54 results about "Solanum nigrum" patented technology

The invention belongs to the technical field of biology, and relates to a heavy metal tolerant sphingomonas strain 1PPS-Zn1 and application thereof, the heavy metal tolerant sphingomonas strain 1PPS-Zn1 is preserved in China Center for Type Culture Collection on March 20, 2025, the preservation number is CCTCC NO: M 2025544, the sphingomonas strain 1PPS-Zn1 can adsorb and tolerate high-concentration zinc, the highest tolerable concentration reaches 80 mmol / L, and the sphingomonas strain 1PPS-Zn1 also has the capabilities of producing IAA, fixing nitrogen and promoting plant growth, and can be applied to the field of heavy metal tolerant plants. And the absorption, enrichment and transfer capabilities of the black nightshade to heavy metal zinc in the soil can be improved, finally, the remediation efficiency of the zinc-polluted soil is improved, a new way is provided for soil remediation and ecological environment remediation, and the method has wide development and application prospects.

The invention provides a traditional Chinese medicine preparation for treating chronic prostatitis, and relates to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine preparation is prepared from black nightshade, hypericum perforatum, yam rhizome, rhizoma sparganii, common sage herb, chingma abutilon seed, polyporus umbellatus, uniflower swisscentaury root, corydalis amabilis, aspongopus, glossy privet fruit, fructus broussonetiae, radix ophiopogonis, tuber fleeceflower stem, day lily and liquorice. The traditional Chinese medicine preparation has the effects of clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis, nourishing yin and soothing nerves and tonifying liver and kidney. The traditional Chinese medicine preparation disclosed by the invention has a remarkable treatment effect on CNP rats, and the prostate pathological injury condition and inflammatory response of the CNP rats are effectively relieved. In addition, the traditional Chinese medicine composition has a good treatment effect on relieving pain, frequent micturition, urgent urination, dysuria and other clinical symptoms and inflammation conditions of patients, and has a high total treatment effective rate on chronic prostatitis. The traditional Chinese medicine preparation provides a new scheme for treating chronic prostate.

This invention discloses a herbicidal composition containing propyzoxystrobin and chlorpyrifos, and its application, belonging to the field of pesticide technology. The active ingredients of this herbicidal composition are propyzoxystrobin and chlorpyrifos, with a weight ratio of propyzoxystrobin to chlorpyrifos of 1:5 to 5:1. Through the synergistic effect of the two active ingredients, this herbicidal composition addresses the seed dormancy and germination characteristics and resistance issues of black nightshade in pumpkin fields, achieving a synergistic control effect of "rapid-acting + long-lasting" and "closed + foliar" action. The control efficiency can reach over 80%, with an optimal ratio reaching as high as 93.1%. It also significantly increases pumpkin yield without adversely affecting pumpkin growth, solving the technical problems of the lack of dedicated control agents for black nightshade in pumpkin fields and the strong resistance of conventional agents in existing technologies.

The invention belongs to the field of new materials for daily use chemicals, and discloses a method for fermenting solanum nigrum, which is characterized in that solanum nigrum roots are fermented by adopting one or more strains of lactic acid bacteria, bifidobacteria, bacillus, micrococcus, saccharomycetes and filamentous fungi to obtain a solanum nigrum fermentation product. The functions of wrinkle resistance, compactness and the like of the withanolaria nipponica fermentation product obtained by fermentation through the method are obviously better than those of unfermented withanolaria nipponica fermentation products and fermentation products taking withanolaria nipponica extracts as fermentation bases. Meanwhile, the invention also provides application of the fermentation product.

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

The invention relates to a salt-tolerant bacillus strain EMM919, which is preserved in the China Center for Type Culture Collection on April 25, 2025, and the preservation number is CCTCC NO: M 2025879. The salt-tolerant bacillus strain EMM919 has the advantages that the salt-tolerant bacillus strain EMM919 is preserved in the China Center for Type Culture Collection on April 25, 2025; the nucleotide sequence of the strain comprises a 16S rRNA (ribosomal Ribonucleic Acid) gene sequence and a gyrB gene sequence. The bacterial strain can be used for preparing microbial pesticides and seed dressing agents for preventing and treating fusarium solani EMF893, neurospora EMF992, cylindrospora robusta EMF882, fusarium laminatum EMF998, alternaria alternata EMF993, botryosphaeria dothidea EMF899, solanum nigrum EMF990, phomopsis EMF898 and fusarium graminearum EMF897. The content of viable bacteria in the liquid pesticide is 2 * 10 < 9 >-5 * 10 < 9 > CFU / mL, and the content of viable bacteria in the solid pesticide is 2 * 10 < 9 >-8 * 10 < 9 > CFU / g. In the liquid seed-dressing agent, the content of viable bacteria is 2 * 10 < 9 >-5 * 10 < 9 > CFU / mL, and in the solid seed-dressing agent, the content of viable bacteria is 2 * 10 < 9 >-8 * 10 < 9 > CFU / g.

A traditional Chinese medicine compound for nourishing yin, clearing heat and removing blood stasis for treating primary Sjögren's syndrome combined with renal tubular acidosis and its preparation method, belonging to the field of traditional Chinese medicine compound preparations. The traditional Chinese medicine compound for nourishing yin, clearing heat and removing blood stasis is composed of Achyranthes bidentata, Rhizoma Alismatis, Radix Rehmanniae, Radix Angelicae Sinensis, Fructus Cuscutae, Fructus Rosae Laevigatae, Fructus Cuscutae, Rhizoma Gentianae, Rhizoma Phragmites, Cortex Moutan, Solanum nigrum, Astragalus, Plantago, Dendrobium, Atractylodes, Fructus Corni, Leonurus japonicus, and Licorice. This disease is a syndrome of deficiency in the root and excess in the superficial, or a mixture of deficiency and excess, with kidney yin deficiency as the root and damp-heat and blood stasis as the superficial, the two being mutually causal. Kidney yin deficiency leads to the internal generation of virtual fire, burning body fluid and causing dryness. In addition, due to the internal heat of yin deficiency, the body fluid is refined into phlegm, which accumulates in the three energizers, obstructing the qi flow, generating internal damp heat. The damp heat is long-term trapped in the kidney meridians, causing qi stagnation and blood stasis, forming a state of "dampness, heat, and blood stasis" obstruction, ultimately presenting a syndrome of deficiency in the root and excess in the superficial, or a mixture of deficiency and excess. Therefore, the present invention combines these drugs to produce a synergistic effect on the efficacy of each drug, thereby achieving the effects of nourishing yin and tonifying the kidney, clearing away heat and dampness, and promoting blood circulation and removing blood stasis.

The application relates to the technical field of plant grafting, and particularly discloses a grafting method capable of improving disease resistance of eggplants, which comprises the following steps: Solanum nigrum seedling, eggplant seedling, seedling period management and grafting; in the application, the wild Solanum nigrum is selected as the stock, has the advantages of fast growth speed and good disease resistance, and can greatly improve the disease resistance and yield of the plant as the stock; the eggplant has a high incidence rate during the growth process, especially the occurrence of the yellow wilt disease is serious, and the yield is completely lost in serious cases; the grafting can solve the fundamental problem; the Solanum nigrum seed has a large amount, is easy to breed, and has a high germination rate; the special nutrient solution is sprayed, the wound healing speed of the grafting is greatly accelerated, and the healing effect is good; the grafting method of the sleeve pipe is adopted, the grafting speed is improved, the wound is protected, and the bacteria are prevented from invading the wound.

This invention provides a traditional Chinese medicine preparation for promoting blood circulation and relieving pain, and its preparation method, relating to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from the following parts by weight of traditional Chinese medicine raw materials: 10-30 parts of Polygonatum sibiricum, 10-30 parts of Spatholobus suberectus, 10-30 parts of Curcuma longa, 5-20 parts of Sparganium stoloniferum, 5-20 parts of Areca catechu peel, 5-20 parts of Polygonum hydropiper, 5-20 parts of Rhizoma Scutellariae, 1-5 parts of Artemisia argyi, 5-20 parts of Solanum nigrum, 5-20 parts of Catechu, 10-30 parts of Scutellaria barbata, 5-20 parts of Aristolochia debilis, 10-30 parts of Astragalus membranaceus, and 5-20 parts of Artemisia argyi oil. The traditional Chinese medicine preparations described in this invention differ from those that typically enhance the efficacy of a single herb. Instead, they exhibit a synergistic relationship where one plus one equals more than two. The principal, assistant, adjuvant, and guide herbs complement each other, combining both tonifying and purging effects. This approach effectively promotes the dissipation of blood stasis, unblocks the flow of qi and blood in the meridians, eliminates local inflammation, and reduces swelling and pain. Simultaneously, it nourishes the tendons and bones, supports the body's vital energy, and enhances the body's ability to resist pathogens and repair damage. Thus, it comprehensively alleviates pain caused by various factors, achieving the goals of promoting blood circulation, removing blood stasis, clearing the meridians, reducing inflammation and swelling, and relieving pain.

The invention relates to the technical field of medicine compositions, and discloses a Uighur medicine composition for treating urinary system infection, a preparation as well as a preparation method and application of the Uighur medicine composition. Comprising the following components in parts by weight: 15-20 parts of chinaroot greenbrier root, 15-20 parts of chinaroot greenbrier, 5-10 parts of Japanese polypody rhizome, 5-10 parts of folium sennae, 3-5 parts of fennel, 3-5 parts of myrobalan, 3-5 parts of black wood chips, 3-5 parts of swertia pseudochinensis, 3-5 parts of fructus chebulae immaturus, 2-4 parts of rose petals, 2-4 parts of humifuse euphorbia herb, 2-4 parts of sandalwood, 2-4 parts of impatiens balsamina leaves, 2-4 parts of black nightshade fruit, 1-3 parts of pimpinella diversifolia fruit, 1-3 parts of chamomile, 1-3 parts of anchusa, 1-3 parts of The Uighur medicine composition can effectively inhibit growth of pathogenic bacteria such as Escherichia coli and the like, can remarkably inhibit inflammation in bladder, urethra and kidney in a urinary system, has a remarkable effect on treatment of urinary system infection, and is simple and convenient in preparation method and suitable for industrial production.

The invention relates to application of a traditional Chinese medicine composition in preparation of a medicine for preventing or treating myelodysplastic syndrome and related complications thereof. The traditional Chinese medicine composition comprises sculellaria barbata, astragalus membranaceus, angelica sinensis, nightshade, radix curcumae, red ginseng, duchesnea indica, saussurea involucrata, cyclea verticillata and salvia miltiorrhiza. The traditional Chinese medicine composition has a good prevention and treatment effect on myelodysplastic syndrome and related complications thereof, can effectively inhibit proliferation of hematological tumor cells, and also can inhibit proliferation of the myelodysplastic syndrome by increasing the hemoglobin level, reducing the inflammatory cytokine level and reducing the proportion of peripheral blood T cells. Anemia, inflammation and low immune function caused by the myelodysplastic syndrome can be treated. The invention provides an effective strategy for prevention or treatment of myelodysplastic syndrome and related complications thereof, and provides a new direction for application of the traditional Chinese medicine composition.

The application relates to a protein SaNRAMP5 related to cadmium absorption of nightshade, a coding gene and application thereof. Knocking out the gene in nightshade can significantly reduce cadmium accumulation in nightshade, overexpressing the gene in Arabidopsis can promote cadmium accumulation in the root system of Arabidopsis, and expressing the gene in a cadmium-sensitive yeast ycf1 can significantly improve the sensitivity of the yeast strain to cadmium.

The invention relates to a pharmaceutical composition for treating respiratory diseases and a use method thereof, and belongs to the technical field of respiratory disease treatment. The pharmaceutical composition comprises the following components in parts by weight: 10-15 parts of viola tianshanensis, 10-15 parts of hollyhock flower, 10-15 parts of platycodon grandiflorum, 10-15 parts of calyx seu fructus physalis and 10-15 parts of nightshade fruit. According to the traditional Chinese medicine composition, through matching of a nike cataplasm therapy and the medicine composition, medicine components directly reach upper and lower airways and even pulmonary alveoli, the local treatment effect is directly achieved, the medicine effect is fast, the respiratory tract is not stimulated, the used Uighur medicine does not contain hormone components, compared with a traditional systemic medicine, the side effect is smaller, and compared with the prior art, the traditional Chinese medicine composition has great advantages.

The invention discloses a traditional Chinese medicine targeting pellet composite tablet for treating testicular cancer and a preparation method of the traditional Chinese medicine targeting pellet composite tablet. The traditional Chinese medicine targeted pellet composite tablet is prepared from the following raw materials: solanum nigrum alkaloid, patrinia terpene, thunberg fritillary bulb sterol, astragalus polysaccharide, albiflorin, angelica polysaccharide, tangerine seed volatile oil, fennel terpene, mesoporous silica nanoparticles, a carrier material and an enteric-coated material. According to the invention, tumor targeting and microenvironment response drug release functions are reserved, and a time sequence synergistic effect of cancer resistance and immunoregulation is realized.

The invention relates to an efficient plant genetic transformation vector based on rhizobium rhizogenes, which is modified on the basis of a pTi vector, and a left boundary pTi-LB and a right boundary pTi-RB of T-DNA of the vector are respectively replaced by a left boundary pRi-LB and a right boundary pRi-RB; deleting a Hyg expression cassette in the T-DNA region, and connecting a target gene expression cassette to the front end of the original RUBY expression cassette; a VirGN54D insert element is inserted between an Ori element and an SmR element in a non-T-DNA (Transfer-Deoxyribose Nucleic Acid) region; the 106th site of a RepA protein coding gene sequence in pVS1 of a non-T-DNA region is mutated into a histidine coding sequence from an arginine coding sequence. The invention aims to enhance efficient genetic transformation of plant exogenous genes in multiple species, has broad-spectrum adaptability to plant species, and particularly has obvious effects in multiple plant species which depend on genotypes and are difficult to transform, such as cucumbers, white radishes, broad beans, Chinese little greens, black nightshade, pokeberry roots, gingko, phalaenopsis, Chinese roses, Chinese pines and the like.

The invention relates to a method for repairing cadmium-polluted soil by using hyperaccumulator nightshade, which comprises the following steps: S1, experimental design: transplanting nightshade seedlings into polluted soil with different cadmium concentrations, setting a plurality of cadmium concentration gradients, and applying nitric oxide (NO) solutions with different concentrations in the growth period of nightshade; s2, data processing and analysis: measuring biomass, cadmium content and stress resistance index of each organ of the black nightshade and soil cadmium content, and carrying out statistical analysis. Compared with a traditional contaminated soil treatment method, the technical scheme has the advantages of being low in treatment cost, small in work amount, high in operability, easy to popularize in a large area and the like.

This invention relates to a composition for promoting hair growth and darkening hair, and a method for preparing the same. The composition comprises custard apple seeds, bitter thorn root, chicken bone incense, jujube kernel, sophora root, winter melon seeds, black nightshade fruit, oxalis, amla leaves, elm seeds, white pear leaves, coriander seeds, and shepherd's purse root; or the composition comprises bitter thorn root, chicken bone incense, sophora root, black nightshade fruit, oxalis, amla leaves, green jade fan, kangaroo claw flower, and Panax notoginseng. In some embodiments, the composition exhibits hair growth, darkening, and follicle activation effects comparable to or even better than the positive control.

The invention provides a blood-activating and pain-relieving traditional Chinese medicine preparation and a preparation method thereof, and relates to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of rhizoma polygonati, 10-30 parts of caulis spatholobi, 10-30 parts of turmeric, 5-20 parts of rhizoma sparganii, 5-20 parts of pericarpium arecae, 5-20 parts of fructus polygoni orientalis, 5-20 parts of glabrous sarcandra herb, 1-5 parts of short-pedicel aconite root, 5-20 parts of black nightshade herb, 5-20 parts of catechu, 10-30 parts of cudrania cochinchinensis, 5-20 parts of herba aristolochiae, 10-30 parts of radix hedysari and 5-20 parts of artemisia argyl oil. The multiple traditional Chinese medicine preparations are different from a common enhanced single medicine in efficacy, a one-plus-one-greater-than-two synergistic relationship is adopted, monarch, minister, assistant and guide complement each other, purgation and tonification are combined, blood stasis dissipation can be effectively promoted, channels and collaterals are unblocked, local inflammation is eliminated, swelling and pain are relieved, meanwhile, muscles and bones are nourished, healthy qi is supported, and the curative effect is good. Therefore, the pain caused by various factors is comprehensively relieved, and the purposes of promoting blood circulation to remove blood stasis, dredging the channels, diminishing inflammation and swelling, and easing and relieving pain are achieved.

The invention discloses a solanum nigrum three-dimensional planting automatic illumination adjusting system which comprises a three-dimensional planting structure and an adjustable illumination mechanism, the three-dimensional planting structure comprises a bottom plate, and two side frames are fixedly connected to the top surfaces of the two sides of the bottom plate; the position of a U-shaped frame in the illumination assembly can be adjusted in the height direction to adjust the height position of an LED lamp strip, meanwhile, a rotating plate can drive the LED lamp strip to rotate to adjust the illumination angle, in this way, illumination blind areas are avoided, functionality is higher, meanwhile, a plurality of rotating sleeves in the planting layer frame assembly can rotate at a low speed, and the illumination effect is better. In this way, the black nightshade can rotate slowly in the cultivation process, so that all positions can receive illumination; the illumination assembly can move back and forth in the vertical direction, so that the LED light bars on the illumination assembly can move back and forth vertically, after the positions of the LED light bars are adjusted, whether to move back and forth for illumination or not can be selected to increase the illumination area according to the growth condition of the black nightshade, and the requirement for large-area illumination can be met in the later growth period of the black nightshade.

This invention belongs to the field of biomedical materials and relates to a method for preparing a multi-dynamically bonded hydrogel based on polysaccharides from the traditional Chinese medicine *Solanum nigrum* and its application. *Solanum nigrum* is initially extracted and precipitated with alcohol to obtain crude polysaccharides. The polysaccharides are then deproteinized using the Sevag method to obtain a crude polysaccharide solution. After dialysis and freeze-drying, crude polysaccharide is obtained. The crude product is separated and purified to obtain homogeneous polysaccharides. The homogeneous polysaccharide solution is reacted with sodium periodate solution in the dark, followed by dialysis, purification, and freeze-drying to obtain oxidized *Solanum nigrum* polysaccharide OBY. OBY is dissolved in boric acid solution to obtain solution A. Carboxymethyl chitosan is dissolved in polyvinyl alcohol solution to obtain solution B. After the solutions A and B have fully reacted, they are placed in a mold to obtain a multi-dynamically bonded hydrogel based on *Solanum nigrum* polysaccharides. This hydrogel can be applied to the preparation of drugs for chronic wound repair, providing a novel material system and application strategy for developing new wound dressings with excellent physicochemical properties, intelligent response characteristics, and active repair functions.

The invention discloses a traditional Chinese medicine plaster for warming kidney, dredging collaterals and assisting pregnancy and a preparation method thereof, the traditional Chinese medicine plaster for warming kidney, dredging collaterals and assisting pregnancy is composed of the following traditional Chinese medicine components and plaster matrix in parts by weight: the traditional Chinese medicine components comprise 0.5 part of pilose antler, 3.5 parts of eucommia ulmoides, 2 parts of angelica sinensis, 2 parts of solanum nigrum and 2 parts of ligusticum wallichii; the traditional Chinese medicine components are all raw medicine fine powder, or are mixed with the plaster matrix after being fried, and the plaster matrix is a common matrix of a traditional Chinese medicine patch and can bear the traditional Chinese medicine components and realize skin application; the plaster matrix comprises but is not limited to a rubber matrix, a hot melt adhesive matrix and a cataplasm matrix. The traditional Chinese medicine plaster has the advantage of targeted pregnancy assistance, and the use functionality of the traditional Chinese medicine plaster is remarkably improved.

The invention discloses a traditional Chinese medicine formula for adjuvant therapy of esophageal cancer and radiation esophagitis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine formula comprises the following raw materials: sculellaria barbata, hedyotis diffusa, nightshade, reed root, salvia chinensis, concha arcae, radix glehniae, radix actinidiae chinensis, cynanchum paniculatum, lotus leaf, blackberry lily, subprostrate sophora, rabdosia rubescens, scaphium scaphigerum, amomum cardamomum, fructus forsythiae, selfheal and garden balsam. , radix clematidis, radix scrophulariae, salvia miltiorrhiza and oyster. The formula has the effects of clearing away heat and toxic materials, diminishing swelling and removing stasis, nourishing yin and moistening dryness, and activating meridians to stop pain, can effectively relieve choking of esophageal cancer patients and red, swollen and painful throat of radiation esophagitis patients in the radiotherapy period, and improves the life quality and treatment effect of the patients.

The invention discloses a traditional Chinese medicine composition for treating liver cancer and a preparation method thereof, the traditional Chinese medicine composition takes turtle shell as a monarch drug, astragalus membranaceus, curcuma zedoary, oyster and nightshade as ministerial drugs, radix pseudostellariae for tonifying qi and nourishing yin, lucid ganoderma for nourishing qi and blood and enhancing the effect of astragalus membranaceus for tonifying healthy qi, oldenlandia diffusa for clearing away heat and toxic materials, akebia fruit for regulating qi, activating blood and removing stasis, and the traditional Chinese medicine composition has the effects of clearing heat and removing toxicity. The capacities of the monarch drug and the ministerial drug for removing stasis toxin and dissipating abdominal mass are enhanced; raw liquorice is used as a conductant drug for regulating the drug property. The traditional Chinese medicine composition has the effects of soothing the liver, strengthening the spleen, tonifying qi and activating blood for liver cancer patients, and can also soften hard lumps, dissipate stagnation, clear away heat and toxic materials, nourish yin, promote salivation, clear deficiency heat and improve the life quality of the patients. The Chinese herbal medicine composition disclosed by the invention is simple in preparation method, easy to popularize, high in compliance in the aspect of anti-liver cancer use, high in tumor inhibition rate, exact in curative effect and safe in clinical application, and has important significance in treatment of liver cancer.

The invention discloses traditional Chinese medicine granules for treating lung cancer and a preparation method thereof, and relates to the technical field of traditional Chinese medicine formulas. The invention discloses traditional Chinese medicine granules for treating lung cancer. The traditional Chinese medicine composition is prepared from aged black nightshade, marsdenia tenacissima, podophyllum, thunberg fritillary bulb, sculellaria barbata, oldenlandia diffusa, ganoderma applanatum, poria cocos, phellinus igniarius, honeysuckle, fructus forsythiae, dandelion, carbonized sanguisorba root, humifuse euphorbia herb, phyllanthus urinaria, folium isatidis, astragalus membranaceus, cottonrose hibiscus leaves, pericarpium trichosanthis, lance asiabell root, radix ranunculi ternati, spicate clerodendranthus herb, platycodon grandiflorum, aster, rhizoma atractylodis macrocephalae, herba cepbalanoplosis segeti, scorpio, turtle shell, radix ophiopogonis, codonopsis pilosula, radix pseudostellariae, momordica grosvenori, fig, Japanese ardisia herb and pyrrosia lingua. The traditional Chinese medicine has the effects of detoxifying, astringing to stop bleeding, astringing lung and improving symptoms, can finally reduce relapse, and is safe and reliable.

The present application relates to a kind of steroid compound and its application in treating neurodegenerative diseases, the steroid compound has the structure shown in formula I: The steroid compound of structure I is isolated from the whole grass of Solanum nigrum by yeast fermentation for the first time, it shows better neurotrophic factor (NGF) activity and acetylcholinesterase inhibitory activity, is expected to be developed as the drug or functional food of neurotrophic and neuroprotective function, for treating neurodegenerative diseases (such as senile dementia).

The invention provides an extraction method of alpinia katsumadai polysaccharide, which comprises the following steps: S1, taking alpinia katsumadai, crushing, sieving, adding ethanol for degreasing and decolorizing, filtering and drying to obtain alpinia katsumadai powder; s2, water is added into the melastoma dodecandrum powder, heating and repeated extraction are performed, extracted filtrate is combined and concentrated, and a melastoma dodecandrum extracting solution is obtained; s3, adding absolute ethyl alcohol into the solanum melongena extracting solution while stirring, stopping when the ethanol concentration reaches 75%, staying overnight at 4 DEG C, and centrifuging to obtain a polysaccharide crude product; and S4, dissolving the polysaccharide crude product, adding a Sevage reagent, oscillating, centrifuging, removing a lower organic phase and an intermediate protein layer, repeating until no white protein appears in the intermediate layer, and finally dialyzing and freeze-drying a water phase to obtain the melongena melongena polysaccharide. The extracted polysaccharide has good oxidation resistance; furthermore, the polysaccharide is prepared into hydrogel, and the hydrogel has good physical and biological activity and can be used for wound healing. The result provides a theoretical basis for further development and utilization of the alpinia katsumadai.

This invention relates to a plant composition with whitening effects and its application. The whitening plant composition includes extracts of *Scleroderma wilfordii*, *Myrothamnus flabellifolia*, and *Solanum nigrum* root. The whitening plant composition of this invention utilizes the combination of three plant extracts, resulting in a rational formulation where each active ingredient complements the others, synergistically enhancing their effects. This effectively inhibits tyrosinase activity and reduces melanin synthesis, exhibiting significant whitening efficacy. When applied to cosmetics, this plant composition results in stable products that also provide skin repair, reduce the irritation of whitening ingredients, and are suitable for various skin types, fully meeting consumers' demand for natural, gentle, and highly effective whitening products.

The invention relates to application of a traditional Chinese medicine composition in preparation of medicines for preventing or treating colon cancer. The traditional Chinese medicine composition comprises sculellaria barbata, astragalus membranaceus, angelica sinensis, nightshade, radix curcumae, red ginseng, duchesnea indica, saussurea involucrata, cyclea verticillata and salvia miltiorrhiza. The traditional Chinese medicine composition has a good prevention or treatment effect on colon cancer, specifically, proliferation of colon cancer cells is inhibited, a good prevention and treatment effect is shown in a colon cancer mouse model, and the size of mouse tumors can be remarkably reduced. The invention provides an effective strategy for prevention or treatment of colon cancer, and provides a new direction for application of the traditional Chinese medicine composition.

The invention relates to a color-adjustable pigment emulsion as well as a preparation method and application thereof, and provides a pigment extraction method based on high-voltage pulsed electric field and complex microbial inoculant fermentation, which comprises the following steps: respectively taking nigrum fruit and corn meal as substrates, and fermenting by using a complex microbial inoculant consisting of saccharomycetes, fusarium and bacillus cereus, the fermentation liquor is treated by a high-voltage pulsed electric field to efficiently extract solanum nigrum fruit anthocyanin and maize yellow pigment. The core is that the extracted maize yellow pigment and nightshade fruit anthocyanin are prepared into the emulsion. The emulsion has the unique advantage that the emulsion has the intelligent and adjustable color characteristic, and meanwhile, the overall stability of the composite pigment can be remarkably improved. Based on the pH response discoloration characteristic, the emulsion can also be used as an intelligent indicator to be applied to the fields of food fresh-keeping packaging and the like. The invention provides an innovative pigment product which is adjustable in color and high in stability and has nutrition and indication functions, and an efficient and green preparation process of the innovative pigment product.

The invention belongs to the field of medicines, and particularly relates to a preparation method of a steroid compound for treating neurodegenerative diseases, which comprises the following steps: (1) crushing and sterilizing dried black nightshade herb, mixing with dried yeast, placing in a fermentation tank subjected to sterile treatment, adding sterile water, uniformly stirring, sealing, and fermenting at 35-37 DEG C for 24-48 hours to obtain a fermented product; (2) sterilizing the fermented product obtained in the step (1), filtering, collecting filtrate, extracting for 1-3 times by using dichloromethane with the same volume, combining dichloromethane phases, and concentrating to obtain extract; and (3) sequentially carrying out normal-phase silica gel column chromatography separation, Sephadex LH-20 gel column chromatography separation and high performance liquid chromatography separation on the extract obtained in the step (2) to obtain the steroid compound.