93 results about "Blood gas test" patented technology

The invention provides an intermittent detection method and device for body fluid parameters and a related system.The method is applied to a body fluid parameter detection system, the system comprises an infusion tube, a detection module, an extraction and injection device, a liquid path switch and a flushing device.The method comprises the steps that the liquid path switch is controlled to execute a closing action, and the liquid path switch is controlled to close the infusion tube; controlling the extraction and injection device to extract a preset first volume of target body fluid from a preformed hole of a target user into the infusion tube, controlling the detection module to detect parameters of the target body fluid when the target body fluid in the infusion tube is detected to pass through the detection module, obtaining the parameters of the target body fluid, controlling the liquid path switch to execute an opening action, and controlling the liquid path switch to execute a closing action; and controlling the flushing device to inject a preset second volume of functional liquid into the infusion tube, and controlling the extraction and injection device to enable the target body fluid to flow back to the target user when the functional liquid in the infusion tube is detected to pass through the detection module. When blood gas parameter detection is carried out, blood waste and detection cost are reduced.

The invention relates to the technical field of human body blood gas monitoring, and discloses a blood gas monitoring method and system of an extracorporeal circulation system.The method comprises the steps that current blood gas data of a patient is collected, cleaning is conducted, blood gas features are extracted, the features are input into a blood gas prediction model, and the change trend of the blood gas data of the patient in the future effective intervention period is predicted; if it is monitored that the blood gas data of the patient tends to be bad in the time period, parameters of the oxygenator are actively adjusted; meanwhile, according to the basic information of the patient and the current blood gas data, a corresponding oxygenation parameter adjustment strategy is screened, the change trend of the blood gas data of the patient is continuously predicted, and whether the oxygenation parameter adjustment strategy is replaced or not is judged according to the updated prediction result until the predicted blood gas data of the patient is in a good change trend; the technical problem that existing blood gas monitoring lacks effective early warning is solved.

The invention discloses a treatment guidance system for a hyperkalemia patient, and the system comprises a data detection unit which obtains the medical history, symptom signs and inspection data of the patient through the butt joint of a hospital information system and a laboratory information system, and carries out the data cleaning and structural processing; the decision analysis unit is used for generating a first treatment scheme based on a pre-stored treatment guide rule base and the real-time data; the scheme guidance unit is used for generating a second treatment scheme according to the feedback of the auditing end and pushing the second treatment scheme to the execution end; the dynamic monitoring unit is used for monitoring indexes such as blood potassium, blood gas, electrocardiogram, blood sugar and urine volume of the patient in real time and triggering treatment adjustment and reexamination reminding according to a preset rule; and the long-term management unit is used for generating a personalized long-term management scheme in combination with etiological analysis. According to the invention, through standardized treatment process, intelligent dose correction, dynamic risk early warning and multi-department cooperation, precise, continuous and closed-loop management of hyperkalemia treatment is realized, the short-term death rate is reduced, and the long-term prognosis of a patient is improved.

The invention discloses a transient sensing device for detecting carbon dioxide concentration through a percutaneous patch, and belongs to the technical field of percutaneous blood gas detection.The transient sensing device comprises a collecting main body, an annular adhering part and a gas collecting assembly, the collecting main body is provided with a cylindrical shell, a butt joint ring and a display screen, the annular adhering part is connected with the butt joint ring through a magnetic suction rod, and an annular medical silica gel pad is arranged; an inflation part is arranged in a butt joint hole in the butt joint ring and communicates with the annular elastic air bag to form a flexible annular sealing structure, the air tightness is improved, the gas production assembly comprises a gas production cover, a gas pump, a gas sensor and the like, and a high-precision laser spectrum sensor is adopted for detecting the concentration of carbon dioxide. A buffer chamber, a pressure controller, a flow controller and the like are arranged to guarantee stability and accuracy of a gas sample, the device is further provided with a gas distribution core, an electric heating net, a flow guide cover and the like to optimize gas distribution and temperature control, accurate, stable and continuous monitoring of the carbon dioxide concentration is achieved, meanwhile, the comfort and safety of a user are guaranteed, and the device is suitable for clinical diagnosis and treatment.

The present invention relates to methods for determining a blood gas parameter and / or a basic metabolic panel parameter in a blood sample comprising combining the blood sample with an anti-coagulant and an anti-platelet agent, and determining said blood gas parameter and / or parameter in the sample. In some aspects, the invention relates to determining said parameters in samples that have been subjected to pre-analytical stress.

The invention relates to a blood gas biochemical test card and blood gas analysis equipment. The detection assembly comprises a first clamping piece, a second clamping piece and a ring body, and the first clamping piece is provided with a first surface; the second clamping piece is provided with a second surface, and the second surface is provided with a plurality of detection electrodes; the ring body is clamped between the first surface of the first clamping piece and the second surface of the second clamping piece, so that an accommodating space is formed on the inner side of the ring body; the first clamping piece and / or the second clamping piece are / is provided with a liquid inlet and a liquid outlet, and the liquid inlet, the containing space and the liquid outlet are communicated. According to the detection assembly, the containing space is formed in the inner side of the ring body, and the liquid inlet and the liquid outlet which are communicated with the containing space are formed in the first clamping piece and / or the second clamping piece, so that the detection assembly can achieve multiple times of repeated measurement, the measurement frequency is increased, in addition, the detection assembly can be repeatedly used, and the detection cost is reduced. And the cost of consumables can be saved to a certain extent.

The invention relates to the technical field of biological medicines, in particular to a pharmaceutical composition and application thereof in preparation of a medicine for treating the heart-lung qi deficiency type pulmonary heart disease. The pharmaceutical composition consists of 21-27 parts of astragalus membranaceus, 13-17 parts of semen lepidii, 7-10 parts of cassia twig, 21-27 parts of ligusticum wallichii, 7-10 parts of rhizoma alismatis, 5-7 parts of platycodon grandiflorum and 2-4 parts of Chinese dates. Compared with the prior art, the cassia twig is adopted to replace fructus psoraleae in an original formula, and meanwhile, the medicinal material specifications of the fried semen descurainiae, the raw ligusticum wallichii and the salted rhizoma alismatis are preferably selected. The invention also provides three preparation methods of the pharmaceutical composition, namely a water extraction and alcohol precipitation method, an alcohol extraction and water extraction combined method and a crushing and mixing method. Experimental results show that the pharmaceutical composition has remarkable effects on improving heart functions, lung functions, blood-gas indexes, right ventricular hypertrophy and the like of pulmonary heart disease model animals, meanwhile, the hepatotoxicity risk of fructus psoraleae is avoided, and the pharmaceutical composition has a good clinical application prospect.

The utility model provides a kind of mixing device of arterial blood collector, including rotating shaft and the mixing assembly being fixed in its outside, and the side plate of polygon is respectively arranged in the two sides of rotating shaft and multiple bearing plates are fixed on side plate, the detachable blood gas needle loading plate is equipped on the bearing plate, and multiple detachable blood gas needle mounting clips are equipped on the blood gas needle loading plate;The blood gas needle mounting clip is detachably set on the bearing plate.By blood gas needle mounting clip detachably set on blood gas needle loading plate, and blood gas needle loading plate itself also detachably install in the design of bearing plate, effectively solve the core pain point of poor versatility of traditional mixing device.

The sensors (4) can be used to detect the concentration of an analyte, such as an electrolyte and / or a blood gas. In some models, these sensors may include a matrix material, a nanoparticle (2) associated with the matrix material, and a signaling molecule (10, 12, 14, 16) associated with the nanoparticle. In some cases, the signaling molecule may exhibit a fluorescence emission intensity (20, 22, 24, 26) as a function of the analyte concentration. Abbreviated figure: Fig. 2.

The invention relates to the technical field of intelligent medical treatment, particularly provides a blood gas index data prediction method, a computer readable storage medium and intelligent equipment, and aims to solve the problem that blood gas index time sequence data is inconvenient to obtain due to small data volume of existing blood gas index data. In order to achieve the purpose, the blood gas index data prediction method comprises the steps of obtaining actually measured blood gas index data at a first moment and first physical sign index time sequence data from the first moment to a first target moment; and with the actually measured blood gas index data as a hidden state and the first sign index time sequence data as input, predicting first predicted blood gas index data at the first target moment by using a pre-trained neural network model. By combining the physical sign index time sequence data associated with the blood gas index data, the blood gas index data at different moments can be effectively predicted by using the pre-trained neural network model, and the problems that the data volume of the actually measured blood gas index data is small and the blood gas index time sequence data is inconvenient to obtain are solved.

A blood gas analyzer (1) for measuring an analyte parameter in a blood sample, such as a whole blood sample, aspirated from a handheld blood sample container (100) into the blood gas analyzer (1) comprises a controller (8) and a sensor system (5) for detecting the presence, position and / or orientation of the handheld blood sample container (100) relative to an inlet structure (12a / b). An aspiration system is provided for aspirating the blood sample from the handheld blood sample container (100), which aspiration system can be connected to the handheld blood sample container (100). A user interface system is provided for outputting instructions to a user (102) of the blood gas analyzer (1), the instructions being selected from a set of pre-stored instructions. The controller (8) selects one of the at least two sets of pre-stored instructions based on an evaluation of signals obtained from the sensor system.

According to the technical scheme, the multi-tube blood test specimen mixer comprises a main body and a touch control box, a movable ball is installed at the bottom in the main body, an overturning base is installed at the top of the movable ball through a connecting rod, a supporting base is installed at the position, close to the outer surface, of the top of the overturning base, and a rotating disc is installed at the top of the supporting base through a steel ball A; rotating shafts are installed at the four corners in the rotating disc, a uniform mixing seat is installed at the tops of the rotating shafts, a supporting frame is installed in the middle of the top in the main body, and a high-speed camera is installed on the outer surface of the supporting frame. The multi-tube blood test sample mixer solves the problems that after an existing blood gas analysis sample is uniformly mixed, a corresponding blood gas sample needs to be manually searched in multiple tubes through naked eyes and taken out, the operation is tedious, and the use convenience is not high, the blood gas sample taking-out efficiency is improved, and the working efficiency is improved. Meanwhile, the detection efficiency of the blood-gas mixer is improved.

Electrochemical sensor modules for blood gas analyzers are disclosed that can detect the presence of a blood micro clot or deposit on a pH sensor. The electrochemical sensor modules include an integrated sensor chip containing a pH sensor and a bicarbonate (HCO3) sensor. Kits and systems containing the electrochemical sensor modules are also disclosed, as well as methods of using the electrochemical sensor modules.

The present application relates to a kind of blood gas analyzers, including test card assembly and reagent pack assembly, test card assembly at least includes the test card main body with calibration liquid port, reagent pack assembly at least includes rotating switch assembly, liquid storage device, air inlet device and sample inlet device with liquid inlet needle, rotating switch assembly includes the fixed valve body with first pipe mouth with liquid storage device communication, second pipe mouth with sample inlet device communication, third pipe mouth with air inlet device communication, and rotating main body with communication pipeline is set, both ends of liquid inlet needle are respectively communicated with second pipe mouth and calibration liquid port, rotating main body is set in fixed valve body inside and can be rotated relative to fixed valve body to realize first pipe mouth and second pipe mouth communication, or second pipe mouth and third pipe mouth communication, or close second pipe mouth.This blood gas analyzer uses rotating switch assembly to realize the on-off control of different pipeline, without pressing and relaxing rubber tube action, there is no pipeline blockage hidden trouble, prevent calibration liquid from leaking.

A method for controlling carbon dioxide [CO2] removal in a device (5) for extracorporeal blood gas exchange is disclosed. The device (5) comprises an oxygenator (21) including a membrane (23) acting as a gas-liquid barrier enabling CO2 transfer between a bloodstream and a sweep gas flow through the oxygenator. The method comprises the steps of adding (S1) CO2 to the sweep gas flow upstream of the oxygenator (21) to control a degree of CO2 removal from the bloodstream by the oxygenator, determining (S2) a measure of CO2 removal by the oxygenator (21) based on a difference [ΔCCO2blood] between a measure of a pre-oxygenator content of CO2 [CCO2in] in the bloodstream upstream of the oxygenator (21) and an estimate of a post-oxygenator content of CO2 [CCO2out] in the bloodstream downstream of the oxygenator (21), and utilizing (S3) the measure of CO2 removal for improved regulation of the CO2 addition to the sweep gas flow.

The present invention provides a method for judging temperature abnormality and a method for data correction of a blood gas biochemical analyzer. According to a plurality of ambient temperatures and a plurality of heating element temperatures, a plurality of ambient temperature filtering results and heating element temperature filtering results are obtained; if each heating element temperature filtering result meets the heating element threshold temperature, and the air duct temperature at the currently obtained time belongs to the air duct threshold temperature range, it is confirmed that the temperature control state of the blood gas biochemical analyzer is in a normal state. In this way, according to the ambient temperatures and heating element temperatures corresponding to a plurality of time points respectively, a plurality of ambient temperature filtering results and a plurality of heating element temperature filtering results can be obtained. As long as each heating element temperature filtering result meets the heating element threshold temperature under the corresponding ambient temperature filtering result, and the air duct temperature corresponding to the current time also meets the air duct threshold temperature range, it can ensure that the temperature control state of the blood gas biochemical analyzer is in a normal state, thereby improving the accuracy of subsequent measurement data.

The present invention relates to method for providing values of measured and / or estimated arterial oxygenation (SO2AM, SO2AE, SpO2) based on measuring values of blood acid / base status in a venous blood sample (VBGM, VBGE). A conversion of the venous blood values is made by applying a mathematical model for deriving blood acid / base status and oxygenation status into estimated or predicted arterial blood values (ABGP). Furthermore, if a value of measured and / or estimated arterial oxygenation value is below a corresponding venous oxygenation value, then estimating the arterial oxygenation value is made with a replacement value being a function of the corresponding venous oxygenation value. The advantage is that converting venous blood value to arterial blood values will be possible by providing arterialized blood gas and acid-base values for a higher percentage of clinical samples previously not possible.

A wearable, skin adhesive blood gas monitoring device detects both oxygen and carbon dioxide for accommodating a potential inaccuracy in an oxygen level resulting from excessive carbon dioxide. Photoluminescent films in conjunction with a compact form-factor circuit provide a wearable and unobtrusive device that adheres directly to the epidermal surface for computation of blood gas levels based on transcutaneous and reflective properties of the blood gases. A wireless medium such as Bluetooth® enables communication to a standalone or portable device such as a smartphone or similar personal device having an application (app) for receiving the computed signals. Conditions such as hypercarbia, which tend to result in higher levels of carbaminohemoglobin, or hemoglobin bound to CO2 instead of oxygen, tend to compromise computed oxygen levels by interpreting the CO2-bound hemoglobin as oxygenated blood.

The present application relates to medical detection technical field, especially to a blood gas detection reagent card, comprising a detection box, a calibration liquid module and an electrode reaction card, the inside of the detection box is provided with a reaction cavity, a calibration liquid flow channel and a sample inlet channel, the calibration liquid flow channel and the sample inlet channel are both communicated with the reaction cavity, when the content of each corresponding component in the sample is detected, the calibration liquid module supplies the calibration liquid to the calibration liquid flow channel, the calibration liquid flows to the reaction cavity along the calibration liquid flow channel, and the electrode reaction card is calibrated, the surface of the detection box is provided with a sample inlet, after the blood sample is supplied into the sample inlet, the blood sample enters the reaction cavity through the sample inlet channel and contacts with the electrode reaction card in the reaction cavity, so that the content of each corresponding component in the sample can be detected, through the setting of the electrode reaction card, the calibration liquid module, the calibration liquid flow channel and the sample inlet channel, the blood sample detection process can be concentrated in the detection box, thereby effectively reducing the volume of the equipment, facilitating the carrying of the blood gas detection equipment, and facilitating the content detection of each corresponding component in the sample.

1. The name of the design product: blood gas analyzer. 2. The use of the design product: the design product is used for blood gas, blood oxygen, electrolyte and metabolite analysis. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The application discloses a method and a kit for immunodetection of target substances by using arterial blood, and belongs to the technical field of blood detection. The kit comprises at least: a first component containing luminescent microspheres combined with detection antibody 1 and a luminescent microsphere diluent, wherein the luminescent microsphere diluent contains 2-morpholinoethanesulfonic acid, KCl and NaHCO3; a second component containing biotin-labeled detection antibody 2 and a biotin diluent, wherein the biotin diluent contains dithiothreitol, CaCl2, adenine nucleoside and mouse anti-human hemoglobin antibody; and a third component containing photosensitive microspheres combined with streptomycin. The scheme can be used for immunodetection of target substances by using arterial blood, has excellent functional sensitivity and detection range, is not interfered by other substances in arterial blood, realizes rapid detection of all blood gas indexes and immunological indexes by using one tube of arterial blood, and has important significance for clinical blood detection.

The application discloses a kind of local brain tissue blood oxygen saturation near-infrared detection method and device, to solve the problem of the difference between the group average head model parameter and patient individual parameter in prior art, especially severe patients;Existing device also has the problems of positioning deviation, poor repeatability, insufficient accuracy and difficult to quantify indicators. Through the accurate and repeatable positioning of skin texture double-mode positioning sticker, the individual head three-dimensional anatomical model and individual multi-layer light transmission simulation model are constructed by querying the patient individual image data, and the light transmission loss is calculated layer by layer, combined with the patient individual skull density, based on the patient individual image head blood flow map analysis of cerebral blood perfusion process and individual neck arteriovenous biochemical blood gas detection, to complete the individualized detection of local brain tissue blood oxygen saturation. The application calls the existing multi-source detection data of the patient to improve the detection accuracy of local brain tissue oxygen saturation by algorithm calculation, without any additional examination and cost.

A demand-adapting and auto-regulatory ECMO system and method is disclosed that may be configured to provide complete cardiopulmonary replacement. The system and method employ a blood gas exchanger having a blood inlet, a blood outlet, a gas inlet, and a gas outlet, an oxygen sensor positioned to detect oxyhemoglobin saturation at the blood inlet, and a carbon dioxide sensor positioned to detect exhaust gas CO2 concentration at the gas outlet. A controller communicates with the oxygen sensor and the carbon dioxide sensor and controls blood flow and gas flow through the blood gas exchanger in response to a sensed oxygen level by the oxygen sensor and a sensed carbon dioxide level by the carbon dioxide sensor, in turn maintaining the sensed oxygen level and the sensed carbon dioxide level within a pre-designated range of values to maintain a patient's metabolic requirements.

The utility model relates to the technical field of diagnostic instruments, and discloses a portable blood gas biochemical analyzer with an anti-drop circuit, which comprises an analyzer body, the upper surface of the analyzer body is fixedly connected with a connector I, the inner wall of the connector I is connected with a connector II in a sliding manner, and the inner wall of the connector II is provided with a limiting component; the limiting assembly comprises a clamping ball, the outer wall of the clamping ball is slidably connected to the inner wall of the second connector, the outer wall of the second connector is fixedly connected with a partition plate, the outer wall of the partition plate is fixedly connected with a sliding rod, one end of the sliding rod is fixedly connected with a first handle, the outer wall of the sliding rod is sleeved with a spring, and a sliding groove is formed in the first connector. According to the utility model, through the sliding fit of the first connector and the second connector and the combination of the clamping ball and the spring structure of the limiting assembly, the rapid plugging is realized, the mechanical locking is ensured at the same time, the circuit is effectively prevented from accidentally falling off due to vibration or external force pulling, and the use convenience is improved.

A monitoring apparatus is to be applied to an assisted circulation apparatus, the assisted circulation apparatus being connected to a living body, transferring blood removed from the living body to a membrane lung by a blood transfer pump, and gas-exchanging and oxygenating the blood in the membrane lung in parallel with a native lung, and the monitoring apparatus includes a calculation unit that calculates a blood gas-exchanging state index indicating a gas-exchanging state of blood by the assisted circulation apparatus.

This invention discloses a fully automated chemiluminescence immunoassay blood gas analyzer, belonging to the field of blood testing technology. The analyzer includes a sample loading module, a mixing module, and a blood gas module. The sample loading module includes a sample tray with a locking slot for holding a blood collection needle. The mixing module includes a first longitudinal displacement module, a first lifting displacement module, a first rotation module, and grippers. The grippers can grasp the blood collection needle within the locking slot. The first longitudinal displacement module and the first lifting displacement module can move the blood collection needle within a first plane. The first rotation module can shake the blood collection needle via the grippers. The blood gas module has an extendable blood gas sampling needle located within the first plane. Compared with existing technologies, the fully automated chemiluminescence immunoassay blood gas analyzer provided by this invention integrates the functions of both chemiluminescence and immunoassay blood gas analyzers. Only one blood sample is needed to complete both types of tests, reducing the burden on patients, decreasing consumable consumption, and simplifying the testing operation.

Computer system and computer-implemented method for rendering representations of blood gas state parameters of a patient to support a medically trained person in blood gas analysis of the patient's blood, comprising: receiving, from a data source, time series of sampled measurement values obtained from a plurality of blood gas analysis sensors for the following blood gas state parameters of the patient: Glucose, Chloride, Potassium, Calcium, Sodium, and Hemoglobin; mapping each state parameter to a predefined corresponding graphical representation with each graphical representation for a particular state parameter being distinct from all graphical representations of the remaining state parameters; and rendering, in a virtual 3D tunnel shaped scene representing the inside of an artery, animated visualizations of the graphical representations, in accordance with predefined animation rules, such that respective graphical objects move through the inside of the artery and reflect current values of the respective state parameters.

A blood gas specimen transportation device comprises a container body used for storing refrigerating fluid, a plurality of storage tubes are inserted into the container body, at least part of each storage tube is located in the refrigerating fluid, and a detachable sealing plug is arranged at the opening of each storage tube; the container body is further provided with a handle and further comprises a timer used for recording the transportation duration. Most of the storage pipe is located in the refrigerating fluid which can be frozen into ice blocks, and the refrigerating effect is good; a storage tube is arranged to facilitate the storage of the blood gas specimen; a sealing plug is arranged, so that the blood-gas specimens are prevented from falling off and being lost in the inspection process, and ice water is prevented from shaking to enter the storage tube from the tube opening of the storage tube in the transportation process after ice blocks are melted to pollute the blood-gas specimens; the timer is used for reminding transportation personnel to control the transportation time, so that timeout is avoided; the transportation device is simple in structure and low in cost, the blood-gas specimens cannot be exposed to high temperature for a long time, and the situation of inaccurate detection is effectively reduced.

The invention discloses a full-automatic light-emitting immune blood gas analyzer, and belongs to the technical field of blood detection.The analyzer comprises a sample loading module, a shake-up module and a blood gas module, the sample loading module comprises a sample disc, and the sample disc is provided with a bayonet used for being connected with a blood taking needle in a clamped mode; the shaking module comprises a first longitudinal displacement module, a first lifting displacement module, a first rotating module and a clamping jaw, the clamping jaw can clamp the blood taking needle in the bayonet, the first longitudinal displacement module and the first lifting displacement module can drive the blood taking needle to move in a first plane, and the first rotating module can shake the blood taking needle through the clamping jaw; the blood gas module is provided with a blood gas sampling needle capable of stretching out, and the blood gas sampling needle is located in a first plane. Compared with the prior art, the full-automatic light-emitting immune blood gas analyzer provided by the invention integrates the functions of a light-emitting immune blood gas analyzer and an immune blood gas analyzer, and two types of detection can be completed only by collecting one blood sample, so that the burden of a patient is relieved, the consumption of consumables is reduced, and the detection operation is simplified.