Vacuum negative pressure ultrasonic transdermal drug delivery device

Abstract

A vacuum negative pressure ultrasonic transdermal drug delivery device is composed of a negative pressure unit for generating dermal negative pressure suction and an air pumping bag for generating negative pressure in the negative pressure unit. The air pumping bag and the negative pressure unit are in fixed connection through a thread. The top of the air pumping bag is provided with an air pumping check valve and a valve fixing tube for fixing the air pumping check valve. An ultrasound unit acting on the human body is arranged in the negative pressure unit. The vacuum negative pressure ultrasonic transdermal drug delivery device has the advantages of being tight in drug delivery space, achieving the effects of dermal looseness, intradermal congestion, epidermis stratum corneum fracture, keratinocyte gap increasing and obvious skin resistance decreasing through the action of negative pressure and providing transdermal drug delivery power for a drug under the ultrasonic stimulation, thereby improving the transdermal efficiency of the drug, increasing the transdermal penetration amount of the drug and enhancing the therapeutic effect accordingly.

Description

technical field [0001] The invention is designed in the field of ultrasonic therapy, in particular to a vacuum negative pressure ultrasonic transdermal drug delivery device. Background technique [0002] Transdermal drug delivery is a new way of non-invasive drug delivery. After the drug penetrates the skin through the method of transdermal drug delivery, it enters the circulatory system and plays a therapeutic role. Transdermal drug delivery has the unique advantage of surpassing general drug delivery. It can avoid the “first-pass effect” of the liver and the destruction of the gastrointestinal tract, and avoid the damage to the gastrointestinal tract of oral drugs, especially those with high toxicity or irritation. At the same time, it also avoids the decomposition and destruction of the active ingredients of the medicine, has little side effects, and is an effective way to treat diseases. However, the skin is the natural barrier of the human body, with a very meticulous ...

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to provide a vacuum negative pressure ultrasonic transdermal drug delivery device, which allows the drug to safely and effectively penetrate the skin, adipose tissue and muscle tissue, so as to overcome the disadvantages of the single introduction method in the prior art. question

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