405 results about "Ventricular assistance" patented technology

The present disclosure relates to a method for detecting a state of wear of a cardiac support system. The method comprises a read-in step and a determination step. During the read-in step, a sensor signal representing an operating state of the cardiac support system is read in. During the determination step, a wear signal is determined using the sensor signal and a comparison rule. The wear signal represents the wear condition.

Apparatus and methods are described including a ventricular assist device that includes a tube configured to traverse a subject's aortic valve. The tube defines a generally-cylindrical central portion, and a proximal conical portion that narrows from a proximal end of the central portion to a proximal end of the tube. The tube defines one or more blood inlet openings in a vicinity of a distal end of the tube, and one or more blood outlet openings that extend axially from the central portion of the tube at least partially into the proximal conical portion of the tube. A blood pump pumps blood into the tube from the subject's left ventricle through the one or more blood inlet openings, and from the tube into the aorta through the one or more blood outlet openings. Other applications are also described.

The invention relates to a method for operating an implanted, ventricular assist system (2), comprising the following steps: a) determine a first impedance parameter at a first point in time by means of the assist system (2), b) determine a second impedance parameter at a second point in time by means of the assist system (2), c) at least determine a change of the impedance parameter using the first impedance parameter and the second impedance parameter, or compare at least the first or second impedance parameter to a threshold value.

Apparatus and methods are described including a ventricular assist device that includes a frame having struts that define a plurality of cells. In its non-radially-constrained configuration, the frame includes a generally cylindrical portion. A tube defines blood outlet openings, and a portion of the tube is disposed outside the frame and is coupled to the generally cylindrical portion of the frame, such that the portion of the tube conforms with a structure of struts of the frame. An inner lining is coupled to an inside of the generally cylindrical portion of the frame, such as to provide the generally cylindrical portion of the frame with a smooth inner surface. An impeller is disposed at least partially inside the generally cylindrical portion of the frame and is configured to pump blood through the tube and out of the one of more blood outlet openings. Other applications are also described.

The invention provides a driving control mechanism which is applied to a left ventricle assisting device, the left ventricle assisting device further comprises a transmission shaft, the driving control mechanism comprises a shell, a twisting shell driving module and a mandrel driving module, the twisting shell driving module and the mandrel driving module are sequentially arranged in the shell, and the far end of the twisting shell driving module is in transmission connection with a twisting shell of the transmission shaft. The far end of the mandrel driving module is in transmission connection with a mandrel of the transmission shaft and is detachably connected with the near end of the twisting shell driving module. When the far end of the mandrel driving module is connected with the near end of the twisting shell driving module, the mandrel driving module drives the mandrel and the twisting shell to rotate synchronously. When the far end of the mandrel driving module is separated from the near end of the twisting shell driving module, the twisting shell driving module drives the twisting shell to rotate relative to the mandrel. According to the driving control mechanism, synchronous or relative rotation of the mandrel and the twisting shell can be achieved, then folding, unfolding and rotating movement of a pump head impeller in the left ventricle auxiliary device is achieved, and the use efficiency and safety of the left ventricle auxiliary device are improved.

The invention relates to an electronics module (102) for a ventricular assist device, wherein the ventricular assist device has a motor housing for accommodating a pump motor. The electronics module (102) comprises an electronics section (204) for accommodating at least one electronic component (206) and / or at least one electrically conductive contacting element (208), and a coupling section (202) designed as a joint between the motor housing (104) and the electronics section (204) or as a separate component to be joined, wherein the motor housing (104) and the electronics section (204) are combined or can be combined via the coupling section (202) with one another to form a fluid-tight module housing (104) to be arranged in a blood vessel.

Apparatus and methods are described including delivering a left-ventricular assist device to a subject's aorta. The device including a distal-tip element that defines a straight proximal portion, and a curved distal portion, the curved distal portion defining first and second curves with an elongated straight portion between the first and second curves. The distal-tip element is centered with respect to the aortic valve using the curved distal portion of the distal-tip element, to thereby guide the device through the subject's aortic valve atraumatically. A pump pumps blood through from the subject's left ventricle to the subject's aorta. Other applications are also described.

Apparatus and methods are described including delivering a left-ventricular assist device to a subject's left ventricle. A tube is positioned such that a proximal portion of the tube traverses an aortic valve of the subject, and a distal portion of the tube is disposed within a left ventricle of the subject. A pump pumps blood through the tube from the subject's left ventricle to the subject's aorta such as to cause the proximal portion of the tube to be maintained in an open state, and to cause at least a portion of the tube to become curved. Other applications are also described.

The invention relates to the technical field of heart blood pumps, in particular to a passive ventricular auxiliary circulation device. Comprising a motor body shell, a stator and a rotor are arranged in the motor body shell, and one of the stator and the rotor comprises a coil; the axial flow channel shell is sleeved; the upper end of the axial flow channel shell is configured to face the aortic valve to the lower part of the ventricle, and a power supply configured to be operably coupled to the coil; and the controller is configured to be operated and coupled to the power supply to select and control the power supply to change the rotor to a certain rotating speed in a manual selection mode, then the rotor keeps working in a certain rotating speed mode, and corresponding auxiliary pressure output by the fluid outlet interface is configured at a different rotating speed. The device is controlled to be in a rotating speed state, and when systolic pressure smaller than normal systolic pressure is provided for cardiac pulsation of a heart failure patient, the normal systolic pressure is provided when the systolic pressure and auxiliary pressure are overlapped together, so that the heart failure patient maintains the normal systolic pressure.

Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject. A driving magnet is coupled to a motor and is rotated by the motor. A driven magnet is magnetically coupled to the driving magnet and is rotated by the driving magnet. A drive cable extends from the driven magnet and imparts rotational motion from the driven magnet to the impeller. A set of sensors is configured to detect a magnetic phase difference between the driven magnet and the driving magnet. A computer processor receives the detected magnetic phase difference and determines a physiological parameter of the subject, at least partially in response thereto. Other applications are also described.

The invention provides a preparation method of a left ventricular assist device, the left ventricular assist device comprises a micro pump head, a transmission shaft and a driving control mechanism, the micro pump head comprises a pump head impeller and a pump head transmission assembly, the transmission shaft comprises a mandrel and a twisting shell, and the driving control mechanism comprises a twisting shell driving module and a mandrel driving module. The method comprises the following steps that a pump head transmission assembly penetrates through a pump head impeller, and the far end and the near end of the pump head impeller are fixed to the far end of the pump head transmission assembly and the far end of a twisting shell correspondingly; a mandrel is inserted into the twisting shell, and the far end of the mandrel and the near end of the pump head transmission assembly are fixed; the twisting shell driving module is arranged at the far end of the mandrel driving module and is detachably connected with the mandrel driving module, and the far end of the twisting shell driving module is in transmission connection with the near end of the twisting shell; and the far end of the mandrel driving module is in transmission connection with the near end of the mandrel. According to the scheme, the left ventricle auxiliary device with the instrument micro-size and the high blood supply flow can be obtained, and the use safety and the working efficiency of the left ventricle auxiliary device are improved.

The invention relates to an apparatus (100) for anchoring a ventricular assist system in a blood vessel, the apparatus (100) being able to assume an insertion state for insertion of the ventricular assist system into the blood vessel, and the apparatus (100) being able to assume an anchoring state in order to anchor the ventricular assist system in the blood vessel. The apparatus (100) has at least one fixing means (105) for fixing the apparatus (100) to the ventricular assist system (205), a crown (110) and a connection means (115). The crown (110) is formed from at least one unfolding element (120). The unfolding element (120) is designed to unfold during the transfer from the insertion state into the anchoring state in order to enlarge the diameter of the crown (110) so as to anchor the apparatus (100) in the blood vessel. The connection means (115) is designed to connect the crown (110) to the fixing means (105).

The invention relates to the technical field of heart blood pumps, in particular to a valve and pump integrated tandem type ventricular auxiliary circulation device. Comprising a ventricular auxiliary circulating pump device and a ventricular auxiliary circulating valve device, the ventricular auxiliary circulating pump device is provided with an axial flow channel shell (3) and a power part arranged in the axial flow channel shell (3); the ventricular auxiliary circulation valve device is provided with a tubular metal support body (100), and the metal support body comprises a plurality of longitudinal supporting columns; the upper end of the axial flow channel shell (3) is provided with a flanging part (31) which is outward in the radial direction, and the longitudinal supporting column lower tail end (101) of the longitudinal supporting column is assembled, contacted and fixed to the flanging part (31). A supporting system and a heat dissipation system are constructed to be of the same path structure, and the heat dissipation effect is improved on the basis that the structure is reduced.

The invention provides a left ventricle auxiliary device which comprises a driving control mechanism, a left ventricle auxiliary device, a left ventricle auxiliary device and a right ventricle auxiliary device. The transmission shaft comprises a twisting shell and a mandrel, and the twisting shell is movably arranged outside the mandrel in a sleeving mode; the micro pump head comprises a pump head impeller and a pump head transmission assembly, the near end of the pump head impeller is in transmission connection with the twisting shell driving module through a twisting shell, the far end of the pump head transmission assembly is fixedly connected with the far end of the pump head impeller, and the near end of the pump head transmission assembly is in transmission connection with the mandrel driving module through a mandrel. The mandrel driving module drives the mandrel and the twisting shell to rotate synchronously so as to drive the far end and the near end of the pump head impeller to rotate together, so that the pump head impeller rotates at a fixed outer diameter; and the twisting shell driving module drives the twisting shell and the mandrel to rotate relatively so as to drive the near end of the pump head impeller to rotate relative to the far end, so that the pump head impeller is folded or unfolded. According to the scheme, the outer diameter of the micro pump head in the left ventricle auxiliary device can be adjusted, so that the use efficiency and safety of the micro pump head are improved.

The invention provides a self-adaptive control method and device. The method comprises the steps that multiple pumping flows of a ventricular assist device during operation at a first rotating speed in a first period are obtained; first duration and second duration are recorded, the first duration is the duration of the interval between the adjacent first pumping flow, the second duration is the duration from the first pumping flow to the pumping flow smaller than a first flow threshold value in the first duration, and the first pumping flow is the peak value of the pumping flow of the ventricular assist device; if the first rotating speed is adjusted according to the target ratio, the target ratio is the ratio of the second duration to the first duration. The cardiac cycle of the user and the low flow value of the ventricular assist device can be determined according to the first duration and the second duration respectively, and the rotating speed of the ventricular assist device is adaptively adjusted according to the ratio of the second duration to the first duration, so that the pumping flow of the ventricular assist device can meet the requirements of the user in real time; abnormalities of the ventricular auxiliary device are reduced, and therefore the safety of a user is improved.

The invention provides a ventricular assist device control device and method, a ventricular assist system and electronic equipment, and relates to the field of medical instrument control. The control device comprises a time sequence judgment module, a characteristic flow calculation module and a motor control module. The time sequence judgment module is used for dividing the target cardiac cycle into a systolic stage and a diastolic stage; the characteristic flow calculation module is used for dividing the real-time flow of the ventricular assist device in the target cardiac cycle into systolic period flow in a systolic period stage and / or diastolic period flow in a diastolic period stage, and calculating the characteristic cardiac output of the ventricular assist device in the target cardiac cycle according to the systolic period flow and the diastolic period flow; the motor control module is used for adjusting motor rotation speed. By using the control device provided by the embodiment of the invention, the cardiac output of the ventricular auxiliary device can better conform to the physiological law of the heart, and stable control of the cardiac output is realized.

A control device (100) for controlling the rotational speed (nVAD(t)) of a non-pulsatile ventricular assist device, VAD, (50) uses an event-based within-a-beat control strategy, wherein the control device is configured to alter the rotational speed of the VAD within the cardiac cycle of the assisted heart and to synchronize the alteration of the rotational speed with the heartbeat by at least one sequence of trigger signals (σ(t)) that is related to at least one predetermined characteristic event in the cardiac cycle. Further, a VAD (50) for assistance of a heart comprises the control device (100) for controlling the VAD, wherein the VAD is preferably a non-pulsatile rotational, for example catheter-based, blood pump.

A two-way valve and a pulsatile percutaneous ventricular assist device using same. The two-way valve comprises: a valve body (1) with an inner cavity (10) passing through, the inner cavity being provided with a proximal port (1a) and a distal port (1b), and the valve body (1) being provided with an open window (1c) in communication with the inner cavity (10) and the outside of the valve body (1); and a valve flap (2) arranged in the inner cavity (10) and rotationally connected to the valve body (1), the valve flap (2) comprising a first valve leaf (21), a second valve leaf (22), and a third valve leaf (23), which are connected at an obtuse angle, the first valve leaf (21) being arranged at the open window (1c), the second valve leaf (22) being arranged on one side close to the inner cavity (10) at one end of the first valve leaf (21) close to the proximal port (1a), and the third valve leaf (23) being arranged on one side close to the inner cavity at one end of the first valve leaf close to the distal port (1b). The valve flap (2) is impacted by blood flow axially flowing in the inner cavity (10) and is rotationally switched back and forth between an open position and a closed position. In the open position, the three valve leaves together partition the proximal port (1a) and the distal port (1b), and the open window (1c) is opened and in communication with the distal port (1b). In the closed position, the first valve leaf (21) closes the open window (1c), and the proximal port (1a) is in communication with the distal port (1b), thereby achieving better switching response and sealing effects.

The invention discloses a ventricular assist system, a flushing method of a medical catheter pump system, consumables and a device, and belongs to the technical field of medical equipment. The ventricular assist system comprises a flushing pump assembly (210), a first three-way valve (220), a second three-way valve (230) and a medical catheter pump (240), a first valve port (221) of the first three-way valve (220) is connected to a first flushing passage driven by the flushing pump assembly (210), and a second valve port (222) of the first three-way valve (220) is connected to a first flushing interface of the medical catheter pump (240); a first valve port (231) of the second three-way valve (230) is connected to a second flushing passage driven by the flushing pump assembly (210), and a second valve port (232) of the second three-way valve (230) is connected to a second flushing interface of the medical catheter pump (240).

The invention relates to an adapter, a connecting assembly and a ventricular assist system. The adapter comprises a shell, a circuit board and a cable assembly. The shell is provided with an accommodating cavity and two connecting ends positioned on the shell, and the two connecting ends can be connected with a connector; the circuit board is arranged in the accommodating cavity of the shell, the circuit board comprises two side plate bodies which are spaced from each other, and the two side plate bodies correspond to the two connecting ends respectively and can be electrically connected with the connectors connected to the connecting ends; the cable assembly is fixedly connected with the shell, the cable assembly comprises a connecting line, and the connecting line is electrically connected with the circuit board. The adapter has high signal transmission performance, the operation stability of the ventricular auxiliary system can be improved, and then the operation reliability of the ventricular auxiliary system is improved.

The invention provides an upgrading method and device for a ventricular assist device, and the method comprises the steps: writing an upgrading application program in a first memory into a second memory by a second kernel based on an upgrading command; the second kernel sends a first signal to the first kernel after writing is completed, the first signal is used for indicating that operation data of the motor is written into a third memory, and the third memory is a memory shared by the first kernel and the second kernel in the memory; and the second kernel reads the operation data from the third memory, controls the operation of the motor based on the upgrade application program, and sends a second signal to the first kernel, and the second signal is used for indicating to stop the control of the motor. According to the application, the first kernel and the second kernel are arranged in the controller, when the upgrading command is received, the upgrading application program is downloaded into the shared memory, and the operation of the motor is controlled through switching between the first kernel and the second kernel, so that software upgrading without stopping the motor can be realized, and harm to a user caused by stopping of the ventricular assist device is avoided.

The invention provides a flushing system control method and device and related equipment, and relates to the technical field of medical control. The method is applied to a ventricular assist device and comprises the steps that ventricular assist device parameters are obtained, and the ventricular assist device parameters represent the running state of the ventricular assist device; determining a target flushing flow according to the parameters of the ventricular assist device; according to the target flushing flow, a flushing system is controlled to complete flushing of the ventricular assist device catheter. The target flushing flow is determined by acquiring the parameters of the ventricular assist device, so that the flushing process is accurately controlled, thrombus formation is prevented, the reliability of the ventricular assist device is improved, the safety of a user is guaranteed, meanwhile, the long-term performance of the ventricular assist device is optimized, the maintenance frequency and cost caused by improper flushing are reduced, and the service life of the ventricular assist device is prolonged. And more stable and effective support is provided for users.

A method for providing a treatment recommendation to a physician for treating a patient is disclosed. The method comprises determining, from a processor in communication with a patient data repository, a first treatment recommendation based on a combination of selected patient demographics from the patient data repository applicable to the patient, and operational parameters of a plurality of ventricular assist devices (VADs) suitable for treating the patient, the first treatment recommendation having a first survival rate and comprising the use of a first VAD. The method then obtains a first signal from using the first VAD on the patient. The method then determines a second treatment recommendation based on the first signal and the first treatment recommendation, the second treatment recommendation having a second survival rate. The method then provides the second treatment recommendation to the physician if the second survival rate is higher than the first survival rate.

The invention relates to a ventricle connecting mechanism and a ventricle assisting system. The ventricle connecting mechanism comprises a suture ring, a clamping ring and a locking device, the suture ring is provided with a first through hole and a suture area surrounding the first through hole; the clamping ring comprises a ring body and a connecting end which are connected, the ring body is arranged on the suture ring, and the suture area is located on the periphery of the ring body. The locking device is connected to the connecting end part and can adjust the inner diameter of the ring body; the locking device can rotate relative to the connecting end part, so that the locking device can be switched between a horizontal state and an overturning state; in the horizontal state, the locking device is located on the periphery of the ring body and protrudes in the radial direction of the ring body. In the overturning state, one side, far away from the connecting end part, of the locking device is farther away from the sewing ring than in the flat placing state, so that the part, shielded by the locking device, of the sewing area is exposed. The locking device of the ventricle connecting mechanism can avoid a suturing area of a suturing ring, and uniform suturing of the suturing ring is facilitated.

A method is provided that includes inserting an inflow cannula of a left ventricular assist device (LVAD) of a LVAD system into a left chamber of a heart of a patient transeptally via a right atrium and a superior vena cava (SVC). An outflow cannula of the LVAD is coupled to a left subclavian artery or a left axillary artery. Other embodiments are also described.

The invention relates to a heart premature beat detection device and method, a ventricular assist system, a storage medium and equipment, and the detection device comprises a first sampling module which is configured to collect operation data of a drive motor in a ventricular assist device, and the operation data at least comprise rotation speed data; the calculation module is configured to determine a current rotating speed maximum value and a historical average maximum value according to the rotating speed data; the judgment module is configured to judge that premature beat occurs when the current rotating speed maximum value is larger than the gear rotating speed and smaller than the historical average maximum value. Compared with a traditional premature beat detection mode, premature beat detection can be carried out in real time in the operation process of the percutaneous ventricular auxiliary device, and traditional external monitoring equipment such as electrocardiogram or color Doppler ultrasound does not need to be relied on any more.

The invention features methods for the treatment of a cardiovascular disease using a polypeptide containing an extracellular ActRII variant, such as an ActRIIA variant, ActRIIB variant, or ActRII chimera. The polypeptide may include an extracellular ActRII variant fused to an Fc domain monomer. Treatment of a cardiovascular disease with a polypeptide described herein may reduce fibrosis, reduce inflammation, reduce cardiac remodeling, improve cardiac function, improve ventricular function, or slow or inhibit disease progression, which may reduce or delay the need for coronary revascularization, heart valve repair or replacement, implantation of a cardioverter-defibrillator, cardiac resynchronization therapy, a ventricular assist device, or a heart transplant.

The utility model relates to a catheter type ventricular assist system which can provide different flows and is small in trauma, and comprises a single-channel double-cavity cannula and a single-channel single-cavity cannula, the single-channel double-cavity cannula comprises an inner tube and an outer tube, the near end of the inner tube is communicated with an inlet tube of a blood pump, and an outlet tube of the blood pump is communicated with the near end of the outer tube or the near end of the single-channel single-cavity cannula. Blood is sucked in from the blood inflow port at the far end of the inner tube and flows out from the blood outflow port at the far end of the outer tube to form a small-flow circulation auxiliary system, and blood is sucked in from the blood inflow port at the far end of the inner tube and flows out from the opening at the far end of the single-channel single-cavity cannula to form a large-flow circulation auxiliary system. By means of the mode that the outer tube and the single-channel single-cavity cannula are switched, one set of ventricle auxiliary device can meet small-flow circulation assistance and large-flow circulation assistance, and the ventricle auxiliary device is suitable for different scenes. In small-flow circulation assistance, the outer tube and the inner tube are single-channel double-cavity intubation tubes, the single-channel double-cavity intubation tubes can be intervened to the designated position only through one incision, trauma is small, and postoperative recovery is fast.

A control method and control apparatus for a ventricular auxiliary apparatus and a ventricular auxiliary apparatus. The present invention pertains to the field of medical instruments. The ventricular auxiliary apparatus comprises a first component and is provided with a first control mode and a second control mode. The method comprises: acquiring a control operation for the first component, and controlling, in response to the control operation, the operation of the first component in a manner not restricted by constraints, wherein the constraints are constraints that apply when the first component operates in the second control mode. In the second control mode, the operation of the first component is restricted by the constraints, while in the first control mode, the operation of the first component is not restricted by the constraints. Compared to the second control mode, the first control mode masks the restriction of the operation parameters of the first component by the constraints, so that the degree of freedom of controlling the first component is improved, facilitating the adjustment and testing of the operation of the first component.