40 results about "Heart Valve Leaflet" patented technology

The disclosure relates to a device that is configured to be implanted on the native leaflet of a heart valve to increase its length and / or thickness and thereby to improve the valve function and reduce regurgitation. The device may include a leaflet section. The leaflet section may include a central member. The central member may include a first portion, a second portion that opposes the first portion, and a base portion disposed between the first portion and the second portion. The first section may extend from the first portion and the second section may extend from the second portion. The device may include one or more engaging members extending from the central member at an angle with respect to the first section and the second section. The second section may be larger than the first section. The leaflet section may define a three-dimensional region or a bulge.

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame. The prosthetic heart valve further having systems for anchoring the upper flared portion of the stent to a posterior portion of the native valve annulus.

To provide methods and apparatuses for bisection of heart valve leaflets using a catheter having a cutting element.SOLUTION: The invention is a device, system, and method for repairing the heart valve function, which may include bisecting native valve leaflets for improved deployment of a prosthetic heart valve in the native valve annulus. The invention may include a catheter having a cutting element shaft with a cutting element configured to puncture a valve leaflet and / or make a controlled cut through the leaflet. The device may have an extendable foot configured to be positioned on an opposite side of the valve leaflet from the cutting element shaft. The device may include magnets to guide the cutting element and / or cutting element shaft in proper alignment with the extendable foot and to hold the elements in place during leaflet bisection.SELECTED DRAWING: Figure 7

To provide a heart valve repair device.SOLUTION: An implantable device or implant includes an anchor portion including one or more anchors coupled to an actuating element. An anchor is configured to attach to one or more leaflets of a native heart valve. An anchor is configured to move between an open position and a closed position. A device or implant includes an indication feature that is movable between an acceptable tension position and an exceeded tension position. When the anchor is attached to a native heart valve leaflet, the indicating feature indicates to a user when an amount of force applied to the anchor portion by the native heart valve leaflet exceeds a preset or predetermined amount of force.SELECTED DRAWING: Figure 69

A method of forming an implantable biomaterial comprising the steps of providing a polyether-diisocyanate prepolymer, reacting the prepolymer with one or more chain extender molecules typically including benzene 1,4-diol to form a mouldable polymer selected from a polyurethane or polyurethane-urea polymer or a polyurethane-urea block copolymer; placing the mouldable polymer into an implantable biomaterial shaped mould, and shaping and curing the mouldable polymer in the implantable biomaterial shaped mould to form the implantable biomaterial. An implantable biomaterial such as a heart valve leaflet is also disclosed.

A system for cutting at least one valve leaflet of a heart valve having multiple valve leaflets includes an elongate shaft, an expandable balloon coupled to the elongate shaft, an expandable framework disposed radially outward of the expandable balloon, and at least one electrode disposed on the expandable framework. The expandable balloon is configured to shift between a deflated configuration and an inflated configuration, and the expandable framework is configured to shift between a collapsed configuration and an expanded configuration. When the expandable framework is in the expanded configuration, the at least one electrode is configured to cut the at least one valve leaflet.

An annuloplasty device is disclosed comprising first and second support rings having a coiled configuration, and respective first and second retention units, the first support ring transitions to the second support ring over a transition section, the transition section is adapted to be arranged at a commissure of the heart valve leaflets, the first and second support rings extend in respective first and second coil planes being essentially perpendicular to the central axis, the transition section bends at least partly along the central axis so that the first coil plane is separated a distance from the second coil plane along the central axis at the transition section.

A system (100) for use with a valve (10) of a heart of a subject includes an anchor (30) and an implant (200) including a wing (220) having a contact surface (222) and an opposite surface (223) opposite the contact surface. The wings define a tip portion (232), a root portion (230), and a flexible element (280q) coupling the tip portion to the root portion. The implant includes an interface (250) at a root portion of the wing. The system includes a delivery tool (150) including a catheter (140) transluminally advanceable to the heart and a shaft (160) disposed within the catheter and engaged with an interface of the implant. Other embodiments are also described.

A system for lacerating heart valve leaflets (20) includes a coronary guidewire (110) and a laceration device including an ablative cutting element (122). A system may include a first guidewire for insertion into a left ventricle and a guide catheter configured to translate along the first guidewire. The guide catheter may include a steering element configured to direct the coronary guidewire toward the coronary artery. The laceration device cooperates with the coronary guidewire to align the ablative cutting element with a nadir of a heart valve leaflet. A method of lacerating heart valve leaflets includes advancing the coronary guidewire into a coronary artery, translating the laceration device along the coronary guidewire to a position adjacent a heart valve leaflet, positioning the ablative cutting element in contact with a nadir of the heart valve leaflet, and lacerating the heart valve leaflet from the nadir to a free edge of the heart valve leaflet.

A suture construction for adjustable fixation of a heart valve leaflet relative to a papillary muscle or other supporting heart tissue is defined by a central body portion having a plurality of longitudinally spaced indexing openings or loops, an anchor structure at a first end of the body portion, and a suturing structure at a second end of the body portion. The anchor structure is secured or coupled to the papillary muscle or supporting heart tissue and the suturing structure is passed through the heart valve leaflet where one of the indexing loops is selectively fixed to the heart valve leaflet to adjustably fix the heart valve leaflet in a desired functional position relative to the supporting heart tissue. The indexing loops of the suture construction prevent unwanted movement of the heart valve leaflet in both directions and are securable in very small incremental positions for proper functional spacing.

A fixation device for securing together leaflets of a heart valve is provided. The fixation device may comprise two plates that are disposed on either side of the tricuspid valve. The plates may be secured to one another by a locking clip, thereby securing the valve leaflets between the plates.

A system (100) for use with a subject heart valve (10) includes an anchor (30) and an implant (200) including wings (220) having a contact surface (222) and an opposing surface (223) opposite the contact surface. The wings define a tip portion (232), a root portion (230), and a bending element (280q) connecting the tip portion to the root portion. The implant includes an interface (250) at the root portion of the wing. The system includes a delivery tool (150) including a catheter (140) transluminally advanceable into the heart and a shaft (160) disposed within the catheter and engaging the interface of the implant. Other embodiments are also described.

This application relates to prosthetic heart valve leaflet coaptation assemblies and methods. Disclosed are prosthetic heart valves and related methods for assembling a prosthetic heart valve including an annular frame and a plurality of leaflets. As one example, the valve includes a plurality of coaptations, each coaptation including an attachment member having a protruding portion, a first coaptation tab of a first leaflet of the plurality of leaflets being disposed adjacent a first side of the protruding portion and directly secured to the attachment member. Each coaptation also includes a second coaptation tab of a second leaflet of the plurality of leaflets being disposed adjacent an opposite second side of the protruding portion and directly secured to the attachment member.

A system comprises an anchor, having an anchor head that defines a forward-torque face and a reverse-torque face. A delivery tool comprises a transluminally advanceable driver, comprising a driveshaft, and a distal drive head. The drive head is shaped to engage the anchor head such that while the driveshaft presses the drive head distally into engagement with the anchor head, forward rotation of the drive head screws the anchor into the tissue. Reverse rotation of the drive head hooks the drive head onto the anchor head. While the drive head remains hooked onto the anchor head, reverse rotation of the drive head, and pulling the anchor head by tensioning of the driveshaft, unscrews the anchor from the tissue. Tensioning the driveshaft while the drive head is not hooked onto the anchor head pulls the drive head away from the anchor head. Other embodiments are also disclosed.

A medical assembly includes a guide catheter having a lumen extending therethrough and an electrocautery member slidingly disposed within the lumen. The electrocautery member has an elongate shaft having a proximal shaft segment and a distal shaft segment adapted to be movable between a puncture position and an incise position. In some cases, a hinge segment is disposed between the proximal shaft segment and the distal shaft segment and includes a leading edge adapted to form a puncture within a heart valve leaflet when the distal shaft segment is in its puncture position and a trailing edge adapted to incise the heart valve leaflet when the distal shaft segment is in its incise position. In some cases, the electrocautery member includes electrically isolated puncture and incise electrodes.

The invention belongs to the technical field of medical instruments and discloses a valve leaflet clamping device which comprises a catheter component, a driving mechanism, a first clamping arm, a second clamping arm and an auxiliary clamping component, the driving mechanism comprises a handle assembly and a driving assembly, the driving assembly is connected to the handle assembly and penetrates through the catheter component, the first clamping arm is arranged at the far end of the catheter component, and the second clamping arm is arranged at the far end of the catheter component. The second clamping arm is connected to the first clamping arm, the driving assembly drives the second clamping arm to be opened or closed, the second clamping face of the second clamping arm can make contact with the first clamping face of the first clamping arm, the auxiliary clamping component is assembled on the first clamping arm, and when the second clamping arm is opened, the driving assembly drives the auxiliary clamping component to move towards the second clamping arm. The auxiliary clamping part of the auxiliary clamping component can abut against the second clamping face. By applying the technical scheme, the problems that in the heart valve leaflet repairing operation, when a native valve leaflet is clamped, due to the fact that the native valve leaflet is prone to slipping, clamping is difficult, operation is repeated, the operation time is prolonged, and the operation risk is increased are solved.

An annuloplasty device comprises first and second support rings having a coiled configuration in which the first and second support rings are arranged as a coil around a central axis, wherein the first and second support rings are configured to be arranged on opposite sides of native heart valve leaflets of a heart valve, a stent arranged around at least a portion of the first and / or second support ring, and wherein the stent comprises retention units. A related method of repairing a defective heart valve is also disclosed.

The invention relates to a prosthetic heart valve leaflet assembly and a method of assembly. A leaflet assembly for a prosthetic heart valve is disclosed. As one example, a method includes forming a plurality of leaflet assemblies, each including a leaflet and a skirt and formed by arranging the skirt on one side of the leaflet such that the skirt extends along a curvilinear apex edge portion of the leaflet and two commissure lugs, folding two ends of the skirt around the respective commissure lugs, each folded end is sewed to a respective commissure lug to form a corresponding half commissure portion, and the skirt is sewed to the tip edge portion, and forming the leaflet assembly by pairing each half-commissure portion of each leaflet assembly with a half-commissure portion of another leaflet assembly to form a plurality of pairs of adjacent half-commissure portions and stitching the adjacent half-commissure portions to each other for each pair to form a commissure.

Devices and methods for removing a valve clip which is pre-positioned on a heart leaflet, the valve clip including a delivery catheter having a distal end portion configured to be positioned near a heart valve; a grasping tool deployable from the distal end portion of the delivery catheter, the grasping tool configured to grasp and manipulate a valve clip from an implanted condition to an elongated condition, wherein the valve clip in the elongated condition has an elongated width less than an implanted width of the valve clip in the implanted condition; and a removal tool extendable relative to the distal end portion of the delivery catheter, the removal tool configured to at least partially surround the valve clip in the elongated condition and to remove the valve clip from the heart valve leaflet.

In one example, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. A size of the spacer body is configured to be adjusted after the spacer body is placed between the native valve leaflets and the pair of anchors are placed against the ventricular surfaces of the native heart valve leaflets. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.

A system for implanting two or more implants into a heart of a patient may include a multi-device steerable guide catheter ("MDSGC"), a transcatheter edge-to-edge repair ("TEER") implant delivery device, and an additional implant delivery device for implanting an additional medical device. The additional medical device may be a collapsible and expandable prosthetic transcatheter aortic valve repair ("TAVR") device or a collapsible and expandable left atrial appendage ("LAA") occluder device. The MDSGC may have a first handle and may be steerable, the TEER delivery device may have a second handle, and the additional delivery device may have an additional handle. The system may include a fixation device to capture native heart valve leaflets therebetween as part of a TEER procedure. The TEER delivery device and the additional delivery device may each have a catheter sized and shaped to pass through an interior of a catheter of the MDSGC.

A method of repairing a defective heart valve involves positioning first and second support rings of an annuloplasty device in a first configuration on opposite sides of native heart valve leaflets and activating a contracted state of the annuloplasty device so that a first pitch distance between the first and second support rings in the first configuration is reduced to a second pitch distance that is shorter than the first pitch distance to move the first and second support rings toward each other to pinch the native heart valve leaflets.

A transcatheter heart valve leaflet replacement system includes a valve prosthesis and a multi-stage, multi-lumen (MSML) heart valve delivery and implantation system for guiding and implanting the prosthesis to a native annulus. The prosthesis includes a stent frame including an upper atrial flared portion and a lower ventricular portion, a plurality of prosthetic leaflets, and at least one lining skirt. The prosthesis is configurable or otherwise sizable to fit in the MSML delivery and implantation system and to subsequently be selectively expanded to an operative size and position once deployed within the annulus. A portion of the prosthesis can be configured to couple with dual guiding and fixation (DGF) members to guide and fix the prosthesis to the annulus. In one aspect, the MSML delivery and implantation system includes a main docking system, a DGF member delivery system, and a valve housing, positioning, and locking system.

Implant (10) for a heart valve comprising two leaflets, particularly a mitral valve (MV), the implant (10) comprising: a clamp (11) comprising a body (13) and a jaw (14) rotationally hinged with the body (13) to pivot between an open position and a closed position in which the body (13) and the jaw (14) are able to clamp a first leaflet among the heart valve leaflets, so as to attach the implant (10) onto the first leaflet,a movement device (41, 42) comprising a pusher element (41), the movement device being configured to move the jaw (14) relative to the body (13) from the open position to the closed position or vice versa, when the pusher element (41) is pushed by a rod (101), and a balloon (12) attached to the clamp (11) and configured to close at least partially an open portion (O1) remaining between the heart valve (MV) leaflets during systole, when the implant (10) is attached to the first leaflet, so as to limit a reflux of blood through said open portion (O1) remaining during systole.

A suture construction for adjustable fixation of a heart valve leaflet relative to a papillary muscle or other supporting heart tissue is defined by a central body portion having a plurality of longitudinally spaced indexing openings or loops, an anchor structure at a first end of the body portion, and a suturing structure at a second end of the body portion. The anchor structure is secured or coupled to the papillary muscle or supporting heart tissue and the suturing structure is passed through the heart valve leaflet where one of the indexing loops is selectively fixed to the heart valve leaflet to adjustably fix the heart valve leaflet in a desired functional position relative to the supporting heart tissue. The indexing loops of the suture construction prevent unwanted movement of the heart valve leaflet in both directions and are securable in very small incremental positions for proper functional spacing.

A cardiac cutter for cutting valve leaflets provides a main catheter adapted for femoral insertion into a patient's vasculature in an over-the-wire method. The main catheter is deployable within a patient's heart and has a proximal bridge tube and a distal bridge tube with a cutting wire extending between them, the proximal bridge tube, distal bridge tube, and cutting wire together forming a bridge extending outwardly from the main catheter. The cutting wire is configured to cut cardiac valve leaflets using a reciprocal motion or rotating motion, and is operable by a controller. The cutting wire is threaded through a foot positioned between the proximal bridge tube and distal bridge tube. The foot aids in the positioning of the cutting wire against a leaflet to be cut. A commissure guide tube extends from the main catheter opposite from the cutting wire and serves to stabilize the cutter within the valve.

A system for lacerating heart valve leaflets includes a coronary guidewire and a laceration device including an ablative cutting element. A system may include a first guidewire for insertion into a left ventricle and a guide catheter configured to translate along the first guidewire. The guide catheter may include a steering element configured to direct the coronary guidewire toward the coronary artery. The laceration device cooperates with the coronary guidewire to align the ablative cutting element with a nadir of a heart valve leaflet. A method of lacerating heart valve leaflets includes advancing the coronary guidewire into a coronary artery, translating the laceration device along the coronary guidewire to a position adjacent a heart valve leaflet, positioning the ablative cutting element in contact with a nadir of the heart valve leaflet, and lacerating the heart valve leaflet from the nadir to a free edge of the heart valve leaflet.

The invention belongs to the technical field of medical instruments, and particularly relates to a valve leaflet enhancing device which comprises a catheter component, a driving mechanism, a clamping assembly, an artificial valve leaflet and a puncture assembly, the driving mechanism comprises a handle assembly and a driving assembly, the clamping assembly comprises a first clamping arm and a second clamping arm, and the first clamping arm is provided with a first clamping face; the second clamping arm is provided with a second clamping face matched with the first clamping face, the artificial valve leaflet is detachably connected to the second clamping arm, and the puncture assembly comprises a first puncture structure and a second puncture structure. When the second clamping arm is closed, the first puncture structure is in puncture connection with the middle area of the native valve leaflet and the middle area of the artificial valve leaflet, and then when the second clamping arm, the artificial valve leaflet and the native valve leaflet are opened together, the second puncture structure is in puncture connection with the side edge area, located on at least one side of the two sides of the second clamping arm, of the native valve leaflet and the artificial valve leaflet. Therefore, the problem that blood regurgitation is caused due to the fact that the side edge areas of the original valve leaflet and the artificial valve leaflet cannot be stably attached after an existing heart valve leaflet repairing operation is solved.

A method for heart valve treatment includes providing a first heart valve treatment member movable along a first shaft portion, providing a second heart valve treatment member movable along a second shaft portion. The first and second heart valve treatment members are movable along the first and second shaft portions, respectively. The first heart valve treatment member is positioned on one side of a heart valve leaflet and the second heart valve treatment member is positioned on an opposite side of the heart valve leaflet. A portion of the heart valve leaflet is fracture by movement of the first heart valve treatment member with respect to the second heart valve treatment member.

A heart valve prosthesis is provided that includes a first member and a second member. The first member comprises a first central portion to be disposed adjacent to a line of coaptation on a first side of two adjacent heart leaflets and peripheral portions to be placed into direct contact with the two adjacent heart leaflets. The second member is separate from or can be separable from the first member, for example during delivery. The second member has a central portion and peripheral portions configured to be placed into direct contact with a second side of the two adjacent heart leaflets.