33results about How to "High transdermal efficiency" patented technology

The invention discloses a lidocaine hydrochloride transdermal ointment, comprising a lidocaine hydrochloride paste agent and a transdermal enhancer, wherein the transdermal enhancer consists of mango butter and menthol. Because of the synergism of the mango butter and menthol, the lidocaine hydrochloride has high transdermal efficiency reaching 17.09%, good skin softening property and high oxidation resistance, functions of softening skin, smoothing, moisturizing and protecting skin and low price.

A transdermal penetration-enhancing composition for improving the transdermal absorption effect of timolol, which is composed of white petrolatum and waxes, wherein the amount of white petrolatum is 65wt%-98wt%, and the amount of waxes is 2wt% ~35wt%. The transdermal penetration enhancer composition of the present invention can achieve about 92.61 μg cm within 8 hours without additional use of other conventional transdermal penetration enhancers. ‑2 The cumulative penetration of timolol has a significant effect of promoting transdermal absorption, low irritation to the skin, and higher safety.

The invention relates to a cell infiltration enhancing peptide, a composition comprising the cell infiltration enhancing peptide and combination thereof, peptide factors and optional ATP and application of the composition in cosmetics or skin care products. The invention further relates to a preparation method of the composition. The cell infiltration enhancing peptide and the combination thereofcan effectively enhance a transdermal effect of the peptide factors and other active large molecules, and then beauty and skin care effects of the peptide and the combination thereof can be better achieved.

The invention provides a medicinal patch for treating cough and asthma and a preparation method thereof. The medicinal patch comprises a TPU film coated with a pressure-sensitive adhesive, a Pe film, a medicinal preparation and a release film, wherein the medicinal preparation is prepared from extract, gel, borneol, Span 60 and propylene glycol; the extract is prepared from bulbus fritillariae cirrhosae, semen armeniacae amarae, platycodon grandiflorum, rhizoma zingiberis and liquorice; and the gel is prepared from xanthan gum and konjac powder. The method for preparing the medicinal patch for treating cough and asthma comprises the steps: preparing the extract, preparing the gel, preparing the medicinal preparation and finally preparing the medicinal patch. According to the medicinal patch prepared by the invention, the gel serves as a drug carrier, the active ingredients easily efficiently permeate into skin to exert the drug effects under the effect of the borneol penetration enhancer, and the medicinal patch has the advantages of low sensitization, small skin irritation, good skin adhesion and difficulty to drop.

The invention provides a preparation method of crocodile nail effective components, which belongs to the technical field of biology and comprises the following steps: providing slurry containing water and powdery crocodile nails; performing high-voltage pulse on the slurry to obtain effective components; and recovering the effective components; wherein the effective components contain polysaccharide and protein components; a pharmaceutical composition comprising sophocarpidine alkaloids, crocodile armor effective component and a transfer medium is also prepared. The crocodile armor effective component preparation method provided by the invention can increase slurry fluidity, prevent local high temperature in an electric field from destroying substance activity, and promote transdermal absorption efficiency of effective components; the crocodile armor effective component can be used for preparing a medicinal composition containing the crocodile armor effective component, and also comprises an application of the effective component or the medicinal composition in preparing an antioxidant or anti-hepatic fibrosis medicine.

The invention relates to the technical field of skin care products, in particular to an inclusion essence capable of instantly brightening skin tone and a preparation method thereof. The essence includes the following raw materials in parts by weight: 15-20 parts of microcrystalline cellulose, 0.1-0.1 parts of coenzyme Q10 6.0 parts, protein-phospholipid 10-15 parts, protein silk peptide 0.01-1.5 parts, carbomer resin 1.0-1.5 parts, yeast extract 0.01-2.0 parts, rose essential oil 5-10 parts, hydroxypropyl methylcellulose 0.1-1.0 parts, whitening agent 0.01-3.0 parts, moisturizing agent 8-18 parts, antioxidant 2-7 parts. The essence of the present invention has strong biocompatibility and no damage to the skin. The fat-soluble active substance is made into lipid inclusion matrix by using nano-encapsulation technology, which can effectively improve the stability and biological activity of the active substance, and promote the production of the active substance. The transdermal efficiency can also effectively reduce the irritation of active substances, improve the bioavailability of them by the human body, and at the same time effectively inhibit the activity of tyrosinase, prevent the generation of pigmentation, and repair epidermal cells to achieve the effect of whitening and moisturizing , making the skin bright and moist.

The invention provides a plant ethosome hair loss preventing pilatory and a preparation method and a using method thereof. The plant ethosome hair loss preventing pilatory comprises a plant ethosome, a plant penetrating agent and other adjuvant materials. According to the plant ethosome hair loss preventing pilatory and the preparation method and the using method thereof, a plant extract which is effective to hair growth is made to be the ethosome, because a vesicle structure formed by the ethosome has better flexibility and film fluidity, effective components can be carried to directly penetrate through a cuticle, and the transdermal efficiency is obviously improved; and meanwhile the plant penetrating agent is added, plant molecules which are not completely packaged are helped to penetrate into follicle cells to develop the effect of the plant molecules to promote hair to grow, and the hair loss preventing and hair growing effects are good.