Soothing and moisturizing compound as well as preparation method and application thereof

Abstract

The invention relates to the technical field of raw materials of skin care products, and particularly discloses a soothing and moisturizing compound as well as a preparation method and application thereof. The preparation method of the soothing and skin-moistening compound comprises the following steps: 1) mixing rice, cornflower, quisqualis indica, cashew nut and water, heating and extracting to obtain a pre-extract; (2) adding compound bacteria into the pre-extract, and fermenting to obtain a fermented product; the invention discloses a soothing and skin-moistening compound and a preparation method thereof.The soothing and skin-moistening compound has the advantages that the soothing and skin-moistening compound is prepared from compound bacteria of streptomyces cinereorubens fructose fermentation subspecies, fermented lactobacillus mucus and pediococcus pentosaceus, and the soothing and skin-moistening compound is more remarkable in soothing effect.

Description

Technical Field

[0001] The invention relates to the field of skin care product raw materials, and in particular to a soothing and moisturizing complex, a preparation method thereof and an application thereof. Background Art

[0002] At present, the market demand for skin care products with natural ingredients is growing, and consumers are increasingly preferring effective skin care ingredients from nature. Natural plant extracts have certain care effects on the skin. Adding them to skin care products can improve the skin care effect. At the same time, because they replace chemical synthetic raw materials, skin care products are less irritating to the skin, and are one of the main choices for consumers today.

[0003] As people use cosmetics more and more frequently, the ingredients in cosmetics are more irritating to the skin, causing the skin to be easily damaged and gradually turn into sensitive skin. Therefore, skin care products with soothing effects are the demand of most consumers. By adding plant extracts with soothing effects to skin care products, it can not only reduce the irritation of the skin care products themselves, but also give the skin care products a certain soothing effect. However, although the products on the market can have a soothing effect, the effect is relatively general. It usually takes long-term use to show the effect. It is difficult to meet the needs of consumers for quick skin repair. Therefore, there is still room for improvement. Summary of the invention

[0004] In order to make the soothing effect more significant, the present application provides a soothing emollient complex, a preparation method thereof, and an application thereof.

[0005] In a first aspect, the present application provides a method for preparing a soothing and moisturizing complex, using the following technical solution: A method for preparing a soothing emollient complex comprises the following steps: Step 1), mixing rice, cornflower, Quisqualis cretica, cashew nut and water, and heating for extraction to obtain a pre-extract; Step 2), adding composite bacteria to the pre-extract, fermenting, and obtaining a fermentation product; Step 3), filtering and sterilizing the fermented product to obtain an extract; Step 4), concentrating and drying the extract to obtain a soothing and moisturizing complex; The composite bacteria is a combination of fructose fermentation subspecies of Streptomyces erythrorhizogenes, fermentation Lactobacillus mucus, and Pediococcus pentosaceus.

[0006] By adopting the above technical scheme, by selecting a combination of rice, cornflower, Quisqualis creeper and cashew nut, and by fermenting with fructose fermentation subspecies of Streptomyces erythrorhizon, fermentation Lactobacillus mucilaginosus and Pediococcus pentosaceus, the active ingredients and the fermentation products can cooperate with each other to significantly soothe the skin, quickly repair the skin, make the skin no longer prone to allergies, quickly eliminate skin discomfort, and well meet the needs of consumers. In addition, after the active ingredients and the fermentation products are combined, they can also promote the skin to restore elasticity and make the skin smoother. The skin care effect is very significant and is deeply loved by consumers.

[0007] Preferably, the mass ratio of the rice, cornflower, Quisqualis creeper and cashew is 10-12:5-7:2-4:7-9.

[0008] By adopting the above technical solution and specifically selecting the mass ratio of rice, cornflower, Quisqualis creeper and cashew, the various active ingredients can cooperate with each other better, repair the skin better and relieve skin discomfort more quickly.

[0009] Preferably, the mass ratio of the rice, cornflower, Quisqualis creeper, cashew nut and water is 10-12:5-7:2-4:7-9:100-150.

[0010] By adopting the above technical scheme and specifically selecting the mass ratio of rice, cornflower, Quisqualis creeper, cashew nut and water, the extraction effect is better, the energy consumption required for later drying is reduced, the cost is better controlled, and the economic value is higher.

[0011] Preferably, the mass ratio of the fructose fermentation subspecies of Streptomyces erythrorhizogenes, the fermentation Lactobacillus mucilaginosus, and the Pediococcus pentosaceus is 2-3:4-5:3-4.

[0012] By adopting the above technical scheme and specifically selecting the mass ratio of the fructose fermentation subspecies of Streptomyces erythrorhizus, fermentation Lactobacillus mucus, and Pediococcus pentosaceus, the activity of each bacteria is higher, the fermentation effect is better, the effect of the fermentation product and the active ingredient being combined is better, and the effect of soothing the skin is better.

[0013] Preferably, the mass ratio of the rice, cornflower, Quisqualis creeper, cashew nut, Streptomyces erythrorhizon fructose fermentation subspecies, Lactobacillus mucilaginosus fermentation, and Pediococcus pentosaceus is 10-12: 5-7: 2-4: 7-9: 0.002-0.003: 0.004-0.005: 0.003-0.004.

[0014] By adopting the above technical scheme, by specifically selecting the mass ratios of rice, cornflower, Quisqualis creeper, cashew nut, Streptomyces erythrorhizon fructose fermentation subspecies, fermentation Lactobacillus mucilaginosus, and Pediococcus pentosaceus, the fermentation effect is better, and the effect of the cooperation between various active ingredients and fermentation products is further enhanced, the soothing effect is better, the skin can be repaired faster, and the skin is healthier.

[0015] Preferably, in step 1), the mixture is heated to boiling, condensed and refluxed, and extracted for 2-3 hours.

[0016] By adopting the above technical scheme, the active ingredients in rice, cornflower, Quisqualis creeper and cashew nut can be initially extracted, which helps to shorten the fermentation time, improve production efficiency and have higher economic value.

[0017] Preferably, in step 2), the temperature is kept at 33-35° C. and the fermentation is carried out for 7-9 days.

[0018] By adopting the above technical solution and maintaining the temperature at 33-35°C, the activity of each bacteria is higher, the fermentation effect is better, the fermentation time is shortened, and the quality of the prepared composite is better.

[0019] In a second aspect, the present application provides a soothing and moisturizing complex, which adopts the following technical solution: A soothing and moisturizing complex is prepared by the preparation method of the soothing and moisturizing complex.

[0020] By adopting the above technical solution, the soothing moisturizing complex has a significant soothing effect, and is derived from natural plants, has low irritation, can quickly repair the skin, makes the skin less prone to allergies, and can restore the elasticity of the skin, making the skin smoother.

[0021] In a third aspect, the present application provides an application of a method for preparing a soothing emollient complex, using the following technical solution: An application of the method for preparing the soothing and moisturizing complex as described above, wherein the soothing and moisturizing complex is added to skin care products for preparing skin care products with soothing and moisturizing effects, and the mass content of the soothing and moisturizing complex in the skin care products is 1-10%.

[0022] By adopting the above technical solution, the prepared skin care products can have a significant soothing effect while having conventional skin care effects, so that the skin repair effect is better and the effect is faster, and it can quickly relieve skin discomfort and well meet the needs of consumers.

[0023] In summary, this application has the following beneficial effects: 1. Since the present application uses a compound of rice, cornflower, Quisqualis creeper, and cashew nuts, and ferments them through Streptomyces erythrorhizon fructose fermentation subspecies, fermented Lactobacillus mucus, and Pediococcus pentosaceus, the active ingredients and the fermentation products cooperate with each other to significantly soothe the skin, quickly repair the skin, make the skin no longer prone to allergies, and quickly eliminate skin discomfort, which well meets the needs of consumers. In addition, after the active ingredients and the fermentation products are combined, they can also promote the skin to restore elasticity and make the skin smoother. The skin care effect is very significant and is deeply loved by consumers.

[0024] 2. In the present application, it is preferred to specifically select the mass ratio of rice, cornflower, Quisqualis creeper and cashew nut so that the various active ingredients can cooperate with each other better, repair the skin better and relieve skin discomfort faster.

[0025] 3. In the present application, it is preferred to specifically select the mass ratio of Streptomyces erythrorhizon fructose fermentation subspecies, Lactobacillus mucilaginosus fermentation, and Pediococcus pentosaceus so that the activity of each bacteria is higher, the fermentation effect is better, the effect of the fermentation product and the active ingredient is better, and the effect of soothing the skin is better. DETAILED DESCRIPTION

[0026] The present application is further described in detail below with reference to the embodiments.

[0027] Example 1 A soothing and moisturizing complex, the preparation method of the soothing and moisturizing complex is as follows: Step 1), 10kg of rice, 5kg of cornflower, 2kg of Quisqualis, 7kg of cashew nuts and 100kg of water are put into a stirred tank, the speed is 120r / min, stirring is continued, heating to boiling, condensing and refluxing, extracting for 2h, and obtaining a pre-extract.

[0028] Step 2), cooling the extract to room temperature, then adding 2g of Streptomyces erythrorhizonii fructose fermentation subspecies, 4g of Lactobacillus mucilaginosus fermentation, and 3g of Pediococcus pentosaceus to the pre-extract, and fermenting at a constant temperature of 33° C. for 7 days to obtain a fermentation product.

[0029] Step 3), the fermented product is filtered through a 200-mesh filter cloth, the filtrate is taken, and the filtrate is filtered through a 0.22 μm filter membrane for sterilization to obtain an extract.

[0030] Step 4), the extract is concentrated to a paste by rotary evaporation, the concentration pressure is 0.01 MPa, the concentration temperature is 55°C, and the paste is dried by powder spraying to obtain a soothing and moisturizing complex.

[0031] Rice was obtained from commercial sources and was dry.

[0032] Cornflower is from commercially available, dried product.

[0033] Quisqualis chinensis is from commercially available, dry product.

[0034] Cashew nuts were sourced from commercially available, dry products.

[0035] Streptomyces erythrorhizogenes fructose fermentation subsp. cinderipes was purchased from Beijing Bio-Bowei Biotechnology Co., Ltd., platform number: Bio-01527.

[0036] Fermented Lactobacillus mucilaginosus was purchased from Beijing Bio-Bowei Biotechnology Co., Ltd., platform number: Bio-84642.

[0037] Pediococcus pentosaceus was purchased from Beijing Biobio Biotechnology Co., Ltd., platform number: Bio-74978.

[0038] Example 2 A soothing and moisturizing complex, the preparation method of the soothing and moisturizing complex is as follows: Step 1), 11kg of rice, 6kg of cornflower, 3kg of Quisqualis, 8kg of cashew nuts, and 125kg of water are put into a stirred tank, the speed is 120r / min, stirring is continued, heating to boiling, condensing and refluxing, extracting for 2.5h, and obtaining a pre-extract.

[0039] Step 2), cooling the extract to room temperature, then adding 2.5g of Streptomyces erythrorhizonii fructose fermentation subspecies, 4.5g of Lactobacillus mucilaginosus fermentation, and 3.5g of Pediococcus pentosaceus to the pre-extract, and fermenting at a constant temperature of 34°C for 8 days to obtain a fermentation product.

[0040] Step 3), the fermented product is filtered through a 200-mesh filter cloth, the filtrate is taken, and the filtrate is filtered through a 0.22 μm filter membrane for sterilization to obtain an extract.

[0041] Step 4), the extract is concentrated to a paste by rotary evaporation, the concentration pressure is 0.01 MPa, the concentration temperature is 55°C, and the paste is dried by powder spraying to obtain a soothing and moisturizing complex.

[0042] Rice was obtained from commercial sources and was dry.

[0043] Cornflower is from commercially available, dried product.

[0044] Quisqualis chinensis is from commercially available, dry product.

[0045] Cashew nuts were sourced from commercially available, dry products.

[0046] Streptomyces erythrorhizogenes fructose fermentation subsp. cinderipes was purchased from Beijing Bio-Bowei Biotechnology Co., Ltd., platform number: Bio-01527.

[0047] Fermented Lactobacillus mucilaginosus was purchased from Beijing Bio-Bowei Biotechnology Co., Ltd., platform number: Bio-84642.

[0048] Pediococcus pentosaceus was purchased from Beijing Biobio Biotechnology Co., Ltd., platform number: Bio-74978.

[0049] Example 3 A soothing and moisturizing complex, the preparation method of the soothing and moisturizing complex is as follows: Step 1), 12kg of rice, 7kg of cornflower, 4kg of Quisqualis, 9kg of cashew nuts and 150kg of water are put into a stirred tank, the speed is 120r / min, stirring is continued, heating to boiling, condensing and refluxing, extracting for 2-3h, and obtaining a pre-extract.

[0050] Step 2), cooling the extract to room temperature, then adding 3g of Streptomyces erythrorhizonii fructose fermentation subspecies, 5g of Lactobacillus mucilaginosus fermentation, and 4g of Pediococcus pentosaceus to the pre-extract, and fermenting at a constant temperature of 35° C. for 9 days to obtain a fermentation product.

[0051] Step 3), the fermented product is filtered through a 200-mesh filter cloth, the filtrate is taken, and the filtrate is filtered through a 0.22 μm filter membrane for sterilization to obtain an extract.

[0052] Step 4), the extract is concentrated to a paste by rotary evaporation, the concentration pressure is 0.01 MPa, the concentration temperature is 55°C, and the paste is dried by powder spraying to obtain a soothing and moisturizing complex.

[0053] Rice was obtained from commercial sources and was dry.

[0054] Cornflower is from commercially available, dried product.

[0055] Quisqualis chinensis is from commercially available, dry product.

[0056] Cashew nuts were sourced from commercially available, dry products.

[0057] Streptomyces erythrorhizogenes fructose fermentation subsp. cinderosa was purchased from Beijing Bio-Bowei Biotechnology Co., Ltd., platform number: Bio-01527.

[0058] Fermented Lactobacillus mucilaginosus was purchased from Beijing Bio-Bowei Biotechnology Co., Ltd., platform number: Bio-84642.

[0059] Pediococcus pentosaceus was purchased from Beijing Biobio Biotechnology Co., Ltd., platform number: Bio-74978.

[0060] Comparative Example 1 A soothing emollient complex, compared with Example 2, the only difference is: Replace rice with an equal amount of Centella asiatica.

[0061] Centella asiatica was purchased from Bozhou Huozhengtang Pharmaceutical Co., Ltd.

[0062] Comparative Example 2 A soothing emollient complex, compared with Example 2, the only difference is: Use an equal amount of Angelica dahurica to replace cornflower.

[0063] Baizhi Anguo City Dinggao local Chinese medicine shop.

[0064] Comparative Example 3 A soothing emollient complex, compared with Example 2, the only difference is: An equal amount of licorice was used to replace Quisqualis chinensis.

[0065] Licorice was purchased from Yunnan Guangkuntang Agricultural Technology Co., Ltd.

[0066] Comparative Example 4 A soothing emollient complex, compared with Example 2, the only difference is: Replace cashews with an equal amount of astragalus.

[0067] Astragalus Jilin Deji Pharmaceutical Co., Ltd.

[0068] Comparative Example 5 A soothing emollient complex, compared with Example 2, the only difference is: Replace rice with an equal amount of Centella asiatica, replace cornflower with an equal amount of Angelica dahurica, replace Quisqualis gentiana with an equal amount of licorice, and replace cashews with an equal amount of Astragalus.

[0069] Centella asiatica was purchased from Bozhou Huozhengtang Pharmaceutical Co., Ltd.

[0070] Baizhi Anguo City Dinggao local Chinese medicine shop.

[0071] Licorice was purchased from Yunnan Guangkuntang Agricultural Technology Co., Ltd.

[0072] Astragalus Jilin Deji Pharmaceutical Co., Ltd.

[0073] Comparative Example 6 A soothing emollient complex, compared with Example 2, the only difference is: Bacillus megaterium was used to replace Streptomyces erythrorhizogenes subsp. fructose fermentation in an equal amount.

[0074] Bacillus megaterium was purchased from Shanghai Biotechnology Collection Center, strain number: SHBCC D50759.

[0075] Comparative Example 7 A soothing emollient complex, compared with Example 2, the only difference is: Lactobacillus acidophilus was used to replace Lactobacillus mucilaginosus fermentation in equal amounts.

[0076] Lactobacillus acidophilus was purchased from Shanghai Collection Biotechnology Center, strain number: SHBCC D24496.

[0077] Comparative Example 8 A soothing emollient complex, compared with Example 2, the only difference is: Kluyveromyces marxianus was used to replace Pediococcus pentosaceus in equal amounts.

[0078] Kluyveromyces marxianus was purchased from Shanghai Collection Biotechnology Center, strain number: SHBCC D53912.

[0079] Comparative Example 9 A soothing emollient complex, compared with Example 2, the only difference is: Bacillus megaterium was used to replace the fructose fermentation subsp. rhodochrophorus, Lactobacillus acidophilus was used to replace the fermentation Lactobacillus mucilaginosus, and Kluyveromyces marxianus was used to replace Pediococcus pentosaceus.

[0080] Bacillus megaterium was purchased from Shanghai Biotechnology Collection Center, strain number: SHBCC D50759.

[0081] Lactobacillus acidophilus was purchased from Shanghai Collection Biotechnology Center, strain number: SHBCC D24496.

[0082] Kluyveromyces marxianus was purchased from Shanghai Collection Biotechnology Center, strain number: SHBCC D53912.

[0083] Experiment 1 According to T / JSRH 003-2023 "Hyaluronidase inhibition method for testing the anti-allergic activity of cosmetic raw materials", the hyaluronidase inhibition rate (%) of the test samples prepared from the soothing and moisturizing complexes of each embodiment and comparative example was tested.

[0084] Sample to be tested: Take 5g of soothing emollient complex and 95g of deionized water, mix well to obtain the sample to be tested.

[0085] Experiment 2 According to T / AHPCA047-2023 "Test Method for Anti-Wrinkle and Firming Efficacy of Cosmetics (Rapid Determination of Elastase Inhibition)", the elastase inhibition rate (%) of the test samples prepared from the soothing and moisturizing complexes of each embodiment and comparative example was tested.

[0086] Sample to be tested: Take 5g of soothing emollient complex and 95g of deionized water, mix well to obtain the sample to be tested.

[0087] The specific experimental data of Experiments 1 and 2 are shown in Table 1.

[0088] Table 1 Hyaluronidase inhibition rate (%) Elastase inhibition rate (%) Example 1 79.93 62.34 Example 2 81.06 63.55 Example 3 80.29 62.97 Comparative Example 1 51.45 41.35 Comparative Example 2 51.13 43.27 Comparative Example 3 52.69 40.56 Comparative Example 4 53.74 42.24 Comparative Example 5 50.19 40.18 Comparative Example 6 60.25 49.91 Comparative Example 7 61.17 48.85 Comparative Example 8 60.93 50.63 Comparative Example 9 59.48 48.24 According to the data comparison of each embodiment and comparative example in Table 1, the hyaluronidase inhibition rate (%) and elastase inhibition rate (%) of each embodiment are significantly higher than those of each comparative example. It can be seen that the complex obtained by fermenting rice, cornflower, Quisqualis creeper and cashew nut with Streptomyces eryngii fructose fermentation subspecies, fermented Lactobacillus mucilaginosus and Pediococcus pentosaceus in each embodiment can give full play to the synergistic compound effect of each active ingredient and the fermentation product, so that the soothing effect is significantly improved, and the effect of restoring skin elasticity is also more significant.

[0089] In Comparative Examples 1-5, rice, cornflower, Quisqualis, and cashew in the embodiments are replaced by other plants with soothing effects alone or in whole. Although they can also have a soothing effect, the soothing effect and the effect of restoring skin elasticity are significantly reduced compared with the embodiments due to the destruction of the system of special active ingredients cooperating with each other. In Comparative Examples 6-9, other fermentation bacteria are used to replace Streptomyces ash redus fructose fermentation subspecies, fermented Lactobacillus mucus, and Pediococcus pentosaceus alone or in whole. Although the soothing effect and the effect of restoring skin elasticity of the fermented complex are better than those of Comparative Examples 1-5, the composite system of Streptomyces ash redus fructose fermentation subspecies, fermented Lactobacillus mucus, and Pediococcus pentosaceus is destroyed, resulting in the failure to produce special fermentation products that cooperate with the active ingredients of rice, cornflower, Quisqualis, and cashew, resulting in the effects of soothing the skin and promoting skin elasticity recovery being significantly lower than those of the embodiments.

[0090] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.

Claims

1. A method for preparing a soothing emollient complex, characterized in that: The following steps are involved: Step 1), mixing rice, cornflower, Quisqualis creeper, cashew nut and water, heating and extracting to obtain a pre-extract; Step 2), adding composite bacteria to the pre-extract, fermenting, and obtaining a fermentation product; Step 3), filtering and sterilizing the fermented product to obtain an extract; Step 4), concentrating and drying the extract to obtain a soothing and moisturizing complex; The composite bacteria is a combination of fructose fermentation subspecies of Streptomyces erythrorhizogenes, fermentation Lactobacillus mucus, and Pediococcus pentosaceus.

2. The method for preparing a soothing and moisturizing complex according to claim 1, characterized in that: The mass ratio of the rice, cornflower, Quisqualis creeper and cashew nut is 10-12:5-7:2-4:7-9.

3. The method for preparing a soothing and moisturizing complex according to claim 2, characterized in that: The mass ratio of the rice, cornflower, quinceanera, cashew nut and water is 10-12:5-7:2-4:7-9:100-150.

4. The method for preparing a soothing and moisturizing complex according to claim 2, characterized in that: The mass ratio of the fructose fermentation subspecies of Streptomyces erythrorhizogenes, the fermentation Lactobacillus mucilaginosus, and the Pediococcus pentosaceus is 2-3:4-5:3-4.

5. The method for preparing a soothing and moisturizing complex according to claim 4, characterized in that: The mass ratio of the rice, cornflower, Quisqualis creeper, cashew nut, Streptomyces erythrorhizon fructose fermentation subspecies, Lactobacillus mucilaginosus fermentation, and Pediococcus pentosaceus is 10-12: 5-7: 2-4: 7-9: 0.002-0.003: 0.004-0.005: 0.003-0.

004.

6. The method for preparing a soothing and moisturizing complex according to claim 1, characterized in that: In the step 1), the mixture is heated to boiling, condensed and refluxed, and extracted for 2-3 hours.

7. The method for preparing a soothing and moisturizing complex according to claim 1, characterized in that: In the step 2), the temperature is kept at 33-35° C. and the fermentation is carried out for 7-9 days.

8. A soothing emollient complex, characterized in that: The soothing and moisturizing complex is prepared by the preparation method of any one of claims 1 to 7.

9. An application of the method for preparing the soothing and moisturizing complex according to claim 8, characterized in that: The soothing and moisturizing complex is added to a skin care product for preparing a skin care product with soothing and moisturizing effects, and the mass content of the soothing and moisturizing complex in the skin care product is 1-10%.