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6results about How to "Increase savings" patented technology

Hyaluronic acid modified metal coordination albumin nanoparticles as well as preparation method and application thereof

The invention relates to the technical field of biological medicines, and discloses hyaluronic acid modified metal coordination albumin nanoparticles as well as a preparation method and application thereof. The hyaluronic acid modified metal coordination albumin nanoparticle comprises a core and a hyaluronic acid shell layer, wherein the core is formed by self-assembly of an albumin-drug compound, poly-L-aspartic acid and ferric ions through coordination, and the hyaluronic acid shell layer is connected to the surface of the core through coordination or adsorption. According to the hyaluronic acid modified metal coordination albumin nanoparticles as well as the preparation method and the application thereof, the preparation method is simple, convenient and rapid, does not need complex covalent modification, is mild in condition and is easy for large-scale production, and the prepared nanoparticles are uniform in particle size, good in stability and high in stability. In addition, due to the fact that the hyaluronic acid is modified on the surface, the active targeting capacity on CD44 receptor high-expression tumor cells is achieved, the enrichment and treatment effects of the medicine on the tumor site are remarkably improved, and the application prospect in preparation of the anti-tumor medicine is wide.
Owner:ZHEJIANG CANCER HOSPITAL

A shampoo hair conditioner ingredient delivery device

This utility model provides a shampoo and hair care ingredient release device, belonging to the technical field of release devices. It includes a storage bottle body and a storage bottle cap. A pump-feeding bottle body is mounted on the storage bottle body, and a piston is installed inside the pump-feeding bottle body. A one-way valve is located at the bottom of the pump-feeding bottle body. A pump head is located above the storage bottle cap, and a pump body is located inside the storage bottle cap. An adjustment knob is located on the top of the pump head, and a flow-limiting head is located below the adjustment knob. A stirring component for stirring is located at the bottom of the storage bottle body. The user can drive the piston inside the pump-feeding bottle body to move, replenishing the hair care ingredients in the pump-feeding bottle body into the shampoo in the storage bottle body through the pump nozzle and the one-way valve. This improves the flexibility of adding hair care ingredients, and the pump head can buffer the pumped shampoo to prevent it from being pumped too far, thus improving the dispensing stability of the device.
Owner:CHUNAN QIANDAO LAKE CAPITAL LUXURIANT COMMODITY CO LTD

A lactadherin-derived calcium-chelating peptide and use thereof

This invention discloses a lactobridged protein-derived calcium chelating peptide and its applications, belonging to the field of bioactive small molecule peptide technology. The calcium chelating peptide provided by this invention is safe and non-toxic, exhibiting better physicochemical activity compared to traditional calcium supplements. Its calcium chelating capacity reaches over 419.36 μg / mg, and it can promote calcium transport in the Caco-2 cell monolayer, thereby improving calcium absorption and bioavailability in the human body, making it suitable for use as a calcium supplement. This invention can develop a new protein source for calcium supplements and makes a significant contribution to the high-value utilization of dairy products.
Owner:JIANGNAN UNIV

Electric vehicle collaborative power grid power supply recovery strategy considering multi-time-domain EV-EPSV

PendingCN121961271ARealize dynamic quantitative assessmentOvercome the inability to reflect vehicle spatio-temporal travel characteristicsMathematical modelsForecastingPower gridElectric vehicle
An electric vehicle collaborative power grid power supply recovery strategy considering multi-time-domain EV-EPSV comprises the steps that a multi-time-sequence electric vehicle EV equivalent power supply model is established according to a travel rule of an electric vehicle user in a typical travel scene; a load importance index system is constructed, a load power loss model is established in combination with the load capacity and the power failure duration, and quantitative calculation of economic and social losses of different types of loads in the multi-time-sequence power failure process is achieved; and constructing a collaborative optimized power supply model of the electric vehicle EV and the emergency power supply vehicle EPSV, and realizing static power distribution of the electric vehicle and dynamic path and power optimization scheduling of the emergency power supply vehicle. According to the strategy, a multi-time-sequence EV equivalent power supply model is established, a load power loss evaluation system is constructed, and a collaborative optimization scheduling method of the electric vehicle and the emergency power supply vehicle is provided, so that efficient distribution of limited power supply resources and improvement of power supply recovery efficiency are realized. The scheduling flexibility of electric vehicle resources and the power supply toughness of a power grid can be effectively improved in a sudden power failure situation.
Owner:CHINA THREE GORGES UNIV

Modeling method of multi-time-sequence EV equivalent power supply model considering vehicle travel rule

PendingCN121960110AOvercome the inability to reflect vehicle spatio-temporal travel characteristicsRealize dynamic quantitative evaluationBiological modelsDesign optimisation/simulationResidential sectorMarkov chain
A multi-time-sequence EV equivalent power supply model modeling method considering a vehicle travel rule comprises the following steps: according to dynamic evolution characteristics of the travel rule of an electric vehicle user, combining travel sample data, dividing into a summer scene and a winter scene according to seasons, and dividing into a workday scene and a holiday scene according to a time sequence to complete data fitting; then, a vehicle travel state transition matrix is established through a semi-Markov chain SMC, and a Monte Carlo method MCM is utilized to perform random simulation on vehicle behaviors to obtain available discharge capacities of the electric vehicles at all moments, so that an electric vehicle cluster in a region is equivalent to a time-varying power supply model, and a multi-time-sequence EV equivalent power supply model is established; according to the method, by introducing a semi-Markov chain and a Monte Carlo random simulation method, available energy storage capacity distribution characteristics of an electric vehicle group in different scenes are described. The model can reflect energy storage laws of residential areas, working areas and shopping areas in different seasons and days, and dynamic quantitative evaluation of the EV available power potential is realized.
Owner:CHINA THREE GORGES UNIV

Barrel type foundation structure anticorrosive coating thickness control method and device considering multi-factor coupling effect and medium

ActiveCN121979300AFully consider complex coupling effectsImprove film thickness prediction accuracySpraying apparatusMachine learningData setLayer thickness
The invention relates to a barrel type foundation structure anticorrosive coating thickness control method and device considering a multi-factor coupling effect and a medium. The method comprises the steps that S1, a coating dry film thickness prediction model is constructed based on a simulation data set and a historical data set; s2, acquiring a real-time environment wind speed and a spraying distance, and querying based on a pre-configured response surface database to obtain a reference spraying pressure and a reference nozzle walking speed; s3, on the basis of the coating dry film thickness prediction model, a spraying pressure correction sequence and a nozzle walking speed correction sequence are obtained by minimizing film thickness control deviation and fluctuation targets of spraying pressure and nozzle walking speed in a period of time in the future; and S4, respectively superposing to the corresponding reference spraying pressure and the reference nozzle walking speed to obtain the target spraying pressure and the target nozzle walking speed. Compared with the prior art, the method has the advantages that the film thickness prediction precision under variable working conditions is improved, and accurate closed-loop control of the coating thickness is realized.
Owner:SOUTHEAST UNIV +1