Implantable medical devices made from polymer-bioceramic composite
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Image
Examples
example 1
Prophetic Example of Solution Blending of Polymer and Bioceramic Particles
[0159] Step 1: Add bioceramic particles into suitable solvent, such as chloroform, acetone, etc. and stir to form a bioceramic particle suspension solution.
[0160] Step 2: Slowly add a polymer such as PLLA, PDLLA, PLGA into suspension solution and stir until polymer dissolves completely. In this step, the solution may still have a relatively low viscosity. However, the bioceramic particles should be well dispersed while stirring.
[0161] Step 3: Slowly add the polymer into solution again to gradually increase solution viscosity. Repeat this step as needed until the polymer is completely dissolved and reasonable solution viscosity is developed.
[0162] Step 4: Apply ultrasonic mixing to suspension solution for 15-30 min to further disperse all the HAP uniformly into the PLLA solution.
[0163] Step 6: Add suspension solution to methanol to precipitate polymer and particles.
example 2
[0164] Solution Blending of PLLA / HAP Composite (100:1 wt / wt)
[0165] Step 1: Added 50 mg HAP particles into 300 mL of chloroform and stirred for 10-30 minutes to form bioceramic particle suspension solution.
[0166] Step 2: Slowly added 5 g PLLA into suspension solution and stirred about 8 hours to dissolve all polymer.
[0167] Step 3: Applied ultrasonic mixing to suspension solution for 15-30 min to further disperse HAP particles into PLLA solution.
[0168] Step 4: Added suspension solution to 1 L methanol to precipitate polymer and particles.
[0169] Step 5: Filtered the precipitate and dried about 24 hours in vacuum oven at 60° C. End product is PLLA / HAP composite.
[0170] Composites were also made with 2 wt % and 5 wt % HAP.
[0171] Mechanical Properties and Morphology of PLLA / HAP Composite (100:1 wt / wt)
[0172] Tensile testing of the composite samples and a pure PLLA were performed using an Instron tensile tester obtained from Instron in Canton, Mass. Test samples were prepared by hot p...
example 3
[0174] Solution Blending of PLLA / HAP Composite (2:1 wt / wt) as HAP Intermedium Mixture
[0175] Step 1: Added 25 g HAP particles to 3 L chloroform and stirred for 10-30 minutes to form bioceramic particle suspension solution.
[0176] Step 2: Slowly added 50 g PLLA into suspension solution and stirred about 8 hours to dissolve all polymer.
[0177] Step 3: Applied ultrasonic mixing for 15-30 min to further disperse HAP particles into PLLA solution.
[0178] Step 4: Added suspension solution to 9 L methanol to precipitate particles and polymer.
[0179] Step 5: Filtered the precipitate and dried about 24 hours in vacuum oven at 60° C. End product is PLLA / HAP composite.
[0180] Extrusion of Precipitated PLLA / HAP (2:1 wt / wt) with PLLA
[0181] Step 1: Broke 2:1 wt / wt composite into small pieces
[0182] Step 2: Mixed 24 g of broken up composite and 376 g PLLA.
[0183] Step 3: Extruded mixture at 216° C.
PUM
Property | Measurement | Unit |
---|---|---|
Fraction | aaaaa | aaaaa |
Fraction | aaaaa | aaaaa |
Fraction | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com