The invention discloses a non-intubation general anesthesia pulmonary lobectomy system based on robot assistance, and particularly relates to the technical field of operation anesthesia. The non-intubation general anesthesia pulmonary lobectomy system comprises a human body, a nerve block set or an epidural puncture bag, and a laryngeal mask; and the human body is connected with an ultrasonic instrument used for guiding lower thoracic paravertebral nerve block or thoracic epidural block, a BIS monitor used for monitoring the sedation depth of a patient, an invasive arterial monitor used for monitoring arterial blood gas of the patient, and a conventional monitor used for monitoring vital signs of the patient. Through thoracic paravertebral nerve block or epidural block, good unilateral orbilateral analgesia can be provided, sympathetic nerve tension is lowered, the dosage of general anesthetics, especially opioids is decreased, complications of trachea intubation general anesthesia ofthe patient of pulmonary lobectomy under assistance of a Da Vinci robot are reduced, the patient can fall asleep through general anesthesia, trachea intubation is replaced with the laryngeal mask, the postoperation satisfaction of the patient with general anesthesia is better, and postoperative rehabilitation of the patient of the chest department is promoted.