Closed-loop transcranial stimulation system and method

Abstract

The invention provides a closed-loop transcranial brain stimulation system and method. The system comprises a transcranial ultrasonic signal generation module, a transcranial ultrasonic stimulation module, an electroencephalogram and electromyogram signal acquisition and processing module and an electrode module; the electrode module is used for collecting brain muscle signals of an experimental subject; the electroencephalogram and electromyographic signal collecting and processing module is configured to be used for collecting signals of the electrode module, processing the signals and then sending detection signals to the transcranial ultrasonic signal generating module; the transcranial ultrasonic signal generation module is configured to receive the detection signal, generate a stimulation signal according to the detection signal and an adjustment strategy, and send the stimulation signal to the transcranial ultrasonic stimulation module; the transcranial ultrasonic stimulation module is configured to emit ultrasonic stimulation to the experimental subject according to the stimulation signal. The beneficial effects of the invention are that the transcranial ultrasonic signal generation module adjusts the signal parameters of the transcranial ultrasonic stimulation module to the experimental subject next time according to the brain and muscle signals collected by the electrode module and a system expected value through a configuration strategy, thereby achieving the closed-loop control of the transcranial brain stimulation.

Description

technical field [0001] The present disclosure relates to the technical field of transcranial ultrasonic stimulation, in particular to a closed-loop transcranial brain stimulation system and method. Background technique [0002] In recent years, with the rapid development of electronic technology, the development of electrical stimulator products is also very rapid. These electrical stimulators have gone through the early stage of discrete device manufacturing, and are now implanted and miniaturized, and have made great progress in terms of size and function. Commonly used are stimulators for clinical heart or brain, such as special stimulators such as cardiac pacemakers and brain pacemakers, and general-purpose stimulators commonly used in scientific research. Although some electrical stimulators have entered the stage of clinical application and have achieved good therapeutic effects, there are still some problems in some special application fields: the current general ele...

AI Technical Summary

Problems solved by technology

Although some electrical stimulators have entered the stage of clinical application and have achieved good therapeutic effects, there are still some problems in some special application fields: the current general electrical stimulators generally cannot automatically activate the physiological function according to changes in physiological signals. Generate stimulation, mainly through the preset stimulation mode, and send out stimulation signals at artificially specified moments

However, all TUS methods deliver brain stimulation in an open-loop mode that delivers stimulation signals at artificially prescribed times and cannot automatically generate stimulation based on changes in brain tissue physiological signals

This open-loop method does not have the characteristics of real-time processing, it belongs to the category of offline analysis

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