Coating of dental prosthetic surfaces comprising distinct layer of synthetic hydroxyapatite

A technology of hydroxyapatite and biomimetic apatite, applied in the direction of coating, dentistry, prosthesis, etc., to achieve the effect of reducing the risk of inflammation

Inactive Publication Date: 2018-01-02
古萨有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

A major disadvantage of amorphous calcium phosphate is its solub

Method used

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  • Coating of dental prosthetic surfaces comprising distinct layer of synthetic hydroxyapatite
  • Coating of dental prosthetic surfaces comprising distinct layer of synthetic hydroxyapatite
  • Coating of dental prosthetic surfaces comprising distinct layer of synthetic hydroxyapatite

Examples

Experimental program
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Embodiment Construction

[0106] The production of the gel is explained next in the experiments carried out. Crosslinking using glutaraldehyde (GDA) is not necessary in principle for exterior coatings, but is optionally possible.

[0107] 2k method example: Formulation of Ti plate coating with micromechanically fixed positions.

[0108] Pretreatment composition:

[0109] For the pretreatment composition, 1 molar calcium chloride solution was mixed with 0.1 molar TRIS buffer and the pH was adjusted to 9.0.

[0110] Compositions containing calcium ions:

[0111] (i) For Ca gel: 147g CaCl 2 *2H 2 O was dissolved with 47.5g lactic acid in 800ml water. The pH was adjusted to 10.5 with 106 ml of 5 N NaOH. To produce the gel 18 ml of this solution were mixed with 6 g of glycerol and 8 g of calcium sulfate and 13.6 g of 300 bloom gelatin and heated. The liquid gelatin is smoothed with a spatula to a thickness of 1 mm or pressed in a mold with a wall thickness of 1 mm. After curing the strips were c...

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Abstract

The invention relates to prosthetic moulded parts which comprise, at least in regions on the surface thereof, at least one layer of biomimetic apatite selected from fluorapatite, hydroxylapatite or mixtures thereof, wherein the surface of the moulded parts comprises, at least in said region, micromechanical anchoring locations for improving the mechanical binding of apatite on the surface. The invention also relates to moulded parts for use in dental prosthetic provision in the event of tooth loss, in particular, for cellular attachment of cells on prosthetic moulded parts. The invention further relates to the method for producing the prosthetic moulded parts.

Description

technical field [0001] The present invention relates to a prosthetic molding having at least partially on its surface at least one biomimetic apatite layer selected from fluorapatite, hydroxyapatite, or mixtures thereof, wherein the molding The surface of the article has micromechanical fixation sites for improving the mechanical bonding of the apatite to the surface, at least in this region. Likewise, the invention also relates to moldings for prosthetic fittings in the event of tooth loss, in particular for the attachment of cells, preferably via hemidesmosomes, to prosthetic moldings. Furthermore, the invention relates to a method for the production of the prosthetic molding. Background technique [0002] A problem with fixed, permanent tooth replacements such as graft-mounted restorations is that a gap is often left between the graft post and the surrounding gingiva. Because of this gap there is always an infection of the bone and surrounding soft tissue. This problem...

Claims

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Application Information

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IPC IPC(8): A61C8/00A61L27/54A61C8/02A61L27/32
CPCA61C8/0006A61L27/32A61L2400/18A61L2420/06A61L2430/02A61C8/0013A61C5/70A61C5/20A61C8/0016A61C8/0022A61C8/0074A61C13/09A61C13/24A61C13/26A61F2/30771A61F2002/2817A61F2002/3069A61F2002/30838
Inventor 马库斯·巴尔肯霍尔马库斯·霍夫曼安德烈亚·莱尔苏珊·布施
Owner 古萨有限公司
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