to the technical field of plant grafting, and particularly discloses a grafting method capable of improving disease resistance of eggplants, which comprises the following steps: Solanum nigrum seedling, eggplant seedling, seedling period management and grafting; in the application, the wild Solanum nigrum is selected as the stock, has the advantages of fast growth speed and good disease resistance, and can greatly improve the disease resistance and yield of the plant as the stock; the eggplant has a high incidence rate during the growth process, especially the occurrence of the yellow wilt disease is serious, and the yield is completely lost in serious cases; the grafting can solve the fundamental problem; the Solanum nigrum seed has a large amount, is easy to breed, and has a high germination rate; the special nutrient solution is sprayed, the wound healing speed of the grafting is greatly accelerated, and the healing effect is good; the grafting method of the sleeve pipe is adopted, the grafting speed is improved, the wound is protected, and the bacteria are prevented from invading the wound.

This invention provides a traditional Chinese medicine preparation for promoting blood circulation and relieving pain, and its preparation method, relating to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from the following parts by weight of traditional Chinese medicine raw materials: 10-30 parts of Polygonatum sibiricum, 10-30 parts of Spatholobus suberectus, 10-30 parts of Curcuma longa, 5-20 parts of Sparganium stoloniferum, 5-20 parts of Areca catechu peel, 5-20 parts of Polygonum hydropiper, 5-20 parts of Rhizoma Scutellariae, 1-5 parts of Artemisia argyi, 5-20 parts of Solanum nigrum, 5-20 parts of Catechu, 10-30 parts of Scutellaria barbata, 5-20 parts of Aristolochia debilis, 10-30 parts of Astragalus membranaceus, and 5-20 parts of Artemisia argyi oil. The traditional Chinese medicine preparations described in this invention differ from those that typically enhance the efficacy of a single herb. Instead, they exhibit a synergistic relationship where one plus one equals more than two. The principal, assistant, adjuvant, and guide herbs complement each other, combining both tonifying and purging effects. This approach effectively promotes the dissipation of blood stasis, unblocks the flow of qi and blood in the meridians, eliminates local inflammation, and reduces swelling and pain. Simultaneously, it nourishes the tendons and bones, supports the body's vital energy, and enhances the body's ability to resist pathogens and repair damage. Thus, it comprehensively alleviates pain caused by various factors, achieving the goals of promoting blood circulation, removing blood stasis, clearing the meridians, reducing inflammation and swelling, and relieving pain.

The application relates to a protein SaNRAMP5 related to cadmium absorption of nightshade, a coding gene and application thereof. Knocking out the gene in nightshade can significantly reduce cadmium accumulation in nightshade, overexpressing the gene in Arabidopsis can promote cadmium accumulation in the root system of Arabidopsis, and expressing the gene in a cadmium-sensitive yeast ycf1 can significantly improve the sensitivity of the yeast strain to cadmium.

This invention relates to a composition for promoting hair growth and darkening hair, and a method for preparing the same. The composition comprises custard apple seeds, bitter thorn root, chicken bone incense, jujube kernel, sophora root, winter melon seeds, black nightshade fruit, oxalis, amla leaves, elm seeds, white pear leaves, coriander seeds, and shepherd's purse root; or the composition comprises bitter thorn root, chicken bone incense, sophora root, black nightshade fruit, oxalis, amla leaves, green jade fan, kangaroo claw flower, and Panax notoginseng. In some embodiments, the composition exhibits hair growth, darkening, and follicle activation effects comparable to or even better than the positive control.

This invention belongs to the field of biomedical materials and relates to a method for preparing a multi-dynamically bonded hydrogel based on polysaccharides from the traditional Chinese medicine *Solanum nigrum* and its application. *Solanum nigrum* is initially extracted and precipitated with alcohol to obtain crude polysaccharides. The polysaccharides are then deproteinized using the Sevag method to obtain a crude polysaccharide solution. After dialysis and freeze-drying, crude polysaccharide is obtained. The crude product is separated and purified to obtain homogeneous polysaccharides. The homogeneous polysaccharide solution is reacted with sodium periodate solution in the dark, followed by dialysis, purification, and freeze-drying to obtain oxidized *Solanum nigrum* polysaccharide OBY. OBY is dissolved in boric acid solution to obtain solution A. Carboxymethyl chitosan is dissolved in polyvinyl alcohol solution to obtain solution B. After the solutions A and B have fully reacted, they are placed in a mold to obtain a multi-dynamically bonded hydrogel based on *Solanum nigrum* polysaccharides. This hydrogel can be applied to the preparation of drugs for chronic wound repair, providing a novel material system and application strategy for developing new wound dressings with excellent physicochemical properties, intelligent response characteristics, and active repair functions.

The invention discloses a traditional Chinese medicine composition for treating liver cancer and a preparation method thereof, the traditional Chinese medicine composition takes turtle shell as a monarch drug, astragalus membranaceus, curcuma zedoary, oyster and nightshade as ministerial drugs, radix pseudostellariae for tonifying qi and nourishing yin, lucid ganoderma for nourishing qi and blood and enhancing the effect of astragalus membranaceus for tonifying healthy qi, oldenlandia diffusa for clearing away heat and toxic materials, akebia fruit for regulating qi, activating blood and removing stasis, and the traditional Chinese medicine composition has the effects of clearing heat and removing toxicity. The capacities of the monarch drug and the ministerial drug for removing stasis toxin and dissipating abdominal mass are enhanced; raw liquorice is used as a conductant drug for regulating the drug property. The traditional Chinese medicine composition has the effects of soothing the liver, strengthening the spleen, tonifying qi and activating blood for liver cancer patients, and can also soften hard lumps, dissipate stagnation, clear away heat and toxic materials, nourish yin, promote salivation, clear deficiency heat and improve the life quality of the patients. The Chinese herbal medicine composition disclosed by the invention is simple in preparation method, easy to popularize, high in compliance in the aspect of anti-liver cancer use, high in tumor inhibition rate, exact in curative effect and safe in clinical application, and has important significance in treatment of liver cancer.

The present application relates to a kind of steroid compound and its application in treating neurodegenerative diseases, the steroid compound has the structure shown in formula I: The steroid compound of structure I is isolated from the whole grass of Solanum nigrum by yeast fermentation for the first time, it shows better neurotrophic factor (NGF) activity and acetylcholinesterase inhibitory activity, is expected to be developed as the drug or functional food of neurotrophic and neuroprotective function, for treating neurodegenerative diseases (such as senile dementia).

This invention relates to a plant composition with whitening effects and its application. The whitening plant composition includes extracts of *Scleroderma wilfordii*, *Myrothamnus flabellifolia*, and *Solanum nigrum* root. The whitening plant composition of this invention utilizes the combination of three plant extracts, resulting in a rational formulation where each active ingredient complements the others, synergistically enhancing their effects. This effectively inhibits tyrosinase activity and reduces melanin synthesis, exhibiting significant whitening efficacy. When applied to cosmetics, this plant composition results in stable products that also provide skin repair, reduce the irritation of whitening ingredients, and are suitable for various skin types, fully meeting consumers' demand for natural, gentle, and highly effective whitening products.

This invention belongs to the field of cosmetic technology, specifically relating to a hair care composition for improving damaged hair and its application. It includes extracts of *Ulva prostrata*, *Solanum nigrum* root, and *Camellia chrysantha* flowers, with a mass ratio of (1-2):(3-5):(1-3). This invention achieves a synergistic repair effect on damaged hair. The composition can effectively penetrate into the hair shaft, replenishing lost nutrients and enhancing hair's resilience and elasticity; simultaneously, it smooths raised cuticles, significantly reducing resistance during combing, making hair smooth and easy to comb, and noticeably improving hair shine for a healthier and shinier appearance. The composition also has excellent antioxidant properties, helping to slow down further damage to hair caused by external factors, comprehensively improving hair health from multiple dimensions, and is gentle and non-irritating, suitable for long-term use.

The invention discloses a method for repairing cadmium-polluted soil based on combination of chitosan nanoparticles and nightshade, which comprises the following steps: S1, collecting a soil sample, and testing whether the concentration of cadmium in the soil sample reaches a preset concentration or not for later use; s2, dissolving chitosan in an acetic acid solution, adjusting the pH value, and stirring the solution overnight until the chitosan is completely dissolved and the solution is clear; adding sodium tripolyphosphate, filtering the mixed solution to obtain a suspension, centrifuging, washing, and drying by a freeze dryer to obtain chitosan nanoparticles; s3, accelerating germination of the black nightshade seeds, and transplanting seedlings into the cadmium-containing soil in the step S1 when the seedlings grow to 2-3 cm; after the plants grow for two weeks, spraying chitosan nanoparticle solutions with different concentrations on leaves. According to the method, through the combined effect of the chitosan nanoparticles and the black nightshade, the result shows that the activity of cadmium in soil can be improved through the nano chitosan with the proper concentration, and the Cd extraction and enrichment capacity of the black nightshade is improved.

The application discloses a Talaromyces purpureogenus and application thereof in weeding, and belongs to the technical field of bioengineering and weeding, wherein the Talaromyces purpureogenus is named as CY-1, is preserved in the China General Microbiological Culture Collection Center, and has a preservation date of May 23, 2022 and a preservation number of CGMCC No.40203. Metabolic products of the Talaromyces purpureogenus CY-1 in the application can effectively inhibit broadleaf weeds such as amaranthus retroflexus, alternanthera philoxeroides, xanthium, chenopodium album, solanum nigrum, bidens pilosa, comphre, sonchus oleraceus, pteris cretica, medicago sativa, ipomoea hederifolia, rumex patientia, galium aparine, abutilon theophrasti, portulaca oleracea, leonurus japonicus, veronica anagallis, and aster spathulifolius, and the Talaromyces purpureogenus CY-1 is green and efficient in weeding, and has a wide application prospect in weeding.

The application discloses a kind of solanum nigrum three-dimensional planting automation illumination adjusting systems, including three-dimensional planting structure and adjustable illumination mechanism, the three-dimensional planting structure includes bottom plate, and two side frames are fixedly connected in the top surface of bottom plate both sides;In the illumination assembly of the application, the height position of LED light bar can be adjusted in the height direction by adjusting the position of U-shaped frame, and the light angle can be adjusted by rotating the rotating plate with LED light bar, so that the light blind area is avoided, and the functionality is stronger, and meanwhile, the multiple rotating sleeves in the planting layer frame assembly can rotate slowly, so that solanum nigrum can slowly rotate during cultivation, so that each position can receive light;The illumination assembly can reciprocate in vertical direction, so that the LED light bar on the illumination assembly will reciprocate vertically, so that after adjusting the position of LED light bar, whether to reciprocate for illumination to increase the light area can be selected according to the growth condition of solanum nigrum, so that solanum nigrum can also meet large-area illumination in later growth.

The application discloses a traditional Chinese medicine composition for treating triple-negative breast cancer and a preparation method and application thereof. The traditional Chinese medicine composition is composed of Ranunculus japonicus, Alocasia cucullata, centipede, Prunella vulgaris, Curcuma zedoaria, Sparganium stoloniferum, Schisandra chinensis, Euphorbia neriifolia, Solanum nigrum, green calyx, Albizia julibrissin, pericarpium citri reticulatae, Radix Clematidis, Radix Paeoniae Alba, fried Atractylodes, and Rhizoma Belamcandae. The application is aimed at the pathogenesis of triple-negative breast cancer, i.e. liver depression, qi stagnation, phlegm and blood stasis, and deficiency of healthy qi. The whole prescription has the functions of soothing liver and relieving depression, resolving phlegm and removing stasis, promoting blood circulation and removing blood stasis, and supporting healthy qi and resisting cancer. Pharmacodynamic experiments show that the traditional Chinese medicine composition can increase the expression level of DNA damage marker gamma-H2AX, and promote cell apoptosis by inducing DNA damage of tumor cells.

This invention belongs to the field of microbial technology, and particularly relates to a *Panthera* strain N16 and its application in the degradation of solanine. A *Panthera* strain ( Pantoea strain N16, of the Pantotheca genus (sp.) Pantoea The preservation number of strain N16 (sp.) is GDMCC NO: 67883. The Pantotheca strain N16 provided by this invention can simultaneously and efficiently degrade α-solanine and α-carboxine, exhibits no hemolytic activity, does not carry resistance plasmids, and maintains high degradation activity in the 30-45 °C range. It can be widely applied in potato food processing, feed detoxification, and storage quality control, providing a safe, efficient, and low-cost microbial resource for the remediation of solanine pollution.

The invention relates to the technical field of traditional Chinese medicines, in particular to a body resistance strengthening and detoxification traditional Chinese medicine composition for adjuvant therapy of AIDS, which comprises the following components in parts by weight: 10-20 parts of ginseng, 20-30 parts of astragalus membranaceus, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of poria cocos, 10-20 parts of angelica sinensis, 1-5 parts of rice worm, 2-12 parts of cordyceps cicadae, 10-30 parts of welted thistle, 12-18 parts of honeysuckle stem and 8-12 parts of shrub althea flower. The traditional Chinese medicine composition is prepared from 25-35 parts of spreading hedyotis herb, 10-20 parts of purslane herb, 10-20 parts of black nightshade herb, 2-12 parts of liquorice root, 2-12 parts of ginger, 15-25 parts of suberect spatholobus stem, 5-15 parts of ginkgo leaf, 10-20 parts of snakegourd fruit and 5-15 parts of water chestnut. The traditional Chinese medicine composition can be used for assisting in treating AIDS, enhancing the immunity of the organism, improving clinical symptoms and improving the life quality of patients.

The application discloses a kind of spirocyclic amino acid skeleton compounds, it is compound shown as formula I with structural general formula, there are 29 kinds of compounds.The application also discloses the preparation method of spirocyclic amino acid skeleton compound.The application also discloses the application of spirocyclic amino acid skeleton compound in as or preparation herbicide, in the application in weed control or preparation in weed control preparation, the control object or weed of the herbicide is selected from the group consisting of barnyard grass, dogtail grass, Chinese alpine paper, crabgrass and other monocotyledonous plants, and purslane, amaranthus retroflexus, goosefoot, solanum nigrum, abutilon theophrasti and other dicotyledonous plants.Spirocyclic amino acid skeleton compound of the application is obtained after molecular modification to microsphaeropsis ochracea ketonic acid, and experimental research shows that the weed control effect is good, especially compound C3, compound C22, compound C23, the growth of crop has no influence basically.Spirocyclic amino acid skeleton compound of the application is suitable for industrial production, and has great application potential.

The invention provides an impurity adsorption type dispersive solid-phase extraction agent MOF-808 and application thereof in solanine detection, and the impurity adsorption type dispersive solid-phase extraction agent MOF-808 can be used for purifying a sample pretreatment extracting solution. The MOF-808 provided by the invention shows impurity adsorption capacity due to high specific surface area, adjustable aperture and easy-to-functionalize surface chemical properties, realizes purification of a sample extracting solution, has the advantages of simplicity and convenience in operation, high efficiency, low cost and the like when being applied to pretreatment of a sample during solanine detection, and has a wide application prospect. Therefore, the subsequent accurate detection of the solanine is facilitated.