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55results about How to "Substantial risk" patented technology

System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure

A method and apparatus for the transcutaneous monitoring of blood gases generally comprises a blood gas data acquisition device, a vacuum source and a blood gas transducer unit. The blood gas transducer unit is adapted for application to a patient's skin and administration of a local vacuum at the area of patient application. It further comprises an electrochemical blood gas transducer, well known to those of ordinary skill in the art, which is disposed entirely within the local vacuum at the area of patient application. The vacuum source is placed in fluid communication with the blood gas transducer unit, through a hydrophobic membrane filter for safety purposes, in order to induce a condition of hyperperfusion in the locality of the electrochemical blood gas transducer. Under the control of a microcontroller, or equivalent means, the blood gas acquisition device is then utilized to capture a measure of skin surface oxygen or carbon dioxide pressure. The microcontroller can then utilize this measure to arrive at an estimate of arterial partial pressure of oxygen or carbon dioxide, accordingly. Because vacuum induced perfusion produces the requisite condition of hyperperfusion without local heating and, therefore, without acceleration of the local metabolic function, the present invention results in more accurate than previously available estimates of partial pressure blood gas pressures and does so while eliminating a significant risk for injury to the patient.
Owner:KCI LICENSING INC

Centralized hospital monitoring system for automatically detecting upper airway instability and for preventing and aborting adverse drug reactions

A system and method for the automatic diagnosis of obstructive sleep apnea in a centralized hospital critical care monitoring system for the monitoring of a plurality of patients in at least one of a critical care, step down, and cardiac ward by telemetry. The system includes a central processor having a display, and a plurality of telemetry units for mounting with patients, each of the telemetry units has a plurality of sensors for connection with each patient, the telemetry unit is capable of the transmission of multiple signals derived from the sensors to the central processor, in one preferred embodiment the method comprising steps of programming the system to analyze the signals and to automatically identify the presence and severity of obstructive sleep apnea and to provide an indication of the identification.
Owner:LYNN LAWRENCE A +1

Method for genetic testing of human embryos for chromosome abnormalities, segregating genetic disorders with or without a known mutation and mitochondrial disorders following in vitro fertilization (IVF), embryo culture and embryo biopsy

We describe a method for interrogating the content and primary structure of DNA by microarray analyses and to provide comprehensive genetic screening and diagnostics prior to embryo transfer within an IVF setting. We will accomplish this by the following claims: 1) an optimized embryo grading system, 2) a less invasive embryo biopsy with reduced cellular contamination, 3) an optimized DNA amplification protocol for single cells, 4) identify aneuploidy and structural chromosome abnormalities using microarrays, 5) identifying sub-telomeric chromosome rearrangements, 6) a modified DNA fingerprinting protocol, 7) determine imprinting and epigenetic changes in developing embryos, 8) performing genome-wide scans to clarify / diagnose multi-factorial genetic disease and to determine genotype / haplotype patterns that may predict future disease, 9) determining single gene disorders with or without a known DNA mutation, 10) determining mtDNA mutations and / or the combination of mtDNA and genomic (nuclear) DNA aberrations that cause genetic disease.
Owner:KEARNS WILLIAM G +1

Subsonic aircraft with backswept wings and movable wing tip winglets

InactiveUS6345790B1Optimized aerodynamic streamline contourRaise the ratioInfluencers by generating vorticesAircraft stabilisationWingspanAirplane
A subsonic aircraft having backswept lifting wings is equipped with individually rotatable winglets at the wing tips thereof, in order to reduce drag during cruise flight, to minimize the dangers posed by wing tip vortices to following aircraft during take-off and landing, and to minimize the total wingspan during ground operations, with respective different positions of the winglets. A streamline-shaped rotation body made up of at least two individually rotatably supported rotation segments is mounted on the wing tip of each lifting wing. A respective winglet is mounted on each respective rotation segment. Each rotation segment with its associated winglet is individually rotatable about a rotation axis of the rotation body extending substantially parallel to the aircraft lengthwise axis. Thereby, each winglet is individually pivotable to any selected pivot angle relative to a horizontal plane extending through the rotation axis. Each winglet and its associated rotation segment is rotatable through an angular range between maximum end limits of at least +90° (vertically upward) and at least -90° (vertically downward) relative to the horizontal plane.
Owner:DAIMLER CHRYSLER AEROSPACE AIRBUS

Centralized hospital monitoring system for automatically detecting upper airway instability and for preventing and aborting adverse drug reactions

A system and method for the automatic diagnosis of obstructive sleep apnea in a centralized hospital critical care monitoring system for the monitoring of a plurality of patients in at least one of a critical care, step down, and cardiac ward by telemetry. The system includes a central processor having a display, and a plurality of telemetry unit for mounting with patients, each of the telemetry units has a plurality of sensors for connection with each patient, the telemetry unit is capable of the transmission of multiple signals derived from the sensors to the central processor, in one preferred embodiment the method comprising steps of programming the system to analyze the signals and to automatically identify the presence and severity of obstructive sleep apnea and to provide an indication of the identification.
Owner:LYNN LAWRENCE A +1

System for combined transcutaneous blood gas monitoring and negative pressure wound treatment

A method and apparatus for the transcutaneous monitoring of blood gases generally comprises a blood gas data acquisition device, a vacuum source and a blood gas transducer unit. The blood gas transducer unit is adapted for application to a patient's skin and administration of a local vacuum at the area of patient application. It further comprises an electrochemical blood gas transducer, well known to those of ordinary skill in the art, which is disposed entirely within the local vacuum at the area of patient application. The vacuum source is placed in fluid communication with the blood gas transducer unit, through a hydrophobic membrane filter for safety purposes, in order to induce a condition of hyperperfusion in the locality of the electrochemical blood gas transducer. Under the control of a microcontroller, or equivalent means, the blood gas acquisition device is then utilized to capture a measure of skin surface oxygen or carbon dioxide pressure. The microcontroller can then utilize this measure to arrive at an estimate of arterial partial pressure of oxygen or carbon dioxide, accordingly. Because vacuum induced perfusion produces the requisite condition of hyperperfusion without local heating and, therefore, without acceleration of the local metabolic function, the present invention results in more accurate than previously available estimates of partial pressure blood gas pressures and does so while eliminating a significant risk for injury to the patient.
Owner:KCI LICENSING INC

Multi-position locking mechanisms for clamping assemblies

InactiveUS7314331B1Easily sterilizeReadily adjustFurniture joining partsScaffold connectionsBearing surfaceCam
A locking mechanism for a clamping assembly includes a roller locking mechanism, at least one clamping member and a shaft member for coupling the roller locking mechanism with the first clamping member. The roller mechanism includes a roller rotatably connected to a handle which contacts a bearing surface to place a compressive force on the first clamping member when the handle is actuated. Another locking mechanism includes a camming member having cam face with a sliding cam surface and a frictional cam surface adjacent to the sliding cam surface. The camming member produces a compressive force on the clamping member as the sliding cam surface contacts a bearing surface and increased static friction when the frictional cam surface contacts the bearing surface to help maintain the camming member in a locked position. Another locking mechanism includes a support frame, a camming member pivotally attached to the support frame, a clamping member and a shaft member for coupling the roller locking mechanism with the first clamping member, the shaft member including a sliding pin which remains in sliding engagement with the camming member.
Owner:KOROS TIBOR +1

Hybrid securities having protection against event risk using uncorrelated last-to-default baskets

Hybrid securities defined as last-to-default credit default swaps over multiple name baskets and having protection against event risk. In the preferred embodiment, the hybrid security is defined as a second-to-default credit default swap over a two-name basket, wherein the underlying reference obligors in the basket are uncorrelated or substantially uncorrelated. A portfolio of second-to-default swaps over two-name baskets is provided, wherein the portfolio is defined in a manner that further reduces default risk through enhanced diversification achieved by recombining underlying reference obligors in different second-to-default baskets. A structured investment in a portfolio of underlying second-to-default swaps over two-name baskets is provided using a collateralized debt obligation (CDO) structure.
Owner:BABCOCK & BROWN

Set for installing an intracardiac stimulation or defibrillation lead equipped with a screw

A set for installing an intracardiac lead equipped with a screw in a wall of the endocardium, particularly a stimulation or defibrillation lead. This set comprises a removable stylet (50), able to be introduced inside the sheath (12) of the lead-body and mobile in translation and rotation therein. The stylet has at its distal extremity a mechanism (56) for coupling in rotation to allow the rotation (28) of the lead-head (10). The stylet (50) includes: a central core (52, 71) carrying at its distal extremity the aforementioned coupling mechanism, and at its proximal extremity a handling body (32) for handling by the physician and a hollow tube (54) axially placed around the core. The length of the hollow tube is less than the length of the core, so that the latter emerges from the hollow tube at the proximal and distal extremities of the tube, so as to allow the rotation of the core and correlatively of the coupling mechanism, by action on the handling body, primarily without setting in rotation of the hollow tube.
Owner:SORIN CRM

Centralized hospital monitoring system for automatically detecting upper airway instability and for preventing and aborting adverse drug reactions

InactiveUS20120330118A1Improve instabilityVigilance of hospital personnel may diminishDrug and medicationsSensorsAdverse drug reactionInstability
A system and method for the automatic diagnosis of obstructive sleep apnea in a centralized hospital critical care monitoring system for the monitoring of a plurality of patients in at least one of a critical care, step down, and cardiac ward by telemetry. The system includes a central processor having a display, and a plurality of telemetry units for mounting with patients, each of the telemetry units has a plurality of sensors for connection with each patient, the telemetry unit is capable of the transmission of multiple signals derived from the sensors to the central processor, in one preferred embodiment the method comprising steps of programming the system to analyze the signals and to automatically identify the presence and severity of obstructive sleep apnea and to provide an indication of the identification.
Owner:LYNN LAWRENCE A

Lottery ticket with taggant detection of scratchoff

InactiveUS20080122220A1Accurate detectionAvoiding and at least reducing possibility of fraudOther printing matterBoard gamesEngineeringData Applied
A lottery ticket has a covering scratch-off coating applied over at least part of a game area, including game data applied over an ink layer including a lily pad. A detectable taggant additive material is admixed in an ink of the ink layer having the characteristic of being detectable by a detection scanner when applied over the substrate where the covering scratch-off coating masks the ability of the detection scanner to detect the detectable taggant additive material through the covering scratch-off coating. The scanning of the game area is used to detect areas where the scratch is removed in order to confirm that the game has been played or to detect patterns of removal in a probability type game.
Owner:POLLARD BANKNOTE PARTNERSHIP

Electric pump

To provide an electric pump that does not easily suffer malfunction of its driver due to vibration and whose components can be reduced in number, an electric pump includes a pump unit, a motor unit for driving the pump unit, and a driver chamber having a driver for controlling the pump unit. At least a space inside the driver chamber on one side of a substrate of the driver is filled with an amount of potting material for anchoring the substrate, whereas a space inside the driver chamber on the other side of the substrate is left as an unfilled space free from filling with potting material along the face direction of the substrate.
Owner:AISIN SEIKI KK

Method and apparatus for performing cementing operations on top drive rigs.

ActiveUS20110048710A1Quickly and efficiently separateEasily and efficiently and disconnectedDrilling rodsFluid removalTop driveWell drilling
A remotely operated lifting top drive cement head is provided having a high tensile strength, as well as the ability to swivel or rotate about a central vertical axis. The cement head permits selective launching of darts, setting plugs, balls or other objects which can be held in place within the cement head without being damaged or washed away by slurry flow, but which can be beneficially launched into said slurry flow at desired point(s) during the cementing process. The internal components of the cement head can be easily accessed using interrupted thread connections that can be quickly and easy connected and disconnected in the field without requiring specialized equipment. The cement head can be rigged up and remotely operated without requiring the lifting of personnel off the rig floor to actuate the tool or observe tool status.
Owner:FRANKS INT

Antibody-secreting cell assay

An improved assay is described where a surface is provided with immobilized anti-Ig antibodies rather than antigen and where specific antibody-secreting cells (ASC) are detected using soluble antigen probes containing one of several possible labels. The method gives improved sensitivity with less background and is also more representative because antigen binding does not employ immobilized antigen. The assay is particularly effective for measuring antibody secreting cells against HIV, for determining whether an infection is acute as opposed to old or latent, for mapping epitopes and for measuring for ASCs against different antigens in the same reaction.
Owner:MABTECH

On-line bidding system & method

A system and method (10) for online bidding wherein a seller (16) creates sale terms including a start or maximum sale price (22) and an end or minimum sale price (24) and a length of time (20) for each particular item or service (30) they want to sell. The sale of each item or service (30) items begins at the start price (22) and drops steadily throughout the length of time of the auction (20) until the item or service reaches the end price (24). A purchaser or bidder (12) has full access to the sale terms provided by the seller (16) including the start price (22), the end price (24), and the time length of the sale (20). A bidder (12) can bid based on either price or time.
Owner:BOCKH MATTHEW

Electric sail with voltage multipliers in tethers

The effective area of an electric sail depends on the voltage applied to tethers. The use of higher voltages is made possible by moving voltage multipliers to tethers, perhaps 100 meters out from the body of the spacecraft.
Owner:POSTQ IPR OY

Thromboxane receptor antagonists

ActiveUS9388127B2Substantial riskBeneficial pharmaceutical propertyOrganic chemistryOrganic compound preparationDiseaseTP Receptors
The invention generally relates to compounds that function as TP antagonists for treating thrombosis and other cardiovascular, renal, or pulmonary diseases. In some embodiments, the invention provides a compound including a substituted nitro phenoxy phenyl, a sulfonylurea, and an alkyl group. In some embodiments, the invention provides a method of treating thrombosis by administering an antithrombotic compound that preferentially binds to a thromboxane receptor, has preferential binding for either TPalpha (TPα) or TPbeta (TPβ) receptor subtype.
Owner:ATXA THERAPEUTICS LTD

Sports Protection Accessory with Attachable Face Mask

A sports helmet is provided including a filtering element attached to the lower portion of the face orifice to allow some degree of airflow in, but act as a barrier for the wearer from aerosolized exposure from reaching the eyes mouth and nose. Installed under or over a protective face cage, the filtering element is removably attached for allow for replaced as it gets dirty and / or damaged. The instant abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
Owner:KAYE CHRISTOPHER J

Safety improvements for UV radiation in aquatic applications

The invention provides an object (10) that during use is at least partly submerged in water, the object (10) further comprising an anti-biofouling system (200) comprising an UV emitting element (210), wherein the UV emitting element (210) is configured to irradiate with UV radiation (221) during an irradiation stage one or more of (i) a part (111) of an external surface (11) of said object (10) and (ii) water adjacent to said part (111) of said external surface (11), wherein the light source (220) is at least controllable between a first UV radiation level and a second UV radiation level, wherein the first UV radiation level is larger than the second UV radiation level, wherein the object (10) is selected from the group consisting of a vessel (1) and an infrastructural object (15), wherein the object (10) further comprises a control system (300) configured to control said UV 221 radiation (221) as function of input information comprising information of one or more of (i) a location of the object (10), (ii) movement of the object (10), (iii) a distance (d) of the object (10) to a second object (20), and (iv) a position of the part (111) of the external surface (11) relative to the water.
Owner:KONINKLJIJKE PHILIPS NV

Prosthesis having a large femoral head

ActiveUS20160278928A1Highly resistant to dislocationSubstantial riskJoint implantsFemoral headsBearing surfaceFemoral neck
A prosthesis comprises a femoral stem having a frustoconical femoral neck; a femoral head having an articular bearing surface with an outer diameter of 26 mm or more, and a frustoconically tapered internal recess; and a sleeve comprising a frustoconical body for insertion into the recess of the femoral head and a frustoconically tapered internal recess for receipt of the frustoconical femoral neck. A surface of the recess of the sleeve comprises oxidised zirconium or oxidised zirconium alloy to resist or minimise mechanically assisted crevice corrosion.
Owner:MCMINN DEREK JAMES WALLACE

Dry powder compositions and systems for poultry vaccination

InactiveUS20090041852A1Easy and efficient distributionSolve bulkyAntibacterial agentsSsRNA viruses negative-senseVaccinationInhalation
This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or non-reducing sugar and a biocompatible polymer, said dry powder composition being in the form of particles having an average particle size from 2 to 30 μm and a particle size polydispersity from 1.1 to 4.0. This invention also relates to a method for producing said dry powder compositions and a system for vaccination of poultry by inhalation.
Owner:UNIV GENT

Concrete having excellent explosion resistance

This invention provides a concrete having excellent exploding resistance, comprising a fiber as one constituent material, wherein said concrete has a compressive strength of 50 N / mm2 or more, a bending strength of 6 N / mm2 or more, and a ratio of the bending strength to the compressive strength is 15 or less. Upon explosion of an explosive material near a structure, a part of the structure is separated by explosion energy. In general, the separation of the structure on the side opposite to the side facing explosion is larger than that of the side facing explosion, it could trigger collapse of concrete, and the separation on this side has a larger risk of injuring persons within the structure. Since the present invention has the effect of reducing a separated volume, it can be used for various structures as a concrete for lifesaving or for preventing the collapse of the structure.
Owner:TOYOBO CO LTD

Safety device in electric power tools and/or electrical appliances

In a sensor device in electric power tools and / or electrical appliances which have a mains-operated electric drive motor in a housing, a sensor device is provided, which monitors a properly closed state of the housing and upon a deviation from the properly closed state switches the drive motor to be voltage-free.
Owner:ROBERT BOSCH GMBH

Method of charging a lithium-sulphur cell

A method for charging a lithium-sulphur cell, said method comprising: monitoring the voltage, V, of a cell during charge as a function of time, t, or capacity, Q, determining, in a voltage region in which the cell transitions between the first stage and second stage of charge, the reference capacity, Qref, of the cell at which dV / dt or dV / dQ is at a maximum, terminating charge when the capacity of the cell reaches a.Qref, where a is 1.1 to 1.4.
Owner:GELION TECH PTY LTD
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