32 results about "Adverse drug event" patented technology

The smart medical compliance method and system invention prevents adverse drug events through the use of protocols that uniquely identifies the patient, care provider, medication and/or medical device that is to be used with radio frequency identification (RFID). The RFID devices incorporate fail-safe locks or indicators that prevent the inadvertent or unauthorized use of medication, medical devices, or medical supplies. The system corroborates, patient, the care provider, the medical device, and the manner in which it is to be used, and authorizes the action to be undertaken through an interface on a personal digital assistant PDA over a wireless communication channel. The system also timestamps events in the equivalent of a medical black box such that records may be kept to further improve patient care and allow an analysis of procedures. In addition, the system includes interfaces to medication preparation and safe disposal. A number of smart devices that interact with the system are also described. These include smart medical containers, smart clamps, smart valves, smart syringes, smart couplers, smart pipettes, and a host of other point of care devices.

An algorithm according to an embodiment of the present invention provides for latent signal detection of adverse events. Embodiments infer the presence of adverse drug events from large observational databases housed by the FDA, WHO, and other governmental organizations. The disclosed algorithms do not require the adverse event to be reported explicitly. Instead, the algorithms infer the presence of adverse events through more common secondary effects. In an embodiment, machine learning techniques are used for this purpose.

A method of parenterally administering a composition, the method including parenterally administering to a person a composition including at least one omega-3 fatty acid and at least one drug, wherein the at least one omega-3 fatty acid source and the at least one drug are administered simultaneously.

A dual smart card system and method including a central exchange server which collects patient healthcare data from a plurality of healthcare providers and stores the data in its central data bases. Each healthcare provider and each patient has a smart card and both smart cards must be used when a provider prescribes a medication for the patient and when the pharmacy fills the prescription for the patient. The patients' medical information is stored on the patient's smart card and on the central database. The system makes the stored medical information immediately available to participating organizations and tracks the entire life cycle of the prescription and generates alerts for adverse drug events, fraud, and duplication.

A method for detecting an adverse drug event in a patient. The method includes reading an adverse drug reaction (ADR) description of the patient, reading identifiers for medications currently taken by the patient, and accessing ADR records corresponding to the identifiers. Each record comprises an identifier for a medication, an ADR description for the medication and a risk profile for the medication. Next, the method compares the ADR description of the patient with ADR descriptions in the ADR records, identifies an ADR record with a matching ADR description and calculates a level of risk that a medication of the ADR record is causing the ADR description of the patient. Finally, the method transmits an identifier and a risk profile for each medication of the ADR record, and a notice indicating that each medication of the ADR record may be causing the ADR description of the patient.

A method of extracting a combination of a drug and an adverse event related to the drug includes: for each of positive example combinations, negative example combinations and combinations that are neither positive examples nor negative examples, which are combinations of drug and disease, extracting medical events from medical information data about a patient and generating attribute data based on time-series information about the medical events; and learning a discriminant model based on attribute data of the positive and negative examples; and inputting attribute data corresponding to the combinations that are neither positive examples nor negative examples to the discriminant model to determine scores.

The invention discloses a method for reading prescription drug properties by using a computer. The method comprises a knowledge database, information input by a user and reasonable drug use review analysis; after the information input by the user and the reasonable drug use review analysis, an analysis result is fed back to a user information input interface; the reasonable drug use review analysis is comparative analysis with the knowledge database; and the knowledge database comprises patient information, drug information and a drug knowledge library. According to the method, automatic review of prescriptions and medical advices is realized; potential unreasonable drug use problems are discovered in time; clinical professionals such as doctors, pharmacists and the like are assisted to master and use medical knowledge effectively in time in a drug use process; the occurrence of adverse drug events is prevented; the technical progress of clinical reasonable drug use work is promoted; and the occurrence of medical events is reduced.

The invention relates to an application of a traditional Chinese medicine composition in preparation of a medicine for treating novel coronavirus pneumonia, in particular to an application in preparation of a medicine for treating a lung-spleen qi deficiency syndrome in a clinical treatment recovery phase of the novel coronavirus pneumonia. The traditional Chinese medicine composition is prepared by compatibility of thirteen traditional Chinese medicinal materials including prepared rehmannia root, radix aconiti lateralis praeparata (black prepared aconite root), moutan bark, radix achyranthis bidentatae, salted fructus psoraleae, fructus amomi, semen plantaginis, poria cocos, salted fructus alpiniae oxyphyllae, cinnamon, Chinese yam, rhizoma alismatis, fructus rosae laevigatae and the like according to the principle of monarch, minister, assistant and guide. The medicines are used for warming kidney, absorbing qi, tonifying spleen and reducing phlegm together. Clinical test results show that the traditional Chinese medicine composition can significantly improve the traditional Chinese medicine syndrome integral of a patient in the convalescent stage of the new crown pneumonia, and has significant symptom remission rate and relatively fast symptom remission time for new crown pneumonia symptoms such as weakness, cough and the like. In addition, the composition is free of adverse drug events and good in safety.

The invention relates to the technical field of medical data processing systems, in particular to an anticoagulant drug treatment management follow-up visit system which comprises a patient basic information data acquisition module, a medication evaluation module, a problem and evaluation module, a medication planning module, a physician end, a pharmacist end and a patient end. By adopting the system provided by the invention, the working efficiency of medical staff is improved, analysis and suggestion are carried out according to the medication condition of the patient, the safety of the patient when the patient uses the anticoagulant drug is enhanced, the medication condition of the patient is standardized, meanwhile, the medical staff can conveniently know the medication condition of the patient in time, and adverse drug events are reduced.

The invention provides application of a traditional Chinese medicine composition in preparation of an anti-novel coronavirus drug. The traditional Chinese medicine composition is a Kegan sore-throat relieving composition, and in-vitro experimental results show that the anti-novel coronavirus effect means that the composition can inhibit Vero E6 cells infected with novel coronavirus from causing cytopathy and inhibit mRNA over-expression of inflammatory factors TNF-a, IL6, IL-8 and MCP-1 induced by SARS-CoV-2. Clinical test results show that the Kegan sore-throat relieving composition has a higher symptom relieving rate and shorter symptom relieving time for novel coronary pneumonia symptoms such as fever, cough and pharyngalgia and the like, and can stabilize the condition of a patient ina novel coronary pneumonia recovery period; and no adverse drug event occurs, and the safety is good.

The invention provides an active monitoring and evaluation warning system for adverse drug events in hospitalized patients. Before the system is set up, a plurality of linked servers and a reporting system are set up. The reporting system transmits the patient's medication information and doctor's orders to the plurality of linked servers; a think tank is formed according to the set rules; after the completion of the think tank construction, the system includes a task setting module, an HIS module, an inclusion module, an exclusion module, a judgment module, a think tank examination module, amanual evaluation module, a feature analysis module, and a risk warning module; and the task setting module, the HIS module, the inclusion module, the exclusion module, the judgment module, the thinktank examination module, the manual evaluation module, the feature analysis module, and the risk warning module are sequentially connected.

Methods for improving the therapeutic effectiveness of uridine administered to prevent and/or reduce various maladies including adverse event from drugs are provided. Aspects of the methods include administering an effective amount of a uridine maximizing adjuvant, e.g., a 2,2′-anhydropyrimidine, or a derivative thereof, to the subject. Also provided are compositions for use in practicing the subject methods. The subject methods and compositions find use in a variety of different applications, including the treatment of a variety of different disease conditions.

The invention discloses an equivalent signal mining method oriented to SRS combined drug adverse reaction signals, including acquiring data through the spontaneous reporting system SRS of drug adverse events, and obtaining the combined drug adverse reaction signal set X={D ₁ ,D ₂ ,...,D _x},D _x To determine the drug combination as an adverse reaction signal; give priority to the signal with the smallest size of the drug combination set, and solve the largest equivalence group D of D ^G , combined with D ^G The largest equivalence group with intersection to the largest equivalence group D ^G ; then will not belong to D ^G And the signal equivalent to D is merged into D ^G , the D ^G Join X ^G , output the largest set of equivalence groups X ^G . x ^G Each maximum equivalence group in is the signal set with pairwise equivalence relationship between the adverse reaction signals of combined drug use. Select a signal from the maximum equivalence group to represent the signal set (that is, the maximum equivalence group), and participate in other data Analysis is beneficial to reduce the workload of the overall analysis.

The invention relates to an atypical antipsychotic medicinal composition. The medicinal composition contains active components risperidone and sertraline hydrochloride according to a weight ratio of 0.04:1 to 0.08:1, and is applied to the treatment of SCZ when the dosage of risperidone in the active components is 2-4 mg/d. Low-dosage risperidone and sertraline hydrochloride in the medicinal composition have excellent synergistic effects; and compared with medium and high dosage risperidone, the medicinal composition has the advantages of equivalent positive symptom elimination effect, significant elimination of negative symptoms and emotion symptoms, and improvement of the social function of SCZ patients when used in the treatment of SCZ. The medicinal composition greatly reduces the occurrence probability of medium and high dosage risperidone induced hyperprolactinemia, severe extrapyramidal symptoms and other adverse drug events.