The invention discloses a gynecological pill and a preparation method thereof. The gynecological pill is prepared from radix sophorae flavescentis, cortex phellodendri chinensis, rhizoma coptidis, fructus cnidii, fructus forsythiae, herba taraxaci, radix gentianae, catechu, olibanum, myrrha, borneol and sangusis draconis. Formula bulk drugs are porphyrized and disintegrated, and are mixed; afterwards, an appropriate amount of purified water is added into an obtained first mixture; an obtained second mixture is sufficiently mixed and is made into a soft material; a 14-mesh sieve is selected and used for granulation; granules are dried; the granules which are uniform in size are selected and taken, and are put into a coating pan; afterwards, the coating pan is rotated; a small amount of water is sprayed into the coating pan; a small amount of medicinal powder is added into the coating pan; coated pills in required size are made once through repeated operation; subsequently, the coated pills are subjected to low-temperature drying and are selected, so as to obtain the pills. A formula comprising pure natural traditional Chinese medicinal materials is adopted for the gynecological pill; the gynecological pill has the functions of clearing away heat and toxic material, eliminating dampness, killing parasites to relieve itching, activating blood circulation, easing pain, stopping bleeding and promoting tissue regeneration. Further, the dosage form of the gynecological pill is simple; the gynecological pill is enveloped by using absorbent cotton gauze, is convenient to use, and can be used for effectively treating various gynecological inflammations. The preparation method is simple in process, has a low requirement on a device, is environmentally friendly, and is suitable for industrialized enlarged production.