89 results about "Functional change" patented technology

A method and system are provided for determining a condition of a selected region of epithelial tissue. At least two current-passing electrodes are located in contact with a first surface of the selected region of the tissue. A plurality of measuring electrodes are located in contact with the first surface of the selected region of tissue as well. Electropotential and impedance are measured at one or more locations. An agent may be introduced into the region of tissue to enhance electrophysiological characteristics. The condition of the tissue is determined based on the electropotential and impedance profile at different depths of the epithelium, tissue, or organ, together with an estimate of the functional changes in the epithelium due to altered ion transport and electrophysiological properties of the tissue.

Methods and systems are provided for determining a condition of an organ, or epithelial or stromal tissue, for example in the human breast. The methods incorporate sonophoresis, the application of ultrasonic energy, in order to condition tissue for testing and enhance test measurements. A plurality of electrodes are used to measure surface and transepithelial electropotential and impedance of breast tissue at one or more locations and at several frequencies, particularly very low frequencies. An agent may be introduced into the region of tissue to enhance electrophysiological characteristics. Pressure, drugs and other agents can optionally be applied for enhanced diagnosis. Tissue condition is determined based on the electropotential and impedance profile at different depths of the epithelium, stroma, tissue, or organ, together with an estimate of the functional changes in the epithelium due to altered ion transport and electrophysiological properties of the tissue. Devices for practicing the disclosed methods are also provided.

A non-invasive apparatus system for monitoring autonomic nervous system, and its uses in monitoring autonomic nervous system functional change side effects caused by drugs and monitoring the aging of autonomic nervous system and tracing therapeutic effect thereof.

A method and system for analysis of fluorescence emission spectroscopy data and fluorescence lifetime imaging microscopy data are described. A unique Laguerre expansion can be found for fluorescence intensity decays of arbitrary form with convergence to a correct solution faster than with conventional methods. The Laguerre expansion technique includes expansion coefficients highly correlated with intrinsic fluorescence lifetimes, allowing direct characterization of fluorescence dynamics. For complex systems, conventional analysis of fluorescence intensity decay in terms of discrete exponential components can not readily provide a true representation of underlying fluorescence dynamics. Utilizing the Laguerre expansion technique, an alternative non-parametric method for analysis of time-resolved fluorescence data from various systems is described, facilitating characterization and discrimination of a sample. An ultra-fast method for analysis of fluorescence lifetime imaging is also described, facilitating real-time analysis of compositional and functional changes in samples, at a microscopic or macroscopic level.

The invention discloses a software testing method, device and system. The method comprises the following steps: receiving a testing request of a software to be tested; acquiring the information of two different versions of the software to be tested, achieving differential comparison to acquire differential data, building functional change functions of the differential data and saving the functional change functions in a database; retrieving functional application functions of test cases saved in a tagged database; according to the matching between the built function change functions of the differential data and the retrieved functional application functions of the test cases saved in the tagged database, building the corresponding relation between the differential data and the test cases; determining the test cases of the software to be tested; and testing the software to be tested according to the determined test cases. According to the invention, the accuracy and the performability in software testing are improved.

A method and system provides for electrophysiological data analysis in a networked processing environment. The method and system includes receiving, via a networked connection, electrophysiological data of a patient and electronically performing, via at least one network processing device, a data analysis on the electrophysiological data. The method and system includes generating at least one report based on the data analysis, wherein the at least one report includes determination of one or more intervention options for the patient and therein transmitting the report to a recipient device across the network connection for utilization with the patient. The results of the report direct the user to apply from within the same system non-invasive brain stimulation, neurofeedback, and biofeedback modalities. Re-assessment can occur from within the same system following the training or modulation of electrophysiology and thereby generate a comparison report showing functional changes from the provided intervention or combined interventions.

In accordance with embodiments, there are provided techniques for managing functionality changes of an on-demand database system. The techniques facilitate implementing changes to the database system while minimize work flow reductions to users of the database system. To that end, one embodiment of the present invention delays implementation of the changes to provide users of the system an opportunity to adjust behavioral interaction with the database. In accordance with another embodiment of the present invention, users may implement the functional changes to determine any adverse impact on work flow, before the functional changes become permanent. In another embodiment, the user may be afforded an opportunity to selectively enable and disable the functionality changes before the duration expires.

A universal linker structure is provided, in which a functional group and activating leaving group are placed on a tether, allowing the placement of an electrophile at the end of any nucleic acid sequence. The electrophile on the tether can react with a second nucleic acid carrying a nucleophile when the two nucleic acids are hybridized near one another, resulting in release of the leaving group, and creation of a functional change. The linker can be designed to destabilize the ligation product without slowing the rate of reaction. This lowers product inhibition, and the target DNA or RNA can become a catalyst for isothermally generating multiple signals for detection. This enhanced signal is demonstrated in solution experiments and in solid supported assays. The universal linkers of the present invention are simple and inexpensive to prepare, and can be appended to any polynucleotide in automated steps on a standard DNA synthesizer.

A method and system are provided for determining a condition of a selected region of epithelial and stromal tissue in the human breast. A plurality of measuring electrodes are used to measure the tissue and transepithelial electropotential of breast tissue. Surface electropotential and impedance are also measured at one or more locations. An agent may be introduced into the region of tissue to enhance electrophysiological characteristics. The condition of the tissue is determined based on the electropotential and impedance profile at different depths of the epithelium, stroma, tissue, or organ, together with an estimate of the functional changes in the epithelium due to altered ion transport and electrophysiological properties of the tissue. Devices for practicing the disclosed methods are also provided.

Human and mammalian skin undergoes a variety of changes associated with chronological aging. Various environmental factors, disease states and genetic disorders may accelerate both the appearance of aging skin and also the structural and functional changes associated with aging skin. Ultraviolet radiation from the sun is one of the classic known and well-defined means of accelerating or worsening the aging of the skin and this is frequently termed photoaging. Other environmental factors, such as oxidative stress, free radicals, environmental toxins such as ozone and cultural customs or habits such as tobacco smoking are other known probe accelerators in photo aging skin. A wide variety of other factors known and unknown contribute to accelerated or premature aging of the skin. This invention discusses methods where electromagnetic radiation, in particular, light, can be used to photobiomodulate the activity of living cells to delay, diminish, retard or even reverse the structural and functional effects of aging of the skin and other living cells and tissues. In particular methods described for improving the appearance, structure, function of aging skin, including up and down regulating the genotypic markers for the phenotype of aging skin.

The present invention relates to a cardiovascular diagnostic system which enables early detection of cardiovascular diseases and defines their causes. Unlike known electrocardiographs, the cardiovascular diagnosis system can further measure elastic coefficient of blood vessels (the degree of arteriosclerosis), blood vessel compliance, blood flow, and blood flow resistance and velocity in blood vessel branches of the right and left coronary arteries. The elastic coefficient shows organic changes to blood vessels. The compliance shows organic and functional changes of blood vessels simultaneously. The blood flow shows blood flow resistance.

The invention discloses a real-time human body gesture supervised training correction system based on quaternion. The system comprises a depth-indexing video collection device used for collecting the depth image information of a trainee, a human body gesture analyzing and processing module used for analyzing and processing the main joint information of the trainee, an electrocardio information collection device used for collecting and transmitting the electrocardio information of the trainee, and a human body metal state analyzing and processing module used for obtaining the information such as nervous degree, fatigue degree and emotion change of the trainee by analyzing and processing the heart rate, the breathing frequency and the like of the trainee. The real-time human body gesture supervised training correction system based on quaternion can meet the requirements of self training, assistive training and professional teachers on carrying out digitalized correction and supervising on the metal state or functional change of the trainee in real time, and is applicable to all the fields requiring supervised training correction on a human body gesture.

A television (1) of the present invention comprises: a basic function executing section (42) for executing a basic function program called from a control script, the basic function program being stored in a basic function program storage section (29); and a control script executing section (41) for controlling the basic function executing section (42) according to the control script so as to perform first and second functions, the control script defining as the second function, at least a visual effect outputting function for adding a visual effect to an image displayed by the first function, so that the image is displayed with movement; and the control script executing section (41) displaying the image and executing the visual effect outputting function to the image according to the control script. Therefore, it is possible to easily change the functions of the apparatus.

The invention provides a wheeled propeller which comprises an inner supporting ring. An outer buffer base is arranged outside the inner supporting ring, a plurality of propeller blades are arranged inside the inner supporting ring and connected with an engine through a propeller shaft and a coupler. The mode of separating ground running and flying functions can be realized by combining a plurality of devices, the wheeled propeller can be simply implemented by functional change of a single component, so that parts are greatly decreased, production cost is reduced, and product safety is further improved. Appearance with better overall sense can be designed, three-dimensional transport in a city can be continuously extended, city roads and airport construction load can be decreased, land resources are protected, an automobile can be freely switched between the ground mode and a sky mode, and the wheeled propeller can become an excellent army aviation weapon platform and has a certain cargo transportation and regional monitoring capacity.

Methods for measuring transporter activity using budding baculoviruses that do not express endogenous transporters on their envelope have a low background level and can measure the target activity with a high sensitivity. Such methods can be used to measure functional changes due to transporter SNPs over a more extensive range of substrates, and can be applied to tailor-made therapies.

The invention provides a human body endocrine system health risk early warning system, which comprises a human body health scanning system, an endocrine system health risk early warning data processor and an endocrine system health risk early warning result display, wherein the human body health scanning system is used for scanning and evaluating the function values of each tissue and organ of a human body endocrine system; the endocrine system health risk early warning data processor uses a human body endocrine system health risk early warning model for performing human body endocrine system health risk early warning; the output end of the human body health scanning system is connected with the input end of the endocrine system health risk early warning data processor; and the output end of the endocrine system health risk early warning data processor is connected with the endocrine system health risk early warning result display. The organ function of the endocrine system is comprehensively scanned in a short time; the organ function of the endocrine system is evaluated; and the human body tissue energy change and the organ functional change are discovered in time. The potential risk factors and the disease development direction are predicted through combining endocrine system clinical index data, and the health risk of the endocrine system realizes early-stage early warning.