19results about How to "Increase savings" patented technology

The invention discloses a ternary carrier-free nanoparticle as well as a preparation method and application thereof. The ternary carrier-free nanoparticles comprise nanoparticles which are formed by the chlorine e6, the lonidamine and the RG108 through an intermolecular interaction force. The nanoparticles can improve effective absorption and accumulation of drugs in tumors, can induce tumor specific pyroptosis and immunogenic effect under laser irradiation, and can promote maturation of antigen presenting cells and recruitment and activation of cytotoxic T lymphocytes, thereby starting adaptive anti-tumor immunity.

The invention relates to the technical field of biological medicines, and discloses hyaluronic acid modified metal coordination albumin nanoparticles as well as a preparation method and application thereof. The hyaluronic acid modified metal coordination albumin nanoparticle comprises a core and a hyaluronic acid shell layer, wherein the core is formed by self-assembly of an albumin-drug compound, poly-L-aspartic acid and ferric ions through coordination, and the hyaluronic acid shell layer is connected to the surface of the core through coordination or adsorption. According to the hyaluronic acid modified metal coordination albumin nanoparticles as well as the preparation method and the application thereof, the preparation method is simple, convenient and rapid, does not need complex covalent modification, is mild in condition and is easy for large-scale production, and the prepared nanoparticles are uniform in particle size, good in stability and high in stability. In addition, due to the fact that the hyaluronic acid is modified on the surface, the active targeting capacity on CD44 receptor high-expression tumor cells is achieved, the enrichment and treatment effects of the medicine on the tumor site are remarkably improved, and the application prospect in preparation of the anti-tumor medicine is wide.

The invention relates to the technical field of assembling devices, and discloses an automatic trichogramma ball buckling and assembling device which comprises an equipment box, a first feeding machine and a second feeding machine, the first feeding machine and the second feeding machine are used for feeding two semicircles of a trichogramma ball respectively, the automatic trichogramma ball buckling and assembling device further comprises an equipment table, the equipment table is fixedly installed on the top of the equipment box, and the first feeding machine and the second feeding machine are used for feeding the two semicircles of the trichogramma ball respectively. A base is fixedly mounted in the middle of the top of the equipment table. By arranging the buckling auxiliary mechanism, when a buckled bee ball passes through the lower portion of the material blocking support, the unbuckled bee ball can be extruded and buckled by means of an inclined face on one side of an extrusion block, products which are seriously staggered in buckling and pressing and cannot be corrected through the extrusion block can be extruded and separated by the extrusion block, and then the product is prevented from being damaged. And then the products are separated from the finished product area through the discharging mechanism, so that the phenomenon that the products which are not tightly buckled are scattered and leaked when being transferred is effectively avoided, and the effectiveness of buckling and assembling of the equipment is improved.

The utility model provides a video image intelligent identification terminal. The video image intelligent identification terminal comprises a first column body and a second column body, a solar panel is fixedly installed on the side face of the second column body, one side of the first column body is fixedly sleeved with a first supporting plate, and the other side of the first column body is fixedly sleeved with a second supporting plate. The top of the first supporting plate is fixedly connected with a first box body. The video image intelligent identification terminal provided by the utility model is provided with the solar panel, when video monitoring processing is carried out, the solar panel is started, so that the solar panel converts solar energy into electric energy and transmits the electric energy into the storage battery for storage, and at the moment, the storage battery continuously supplies power to the processing host; therefore, the effect that the processing host keeps the continuous standby work is achieved, the problem that much electric energy needs to be consumed during long-time video monitoring processing is avoided, and the effect of saving the electric energy during video monitoring processing is improved.

The utility model provides a continuous stirring pulp blending device for sweet potato starch. The continuous stirring pulp blending device for sweet potato starch comprises a box body, the top of the box body is fixedly connected with a first supporting column, the top of the first supporting column is fixedly connected with a second supporting column, and the top of the first supporting column is fixedly connected with a stirring box. According to the continuous stirring pulp blending device for the sweet potato starch, provided by the utility model, the delivery pump is arranged, and when starch is stirred and blended, the delivery pump is started, so that the delivery pump can absorb water flow in the box body through the floating block and the absorption pipe, and then the water flow is discharged into the stirring box through the water delivery pipe; the water flow can wash sweet potato residues in the stirring box, so that the continuous recycling effect of the water flow is achieved, the problem that a large amount of water flow needs to be consumed when sweet potato starch is blended is avoided, and the water flow saving effect is improved.

The utility model provides an atomizing hair straightening comb. The atomizing hair straightening comb comprises a hair straightening comb body, a control circuit board arranged in the hair straightening comb body, a smoke cartridge assembly used for atomizing essential oil, an air pump unit used for pumping mist and smoke and comb teeth located at one end of the hair straightening comb body. The smoke cartridge assembly comprises a ceramic heating core used for heating and atomizing essential oil and further comprises a smoke storage bin fixedly arranged on the inner side of the comb teeth and a heat insulation piece located between the smoke storage bin and the comb teeth. The air pump unit is communicated with the smoke cartridge assembly through an air inlet hose and communicated with the smoke storage bin through the mist outlet hose, and mist and smoke are pumped into the smoke storage bin from the smoke cartridge assembly. The PTC heating piece and the NTC temperature control sensor are arranged on the inner side of the comb tooth part, and in practical application, the smoke storage bin and the heat insulation piece can be well utilized, so that the fog accumulation and fog outlet effects are improved.

This utility model provides a shampoo and hair care ingredient release device, belonging to the technical field of release devices. It includes a storage bottle body and a storage bottle cap. A pump-feeding bottle body is mounted on the storage bottle body, and a piston is installed inside the pump-feeding bottle body. A one-way valve is located at the bottom of the pump-feeding bottle body. A pump head is located above the storage bottle cap, and a pump body is located inside the storage bottle cap. An adjustment knob is located on the top of the pump head, and a flow-limiting head is located below the adjustment knob. A stirring component for stirring is located at the bottom of the storage bottle body. The user can drive the piston inside the pump-feeding bottle body to move, replenishing the hair care ingredients in the pump-feeding bottle body into the shampoo in the storage bottle body through the pump nozzle and the one-way valve. This improves the flexibility of adding hair care ingredients, and the pump head can buffer the pumped shampoo to prevent it from being pumped too far, thus improving the dispensing stability of the device.

This invention discloses a lactobridged protein-derived calcium chelating peptide and its applications, belonging to the field of bioactive small molecule peptide technology. The calcium chelating peptide provided by this invention is safe and non-toxic, exhibiting better physicochemical activity compared to traditional calcium supplements. Its calcium chelating capacity reaches over 419.36 μg / mg, and it can promote calcium transport in the Caco-2 cell monolayer, thereby improving calcium absorption and bioavailability in the human body, making it suitable for use as a calcium supplement. This invention can develop a new protein source for calcium supplements and makes a significant contribution to the high-value utilization of dairy products.

The utility model provides a multistage mixing device for alkyd paint. The alkyd paint multi-stage mixing device comprises a supporting table, the top of the supporting table is fixedly connected with a first box body, an air cylinder is fixedly installed at the top of the first box body, and the bottom of the air cylinder is fixedly connected with a first pushing frame. According to the alkyd paint multi-stage mixing device provided by the utility model, by arranging the air cylinders, when paint is mixed and needs to be discharged, the air cylinders are started, so that the two air cylinders can drive the first pushing frame and the second pushing frame to move up and down; at the moment, the first pushing frame and the second pushing frame which move up and down can scrape the inner wall of the first box body, so that paint adhered to the inner wall of the first box body can be pushed to the bottom of an inner cavity of the first box body by the first pushing frame and the second pushing frame, and the paint discharging effect is improved; and the problem that the paint is adhered to the inner wall of the first box body and is difficult to discharge, so that the paint is wasted is solved, and the saving effect during paint mixing is improved.

The utility model discloses a dyeing vat with dye function is saved, including vertical dip dye vat jar body, the lower side fixed mounting of vertical dip dye vat jar body front end surface has the liquid pump valve, one side of liquid pump valve upper end surface is connected with the return pipe, and the inside upper side of return pipe is equipped with the liquid outlet. Through the utility model uses vertical dip dye vat jar body to be able to circulate up and down flow dye when dip dyeing coloring, and the dye in the process of flowing, through stepping motor, transmission shaft, grinding disc, grinding ring and fine grinding groove can carry out grinding operation to it simultaneously, through above technical scheme, guarantee the dye fluidity, prevent dye from happening settlement phenomenon simultaneously, can regrind the flocculation precipitate generated by calcium ion in water source and dye or auxiliary agent, this structure can improve the utilization of dye, to reduce the endless loss of dye, improve vertical dip dye vat jar body whole dye saving rate.

The invention discloses a hybrid cell membrane disguised hexagonal boron nitride nano-particle as well as a preparation method and application thereof, relates to the technical field of medicines, and aims to solve the problems of poor targeting property and biocompatibility of a boron carrying agent, insufficient in-vivo stability and tumor accumulation capacity of nano-particles and the like in BNCT tumor treatment in the prior art. The composite material comprises hexagonal boron nitride nanoparticles and a hybrid cell membrane coating the peripheries of the hexagonal boron nitride nanoparticles, and the hybrid cell membrane is formed by fusing a macrophage cell membrane and a tumor cell membrane. The targeting property and biocompatibility of the boron carrying agent and the in-vivo stability and tumor accumulation capacity of nanoparticles can be effectively enhanced, and the BNCT treatment effect of glioma is improved.

The invention discloses a preparation method of IR780 and gambogic acid prodrug-loaded lipidosome, which comprises the following steps: dissolving mPEG-TK-NH2 in dimethylformamide, adding gambogic acid, benzoyl peroxide and triethylamine, stirring for reaction, concentrating and recrystallizing to obtain mPEG-TK-GA, adding mPEG-TK-GA, soybean phosphatidylcholine, cholesterol and IR780 into an organic solvent, and carrying out rotary evaporation to remove the organic solvent, thereby obtaining the IR780 and gambogic acid prodrug-loaded lipidosome. The SIRP-alpha gene engineering exosome preparation method comprises the following steps: preparing a lipid membrane, adding a phosphate buffer solution, heating, carrying out ultrasonic treatment, granulating to obtain a liposome solution, mixing an SIRP-alpha gene engineering exosome and IG Lipo, and carrying out membrane fusion by adopting a freeze-thaw method to obtain the SIRP-alpha gene engineering exosome preparation. Compared with the prior art, the liposome prepared by the method has a responsive drug release effect, can relieve toxic and side effects while improving the treatment effect, is also loaded with IR780, and can reduce the dosage and improve the treatment effect in combination with photothermal therapy.

The utility model discloses a photovoltaic pest killing device for agricultural planting, which comprises a bottom plate, the top of the bottom plate is provided with a pest prevention assembly, and the top of the pest prevention assembly is provided with a solar assembly; the fixing frame is arranged at the top of the bottom plate, the weak current radiation net cover is arranged on one side of the fixing frame, the frame is arranged at the top of the bottom plate, the blocking plate is arranged in the frame, and the blocking plate is located on one side of the weak current radiation net cover. By arranging the solar assembly, a power source can be provided for the pest removal assembly through solar energy in the process, solar energy storage and electric power conversion can be achieved, the pest removal assembly can get rid of connection of a long power line in the using process, energy consumption is reduced, and the pest removal efficiency is improved. And a power supply can be provided for the pest removal assembly at night, so that the energy conservation is improved, and the energy efficiency of the pest removal assembly is ensured.

An electric vehicle collaborative power grid power supply recovery strategy considering multi-time-domain EV-EPSV comprises the steps that a multi-time-sequence electric vehicle EV equivalent power supply model is established according to a travel rule of an electric vehicle user in a typical travel scene; a load importance index system is constructed, a load power loss model is established in combination with the load capacity and the power failure duration, and quantitative calculation of economic and social losses of different types of loads in the multi-time-sequence power failure process is achieved; and constructing a collaborative optimized power supply model of the electric vehicle EV and the emergency power supply vehicle EPSV, and realizing static power distribution of the electric vehicle and dynamic path and power optimization scheduling of the emergency power supply vehicle. According to the strategy, a multi-time-sequence EV equivalent power supply model is established, a load power loss evaluation system is constructed, and a collaborative optimization scheduling method of the electric vehicle and the emergency power supply vehicle is provided, so that efficient distribution of limited power supply resources and improvement of power supply recovery efficiency are realized. The scheduling flexibility of electric vehicle resources and the power supply toughness of a power grid can be effectively improved in a sudden power failure situation.

A multi-time-sequence EV equivalent power supply model modeling method considering a vehicle travel rule comprises the following steps: according to dynamic evolution characteristics of the travel rule of an electric vehicle user, combining travel sample data, dividing into a summer scene and a winter scene according to seasons, and dividing into a workday scene and a holiday scene according to a time sequence to complete data fitting; then, a vehicle travel state transition matrix is established through a semi-Markov chain SMC, and a Monte Carlo method MCM is utilized to perform random simulation on vehicle behaviors to obtain available discharge capacities of the electric vehicles at all moments, so that an electric vehicle cluster in a region is equivalent to a time-varying power supply model, and a multi-time-sequence EV equivalent power supply model is established; according to the method, by introducing a semi-Markov chain and a Monte Carlo random simulation method, available energy storage capacity distribution characteristics of an electric vehicle group in different scenes are described. The model can reflect energy storage laws of residential areas, working areas and shopping areas in different seasons and days, and dynamic quantitative evaluation of the EV available power potential is realized.

The invention belongs to the technical field of biological medicines, and discloses application of brucea javanica bitter alcohol in preparation of anti-leukemia medicines. Test results show that the brucea javanica bitter alcohol can inhibit the cell activity of leukemia cells and cause apoptosis and cell cycle arrest of the leukemia cells. The brucea javanica picrol promotes leukemia cell lipid peroxidation and intracellular ferrous ion accumulation to cause ferroptosis by inhibiting protein expression of an antioxidant transcription factor Nrf2 and downstream NQO1 of the antioxidant transcription factor Nrf2, and the brucea javanica picrol and a ferroptosis inducer Erastatin exert the anti-leukemia synergistic effect. The application proves that the brucea javanica picrol has a good anti-leukemia effect on leukemia cells, prompts that a ferroptosis pathway is one of the effective anti-leukemia pathways, is used for preparing the medicine for treating leukemia, and provides a brand-new thought for developing a drug administration scheme for treating leukemia.

The invention relates to a barrel type foundation structure anticorrosive coating thickness control method and device considering a multi-factor coupling effect and a medium. The method comprises the steps that S1, a coating dry film thickness prediction model is constructed based on a simulation data set and a historical data set; s2, acquiring a real-time environment wind speed and a spraying distance, and querying based on a pre-configured response surface database to obtain a reference spraying pressure and a reference nozzle walking speed; s3, on the basis of the coating dry film thickness prediction model, a spraying pressure correction sequence and a nozzle walking speed correction sequence are obtained by minimizing film thickness control deviation and fluctuation targets of spraying pressure and nozzle walking speed in a period of time in the future; and S4, respectively superposing to the corresponding reference spraying pressure and the reference nozzle walking speed to obtain the target spraying pressure and the target nozzle walking speed. Compared with the prior art, the method has the advantages that the film thickness prediction precision under variable working conditions is improved, and accurate closed-loop control of the coating thickness is realized.

The invention relates to the field of fair-lead devices, in particular to a ship fair-lead device and a fair-lead method of the ship fair-lead device. Comprising an auxiliary assembly, a fairlead assembly is installed on the top of the auxiliary assembly, a cleaning assembly is installed on the top of the fairlead assembly, the fairlead assembly comprises two sets of third discs, and a fairlead pipe is connected between the two sets of third discs; a second compression spring is extruded while a sleeving ring slides on the cable guide pipe, a pressure sensor is extruded, the pressure sensor gives an alarm when being impacted, a first extrusion head structure and a cable are extruded due to sliding of the sleeving ring at the moment, a lubricating solution is sprayed out in the extrusion process to protect the cable, and the service life of the cable is prolonged. The solution saving effect is improved through autonomous extrusion, the cable deviation angle is judged through the numerical value of the pressure sensor, the cable protection range is widened, and meanwhile the working effect of the fair lead is improved.

The invention discloses a new energy system data classification updating method and device and a storage medium, and relates to the technical field of new energy data classification updating, and the method comprises the following steps: obtaining new energy system data, and carrying out the two-dimensional classification of the new energy system data; setting exception classification, and dynamically updating a judgment rule of the exception classification based on historical data of the new energy system data; further classifying and updating the new energy system data based on the judgment rule; the method is used for solving the problem that in an existing new energy data classification updating technology, an updating method is too basic, abnormal data are not recognized, and consequently a user cannot find that new energy data are abnormal at the first time.