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Freeze-drying protection system required for nucleic acid amplification reagent and preparation method of freeze-drying protection system

The invention belongs to the technical field of medicine preparation, and particularly relates to a freeze-drying protection system required for a nucleic acid amplification reagent and a preparationmethod of the freeze-drying protection system. The freeze-drying protection system comprises the nucleic acid amplification reagent and a freeze-drying protection additive, wherein the nucleic acid amplification reagent is a reagent used for LAMP reaction amplification, the freeze-drying protection additive is one or a compound of the following reagents: polyethylene glycol, mannitol, polyvinylpyrrolidone, glucan, trehalose, sucrose, bovine serum albumin, collagen, threonine and glycine, and the concentration of the weight-to-volume ratio of the freeze-drying protection additive and the amplification reaction reagent is 3% to 25%. The freeze-drying protection additive used in the invention has the advantages of small volume, short freeze-drying time, high efficiency and low energy consumption, and the freeze-drying protection system can be directly used for gene chip experiments, does not cause repeated freeze-thaw and waste of reagents, and can effectively ensure the activity of active substances in the freeze-drying process.
Owner:百康芯(天津)生物科技有限公司

Measuring transducer of vibration-type

The measuring transducer includes at least one measuring tube communicating with a line connected during operation for conveying a medium to be measured, and a support element oscillatably holding the at least one measuring tube. Additionally, it is provided that the support element contains at least two passageways, via which the at least one measuring tube communicates with the line, and that the at least one measuring tube is affixed, especially releasably, at at least one end to the support element by means of a screwed-fitting at one of the passageways. Alternatively or in supplementation thereof, it is further provided that the at least one measuring tube is, at least in part, made of cold-strengthened, for instance cold-stretched or autofrettaged, material. As required, the measuring transducer can further include at least two measuring tubes communicating with the line for conveying the medium; each of these two measuring tubes is to be connected to an inlet-side distributor element and an outlet-side distributor element. In such case, at least one of the two distributor elements can be embodied as an integral component of the support element, so that the support element can be kept, at least in the area of this at least one distributor element, free of materially bonded, joined locations, especially free of solder, braze or weld connections. The measuring transducer of the invention is especially provided also for applications in which the medium to be measured acts with a pressure of more than 500 bar, especially over 700 bar, on the measuring tube.
Owner:ENDRESS HAUSER FLOWTEC AG
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