9 results about "Conduction pathway" patented technology

The invention relates to an amplified reactance filter for transducer ultrasound. A reactance filter assembly includes a reactance filter acoustically coupled to a transducer operable to generate an audio frequency by air non-linear demodulation of an ultrasonic frequency, the reactance filter having a plurality of auditory conductive pathways tuned to introduce a radiation impedance to the transducer, therefore, the efficiency of the transducer is improved.

Disclosed herein include methods, compositions, and kits useful for use in the treatment of cancer in a subject. The methods may include administering a PLK1 inhibitor (e.g., onvansertib) to the subject to inhibit a hypoxia signaling pathway in the subject to reduce or inhibit the progression of the cancer.

Systems, devices, and methods for delivering conductive nanomaterials to a target location in a patient's heart to affect the patient's heart conduction system, such as delivering conductive nanomaterials into the ventricular septum of the patient's heart to improve an impaired heart conduction pathway, such as the left bundle branch.

The invention discloses a nasal delivery double-chain RNA / Mn < 2 + > nano-drug as well as a preparation method and application thereof in immunotherapy. And adding the polymer into a solution containing double-stranded RNA and manganese salt, and self-assembling to form the nasal delivery double-stranded RNA / Mn < 2 + > nano-drug. The invention provides a new technical scheme for the barrier of the BBB. The nano delivery system has the advantages in the aspects of overcoming the BBB and improving the in-vivo biological distribution of the drug, and the surface of the nano carrier is modified with a ligand targeted to an endothelial cell overexpression receptor, such as ApoE peptide and the like, so that the drug can be delivered to penetrate through the BBB; a non-invasive nasal-brain delivery strategy becomes a new scheme for improving drug availability and reducing toxic and side effects, the drug can bypass BBB and rapidly enter brain parenchyma through olfactory bulb and trigeminal nerve conduction pathways, and an immune drug delivered by the nasal cavity can rapidly enter nasopharynx-related lymphatic tissue (NALT) and is transferred to CLN through a lymphatic network around the nasal cavity, so that the immune drug can be rapidly delivered to the nasopharynx-related lymphatic tissue (NALT). Further, a potent local immune response aiming at the in-situ GBM is induced.

The invention relates to the field of medical education simulation training, in particular to an analogue simulation method and system for visual conduction path damage, and the method comprises the steps: collecting the positioning data of a student on a model containing a plurality of damage nodes, calculating the stability degree through the comprehensive evaluation of the data volatility and the spatial weight, and calculating the stability degree; screening out effective positioning data; performing dynamic clustering analysis on the effective data, identifying a mistaken touch mode and mapping the mistaken touch mode to a corresponding damaged node; and calculating the misjudgment rate of each node based on the correct identification times and the mistaken touch mode information, thereby identifying the teaching difficulty and adaptively adjusting the training content. Through data reliable processing, false touch mode fine analysis and quantitative feedback closed loop, the problems that an existing teaching tool is low in interaction precision and rough in evaluation are effectively solved, and the data reliability, the error diagnosis precision and the personalized teaching effect of simulation training are remarkably improved.

The present application relates to the field of medical education simulation training, more particularly, the present application relates to a visual conduction pathway injury simulation method and system, the method comprises: collecting the positioning data of students on the model containing multiple injury nodes, calculating the stability degree by comprehensively evaluating the data volatility and spatial weight, and screening out effective positioning data; dynamic clustering analysis is carried out on the effective data, the mis-touch mode is identified and mapped to the corresponding injury node; the misdiagnosis rate of each node is calculated based on the correct identification times and mis-touch mode information, and the teaching difficulties are identified and the training content is adaptively adjusted. The present application solves the problems of low interaction precision and rough evaluation of existing teaching tools through data reliability processing, mis-touch mode fine analysis and quantitative feedback closed loop, and significantly improves the data reliability, error diagnosis accuracy and personalized teaching effect of simulation training.

This invention relates to the field of ocular visual function rehabilitation and neuroelectrophysiological regulation technology. The invention discloses an ocular photostimulation matrix device, comprising: a housing; a display screen, power socket, power switch, and output socket disposed on the housing; a circuit board, a specific medical transformer, and a card reader chip assembly disposed inside the housing; and an output component connected to the output socket. This device is a non-invasive ocular rehabilitation device, breaking through the limitations of traditional vision correction and nerve repair technologies. Using 8-14Hz alpha waves as its core, it directly targets the core link of the visual nerve-central nervous system, fundamentally repairing visual conduction pathway disorders. It is non-invasive, has no usage restrictions, and is suitable for various visually impaired individuals. The device is easy to operate and can be used daily. It can induce endogenous light for preliminary fundus screening and can also address vision repair and brain nerve regulation. Supporting accessories further enhance the conditioning effect and device stability.

The invention discloses a multi-mode pain sense conduction path intelligent interaction demonstration system and a construction method thereof, and relates to the technical field of biomedicine teaching demonstration equipment. In order to solve the defects that an existing pain sense demonstration device is in a static demonstration mode and cannot dynamically restore various pathological features, multi-source commands are prone to preempting conflicts, adaptation is tedious due to hardware parameter hard coding, and cross-scene expansion and maintenance cost is high, a brain region model, a trunk model, a stomach model and a nervous system model are fixed to a human skeleton model; the nervous system model is used for displaying a nerve conduction path so as to simulate a pain transmission path; the interaction module is used for inputting a control signal so as to control the nervous system model to display a corresponding nerve conduction pathway; the driving module is used for receiving a control signal of the interaction module; the driving module is used for displaying a corresponding nerve conduction path; the scheduling module is used for responding to a plurality of scheduling instructions according to a preset priority. The device is mainly used for intelligently demonstrating the multi-mode pain sense conduction pathway.