Activation method and application of compensatory cells

By using a special detection and conditioning pen to accurately locate and activate dysfunctional neural pathways, the shortcomings of existing neurorehabilitation technology in accuracy and non-invasiveness are solved, and rapid and efficient neurological function repair and rehabilitation effects are achieved.

CN120617016APending Publication Date: 2025-09-12李学英
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Patent Information

Application Number
CN202510836953.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-22
Publication Date
2025-09-12

AI Technical Summary

Technical Problem

Existing neurorehabilitation technologies are insufficient in terms of precise intervention, speed of onset and non-invasiveness, especially in treating intractable neurological dysfunctions such as stroke sequelae and Parkinson's disease. Patients suffer from long and painful illnesses and their recovery is incomplete.

Method used

Two special pens without electronic components are used, one is a detection pen and the other is a conditioning pen. The detection pen is used to accurately locate the dysfunctional nerves, and the conditioning pen is used to provide precise and gentle stimulation to activate the compensatory mechanism and repair or awaken the damaged/dormant neural pathways.

Benefits of technology

It achieves non-invasive, painless, precise positioning, fast and efficient nerve function repair, is easy to operate, has quick results, and has no side effects. It is suitable for rehabilitation and health care of multiple systems, is applicable to a wide range of people, and has significant effects.

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Abstract

The invention belongs to the technical field of neural restoration, and discloses a compensatory cell activation method and application, two special pens without electronic elements are used, one pen is a detection pen used for positioning problematic nerves, the other pen is a conditioning pen used for nerve conditioning, and the two pens are used in cooperation; a probe pen is used for searching for nerve reaction points in a specific area of the body surface, malfunctional nerves and nerve roots / neurons of the malfunctional nerves are accurately positioned, a conditioning pen is used for accurately and mildly stimulating the positioned nerve reaction points, signals are conducted with the nerves, a compensation mechanism is activated, and damaged / dormant neural pathways are repaired or awakened; and the normal control ability of the brain on limbs is recovered. The method is noninvasive and painless, accurate in positioning, simple and convenient to operate, easy to learn and operate, rapid and efficient.
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Description

Technical Field

[0001] The present invention belongs to the technical field of nerve repair, and in particular relates to a compensatory cell activation method and application. Background Art

[0002] Traditional neurorehabilitation techniques (such as high drug dependency, severe surgical trauma, slow onset of physical therapy requiring high-intensity training, and rough targeting of conventional electrical stimulation) have significant shortcomings in precise intervention, rapid onset, and non-invasiveness. These are particularly effective for treating intractable neurological dysfunctions (such as dystonia, motor / sensory loss, and unexplained pain) caused by stroke sequelae and Parkinson's disease. Patients often face prolonged illness, severe pain, and incomplete recovery. To address this, the Pore Activation team has proposed a novel concept based on biophysical signal transduction, dedicated to developing a non-invasive and painless technology that can precisely locate and instantly regulate dysfunctional neural pathways. This approach aims to overcome the bottlenecks of existing treatments, achieve rapid repair and reconstruction of neurological function, and address the urgent market demand for efficient, safe, and convenient neurointervention tools. Summary of the Invention

[0003] In order to overcome the above technical problems, the present invention provides a compensatory cell activation method and application.

[0004] The present invention adopts the following technical solutions: A method for activating compensatory cells: Two special pens without electronic components are used. One is a detection pen, which is used to locate the problem nerve, and the other is a conditioning pen, which is used to condition the nerve. The two pens are used together. Use the detection pen to find nerve reaction points in specific areas of the body surface, accurately locate dysfunctional nerves and their nerve roots / neurons, and use the conditioning pen to accurately and gently stimulate the located nerve reaction points to transmit signals to the nerves, activate the compensatory mechanism, repair or awaken damaged / dormant nerve pathways, and restore the brain's normal ability to control the limbs.

[0005] Preferably, the dual pen operation requires minimal force, only the force of writing is required, with the pen tip lightly touching the skin.

[0006] Preferably, the focus is on finding the "starting point" of the "dendrites and axons" on the nerve conduction pathway for intervention.

[0007] Application of the above compensatory cell activation method in the treatment of stroke.

[0008] Application of the above compensatory cell activation method in the treatment of cerebral hemorrhage.

[0009] Application of the above compensatory cell activation method in the treatment of Parkinson's disease.

[0010] Application of the above compensatory cell activation method in the treatment of nervous system damage.

[0011] Compared with the prior art, the present invention has the following beneficial effects: Non-invasive and painless: The operation force is extremely small, only "writing force" is required, the pen tip touches the skin lightly, without breaking the skin, bleeding, no needles, no medicine, and no side effects.

[0012] Precise positioning: The probe pen can accurately locate specific, dysfunctional nerve bundles.

[0013] Easy to operate: the operator only needs to hold the pen to operate, which requires very little physical strength, is easy to learn and operate, and has a wide audience.

[0014] Fast and efficient: fewer operations are required on one point / part.

[0015] Features: 1. Accurately find the pain point and carry out green therapy.

[0016] 2. Safe and painless, with no side effects.

[0017] 3. It works instantly.

[0018] 4. No needles, no medicine, no surgery, no bleeding, no pain 5. Effective for sensory and motor dysfunction.

[0019] 6. It is particularly effective for muscle tension.

[0020] 7. Effective for unknown pain in various parts of the body.

[0021] 8. It can provide rehabilitation and health care for the eight major systems of the human body.

[0022] 9. Activate the nervous system and achieve significant recovery effects.

[0023] 10. First arrange for the current test, accept the case if it works, otherwise reject it. DETAILED DESCRIPTION

[0024] The following embodiments of the present invention are described in detail. Unless otherwise specified, the raw materials and equipment used can be purchased from the market or are commonly used in the art. The following embodiments are exemplary and are only used to explain the present invention, and should not be understood as limiting the present invention.

[0025] Pore ​​Activation 1 Activate compensatory cells 2. Use special techniques and tools to detect abnormal, damaged or dormant autonomic nerves for rehabilitation treatment The brain's compensatory mechanisms are achieved through a variety of mechanisms, including neuroplasticity, functional reorientation, and neural compensation. Neurons, glial cells, and neural stem cells are all involved in this process. While there are no dedicated "compensatory cells" in the brain, these cells work synergistically to enable varying degrees of recovery after damage, providing a key theoretical basis for rehabilitation treatment of stroke sequelae.

[0026] It is also the theoretical basis for the development and research of pore activation technology. (one) 1. "Compensatory cells" refer to cells that remain after certain cells in an organism are damaged, die, or experience functional impairments, and can maintain tissue integrity and functional integrity by increasing, strengthening, and dividing to a certain number. Some cells achieve compensatory functions by increasing in size rather than in number. Others can compensate for the damaged cells by altering their functional state. For example, if certain neurons in the nervous system are damaged, other healthy neurons can replace the damaged neurons by altering synaptic connections and enhancing neurotransmitter release. In simple terms, the human body contains a variety of cells, each responsible for carrying out and maintaining normal body function. If, under certain circumstances, some cells become diseased—for example, due to injury, aging, or death—otherwise, other cells in the body step in to take over or share their original work. This is the role of compensatory cells. For example, when certain organs, such as the heart, liver, and kidneys, or brain cells and nerve cells, become damaged, injured, or die, some cells emerge to complete their normal functions.

[0028] These compensatory cells are not a strictly defined cell type, but rather a functional or behavioral characteristic of a cell under specific physiological or pathological conditions. This compensatory function is an important mechanism for the organism to maintain normal function. 2. Compensatory cells are of great importance in both physiology and pathology: their inherent compensatory mechanisms effectively address the natural aging, damage, and death of cells, ensuring the normal physiological function of the organism. For example, after partial damage to the liver or kidney, the remaining cells can maintain normal function through compensatory hypertrophy and enhanced function, and can also delay the onset and progression of disease to a certain extent.

[0029] (2) Detailed analysis of the relationship between the brain's compensatory mechanism and the nervous system The brain's compensatory mechanisms are implemented through multiple cell types and different mechanisms.

[0030] The following are important components of the brain's compensatory mechanisms: 1. Synaptic connections between neurons can change the efficiency of information transmission by strengthening or weakening. For example, some patients with cerebral infarction experience a transition from slowed thinking to sharp thinking during their recovery. This is due to the plasticity of synapses.

[0031] 2. Neuronal morphology and number can also change. For example, in some cases, the dendrites and axons of neurons can grow new branches to establish new connections. In the aftermath of a stroke, fingers can become paralyzed and unable to care for themselves, but later recover to the ability to flex, bend, and grasp normally. This is due to the plasticity of neural structures.

[0032] 3. When a part of the brain is damaged, other healthy brain areas can take over the functions of the damaged part. For example, if the visual cortex is damaged, the auditory cortex may expand its range of functions to compensate for the loss of visual function. This is because the function of nerves can be relocated, which is an important part of the brain's compensatory mechanism.

[0033] 4. In the event of brain injury or disease, unaffected brain areas can adjust their activity to maintain normal brain function. For example, in Parkinson's disease or the sequelae of cerebral infarction, neurological tremors can be stabilized and then recovered after specific stimulation. This is because the reduction in dopaminergic neurons causes other types of neurons to increase activity, compensating for the loss of dopaminergic neurons. This is a neural compensatory mechanism.

[0034] The cells of the brain's compensatory mechanism are composed of neurons, glial cells, and neural stem cells.

[0035] 1. Neurons, the brain's primary functional cells, compensate by changing their synaptic connections and activity levels. For example, after a stroke, neurons surrounding the damaged area can compensate for the damaged neurons by increasing their activity.

[0036] 2. Glial cells: Microglia: Microglia are the brain's immune cells that can clear dead neurons after brain injury and release neurotrophic factors to promote neuronal survival and functional recovery.

[0037] Astrocytes: Astrocytes regulate neuronal metabolism and ion balance, providing support for neurons. After injury, astrocytes can undergo reactive proliferation, helping to maintain the stability of the neural microenvironment.

[0038] 3. Neural stem cells: There are a small number of neural stem cells in the brain that can differentiate into new neurons under certain circumstances and participate in functional recovery.

[0039] 3. Clinical significance of brain compensatory mechanisms 1. Rehabilitation treatment: The brain's compensatory mechanisms are the foundation of rehabilitation therapy. Long-term rehabilitation exercises can stimulate neuroplasticity and functional reorientation in the brain, helping patients recover impaired functions. For example, rehabilitation training can help stroke patients reestablish neural circuits and restore some motor and sensory functions.

[0040] 2. Disease recovery: By regulating neuroplasticity and neural compensatory mechanisms, the progression of neurodegenerative diseases (Parkinson's disease or limb tremors) can be delayed.

[0041] In summary: If pore activation is performed early and promptly in pathological conditions, normal neuronal connections can increase at an astonishing rate. For example, after nerve impulses to a stroke patient's finger are suppressed, within months or years, the brain region previously responsive to that finger begins to respond to sensory signals from other surrounding fingers, ultimately restoring motor and sensory function. This also reflects compensatory changes in neuronal connections in the nervous system.

[0042] After a nervous system injury, stimulating, activating, and awakening other normal brain cells in the same area on the same side of the brain allows them to compensate for the damage, replacing the damaged cells and continuing to maintain body function. However, this compensatory function requires continuous stimulation and training in the early stages, as new cells must learn to achieve more sophisticated and complete compensation. For example, stroke patients, with minimal muscle tone, can gradually recover to varying degrees through pore activation, which can accurately activate the compensatory function.

[0043] Pore ​​Activation Technology Features: 1. Accurately find the pain points and implement green therapy.

[0044] 2. Safe and painless, with no side effects.

[0045] 3. The effect can be observed immediately after the operation.

[0046] 4. This technology does not require the use of needles or drugs, does not involve surgical operations, and is non-invasive and painless.

[0047] 5. It has an improving effect on sensory and motor dysfunction.

[0048] 6. It has a targeted effect on the problem of increased muscle tension.

[0049] 7. It has an improving effect on various unexplained pains.

[0050] 8. Can be applied to the rehabilitation and conditioning of multiple systems of the human body.

[0051] 9. Activate the nervous system and achieve significant recovery effects.

[0052] Clinical validation Through clinical practice, this technology has been applied to thousands of patients, including those suffering from stroke, cerebral hemorrhage, Parkinson's disease, various motor system injuries, and neurological injuries, achieving an immediate improvement rate exceeding 91%. Patient feedback indicates that this technology is more acceptable and effective than other rehabilitation techniques and procedures, allowing patients to achieve recovery without pain, in a shorter time, and with a faster recovery rate.

[0053] Technical Tools The technology uses only two pens, each with a different function. The materials used have been specially processed and treated. These pens lack any electronic switches, are not equipped with electrodes, and do not generate current.

[0054] Tool function and operation The two pens function as a probe and a conditioning device. They must be used in conjunction with each other; using either pen alone will not produce the desired effect. Operation is simple: simply hold the pen with the same firmness you'd use writing. Each pen has unique effects on multiple systems, particularly the nervous system.

[0055] Mechanism of action As we all know, when the motor system moves, signals are first transmitted through the motor and sensory nerves of the nervous system, which then transmit them to the brain. The brain then controls these signals, inducing limb movement. This technology is very effective for detecting the nervous system. For example, pain in a specific area, such as muscle pain, can occur at different depths and layers. Pain signals from each muscle are transmitted by nerves. These nerve-transmitted signals convey information such as soreness, numbness, or swelling in that area, indicating the specific problem and its cause. This feedback can be used to locate the corresponding nerves and neurons. Neurons receive reflex control from the brain through their conduction pathways.

[0056] For example, detection can be performed from the hand, or through a nerve in the head, foot, or back, directly reaching the brain and activating metabolic cells. Only when metabolic cells are functioning sufficiently can the arm and other parts of the body naturally regain some function. This recovery is extremely rapid, with some patients experiencing results after a single procedure, and others able to significantly perform previously incapable movements after two or three procedures. This rapidity is the foundation for truly achieving immediate results within the first procedure.

[0057] Service Model The patient is first given a treatment and the results are observed. If the results are noticeable, the physical sensations improve significantly, and the patient is very receptive to the treatment, then treatment can continue. The advantage of this method is that it is painless. When using the pen, the patient feels as if the pen is just touching the skin, not piercing it, causing no bleeding. It simply feels like contact with the skin.

[0058] Importance of core tools This pen is crucial for neurological conditioning; without it, the treatments are impossible. This pen acts as a "dialogue" with the nerves. By using the reaction points, the user can determine which nerve is experiencing a problem, whether it's a motor nerve or a sensory nerve. It can pinpoint the problem nerve and initiate rehabilitation through nerve conduction.

[0059] Ease of operation and applicable population This pen is extremely simple to operate, requiring only the strength to grip the pen. It is suitable for a wide range of audiences, including those in their sixties and seventies. Even those with limited physical strength and lacking the necessary strength for massage can master the technique. This technique is highly applicable and widely accessible.

[0060] Effect Example For example, a patient may be unable to lift their arm, or pain prevents them from doing so, making many movements impossible or even affecting their work. A single treatment can yield a 60% to 80% improvement, a remarkable result. The improvement in physical sensation and movement completion rate is particularly rapid and noticeable, making it highly acceptable to patients. Many people, during treatment, want to see the results before deciding whether to continue. We meet this need: we perform the treatment first, allowing patients to see the results. Seeing results indicates that the method is correct. The decision to continue treatment can then be made based on the results. If the treatment is effective by more than 60%, the patient can be clearly informed of the reasons and the expected results within the expected timeframe.

[0061] Detailed case report of increased muscle tone after stroke Take stroke patients as an example. For patients with limited mobility, such as the inability to lift, stretch, or move forward or backward, treatment plans are relatively simple, including the management of pain in a specific muscle. Now, we will focus on cases targeting specific treatment targets: patients with sequelae of cerebral infarction, cerebral hemorrhage, or cerebral thrombosis, particularly those with significantly increased muscle tone.

[0062] Patients assume specific postures (such as flexion spasms), but their bodies actually resist extension with a force of up to 20 kg. This leads to extreme fatigue. Using forceful massage, strong stimulation, forced straightening, strong downward pressure, or other manipulation techniques only leads to increased muscle tension. The more you try to stretch the muscle, the stronger the resistance, making it very difficult to handle.

[0063] Some patients even maintain this abnormal posture for long periods of time (years or even decades). So why is there muscle tone? This indicates that the relevant nerve function is still present. If this function were completely lost, the limb would completely limp and hang down, without any sensation. The presence of a retracting force indicates that motor nerve function is still present. The key is to restore the ability to control limb movement, particularly opening (extension). This requires identifying the nerve responsible for "opening" (inhibiting flexors and promoting extensors).

[0064] The pen is used to probe the hand or the palm. When the target nerve is located, the nerve will respond (such as local tremors) or produce a special electrical conduction sensation.

[0065] Through this sensation, the nerve roots are located. The nerve roots and neurons transmit signals to the brain's command center and issue instructions. The muscles can be loosened immediately. The root of the problem is not muscle weakness, but the loss of control ability. This signal is transmitted to the brain, allowing the brain to re-control. Even limbs that have been spastic for a year, half a year or longer can be opened. This is summarized through a lot of practical experience. The patient must feel the effect firsthand. For example, some patients clench their five fingers. After conditioning, it is found that a specific nerve has a control disorder. The operator searches for its dendrites and axons along the nerve for detection and conditioning. During the conditioning process, the area controlled by the nerve can be stretched, and other nerves can also achieve similar effects after treatment.

[0066] It is intended that the scope of the invention be defined by the following claims and their equivalents.

Claims

1. A method for activating compensatory cells, characterized in that: Two special pens without electronic components are used. One is a detection pen, which is used to locate the problem nerve, and the other is a conditioning pen, which is used to condition the nerve. The two pens are used together. Use the detection pen to find nerve reaction points in specific areas of the body surface, accurately locate dysfunctional nerves and their nerve roots / neurons, and use the conditioning pen to accurately and gently stimulate the located nerve reaction points to transmit signals to the nerves, activate the compensatory mechanism, repair or awaken damaged / dormant nerve pathways, and restore the brain's normal ability to control the limbs.

2. A compensatory cell activation method according to claim 1, characterized in that: The dual pens require minimal force to operate, just the force of writing, with the pen tips lightly touching the skin.

3. A compensatory cell activation method according to claim 1, characterized in that: The key is to find the "starting point" of the "dendrites and axons" on the nerve conduction pathway for intervention.

4. Use of the compensatory cell activation method according to any one of claims 1 to 3 in the treatment of stroke.

5. Use of the compensatory cell activation method according to any one of claims 1 to 3 in the treatment of cerebral hemorrhage.

6. Use of the compensatory cell activation method according to any one of claims 1 to 3 in the treatment of Parkinson's disease.

7. Use of the compensatory cell activation method according to any one of claims 1 to 3 in the treatment of nervous system damage.