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Medicinal or health care composition containing natural antimicrobials

A technology of natural antibacterial agent and composition, applied in the fields of health care and symptom prevention, can solve the problems of formula, formulation limitation, affecting the effective absorption of human body, etc.

Active Publication Date: 2008-05-21
GUANGXI HEBABIZ PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the high-efficiency antibacterial and antioxidant parts isolated from plants are water-insoluble substances, which cause restrictions on formulas and preparations, and affect the effective absorption of the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1, preparation method 1 of plant active part G007:

[0025] The plants include, but are not limited to, licorice, guava leaves, tea, Luo Han Guo, Radix Isatidis, Magnolia officinalis, bamboo leaves, white peony root, Houttuynia cordata, Aescin, vine tea, honeysuckle, chrysanthemum, Polygonum cuspidatum, and Jiujie tea. Take licorice as an example to describe below.

[0026] 100g of licorice, add 500ml of water, put it in a water bath at 85°C for 7h, let stand overnight, wash with warm water at 60°C for 3 times, 500ml each time, 5min each time; dry the washed licorice residue in an oven at 60°C; take the dried licorice residue and add 500ml of 95% ethanol or 100% methanol, reflux in a water bath at 85°C for 2.5h, filter out the first extract, rotatively evaporate, concentrate, and dry in an oven at 60°C to obtain the licorice extract of licorice, namely G007; Add 500ml of 95% ethanol or 100% methanol, reflux in 85°C water bath for 2h, filter out the second ex...

Embodiment 2

[0027] Embodiment 2, preparation method 2 of plant active part G007:

[0028] The plants include, but are not limited to, licorice, guava leaves, tea, Luo Han Guo, Radix Isatidis, Magnolia officinalis, bamboo leaves, white peony root, Houttuynia cordata, Aescin, vine tea, honeysuckle, chrysanthemum, Polygonum cuspidatum, and Jiujie tea. Take licorice as an example to describe below.

[0029] Weigh 100g of licorice, add 500-1000ml of water, keep warm at 15-85°C for 6-48 hours, wash 3 times with 500-1000ml of warm water, dry the washed licorice residue in an oven at 50-80°C; take the dried licorice residue and add Take 500ml of 95% ethanol or 100% methanol, extract or percolate at 20-85°C, filter the extract, rotovap, concentrate, and dry in an oven at 25-85°C to obtain licorice extract G007.

Embodiment 3

[0030] Embodiment 3, the preparation method 2 of guava leaf active part G007:

[0031] Weigh 100g of guava leaves, add 500-1000ml of water, keep warm at 15-85°C for 6-48 hours, wash 3 times with 500-1000ml of warm water, and dry the washed guava leaf residue in an oven at 50-80°C; Add 500ml of 95% ethanol or 100% methanol to the guava leaf residue, extract or percolate at 20-85°C, filter the extract, rotary evaporate, concentrate, and dry in an oven at 25-85°C to obtain guava leaf extract G007.

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PUM

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Abstract

The invention provides a medical or health-care compound and a preparation method. The compound contains at least one natural anti-bacterial agent which is separated for plants and is the soluble salt or ester formed through the extraction of the non-soluble anti-bacterial substance from plants. Further, the compound of the invention can also contain inflammation-diminishing, detumescence and anti-oxidation ingredients, as well as the preparation type auxiliary substances, Chinese medicine padding agent, etc, which are produced into a series of medicines or health-care medicines which restrain the anaerobic bacteria and effectively prevent the oxidation or aging of the human body cells. The compound of the invention can be produced into various forms, not only confined in the liquid form (for example the orally taken liquid), but also including spraying agent, liquid spraying agent, pills( e.g. buccal tablets), capsules, toothpaste, mouth clearing, etc. Moreover, the invention can be used for the health care for mouth, heart, gastrointestinal tract and joint or the treatment of the related diseases.

Description

technical field [0001] The invention belongs to the field of health care and prevention of symptoms of oral cavity, heart, gastrointestinal tract, joints, etc., and particularly relates to the preparation of a class of soluble salt (or ester) of natural antibacterial agents and the preparation and use of human products containing such soluble antibacterial agents method. Background technique [0002] The massive reproduction of anaerobic bacteria in the anaerobic state of the human body can cause various symptoms, including periodontitis, bad breath, gastritis, and even heart disease, gastroenteritis, and arthritis. Antibiotic therapy introduced in the West has a history of more than 50 years. Long-term use of antibiotics will lead to drug resistance, because pathogenic microorganisms will produce genetic factor mutations to form drug-resistant strains. [0003] When the human body is in the state of a large number of anaerobic bacteria, the oxidation or aging of cell tiss...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K36/82A61K36/78A61K36/71A61K36/704A61K36/61A61K36/484A61K36/424A61K36/42A61K36/35A61K36/315A61K36/28A61K36/19A61K47/02A61K47/46A61P31/04A61K8/97A61K31/122A61K31/375A61K31/60A61K33/08A61K33/22A61Q11/00
Inventor 詹姆斯·周
Owner GUANGXI HEBABIZ PHARM TECH CO LTD
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