The invention discloses a programmable electrical
interconnection neural information detection regulation and control
microsystem and method, and belongs to the technical field of
neuroscience and
biomedical engineering. The
system comprises a partitioned in-vitro neural
chip, an electrical stimulation module, a multi-channel neural
signal acquisition module, an electrical
interconnection control module and an upper
computer module. The partitioned in-vitro nerve
chip is manufactured based on an MEMS (Micro Electro
Mechanical System) process and supports partitioned culture of in-vitro
nerve cells; the electrical stimulation module can generate multi-channel nanoampere-to-
milliampere bidirectional constant-current pulses to realize accurate nerve regulation and control; the multi-channel neural
signal acquisition module is provided with a low-
noise amplifier array and is used for acquiring and converting multi-channel neural signals in real time; the electric
interconnection control module realizes dynamic
signal routing between partitions through the switch array; the upper
computer module provides parameter configuration,
signal processing and
visual interaction functions. The
system has the advantages of high integration level, high precision, programmability, real-time regulation and control and the like, and is suitable for in-vitro brain-computer interface and neural network function research.