73 results about "Tympanic Membranes" patented technology

An earphone comprises a rear feedback microphone, an earmuff front shell and a sound outlet nozzle, an accommodating groove of the earmuff front shell is communicated with the sound outlet nozzle, the accommodating groove accommodates a first loudspeaker and a second loudspeaker, and the front feedback microphone, the first loudspeaker and the second loudspeaker are arranged in sequence. The rear feedback microphone is arranged at the sound outlet nozzle so as to be close to the tympanic membrane of the earphone wearer as much as possible, the sound collected by the rear feedback microphone is closer to the sound heard by the earphone wearer, and the earphone can adjust the anti-phase environmental noise in real time according to the sound collected by the rear feedback microphone; the first loudspeaker is arranged between the sound outlet nozzle and the second loudspeaker, compared with the second loudspeaker, the phase deviation of the anti-phase environment noise emitted by the first loudspeaker transmitted to the eardrum of an earphone wearer is smaller, and when the first loudspeaker and the second loudspeaker participate in active noise reduction at the same time, the phase deviation of the anti-phase environment noise transmitted to the eardrum of the earphone wearer is smaller. The anti-phase environment noise generated by the first loudspeaker can compensate for the phase deviation of the anti-phase environment noise generated by the second loudspeaker propagating to the tympanic membrane.

The invention relates to the technical field of medical data monitoring and early warning, in particular to a dynamic monitoring and early warning system for abnormal function of Eustachian tube. The system is characterized in that a data acquisition module acquires time sequence data of various eustachian tube state parameters such as tympanic chamber vibration, pharyngeal vibration and tympanic chamber air pressure, when a human body is yawn or swallowed, the eustachian tube is opened, the larger the opening is, the stronger the vibration of the tympanic membrane and the pharyngeal is, and the transmission decibel to an external auditory canal is increased, so that a eustachian tube opening section positioning module analyzes the characteristics to determine the auditory canal opening section; the opening amplitude of the Eustachian tube is accurately obtained, and an opening section is accurately cut out; after the Eustachian tube is opened, the air pressure in the tympanic chamber approaches and tends to the external auditory canal air pressure, the health index analysis module divides an approaching section and a leveling section in an opening section based on the air pressure change consistency, analyzes the air pressure change correlation by fusing multi-aspect information, and obtains health indexes by combining section length difference and air pressure difference characteristics; and finally, monitoring and early warning are performed on the Eustachian tube of the monitored object based on the health indexes in a monitoring and early warning module.

The invention relates to the technical field of pronunciation control, and provides a non-contact Hall drumhead vibration sensing and intelligent pronunciation control method and system, and the method comprises the steps: collecting an original Hall sensing electric signal generated when a user knocks a drumhead through a Hall sensor array in a drumhead, carrying out the signal preprocessing of the original Hall sensing electric signal, and obtaining a pre-processed signal; a standard Hall sensing electric signal is obtained, physical characteristic parameters are extracted, and a first tympanic membrane tension parameter, a damping coefficient and a striking position are obtained; obtaining an initial tympanic membrane tension parameter through a tympanic membrane stress sensor, carrying out the comparative analysis of the first tympanic membrane tension parameter and the initial tympanic membrane tension parameter, obtaining a tension decay value, and obtaining a pitch parameter based on a pre-constructed tension decay value-pitch mapping relation. According to the invention, through signal preprocessing and physical characteristic parameter extraction, key quantities reflecting the physical state of the tympanic membrane, such as a tympanic membrane tension parameter, a damping coefficient and a striking position, are systematically extracted, and a real and accurate physical basis is provided for sound generation.

Wearable devices capable of measuring a core body temperature and other vital signs of a user in a range of situations are described herein. The wearable device is arranged to be retained within the ear canal of the ear, in order to prevent the wearable device from inadvertently removing itself from the ear. Providing an infrared thermopile at the innermost end of the ear insert ensures that the infrared thermopile is provided as close as possible to the tympanic membrane which will be used to provide an indication of the core body temperature.

The utility model discloses a tympanic membrane structure for a connecting rod fan, which comprises a tympanic membrane, a circular seal is arranged at the center of the tympanic membrane, and a horizontal limiting structure is arranged at the edge of the circular seal; a sealing pressing plate is assembled on the circular seal, a circular sealing groove is formed in the sealing pressing plate, the circular sealing groove is matched with the circular seal in the center of the tympanic membrane, and a limiting hole for containing the horizontal limiting structure is formed in the circular sealing groove. Through the arrangement of the horizontal limiting structure and the limiting hole which are matched with each other, mutual limiting between the tympanic membrane and the sealing pressing plate is completed, and the situation of air leakage caused by a torsion gap generated between the tympanic membrane and the sealing pressing plate in the working process is prevented.

Disclosed herein is a device for modeling properties of an ear. The device includes an artificial tympanic membrane and a housing coupled to the artificial tympanic membrane. The housing defines an interior portion coupled to an interior surface of the artificial tympanic membrane. The interior portion has an adjustable volume or an adjustable type of fluid and an adjustable gas pressure. Adjustment of the volume or type of fluid and the gas pressure changes a membrane movement to produce selected movement properties according to a mobility scale.

The utility model discloses a novel anti-drop ear ventilation pipe, which comprises a pipe body with an external auditory canal end and a tympanic chamber end, a through channel is arranged in the pipe body, the inner side wall of the pipe body axially extends towards the tympanic chamber end to form a bending part, and when the tympanic chamber end of the pipe body is implanted into a tympanic membrane, the tympanic membrane is inserted into the tympanic chamber end of the pipe body. And the bending part can be bent towards the periphery of the tube body so as to enlarge the contact surface with the inner side of the tympanic membrane. The ventilation pipe can be better fixed to the tympanic membrane after the bending part with the extension bending performance is expanded and unfolded, the ventilation pipe is effectively prevented from falling off, the surface of the pipe body is provided with the silver ion coating with the antibacterial characteristic, the antibacterial effect is achieved, the pipe body is provided with the cutting edge, the tympanic membrane can be cut open conveniently, the ventilation pipe is arranged, and the ventilation pipe is convenient to use. And the use experience of the user can be better improved.

Embodiments are directed to an electronic device configured to measure temperature from within an ear canal having a first bend, a second bend, and a tympanic membrane. The device comprises an enclosure comprising an in-canal section dimensioned for deployment in the ear canal. The in-canal section comprises a trough extending axially along at least a portion of the in-canal section and arranged to be positioned between the first bend and the tympanic membrane when the in-canal section is fully deployed in the ear canal. A temperature sensor is disposed in the trough. The temperature sensor comprises a flexible circuit board, a distal temperature sensor disposed on the flexible circuit board, and a proximal temperature sensor disposed on the flexible circuit board and situated proximal of, and spaced apart from, the distal temperature sensor in an outer ear direction.

The utility model relates to the technical field of medical instruments, and provides an ossicular prosthesis for tympanic sclerosis, comprising: an abutting disc for abutting against the tympanic membrane of a patient; one end of the connecting column is connected with the abutting disc, the other end of the connecting column is provided with a safety limiting piece, the end, away from the abutting disc, of the connecting column is used for being inserted into the inner ear vestibule of the patient, and the safety limiting piece is used for limiting the depth of the portion, inserted into the inner ear vestibule of the patient, of the connecting column; wherein the connecting column is provided with at least one winding ring, and the winding ring is used for adjusting the length of the connecting column. In the process of installing the ossicular prosthesis, when the connecting column needs to be lengthened, a doctor can clamp the winding ring through a clamp so that the two ends of the connecting column can be lengthened; when the connecting column needs to be shortened, a doctor can expand the winding ring with a tool to shorten the two ends of the winding ring. Therefore, the technical effect of quickly and conveniently adjusting the length of the connecting column is achieved. The ossicular prosthesis is more adaptive to the in-ear environment of a patient, and the operation efficiency of a doctor is improved.

The application discloses a tympanic ventilation tube with spiral locking, multiple waterproof and valve control drainage functions, and belongs to the field of ear implant medical devices. The ventilation tube comprises a tube body, an implant device interface is arranged at the outermost end of the tube body, a one-way duckbill valve is arranged at the end close to the external auditory canal, micro-flow ventilation holes are distributed in the circumferential direction of the side wall, a flexible sealing sheet is arranged on the outer side of the tube body, and a continuous single-ring gradually-changing asymmetric spiral fixing structure is arranged on the outer periphery of the middle ear cavity. The spiral fixing structure induces the radial flanging of the tympanic membrane tissue to be embedded between the spiral structure and the outer wall of the tube body to form axial locking through the asymmetric section, and realizes gradual release when reversely rotating through the rise angle, tooth height and round angle gradient; the sealing sheet realizes stable adhesion and controllable peeling through the thickness gradient, pre-stress and surface energy gradient; the micro-flow ventilation holes and the duckbill valve constitute a gas-liquid separation double channel, realize low-resistance ventilation, liquid blocking and pressure-driven drainage. The application can realize stable fixation, water-tight sealing, controllable ventilation, one-way drainage and low-damage implantation and removal.

The application discloses a weak sound amplification device in the field of sound amplification technology, which comprises a base, a controller, a sealed shell and a carrier table; the controller is electrically connected with a signal component, a sound component and a power amplifier, and the power amplifier is electrically connected with a loudspeaker; the sound component comprises a bionic sound channel, the bionic sound channel is fixed with a tympanic membrane at the tail end, the tympanic membrane is attached to the left end of an auditory ossicular chain, and the auditory ossicular chain is hung on an auditory ossicular chain beam; the signal component comprises a manual workbench, a precision workbench and a piezoelectric stack support, the piezoelectric stack support is internally provided with a piezoelectric stack, the front end surface of the piezoelectric stack support is fixedly connected with the rear end of a probe support, and the front end of the probe support is provided with a conductive probe; the auditory ossicular chain and the auditory ossicular chain beam are made of conductive material and are electrically connected; the manual workbench, the precision workbench and the piezoelectric stack are used for adjusting the distance between the front end of the conductive probe and the right end of the auditory ossicular chain in three stages, so that the two are connected with the controller in series to form a closed quantum tunneling circuit. The application solves the problem of difficult weak sound collection.

The invention provides a tympanic membrane puncture positioning method and system based on a clinical image, and relates to the technical field of tympanic membrane puncture localization. The tympanic membrane puncture positioning method comprises the steps that a layered image of a target ear and a tympanic membrane clinical image are collected, and tympanic membrane edge contour data are extracted from the layered image; identifying a light cone vertex and an umbilical region from the clinical image as a first reference point, and setting at least three non-collinear auxiliary positioning mark points on the auricular conchae body surface as second reference points; then, a puncture target point is determined based on the edge contour data and the first reference point, the second reference point and the puncture target point are connected to construct a triangular cone model, and finally, the needle inserting angle and the puncture depth are calculated based on the model by adopting a space geometric positioning method so as to control optical guiding equipment to indicate a puncture path. Puncture parameters can be accurately calculated and a path can be guided through image analysis and cooperation of double reference points and a triangular cone model, and accurate positioning of a tympanic membrane puncture target spot is achieved.

The present application relates to a composition using an endothelin B receptor agonist, such as Sovastatin (N-succinyl-[Glu9, Ala11, 15] endothelin 1, IRL-1620), for promoting cell proliferation and protecting the original neuroepithelium of cochlear and vestibular cells located within the ear sac. The pharmaceutical composition is systemically administered by means of tympanic membrane puncture, cochleostomy or intravenous or intramuscular injection. A pharmaceutical composition for the treatment of sensorineural hearing loss and vestibular disorders caused by inner ear cell degeneration, the pharmaceutical composition comprising a compound of an endothelin analogue, the use being treated by the neuroprotection and neurogenesis mechanism of cochlear vestibular hair cells and synapses.

Embodiments are directed to an electronic device configured to measure temperature from within an ear canal having a first bend, a second bend, and a tympanic membrane. The device comprises an enclosure comprising an in-canal section dimensioned for deployment in the ear canal. The in-canal section comprises a trough extending axially along at least a portion of the in-canal section and arranged to be positioned between the first bend and the tympanic membrane when the in-canal section is fully deployed in the ear canal. A temperature sensor is disposed in the trough. The temperature sensor comprises a flexible circuit board, a distal temperature sensor disposed on the flexible circuit board, and a proximal temperature sensor disposed on the flexible circuit board and situated proximal of, and spaced apart from, the distal temperature sensor in an outer ear direction.

The invention relates to a combined auditory ossicle prosthesis. The combined auditory ossicle prosthesis comprises a top disc and a connecting rod, the top disc comprises a fixed disc and a detachable outer ring which is detachably connected with the outer ring of the fixed disc; the lower surface of the top disc is provided with a connecting seat assembly extending downwards from the center, and the connecting seat assembly comprises a connecting hole penetrating in the axial direction. The connecting rod is an elastic rod body formed by sequentially and alternately connecting first unit sections and second unit sections with the outer diameters changing alternately in the axial direction. And one end of the connecting rod is detachably connected with the connecting seat assembly through the connecting hole, and can axially move in the connecting hole to adjust the insertion depth. The diameter of the top disc of the prosthesis is adjustable, the length of the connecting rod is graded and adjustable, partial / all replacement operations are interchangeable, a single product covers the requirements of multiple specifications, an operator can accurately and finely adjust according to the requirements in an operation, perfect connection of the prosthesis with a stapedius base plate and a tympanic membrane is achieved, optimal sound transmission mechanical coupling is achieved, and the problems that selection is difficult and models are not matched are fundamentally solved.

Aspects of the present disclosure provide a system for preventing or treating tympanostomy tube infections. The system includes an ear tube that is configured to be placed within an ear of a subject. The ear tube has a shaft that extends from a proximal end to a distal end, and a lumen extends through the shaft. The ear tube also includes a flange extending from the shaft at the proximal end and a flange extending from the shaft at the distal end. The system further includes an optical waveguide that is configured to deliver antimicrobial light to a surface area of the ear tube while placed within the ear of the subject. The optical waveguide includes an optical fiber that is configured to deliver the antimicrobial light and a fiber collimator that is configured to guide the antimicrobial light towards the surface area of the ear tube.

The invention belongs to the technical field of biological medicines, and discloses an application of rhizoma acori graminei essential oil in preparation of drugs for preventing and treating sensorineural deafness, the rhizoma acori graminei essential oil is taken as a core effective component, key active substances of the rhizoma acori graminei essential oil are determined to be beta-asarone and isomethyleugenol, and the rhizoma acori graminei essential oil can be prepared into oral preparations and / or ear drops; animal experiments and human body safety tests prove that the rhizoma acori graminei essential oil can remarkably reduce noise-induced hearing threshold displacement, protect the integrity of cochlea outer hair cells and the banding synaptic function of inner hair cells and inhibit cochlea local inflammation pathway activation, and is non-toxic to main organs and free of skin and tympanic membrane irritation. The invention solves the technical problems of poor compliance, obvious side effects on the whole body and indefinite effective components of the existing sensorineural deafness prevention and treatment medicines, and provides a safe and effective prevention and treatment scheme with strong scene adaptability.

The invention relates to the technical field of biological medicine, in particular to liposome dispersion liquid and ear drops capable of penetrating through tympanic membrane and inner ear round window membrane. The invention designs the liposome dispersion liquid which can effectively penetrate through a complete path of the tympanic membrane and the round window membrane of the inner ear after being dripped into the ear through the external auditory canal in a non-invasive manner, so that tympanic membrane perforation caused by injection in a tympanic chamber can be avoided, and the pain and discomfort of a patient can be relieved. The liposome dispersion liquid disclosed by the invention is good in stability, and the prepared ear drops can realize efficient delivery of targeted inner ear medicines, have the characteristics of noninvasiveness and convenience, and have a wide application prospect in the medical field.

A drug delivery system for intratympanic injection, including an intratympanic drug delivery device, including a body having a first end with a first opening and a second end with a second opening, the body being an elongated housing having a hollow chamber running along a length of the body from the first opening to the second opening, the first opening of the body configured to be inserted through a tympanic membrane; and a catheter configured to be inserted through the hollow chamber of the elongated housing of the body of the intratympanic drug delivery device.

The application discloses an inner ear micro-invasion operation robot system and a control method, relates to the technical field of medical devices and operation robots, and discloses an execution system as an operation robot body, which is used for completing an operation operation through an external auditory canal approach under the constraint of a narrow and curved cavity; a guide system is based on preoperative and intraoperative multi-modal images, and is used for providing functions of preoperative approach planning, intraoperative navigation positioning, anatomical structure identification and enhanced visual guidance; a control system is used for receiving and processing operator input and execution and guide system feedback information, realizing data interaction and instruction issuing between a user layer, a control layer and an execution layer, so as to guarantee the precision and stability of robot operation. The application is used to solve the problems that in the prior art, a complete intraoperative navigation system and a systematic operation operation process are lacked, the intelligent degree is limited, the experience of an operator is highly dependent, and a corresponding control system is not perfect; meanwhile, key links such as a tympanic membrane puncture need to be separately completed by using additional instruments, and the robot system is not yet connected.

The invention relates to the field of animal models, in particular to a method for constructing a chronic tympanic membrane perforation rat model. The construction method comprises the following steps: under a microscope, perforating a rear quadrant of a tympanic membrane of a unilateral ear of a rat, embedding a gelatin sponge into the perforated part for a period of time, and then removing the gelatin sponge to obtain a chronic tympanic membrane perforated rat model; wherein the gelatin sponge is a gelatin sponge infiltrated with a drug solution, and the drug solution is a dexamethasone solution. According to the construction method of the chronic tympanic membrane perforation rat model, the success rate of modeling can be increased on the basis of reducing the death rate of animals, animal waste caused by drug toxicity and the risk of cancerogenic substance exposure of experimenters are reduced, and the construction method has important significance in tympanic membrane perforation research.

Systems and methods can be employed to access the middle ear through the tympanic membrane for the delivery of therapeutic agents to, for example, the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otologic procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair, and ossicular chain repair.

The utility model relates to the technical field of medical equipment, and discloses a head end bendable circulating negative pressure flushing sheath which comprises a negative pressure flushing sheath body, an elastic guide head is arranged on the inner wall of the negative pressure flushing sheath body, a circular groove is formed in the outer wall of the negative pressure flushing sheath body, a connecting pipe is fixedly assembled on the inner wall of the circular groove, and the connecting pipe is connected with the elastic guide head. A moving groove is formed in the outer wall of the end, away from the negative-pressure flushing sheath body, of the connecting pipe. When an operation is carried out on a patient, the negative pressure flushing sheath is conveyed from the urethra to the inside of the kidney, so that when calculi in the patient are smashed and sucked out, when water is conveyed from the inner wall of the negative pressure flushing sheath to the kidney and is conveyed from the inner wall of the circular groove to the inner wall of the air outlet pipe, pressure is applied to the tympanic membrane through the flowing pressure of the water; and the tympanic membrane is expanded to extrude air in the air outlet pipe, so that the air in the air outlet pipe is discharged from the air outlet of the air outlet pipe, and meanwhile, the crushed calculus is adsorbed to prevent the calculus from falling into the kidney again.

The embodiment of the application discloses an otological image intelligent identification method based on a multi-modal artificial intelligence, and comprises the following steps: acquiring an otological image and clinical text information of a patient; fusing the otological image and the clinical text information to obtain multi-modal features; and identifying the multi-modal clinical text information features by using a multi-model integrated architecture to automatically determine the tympanic membrane state of the patient, wherein the tympanic membrane state comprises a normal tympanic membrane, a perforation, an inward protrusion, an effusion, a suppurative otitis media, calcification and otosclerosis. The embodiment realizes automatic intelligent identification of the tympanic membrane state.

The invention relates to the field of medical application of biological hydrogel, in particular to dexamethasone loaded hydrogel delivered across tympanic membranes and a preparation method of the dexamethasone loaded hydrogel, the hydrogel takes gelatin Gel and dopamine modified hyaluronic acid HADA as base materials, a three-dimensional network structure is formed through enzymatic crosslinking of transglutaminase mTGase, dexamethasone sodium phosphate Dex is loaded, and the hydrogel can be used for preparing the dexamethasone loaded hydrogel. Furthermore, local trans-tympanic membrane middle ear drug delivery and release are realized; specifically, a solution A composed of Gel, HADA and Dex and a solution B composed of mTGase are evenly mixed according to the volume ratio of 4: 1 and dropwise added to the surface of the tympanic membrane through an external auditory canal, and finally Gel-HADA-Dex hydrogel is formed on the surface of the tympanic membrane. Local precise high-concentration drug delivery can be achieved, systemic drug toxicity is avoided, materials are safe, ear toxicity is avoided, meanwhile, adhesion performance is high, drug release is continuous, gradual self-degradation is achieved, manual taking out is not needed, and use convenience is remarkably improved.

An ultrasonic transducer can include a plurality of capacitive ultrasonic transducer elements and a base having a maximum dimension sized and shaped to be disposed within an external ear canal, wherein the plurality of capacitive ultrasonic transducer elements are mounted on the base. Each capacitive ultrasonic transducer element and the ultrasonic transducer are specifically constructed to achieve selected desired performance characteristics. The ultrasonic transducer can have an angular beam that propagates through a gaseous medium that is greater than 15 degrees and an attenuation loss through the gaseous medium that is greater than 10 dB measured at a distance of 12.5 mm to 25 mm along a primary transmission axis of the ultrasonic transducer. The ultrasonic transducer can be particularly useful for characterizing fluid behind a tympanic membrane to diagnose otitis media.

The present application relates to the technical field of electromagnetic pilot valve, especially to a mine electromagnetic pilot valve protection structure, which comprises a valve body, a medium flow cavity group is arranged in the valve body, a tympanic membrane is arranged in the medium flow cavity group and controls the liquid flow, the tympanic membrane is installed in the valve body through a connecting structure, the tympanic membrane is elastically connected with the connecting structure, a pressure detection structure is installed on the valve body and can move up and down after being pressed, the pressure detection structure is communicated with the medium flow cavity group, and a pressing structure is arranged on the upside of the tympanic membrane and can move up and down. When the medium pressure in the medium flow cavity group is too large, the pressure detection structure is controlled by the linkage structure to press the tympanic membrane downward through the pressing structure, the pressing structure supports and blocks the upside of the tympanic membrane, so that the medium cannot pass through the tympanic membrane, and the damage of the medium to the tympanic membrane and the subsequent structure is reduced.

Devices and systems for monitoring and measuring arterial carbon dioxide include an occlusive earpiece, a housing and a carbon dioxide sensor. The occlusive earpiece is configured to provide a hermetic seal enclosing a patient's external auditory canal, and the hermetic seal creates equilibration between airspace contained in the external auditory canal and the arterial blood vessels. The carbon dioxide sensor measures arterial carbon dioxide levels in arterial blood vessels of a patient's tympanic membrane and external auditory canal and may be located within the housing or at a proximal or distal end of the occlusive earpiece. A pressure sensor may also be provided to measure pressure changes in a patient's ear. The occlusive earpiece may define a tube running therethrough and may have a diffusible membrane that allows diffusion of carbon dioxide into the tube.

The application relates to the field of biological medicine, and particularly relates to a cold storage solution and application of a combined traditional Chinese medicine compound biological stent drug delivery system in eardrum repair. The cold storage solution comprises a basic solution and L-alanyl-L-glutamine; the basic solution comprises a STEEN solution. The cold storage solution can promote metabolism and synthesis of glutathione of fat grafts, regulate ROS mitochondrial oxidative stress, reduce cold storage damage of the fat grafts, and improve the cold storage quality of the fat grafts. Meanwhile, the application uses Shengji Yuhong collagen sponge which contains an important classical prescription for promoting repair, forms a functional biological material with supporting and pro-angiogenic effects, forms a linkage mode of "double-stage regulation before and after transplantation", closely combines the actual difficulties of cell damage of fat groups and reduction of repair success rate caused by long eardrum repair time in the clinic, explores a brand-new research mode for improving the eardrum repair scheme, and has far-reaching clinical significance.