62 results about "Amorphous calcium carbonate" patented technology

The invention relates to the technical field of amorphous calcium carbonate preparation, in particular to rosin-coated stable amorphous calcium carbonate and a preparation method and application thereof. Preparing a polyaspartic acid solution, adding an alcohol organic solvent to obtain a composite solvent, adding the regenerated micro-powder into the composite solvent, stirring and uniformly mixing to obtain a suspension, injecting CO2, and carrying out wet carbonization, vacuum filtration separation, washing and drying to obtain regenerated micro-powder micron particles containing ACC; the preparation method comprises the following steps: adding the calcium carbonate into a rosin solvent, uniformly stirring and mixing, and then carrying out vacuum filtration separation, washing and drying to obtain the rosin-packaged amorphous calcium carbonate micron particles. A uniform coating layer can be formed on the surfaces of ACC particles in a viscous solvent state, so that the influence of moisture on ACC crystallization is fully isolated, and the ACC stability is effectively maintained. Meanwhile, controllable dissolution is achieved through protonation in an alkaline environment, the gelling function of calcium carbonate can be recovered in a cement system, and the material performance is improved.

The invention provides a method for synthesizing high-valued amorphous calcium carbonate through carbon sequestration of carbide slag, and belongs to the technical field of carbon sequestration and high-valued utilization of industrial solid waste resources. The method comprises the following steps: carrying out active calcium extraction reaction on a dried and ball-milled carbide slag aqueous solution through ammonium chloride, stirring and filtering to obtain a calcium-containing solution; the method comprises the following steps: adding a certain amount of absolute ethyl alcohol and magnesium chloride into a calcium-containing solution, fully stirring, adjusting the pH value to a certain value, and introducing CO2 gas for mineralization reaction to obtain a turbid liquid containing calcium carbonate precipitate; and carrying out centrifugal separation, alcohol washing and drying on the turbid liquid to obtain powder calcium carbonate. According to the method disclosed by the invention, the calcium carbide slag active calcium liquid is extracted by adopting ammonium chloride, and absolute ethyl alcohol-magnesium chloride is added to precisely regulate and control the reaction steps of CO2 and the extracted calcium liquid, so that the CO2 is efficiently fixed, and meanwhile, mineralization is performed to obtain a mixed crystal type amorphous nano calcium carbonate product. According to the technology, double targets of synthesizing high-valued calcium carbonate through carbide slag carbon sequestration are achieved, and an innovative technical path is invented for current solid waste resource utilization.

The invention provides glycerol-stabilized amorphous calcium carbonate as well as a preparation method and application thereof. The preparation method of the glycerin-stabilized amorphous calcium carbonate comprises the following steps: dissolving a carbon source in a first solvent to obtain a first solution; dissolving a calcium source and a magnesium source in a second solvent to obtain a second solution; adding the second solution into the first solution to obtain a mixed solution, heating the mixed solution, and reacting to obtain a colloidal mixture; washing the colloidal mixture with absolute ethyl alcohol, and drying to obtain glycerol-stabilized amorphous calcium carbonate; wherein the first solvent is glycerol, and the second solvent is absolute ethyl alcohol. The preparation method disclosed by the invention is simple, does not need additional additives, and is low in raw material variety and raw material dosage, low in cost and low in production cost; the prepared calcium carbonate cluster can stably exist in a glycerol and / or absolute ethyl alcohol solution, and no agglomeration phenomenon occurs; the prepared glycerol-stabilized amorphous calcium carbonate can be used in the fields of drying, dehumidification, air water collection and the like.

The invention discloses a preparation method of calcium carbonate whiskers, which comprises the following steps: seed crystal preparation and calcium carbonate synthesis are respectively carried out in two reaction kettles, and after calcium carbonate whisker slurry is prepared, the slurry is dehydrated, dried, crushed and packaged to obtain a calcium carbonate whisker product. The method can effectively solve the problems of harsh conditions required by whisker seed crystal synthesis and synthesis of amorphous calcium carbonate by using low-concentration tail gas, and the amorphous calcium carbonate is induced to be converted into the calcium carbonate whisker by using the whisker in the later reaction, so that the content of the calcium carbonate whisker is effectively increased.

The invention discloses an MMP-9-targeted MRI (Magnetic Resonance Imaging) nanoprobe and a preparation method and application thereof, the MMP-9-targeted MRI nanoprobe is represented by Gd-ACC-MAP and comprises amorphous calcium carbonate and an aptamer covalently connected to the surface of the amorphous calcium carbonate, the calcium carbonate is doped with gadolinium, and the aptamer has a nucleotide sequence as shown in SEQ ID NO: 1. The MRI nanoprobe can be used for early diagnosis of aneurysm and evaluation of rupture risk of the aneurysm.

The present invention belongs to the technical field of nanomaterials, and particularly relates to a composite material containing platinum nanozyme, a preparation method thereof and an application. The composite material forms a hydrophobic layer with phase change melting on the surface of amorphous calcium carbonate nanoparticles through electrostatic interaction and coordination with fatty acids. On the surface of the hydrophobic layer, a photothermal effect layer with a photothermal effect is formed with a self-oxidizing polymer through self-oxidizing polymerization. After fixing platinum ions on the surface of the photothermal effect layer, in-situ reduction is carried out to obtain the composite material; the self-oxidizing polymer is dopamine. The composite material of the present invention can change the pH of the wound microenvironment to regulate the POD and CAT activities of the nanozyme, so as to meet the needs of different stages of infectious wound treatment.

The application discloses a polylactic acid / calcium carbonate papermaking coating composite pigment and a preparation method and application thereof, and belongs to the technical field of papermaking. In the application, under high-speed stirring at pH 7.6-7.8, a carbonate aqueous solution is added dropwise into a calcium salt solution, and porous amorphous calcium carbonate particles are prepared through reaction; the porous amorphous calcium carbonate particles are added into polylactic acid, the polylactic acid fills the internal pores of the porous amorphous calcium carbonate particles and coats the particles, and the polylactic acid / calcium carbonate papermaking coating composite pigment is obtained. The polylactic acid / calcium carbonate papermaking coating composite pigment prepared in the application has uniform particle size distribution, improved light scattering capacity, low coating viscosity, good coating performance, high surface strength, smoothness, whiteness and opacity of coated paper; the polylactic acid is biodegradable and environment-friendly, and the mechanical strength, wear resistance and thermal stability of the coating are improved.

The invention discloses a preparation method of a calcium carbonate-polyvinyl alcohol composite aerogel material, and belongs to the technical field of thermal insulation materials. The invention aims to solve the problems that the crystallization behavior of calcium carbonate is difficult to effectively regulate and control and the porous structure and the heat insulation function of aerogel are easily damaged in the prior art. The method comprises the following steps: reacting a mixed solution of calcium chloride and magnesium chloride with carbon dioxide to prepare micro-nano amorphous calcium carbonate and a small amount of nano calcite; co-doping the chitosan and aspartic acid into polyvinyl alcohol hydrogel, uniformly mixing, and carrying out directional freezing and freeze-drying treatment; finally, high-concentration carbon dioxide atmosphere treatment is adopted in a humid and hot environment, amorphous calcium carbonate is induced to be dissolved on the polyvinyl alcohol framework and recrystallized into calcite and vaterite shell layers, and therefore the composite aerogel material is obtained. While good heat insulation performance and flexibility are maintained, the mechanical strength and damp and heat resistance stability of the material are remarkably improved, efficient curing and utilization of carbon dioxide are achieved, and the material is suitable for the field of green energy-saving buildings.

Methods for immobilizing carbon dioxide and producing stabilized amorphous alkaline earth metal carbonates are provided.

Various aspects relate to production of synthetic aragonite material. In some aspects direct precipitation of aragonite, via controlling certain environmental conditions, is disclosed. In some aspects aragonite crystals may grow on seeds of other particles, such as aragonite crystals, to produce long aragonite structures. In some aspect, metastable calcium carbonate such as vaterite or amorphous calcium carbonate is transformed into aragonite. In various aspects different compositions of calcium carbonate polymorphs, including aragonite, with different aspect ratios are used to produce cementitious or non-cementitious compositions with superior properties.

The invention belongs to the technical field of nano materials, and particularly relates to a platinum-containing nano enzyme composite material and a preparation method and application thereof. The composite material is characterized in that a hydrophobic layer with phase change melting is formed on the surface of amorphous calcium carbonate nanoparticles and fatty acid through electrostatic interaction and coordination, and a photothermal effect layer with a photothermal effect is formed on the surface of the hydrophobic layer and an autoxidation polymer through autoxidation polymerization. Fixing platinum ions on the surface of the photothermal effect layer, and then performing in-situ reduction to obtain the composite material, the self-oxidation polymer is dopamine. The composite material provided by the invention can change the pH of the wound microenvironment to adjust the POD and CAT activity of the nano enzyme so as to meet the requirements of different stages of infectious wound treatment.

A method of making a carbon dioxide-based cementitious product includes: providing a calcium chloride solution and an ammonia source; and mixing the calcium chloride solution and the ammonia source with a bacteria solution (e.g., of Sporosarcina pasteurii) to obtain a cementitious product, wherein the cementitious product includes amorphous calcium carbonate. A cementitious product including an amorphous calcium carbonate (ACC) and a bacteria distributed thereon may be provided in the form of a slurry or a powder. A use of the cementitious product to treat a soil may include: forming the cementitious product from a mixture of calcium chloride and a bacteria solution; and adding the cementitious product to the soil to form a treated soil, wherein the cementitious product includes ACC. The treated soil includes calcite and the aggregate particles bonded together. The cementitious product may also be used to make building components.

The application discloses a super-strong bonding water-based adhesive and a preparation method thereof, and relates to the technical field of adhesives. In a dispersion system of aluminum gel, cellulose nanocrystals and surface-carboxylated amorphous calcium carbonate, chemical bonding and uniform dispersion of nano-filler and a polymer matrix are realized through in-situ polymerization of polyurethane monomers, so that excellent bonding strength and water resistance are realized. Aluminum ions and carboxymethyl cellulose sodium form an ionic gel structure, the mechanical embedding of the adhesive and the base material is enhanced, amorphous calcium carbonate is wrapped with acrylic acid polymerization, so that the nanoparticles are stabilized, calcium carbonate is diffused into the polyurethane matrix to realize the organic-inorganic hybrid reinforcing structure of the adhesive, and the polyurethane monomers are in-situ polymerized in the presence of nano-filler, so that the crystal form of calcium carbonate and the mechanical properties of the adhesive are stabilized, and the overall structural integrity of the matrix is enhanced.

The present invention provides a method for fixing carbon dioxide and a method for preparing stabilized amorphous alkaline earth metal carbonates.

The invention belongs to the technical field of industrial byproduct waste recycling and reusing, and particularly discloses a recycling and reusing method for byproduct magnesium waste residues in magnesium smelting. According to the recycling and reusing method, the magnesium slag micro powder can be directly converted into the magnesium slag carbon sequestration cementing material under the action of valine. The valine not only can promote dissolution of calcium ions in the magnesium slag micro powder, but also can promote generation of more stable carbonization products, namely amorphous calcium carbonate; and the magnesium slag can also be used as a nucleation site to generate a stable organic-inorganic composite carbonized product in situ, so that the strength of the magnesium slag carbon sequestration cementing material is greatly improved. Moreover, the recycling method also avoids the problem that the strength development of products is easily hindered due to the adoption of high-concentration and high-pressure carbonization maintenance conditions during traditional magnesium slag recycling, carbonization maintenance can be carried out by using low-concentration carbon dioxide under a low-pressure condition, and the recycling method is simple in process and low in cost. The method has practical significance on in-situ digestion of magnesium smelting byproduct waste gas slag.

The present application provides methods of increasing the sensitivity of antibiotic-resistant bacteria to an antibiotic to which the bacteria are resistant using stabilized amorphous calcium carbonate and therefore allows more efficient treatment of diseases caused by these bacteria. In addition, the application provides methods for inhibiting or preventing the formation of a biofilm. Further, the application is directed to methods of treating an oral bacterial infection using stabilized ACC, while the stabilized ACC is an active agent used.

The invention relates to a bionic nano-platform for synergistic treatment, the bionic nano-platform comprises a core and a shell, the core comprises hollow calcium carbonate and manganese carbonate, the shell comprises a cell membrane and a fluorescent dye, and the shell covers the surface of the core. The preparation method comprises the following steps: synthesizing amorphous calcium carbonate; preparing hollow calcium carbonate; preparing hollow calcium carbonate-manganese carbonate nanoparticles; coating the cell membrane; and loading the fluorescent dye. The bionic nano platform for collaborative treatment can integrate multiple functions of gas release, photo-thermal heat production, immune regulation and control, in-vivo imaging and the like, and is used for collaborative treatment of liver cancer.

Various aspects relate to production of synthetic aragonite material. In some aspects direct precipitation of aragonite, via controlling certain environmental conditions, is disclosed. In some aspects aragonite crystals may grow on seeds of other particles, such as aragonite itself, to produce long aragonite structures. In some aspect, metastable calcium carbonate such as vaterite or amorphous calcium carbonate is transformed into aragonite. In various aspects different compositions of calcium carbonate polymorphs, including aragonite, with different aspect ratios are used to produce cementitious or non-cementitious compositions with superior properties.

The purpose of the present invention is to provide a thermosetting epoxy resin composition which is capable of preventing deterioration of reliability due to long-term storage while improving durability against heat generation and vibration after curing.　A thermosetting epoxy resin composition according to the present disclosure is characterized by: containing an epoxy compound (A), an acid anhydride-based curing agent (B), a curing accelerator (C), a silane coupling agent (D), a defoaming agent (E), and an inorganic filler (F), wherein the inorganic filler (F) is a resin composition that contains spherical silica and amorphous calcium carbonate, and the content of the spherical silica is 50-90 mass% and the content of the amorphous calcium carbonate is 5-50 mass% with respect to the total amount of the resin composition; and being in liquid state at 25°C.

The application discloses a kind of solid waste-based calcium carbonate low-carbon cementing material and its preparation method and application, calcium-based solid waste and ammonium acetate solution occur leaching reaction, after reaction, calcium acetate leaching liquid is obtained by centrifugal separation;The calcium acetate leaching liquid is placed in CO2 mineralization reactor, and a dispersion control agent is added, and CO2 is introduced to carry out mineralization reaction, and the solid waste-based calcium carbonate low-carbon cementing material is obtained by centrifugal separation after reaction.The application prepares solid waste-based calcium carbonate low-carbon cementing material by the technical route of CO2 mineralization indirect mineralization with calcium-based solid waste material as raw material, makes full use of solid waste, and reduces environmental pollution caused by large-area stockpiling.Amorphous calcium carbonate is used as precursor, and the crystalline phase of amorphous calcium carbonate is converted during cement hydration, which improves the performance of cementing material.

Stabilized amorphous calcium carbonate (ACC) for treatment of several neurological, muscular and infertility diseases and conditions is provided. In particular, the stabilized ACC may be used in the treatment of axonal defects and muscular dystrophy. In addition, provided are improved methods used in assistant reproductive technology. Examples of such methods are in vitro fertilization and improvement of sperm quality. The improved IVF method, for example, comprises addition of the stabilized ACC to the cell culture medium in which the stages of fertilization and embryo development occurs.

The application belongs to the technical field of florfenicol medicine preparation, and specifically provides florfenicol nanoemulsion and a preparation method thereof. The florfenicol nanoemulsion is composed of an oil phase, an aqueous phase and a composite emulsification stabilizing solution. The composite emulsification stabilizing solution comprises a non-ionic surfactant, a co-surfactant and a polysaccharide stabilizing solution. The polysaccharide stabilizing solution is obtained after in-situ mineralization of a calcium source to generate amorphous calcium carbonate with a degradation product of kappa-carrageenan and sodium phytate as a synergistic mineralization regulator. The florfenicol nanoemulsion prepared by the application has the advantages of good stability, uniform particle size distribution and high bioavailability.

The invention discloses a bortezomib and illicit loaded targeted copper / calcium bimetal-based nanocage and a preparation method and application thereof, and the preparation method comprises the following steps: carrying out in-situ etching on amorphous calcium carbonate nanospheres by using a copper chloride aqueous solution to form the copper / calcium bimetal-based nanocage; the preparation method comprises the following steps: loading bortezomib and illicit in a nanocage under the coordination action to form a bortezomib and illicit loaded copper / calcium bimetal-based nanocage; and then carrying out surface modification by using hydrazide hyaluronic acid to form the bortezomib and illicit loaded targeted copper / calcium double-metal-based nanocage capable of specifically acting with cancer cells. The copper / calcium bimetal-based nanocage has the structural characteristics of large specific surface area, moderate particle size and pore size, capability of coordinating and combining a plurality of groups and the like, is high in drug loading capacity, and has pH / glutathione dual responsiveness and Fenton-like catalytic reaction characteristics. According to the invention, the bortezomib and the illicit are loaded in the nanocage through coordination, and the drug loading rates respectively reach 13.9% and 31.7%; the final nanocage has a tumor targeting function and can efficiently trigger cancer cell endoplasmic reticulum stress and nematode damage, and the synergistic amplification effect of the two can significantly enhance the immunotherapy effect.

The invention discloses a preparation method of an Mg < 2 + >-mediated Eu-containing amorphous calcium carbonate luminescent nano material, and belongs to the technical field of solid-state photoluminescent materials. According to the method, Ca salt, Eu salt and Mg salt serve as raw materials to prepare mineralization mother liquor, then (NH4) 2CO3 solid is decomposed into CO2 and NH3 through an ammonium carbonate diffusion method (ADM), the CO2 and the NH3 penetrate through a gas-liquid interface to be diffused into the mother liquor to be subjected to mineralization reaction, nucleation and growth of calcite, aragonite and other crystal forms are delayed due to existence of Mg < 2 + > at the moment, and the mineralization effect is achieved. The service life of the amorphous calcium carbonate is prolonged, and Eu < 3 + > is sealed in the structure of the amorphous calcium carbonate, so that the Eu-containing amorphous calcium carbonate luminescent nano material with high rare earth doping concentration and highly uniform distribution is obtained.

Methods of producing a building material are provided. Methods of interest include preparing a carbonate slurry comprising amorphous calcium carbonate and structural water. Aspects of the invention also include building materials (e.g., aggregates) as well as compositions (e.g., concrete dry composites, settable compositions and built structures) that include building materials produced via the subject methods.

The present invention provides a method for the treatment and / or prevention of myocardial ischemia and myocardial infarction, comprising administering a composition containing stabilized amorphous calcium carbonate.

The present invention provides methods for enhancing and improving athletic performances of both professional and non-professional athletes by administering compositions comprising stabilized amorphous calcium carbonate. The enhanced athletic performances result among others from enhanced muscle performances, enhanced recovery and endurance.

The invention discloses a viscosity modifier based on machine-made sand waste mud and a preparation method thereof. The viscosity modifier is a viscosity modified microsphere which is prepared from waste mud microspheres, a calcium hydroxide solution, a sodium hydroxide solution, a sodium carbonate solution, a sodium phosphate solution, amorphous calcium carbonate and an oil phase, takes calcium carbonate as a framework and contains a large number of pores, and the pores are filled with polyacrylate. The waste slurry microspheres are particles with the particle size of 0.15 mm or less, and the particles are obtained by spraying waste slurry after the waste slurry is atomized by sludge atomization equipment. According to the method, the waste mud obtained after machine-made sand washing is modified, the porous structure microspheres which have the viscosity reduction effect and mainly take calcium carbonate are obtained, reduction of the viscosity of concrete is facilitated, meanwhile, the strength of the concrete is guaranteed, and therefore resource utilization of the waste mud obtained after machine-made sand washing is achieved.

The present invention belongs to the technical field of environmental governance, and specifically relates to a biogenic amorphous calcium carbonate for dye wastewater treatment, and a preparation method and application thereof. Bacillus licheniformis LRL007 is inoculated into a liquid culture medium containing a soluble inorganic calcium salt for cultivation to obtain the biogenic amorphous calcium carbonate; the Bacillus licheniformis LRL007 has been deposited in the General Microbiology Center of the China Committee for the Collection of Microorganisms on January 10, 2022, with a deposit number of CGMCC No. 24275. The preparation method of the present invention is economical and environmentally friendly, simple to operate, and no toxic or harmful substances are added during the synthesis process, and no secondary pollution will be caused; the obtained amorphous calcium carbonate has good stability, a well-developed porous structure and good organic dye adsorption and anti-interference ability. At the same time, its pH applicability range is wide, and it can be recycled at least 8 times or more, and has good application prospects in the treatment of organic dye wastewater.

The invention discloses a calcium carbonate / calcium phosphate composite hollow nanosphere as well as a preparation method and application thereof, the preparation method comprises the following steps: mixing an alcohol suspension of amorphous calcium carbonate nanospheres with an aqueous solution of phosphoric acid, pyrophosphoric acid, metaphosphoric acid, orthophosphate, pyrophosphate, metaphosphate, tripolyphosphate or phosphonic acid organic matters, reacting and centrifuging to obtain an amorphous calcium carbonate nanosphere solution; the calcium carbonate / calcium phosphate composite hollow nanospheres are obtained. The preparation method disclosed by the invention has the advantages of mild reaction conditions, simple preparation steps, high reaction speed and good large-scale production prospect, and the obtained calcium carbonate / calcium phosphate composite hollow nanospheres have the characteristics of uniform particle size, controllable size, good dispersity and high stability. The method has application prospects in the fields of rubber, plastics, papermaking, printing ink, coatings, daily chemical products, agricultural and biomedical materials and the like.