32 results about "Amorphous calcium carbonate" patented technology

The invention provides a method for synthesizing high-valued amorphous calcium carbonate through carbon sequestration of carbide slag, and belongs to the technical field of carbon sequestration and high-valued utilization of industrial solid waste resources. The method comprises the following steps: carrying out active calcium extraction reaction on a dried and ball-milled carbide slag aqueous solution through ammonium chloride, stirring and filtering to obtain a calcium-containing solution; the method comprises the following steps: adding a certain amount of absolute ethyl alcohol and magnesium chloride into a calcium-containing solution, fully stirring, adjusting the pH value to a certain value, and introducing CO2 gas for mineralization reaction to obtain a turbid liquid containing calcium carbonate precipitate; and carrying out centrifugal separation, alcohol washing and drying on the turbid liquid to obtain powder calcium carbonate. According to the method disclosed by the invention, the calcium carbide slag active calcium liquid is extracted by adopting ammonium chloride, and absolute ethyl alcohol-magnesium chloride is added to precisely regulate and control the reaction steps of CO2 and the extracted calcium liquid, so that the CO2 is efficiently fixed, and meanwhile, mineralization is performed to obtain a mixed crystal type amorphous nano calcium carbonate product. According to the technology, double targets of synthesizing high-valued calcium carbonate through carbide slag carbon sequestration are achieved, and an innovative technical path is invented for current solid waste resource utilization.

The invention discloses an MMP-9-targeted MRI (Magnetic Resonance Imaging) nanoprobe and a preparation method and application thereof, the MMP-9-targeted MRI nanoprobe is represented by Gd-ACC-MAP and comprises amorphous calcium carbonate and an aptamer covalently connected to the surface of the amorphous calcium carbonate, the calcium carbonate is doped with gadolinium, and the aptamer has a nucleotide sequence as shown in SEQ ID NO: 1. The MRI nanoprobe can be used for early diagnosis of aneurysm and evaluation of rupture risk of the aneurysm.

The application discloses a polylactic acid / calcium carbonate papermaking coating composite pigment and a preparation method and application thereof, and belongs to the technical field of papermaking. In the application, under high-speed stirring at pH 7.6-7.8, a carbonate aqueous solution is added dropwise into a calcium salt solution, and porous amorphous calcium carbonate particles are prepared through reaction; the porous amorphous calcium carbonate particles are added into polylactic acid, the polylactic acid fills the internal pores of the porous amorphous calcium carbonate particles and coats the particles, and the polylactic acid / calcium carbonate papermaking coating composite pigment is obtained. The polylactic acid / calcium carbonate papermaking coating composite pigment prepared in the application has uniform particle size distribution, improved light scattering capacity, low coating viscosity, good coating performance, high surface strength, smoothness, whiteness and opacity of coated paper; the polylactic acid is biodegradable and environment-friendly, and the mechanical strength, wear resistance and thermal stability of the coating are improved.

The invention discloses a preparation method of a calcium carbonate-polyvinyl alcohol composite aerogel material, and belongs to the technical field of thermal insulation materials. The invention aims to solve the problems that the crystallization behavior of calcium carbonate is difficult to effectively regulate and control and the porous structure and the heat insulation function of aerogel are easily damaged in the prior art. The method comprises the following steps: reacting a mixed solution of calcium chloride and magnesium chloride with carbon dioxide to prepare micro-nano amorphous calcium carbonate and a small amount of nano calcite; co-doping the chitosan and aspartic acid into polyvinyl alcohol hydrogel, uniformly mixing, and carrying out directional freezing and freeze-drying treatment; finally, high-concentration carbon dioxide atmosphere treatment is adopted in a humid and hot environment, amorphous calcium carbonate is induced to be dissolved on the polyvinyl alcohol framework and recrystallized into calcite and vaterite shell layers, and therefore the composite aerogel material is obtained. While good heat insulation performance and flexibility are maintained, the mechanical strength and damp and heat resistance stability of the material are remarkably improved, efficient curing and utilization of carbon dioxide are achieved, and the material is suitable for the field of green energy-saving buildings.

Various aspects relate to production of synthetic aragonite material. In some aspects direct precipitation of aragonite, via controlling certain environmental conditions, is disclosed. In some aspects aragonite crystals may grow on seeds of other particles, such as aragonite crystals, to produce long aragonite structures. In some aspect, metastable calcium carbonate such as vaterite or amorphous calcium carbonate is transformed into aragonite. In various aspects different compositions of calcium carbonate polymorphs, including aragonite, with different aspect ratios are used to produce cementitious or non-cementitious compositions with superior properties.

The application discloses a super-strong bonding water-based adhesive and a preparation method thereof, and relates to the technical field of adhesives. In a dispersion system of aluminum gel, cellulose nanocrystals and surface-carboxylated amorphous calcium carbonate, chemical bonding and uniform dispersion of nano-filler and a polymer matrix are realized through in-situ polymerization of polyurethane monomers, so that excellent bonding strength and water resistance are realized. Aluminum ions and carboxymethyl cellulose sodium form an ionic gel structure, the mechanical embedding of the adhesive and the base material is enhanced, amorphous calcium carbonate is wrapped with acrylic acid polymerization, so that the nanoparticles are stabilized, calcium carbonate is diffused into the polyurethane matrix to realize the organic-inorganic hybrid reinforcing structure of the adhesive, and the polyurethane monomers are in-situ polymerized in the presence of nano-filler, so that the crystal form of calcium carbonate and the mechanical properties of the adhesive are stabilized, and the overall structural integrity of the matrix is enhanced.

The invention relates to a bionic nano-platform for synergistic treatment, the bionic nano-platform comprises a core and a shell, the core comprises hollow calcium carbonate and manganese carbonate, the shell comprises a cell membrane and a fluorescent dye, and the shell covers the surface of the core. The preparation method comprises the following steps: synthesizing amorphous calcium carbonate; preparing hollow calcium carbonate; preparing hollow calcium carbonate-manganese carbonate nanoparticles; coating the cell membrane; and loading the fluorescent dye. The bionic nano platform for collaborative treatment can integrate multiple functions of gas release, photo-thermal heat production, immune regulation and control, in-vivo imaging and the like, and is used for collaborative treatment of liver cancer.

Various aspects relate to production of synthetic aragonite material. In some aspects direct precipitation of aragonite, via controlling certain environmental conditions, is disclosed. In some aspects aragonite crystals may grow on seeds of other particles, such as aragonite itself, to produce long aragonite structures. In some aspect, metastable calcium carbonate such as vaterite or amorphous calcium carbonate is transformed into aragonite. In various aspects different compositions of calcium carbonate polymorphs, including aragonite, with different aspect ratios are used to produce cementitious or non-cementitious compositions with superior properties.

The purpose of the present invention is to provide a thermosetting epoxy resin composition which is capable of preventing deterioration of reliability due to long-term storage while improving durability against heat generation and vibration after curing.　A thermosetting epoxy resin composition according to the present disclosure is characterized by: containing an epoxy compound (A), an acid anhydride-based curing agent (B), a curing accelerator (C), a silane coupling agent (D), a defoaming agent (E), and an inorganic filler (F), wherein the inorganic filler (F) is a resin composition that contains spherical silica and amorphous calcium carbonate, and the content of the spherical silica is 50-90 mass% and the content of the amorphous calcium carbonate is 5-50 mass% with respect to the total amount of the resin composition; and being in liquid state at 25°C.

The application discloses a kind of solid waste-based calcium carbonate low-carbon cementing material and its preparation method and application, calcium-based solid waste and ammonium acetate solution occur leaching reaction, after reaction, calcium acetate leaching liquid is obtained by centrifugal separation;The calcium acetate leaching liquid is placed in CO2 mineralization reactor, and a dispersion control agent is added, and CO2 is introduced to carry out mineralization reaction, and the solid waste-based calcium carbonate low-carbon cementing material is obtained by centrifugal separation after reaction.The application prepares solid waste-based calcium carbonate low-carbon cementing material by the technical route of CO2 mineralization indirect mineralization with calcium-based solid waste material as raw material, makes full use of solid waste, and reduces environmental pollution caused by large-area stockpiling.Amorphous calcium carbonate is used as precursor, and the crystalline phase of amorphous calcium carbonate is converted during cement hydration, which improves the performance of cementing material.

Stabilized amorphous calcium carbonate (ACC) for treatment of several neurological, muscular and infertility diseases and conditions is provided. In particular, the stabilized ACC may be used in the treatment of axonal defects and muscular dystrophy. In addition, provided are improved methods used in assistant reproductive technology. Examples of such methods are in vitro fertilization and improvement of sperm quality. The improved IVF method, for example, comprises addition of the stabilized ACC to the cell culture medium in which the stages of fertilization and embryo development occurs.

The application belongs to the technical field of florfenicol medicine preparation, and specifically provides florfenicol nanoemulsion and a preparation method thereof. The florfenicol nanoemulsion is composed of an oil phase, an aqueous phase and a composite emulsification stabilizing solution. The composite emulsification stabilizing solution comprises a non-ionic surfactant, a co-surfactant and a polysaccharide stabilizing solution. The polysaccharide stabilizing solution is obtained after in-situ mineralization of a calcium source to generate amorphous calcium carbonate with a degradation product of kappa-carrageenan and sodium phytate as a synergistic mineralization regulator. The florfenicol nanoemulsion prepared by the application has the advantages of good stability, uniform particle size distribution and high bioavailability.

The invention discloses a bortezomib and illicit loaded targeted copper / calcium bimetal-based nanocage and a preparation method and application thereof, and the preparation method comprises the following steps: carrying out in-situ etching on amorphous calcium carbonate nanospheres by using a copper chloride aqueous solution to form the copper / calcium bimetal-based nanocage; the preparation method comprises the following steps: loading bortezomib and illicit in a nanocage under the coordination action to form a bortezomib and illicit loaded copper / calcium bimetal-based nanocage; and then carrying out surface modification by using hydrazide hyaluronic acid to form the bortezomib and illicit loaded targeted copper / calcium double-metal-based nanocage capable of specifically acting with cancer cells. The copper / calcium bimetal-based nanocage has the structural characteristics of large specific surface area, moderate particle size and pore size, capability of coordinating and combining a plurality of groups and the like, is high in drug loading capacity, and has pH / glutathione dual responsiveness and Fenton-like catalytic reaction characteristics. According to the invention, the bortezomib and the illicit are loaded in the nanocage through coordination, and the drug loading rates respectively reach 13.9% and 31.7%; the final nanocage has a tumor targeting function and can efficiently trigger cancer cell endoplasmic reticulum stress and nematode damage, and the synergistic amplification effect of the two can significantly enhance the immunotherapy effect.

Methods of producing a building material are provided. Methods of interest include preparing a carbonate slurry comprising amorphous calcium carbonate and structural water. Aspects of the invention also include building materials (e.g., aggregates) as well as compositions (e.g., concrete dry composites, settable compositions and built structures) that include building materials produced via the subject methods.

The present invention provides a method for the treatment and / or prevention of myocardial ischemia and myocardial infarction, comprising administering a composition containing stabilized amorphous calcium carbonate.

The invention provides a solid lubricating coating based on graphene-amorphous calcium carbonate. Raw materials of the solid lubricating coating comprise a solid lubricating phase and an auxiliary agent, the solid lubricating phase takes a graphene nanosheet as a matrix, and amorphous calcium carbonate is loaded on the surface of the solid lubricating phase; and the auxiliary agent is ethyl cellulose. The solid lubricating phase can form a friction film on the friction surface, so that the friction coefficient is reduced, the auxiliary agent can be combined with the solid lubricating phase to form a fixed coating film, the bearing capacity of the film is increased, and the solid lubricating coating is prevented from being easily crushed or punctured; meanwhile, the friction surface is protected by the transfer film, the friction oxidation reaction is avoided, and the surface abrasion is reduced.

The present invention provides stable amorphous calcium carbonate (ACC) compositions, and food articles comprising said compositions.

The present invention provides a method for treating and / or preventing myocardial ischemia and myocardial infarction, the method comprising administering a composition comprising stabilized amorphous calcium carbonate.

The invention provides a microbial mineralization preparation method of a high-loading serum albumin-mineral composite carrier, and belongs to the crossing field of biological medicine and microbial technology. According to the method, microorganisms with a mineralization function, serum albumin and mineralization liquid containing a calcium source and urea are used as a reaction system, under the mild condition, the microorganisms hydrolyze urea to generate carbonate radicals and release the carbonate radicals to the outside of cells, calcium ions are actively transported to the outside of the cells through a calcium ion pump, the pH and ion saturation of the local microenvironment are adjusted, and the calcium ions in the microenvironment are converted into calcium ions. According to the present invention, the formation of the calcium carbonate precursor is slowly and continuously driven, and the serum albumin is completely embedded into the mineral precursor to provide the nucleation site and the organic template so as to regulate and stabilize the formation of the serum albumin-amorphous calcium carbonate mineral phase composite carrier, such that the high loading and the uniform distribution of the serum albumin in the carrier can be achieved; the natural structure of the serum albumin can be effectively maintained.

The application discloses a kind of Mg 2+ Preparation method of Eu-containing amorphous calcium carbonate luminescent nanomaterial under mediation, belong to solid-state photoluminescence material technical field.The present application first prepares mineralization mother liquor with Ca salt, Eu salt and Mg salt as raw material, then through ammonium carbonate diffusion method (ADM), make (NH4)2CO3 solid decompose into CO2 and NH3, and make it diffuse through gas-liquid interface into mother liquor and carry out mineralization reaction, and at this time, the existence of Mg 2+ Delay the nucleation and growth of calcite and aragonite and other crystal forms, prolong the life of amorphous calcium carbonate and seal Eu 3+ In the structure of amorphous calcium carbonate, and then a rare earth doped Eu-containing amorphous calcium carbonate luminescent nanomaterial with high concentration and highly uniform distribution is obtained.

The application discloses a long-acting active self-cleaning automobile tarpaulin material and a preparation method thereof. The long-acting active self-cleaning automobile tarpaulin material is prepared by the following steps: hydrophilic activation and loading of hydrophilic surfactant on amorphous calcium carbonate microparticles, in-situ growth of silicon dioxide nanoparticles on the surface of the amorphous calcium carbonate microparticles to form super-hydrophilic microcapsules, uniform dispersion of the super-hydrophilic microcapsules in PVC paste resin, addition of a plasticizer and a stabilizer, coating on the surface of a polyester base cloth through a knife coating process, and curing at room temperature. The long-acting active self-cleaning automobile tarpaulin material is obtained. In the application, the amorphous calcium carbonate microparticles with high specific surface area are used to load the hydrophilic surfactant, so that the coating is super-hydrophilic, and the silicon dioxide nanoparticles are used for encapsulation, so that the loss of the surfactant is significantly delayed, and the long-acting active self-cleaning performance is realized. Meanwhile, the addition of the calcium carbonate particles can significantly strengthen the mechanical properties of the automobile tarpaulin material and prolong the service life of the automobile tarpaulin material.

The present invention provides methods for fixating carbon dioxide and preparation of stabilized amorphous alkaline earth metal carbonate.

The application provides application of silicon-based amorphous calcium carbonate in synchronous removal of cadmium in water bodies and soil, and removal rate of Si-ACC on cadmium in water bodies is determined according to kinetic adsorption and isothermal adsorption experiments. The Si-ACC provided by the application has a new use in synchronous control of cadmium pollution in water bodies and soil, realizes "one dose for two purposes", can treat water and soil, the adsorption amount of the Si-ACC on water body Cd(II) is greater than or equal to 111 mg / g within 5 min, and the removal rate is greater than or equal to 99%; under the condition of 20 g / kg dose, the water-soluble Cd of soil is approximately equal to 0 after 7 days, the exchangeable state decreases by greater than or equal to 34%, and the carbonate combined state increases by greater than or equal to 110%; compared with the MICP process which needs 12 rounds of grouting and a total of 36-60 days, the Si-ACC process is shortened by more than 80%.

Provided are cell culture media containing stabilized amorphous calcium carbonate (ACC) as a supplement, and cell culture medium supplements containing stabilized ACC. The stabilized ACC is particularly useful for enhancing the growth of cell and tissue cultures, gametes, and embryos in vitro. [Solution] A cell culture medium, wherein the cell culture medium is supplemented with amorphous calcium carbonate (ACC) stabilized by at least one stabilizing agent, and wherein the cell culture medium is suitable for growing biological cultures.

The invention discloses europium-doped double-shell calcium carbonate nanospheres as well as a preparation method and application thereof. The preparation method comprises the following steps: uniformly mixing an alcohol suspension of amorphous calcium carbonate nanospheres with an aqueous solution of a europium compound, reacting for 2 minutes to 2 hours, and centrifuging; the concentration of the amorphous calcium carbonate nanosphere alcohol suspension is 0.1 mg / ml-35 mg / ml, the concentration of the aqueous solution of the europium compound is 0.1 mg / ml-35 mg / ml, and the volume ratio of the amorphous calcium carbonate nanosphere alcohol suspension to the aqueous solution of the europium compound is (40: 1)-(1: 40). The preparation method disclosed by the invention has the advantages of mild reaction conditions, simple preparation steps, high reaction speed and good large-scale production prospect, and the obtained double-shell calcium carbonate nanospheres have the characteristics of uniform particle size, controllable size, good dispersity and high stability; therefore, the method has wide application prospects in the fields of rubber, plastics, papermaking, printing ink, coatings, daily chemical products, agricultural and biomedical materials and the like.

This invention discloses a method for using sludge phosphorus recovery products for soil phosphorus improvement and enhancement of available phosphorus, belonging to the field of solid waste resource utilization and soil improvement technology. This invention uses silicon-based amorphous calcium carbonate as a carrier to load sludge phosphorus to prepare PRP products. The application rate is 270–3000 mg / kg, maintaining a soil moisture content of 80%. Phosphorus release is achieved within one day of application. After PRP application, the soil inorganic phosphorus content is significantly increased (IP / TP from 16.6% to 60.3%), promoting the conversion of organic phosphorus to inorganic phosphorus (conversion rate reaches 42.39 mg / kg), and directionally regulating the calcium phosphate salt form to improve the Ca8-P / Ca... 10 The conversion of -P to Ca2-P (the increase in Ca2-P exceeded the theoretical value by 33.24 mg / kg) and the improvement of available phosphorus in the soil from level 3 to level 1, with a peak value of 1 day and long-term stability, have achieved the triple functions of phosphorus supply, phosphorus activation and phosphorus speciation regulation.

The application provides a modified amorphous calcium carbonate, a preparation method of the modified amorphous calcium carbonate and a cellulose composite paper, and the preparation method of the modified amorphous calcium carbonate comprises the following steps: (1) mixing magnesium chloride and calcium chloride in water, adding sodium carbonate, and performing reaction under stirring to generate amorphous calcium carbonate; (2) adding cationic chitosan to the reaction system obtained in the step (1) and performing reaction under stirring; and (3) washing and drying the product obtained in the step (2) to obtain the modified amorphous calcium carbonate. The modified amorphous calcium carbonate prepared by the application exhibits high affinity to protein and high stability in a dry environment, and the cellulose composite paper prepared by compounding cellulose and the modified amorphous calcium carbonate exhibits high protein affinity capacity, so that the application of the cellulose composite paper in the detection field is widened.

The invention discloses a preparation method of a concrete crystal nucleus early strength agent. The preparation method of the concrete crystal nucleus early strength agent comprises the following steps: mixing and stirring ELP protein, calcium salt, NH4Cl, 1, 3-diamino-2-hydroxypropane-N, N, N ', N'-tetraacetic acid and water, and adding the mixture, a surfactant and an auxiliary agent into an oil phase solution to form an emulsion B; preparing a sodium silicate solution, and adding the sodium silicate solution, a surfactant and an auxiliary agent into the oil phase solution to form an emulsion C; dropwise adding C into B, and adjusting and controlling the temperature of the whole reaction system through the temperature change of a water bath; finally, carbon dioxide and a chemical cross-linking agent are sequentially introduced for reaction, and the concrete crystal nucleus early strength agent is obtained. According to the invention, the nano hybrid particles of nano calcium silicate hydrate and amorphous calcium carbonate are prepared and the crystal growth of the particles is effectively controlled by utilizing the characteristic that ELP protein generates gel phase change at a critical solution temperature, so that the uniformity of crystal nucleus particles and the early strength performance of the early strength agent are improved, and the early strength of concrete is effectively improved; the long-term mechanical property of the concrete is favorably improved.

The invention discloses a method for stably preparing an amorphous precursor based on covalent cross-linking effect, and belongs to the technical field of amorphous calcium carbonate and amorphous calcium phosphate preparation, and the method mainly comprises the following steps: preparing a calcium ion solution taking absolute ethyl alcohol as a solvent, and then introducing a silane coupling agent to realize covalent cross-linking with calcium ions to obtain a precursor solution; the preparation method comprises the following steps: preparing a phosphate radical solution and a carbonate radical solution respectively by taking ethanol and glycerol as solvents, adding the precursor solution under continuous stirring, fully reacting, washing and centrifuging to obtain a gel-like amorphous product, and fully drying to obtain a powdery amorphous product. The preparation method of the amorphous precursor provided by the invention can simultaneously realize stable preparation of amorphous calcium phosphate and amorphous calcium carbonate based on a covalent cross-linking principle, the used cross-linking agent has excellent biocompatibility, and the preparation method is an ideal preparation method of an amorphous precursor material.

This invention belongs to the field of biomedical technology and discloses a bone-targeting platform based on black phosphorus and amorphous calcium carbonate, its preparation method, and its applications. In this invention, amorphous calcium carbonate (ACC) is coated onto the surface of bone apatite (BP) to form the core (BA) of a nano-therapeutic platform. Subsequently, a polydopamine (PDA) layer is coated on the surface, and a bone-targeting ligand (polyacrylic acid-aldehyde PA) is further coupled to the PDA layer. After BA@PDA-PA precisely accumulates in bone tissue, it reacts to the acidic microenvironment and undergoes "autolysis-like" degradation, rapidly releasing BP and calcium carbonate. 2+ Released BP can scavenge ROS in the bone microenvironment and improve the bone immune microenvironment. Furthermore, BP and Ca... 2+ As a "raw material" for bone matrix mineralization, it synergistically promotes osteoogenesis and inhibits osteoclast activity, ultimately achieving a precise and multi-effect treatment for osteoporosis (OP).