19 results about "Heart Valve Leaflet" patented technology

A method of forming an implantable biomaterial comprising the steps of providing a polyether-diisocyanate prepolymer, reacting the prepolymer with one or more chain extender molecules typically including benzene 1,4-diol to form a mouldable polymer selected from a polyurethane or polyurethane-urea polymer or a polyurethane-urea block copolymer; placing the mouldable polymer into an implantable biomaterial shaped mould, and shaping and curing the mouldable polymer in the implantable biomaterial shaped mould to form the implantable biomaterial. An implantable biomaterial such as a heart valve leaflet is also disclosed.

A system for cutting at least one valve leaflet of a heart valve having multiple valve leaflets includes an elongate shaft, an expandable balloon coupled to the elongate shaft, an expandable framework disposed radially outward of the expandable balloon, and at least one electrode disposed on the expandable framework. The expandable balloon is configured to shift between a deflated configuration and an inflated configuration, and the expandable framework is configured to shift between a collapsed configuration and an expanded configuration. When the expandable framework is in the expanded configuration, the at least one electrode is configured to cut the at least one valve leaflet.

A system for lacerating heart valve leaflets (20) includes a coronary guidewire (110) and a laceration device including an ablative cutting element (122). A system may include a first guidewire for insertion into a left ventricle and a guide catheter configured to translate along the first guidewire. The guide catheter may include a steering element configured to direct the coronary guidewire toward the coronary artery. The laceration device cooperates with the coronary guidewire to align the ablative cutting element with a nadir of a heart valve leaflet. A method of lacerating heart valve leaflets includes advancing the coronary guidewire into a coronary artery, translating the laceration device along the coronary guidewire to a position adjacent a heart valve leaflet, positioning the ablative cutting element in contact with a nadir of the heart valve leaflet, and lacerating the heart valve leaflet from the nadir to a free edge of the heart valve leaflet.

A suture construction for adjustable fixation of a heart valve leaflet relative to a papillary muscle or other supporting heart tissue is defined by a central body portion having a plurality of longitudinally spaced indexing openings or loops, an anchor structure at a first end of the body portion, and a suturing structure at a second end of the body portion. The anchor structure is secured or coupled to the papillary muscle or supporting heart tissue and the suturing structure is passed through the heart valve leaflet where one of the indexing loops is selectively fixed to the heart valve leaflet to adjustably fix the heart valve leaflet in a desired functional position relative to the supporting heart tissue. The indexing loops of the suture construction prevent unwanted movement of the heart valve leaflet in both directions and are securable in very small incremental positions for proper functional spacing.

A fixation device for securing together leaflets of a heart valve is provided. The fixation device may comprise two plates that are disposed on either side of the tricuspid valve. The plates may be secured to one another by a locking clip, thereby securing the valve leaflets between the plates.

A medical assembly includes a guide catheter having a lumen extending therethrough and an electrocautery member slidingly disposed within the lumen. The electrocautery member has an elongate shaft having a proximal shaft segment and a distal shaft segment adapted to be movable between a puncture position and an incise position. In some cases, a hinge segment is disposed between the proximal shaft segment and the distal shaft segment and includes a leading edge adapted to form a puncture within a heart valve leaflet when the distal shaft segment is in its puncture position and a trailing edge adapted to incise the heart valve leaflet when the distal shaft segment is in its incise position. In some cases, the electrocautery member includes electrically isolated puncture and incise electrodes.

The invention belongs to the technical field of medical instruments and discloses a valve leaflet clamping device which comprises a catheter component, a driving mechanism, a first clamping arm, a second clamping arm and an auxiliary clamping component, the driving mechanism comprises a handle assembly and a driving assembly, the driving assembly is connected to the handle assembly and penetrates through the catheter component, the first clamping arm is arranged at the far end of the catheter component, and the second clamping arm is arranged at the far end of the catheter component. The second clamping arm is connected to the first clamping arm, the driving assembly drives the second clamping arm to be opened or closed, the second clamping face of the second clamping arm can make contact with the first clamping face of the first clamping arm, the auxiliary clamping component is assembled on the first clamping arm, and when the second clamping arm is opened, the driving assembly drives the auxiliary clamping component to move towards the second clamping arm. The auxiliary clamping part of the auxiliary clamping component can abut against the second clamping face. By applying the technical scheme, the problems that in the heart valve leaflet repairing operation, when a native valve leaflet is clamped, due to the fact that the native valve leaflet is prone to slipping, clamping is difficult, operation is repeated, the operation time is prolonged, and the operation risk is increased are solved.

Devices and methods for removing a valve clip which is pre-positioned on a heart leaflet, the valve clip including a delivery catheter having a distal end portion configured to be positioned near a heart valve; a grasping tool deployable from the distal end portion of the delivery catheter, the grasping tool configured to grasp and manipulate a valve clip from an implanted condition to an elongated condition, wherein the valve clip in the elongated condition has an elongated width less than an implanted width of the valve clip in the implanted condition; and a removal tool extendable relative to the distal end portion of the delivery catheter, the removal tool configured to at least partially surround the valve clip in the elongated condition and to remove the valve clip from the heart valve leaflet.

In one example, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. A size of the spacer body is configured to be adjusted after the spacer body is placed between the native valve leaflets and the pair of anchors are placed against the ventricular surfaces of the native heart valve leaflets. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.

A system for implanting two or more implants into a heart of a patient may include a multi-device steerable guide catheter ("MDSGC"), a transcatheter edge-to-edge repair ("TEER") implant delivery device, and an additional implant delivery device for implanting an additional medical device. The additional medical device may be a collapsible and expandable prosthetic transcatheter aortic valve repair ("TAVR") device or a collapsible and expandable left atrial appendage ("LAA") occluder device. The MDSGC may have a first handle and may be steerable, the TEER delivery device may have a second handle, and the additional delivery device may have an additional handle. The system may include a fixation device to capture native heart valve leaflets therebetween as part of a TEER procedure. The TEER delivery device and the additional delivery device may each have a catheter sized and shaped to pass through an interior of a catheter of the MDSGC.

A method of repairing a defective heart valve involves positioning first and second support rings of an annuloplasty device in a first configuration on opposite sides of native heart valve leaflets and activating a contracted state of the annuloplasty device so that a first pitch distance between the first and second support rings in the first configuration is reduced to a second pitch distance that is shorter than the first pitch distance to move the first and second support rings toward each other to pinch the native heart valve leaflets.

A suture construction for adjustable fixation of a heart valve leaflet relative to a papillary muscle or other supporting heart tissue is defined by a central body portion having a plurality of longitudinally spaced indexing openings or loops, an anchor structure at a first end of the body portion, and a suturing structure at a second end of the body portion. The anchor structure is secured or coupled to the papillary muscle or supporting heart tissue and the suturing structure is passed through the heart valve leaflet where one of the indexing loops is selectively fixed to the heart valve leaflet to adjustably fix the heart valve leaflet in a desired functional position relative to the supporting heart tissue. The indexing loops of the suture construction prevent unwanted movement of the heart valve leaflet in both directions and are securable in very small incremental positions for proper functional spacing.

A system for lacerating heart valve leaflets includes a coronary guidewire and a laceration device including an ablative cutting element. A system may include a first guidewire for insertion into a left ventricle and a guide catheter configured to translate along the first guidewire. The guide catheter may include a steering element configured to direct the coronary guidewire toward the coronary artery. The laceration device cooperates with the coronary guidewire to align the ablative cutting element with a nadir of a heart valve leaflet. A method of lacerating heart valve leaflets includes advancing the coronary guidewire into a coronary artery, translating the laceration device along the coronary guidewire to a position adjacent a heart valve leaflet, positioning the ablative cutting element in contact with a nadir of the heart valve leaflet, and lacerating the heart valve leaflet from the nadir to a free edge of the heart valve leaflet.

The invention belongs to the technical field of medical instruments, and particularly relates to a valve leaflet enhancing device which comprises a catheter component, a driving mechanism, a clamping assembly, an artificial valve leaflet and a puncture assembly, the driving mechanism comprises a handle assembly and a driving assembly, the clamping assembly comprises a first clamping arm and a second clamping arm, and the first clamping arm is provided with a first clamping face; the second clamping arm is provided with a second clamping face matched with the first clamping face, the artificial valve leaflet is detachably connected to the second clamping arm, and the puncture assembly comprises a first puncture structure and a second puncture structure. When the second clamping arm is closed, the first puncture structure is in puncture connection with the middle area of the native valve leaflet and the middle area of the artificial valve leaflet, and then when the second clamping arm, the artificial valve leaflet and the native valve leaflet are opened together, the second puncture structure is in puncture connection with the side edge area, located on at least one side of the two sides of the second clamping arm, of the native valve leaflet and the artificial valve leaflet. Therefore, the problem that blood regurgitation is caused due to the fact that the side edge areas of the original valve leaflet and the artificial valve leaflet cannot be stably attached after an existing heart valve leaflet repairing operation is solved.

A heart valve prosthesis is provided that includes a first member and a second member. The first member comprises a first central portion to be disposed adjacent to a line of coaptation on a first side of two adjacent heart leaflets and peripheral portions to be placed into direct contact with the two adjacent heart leaflets. The second member is separate from or can be separable from the first member, for example during delivery. The second member has a central portion and peripheral portions configured to be placed into direct contact with a second side of the two adjacent heart leaflets.

The disclosure includes methods, systems and devices for severing and optionally removing at least a portion of heart valve leaflets. Leaflets can be partially removed or entirely removed or otherwise, the leaflets can be severed or splayed in such a way as to avoid coronary blockage, LVOT obstruction, or access challenges in procedures where a prosthetic valve is to be implanted within a previously implanted prosthetic valve. The disclosure also relate to numerous devices for and methods of disabling one or more valve ligating devices to provide an unobstructed valve opening so that a prosthetic heart valve can be implanted within the opening. The ligation device(s) is disabled either by removing the ligation device(s) or severing one leaflet so that ligated leaflets can be separated. In some embodiments, the ligation device(s) are severed to disable the ligation device(s).

A fixation device for fixation of heart valve leaflets includes a central assembly and an arm moveably coupled to the central assembly. The arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween. The body portion has opposing body lateral sides, each body lateral side extending between the first end and the second end. Further, the body portion has a body portion width defined between the opposing body lateral sides. The fixation device further includes a size adapter attached to the arm, the size adapter having a maximum undeformed arm lateral cross-dimension defined between outer lateral edges of the size adapter. The ratio between the body portion width and the maximum undeformed arm lateral cross-dimension is at least about 1:1.8 to about 1:2.2. The fixation device further includes at least one gripping element.

A method of forming an implantable biomaterial comprising the steps of providing a polyether-diisocyanate prepolymer, reacting the prepolymer with one or more chain extender molecules typically including benzene 1,4-diol to form a mouldable polymer selected from a polyurethane or polyurethane-urea polymer or a polyurethane-urea block copolymer; placing the mouldable polymer into an implantable biomaterial shaped mould, and shaping and curing the mouldable polymer in the implantable biomaterial shaped mould to form the implantable biomaterial. An implantable biomaterial such as a heart valve leaflet is also disclosed.

A system for annuloplasty is disclosed comprising an annuloplasty device comprising first and second support rings having a coiled configuration in which the first and second support rings are arranged as a coil around a central axis, wherein the first and second support rings are configured to be arranged on opposite sides of native heart valve leaflets of a heart valve, a line attached to the first and / or second support ring, and a heating element configured to be heated upon receiving a supply of energy, wherein the heating element is positionable to heat and sever the line upon the heating element receiving said energy.