123 results about "Laser lithotripsy" patented technology

The embodiment of the invention provides an endoscope laser lithotripsy system, a control method of the endoscope laser lithotripsy system and an endoscope imaging catheter. The method comprises the steps that a perfusion pump is controlled to perfuse liquid into a target area, and a suction pump is controlled to suck the liquid in the target area; at least any one of the following parameters is acquired: an image in the target area is acquired through an imaging device, the temperature in the target area is acquired through a detection unit, and the pressure in the target area is acquired through the detection unit; when the laser outputs laser to the target area through the optical fiber, the control unit controls the perfusion pump, the suction pump and the laser according to the collected parameters. Linkage control over the flow speed of perfusion liquid, the flow speed of suction liquid and laser output of the laser device can be achieved, and safety and effectiveness of lithotripsy operation can be improved.

Laser lithotripsy systems and methods with a controlled retropulsion setting to facilitate manipulation, migration, and ablation of a calculi structure are disclosed. An endoscopic lithotripsy system comprises a laser system to provide laser pulses to a calculi structure in an anatomical environment, and a controller circuit to localize the calculi structure. If it is determined that the calculi structure is not at a target location, the laser system emits first laser pulses according to a first laser output setting, which produces a high retropulsion effect to mobilize and reposition the calculi structure to the target location. For calculi structure located at or migrating to the target location, the laser system emits second laser pulses according to a second laser output setting, which produces a lower retropulsion effect than the first laser pulses, but a higher efficiency to ablate or fragment the calculi structure.

The invention belongs to the technical field of hepatobiliary calculus treatment, and discloses a hepatobiliary calculus negative pressure suction and laser lithotripsy integrated device which comprises a wrapping mechanism, and the wrapping mechanism comprises an abutting plate, a buffer pad, a connecting ring, a shell, a first cavity, a first vent groove, an air conveying pipe and a wrapping air bag; through cooperation of the wrapping air bag, the protective air bags and other structures, the calculus can be conveniently wrapped, the calculus is wrapped through the multiple protective air bags, an isolation layer is formed, the calculus is isolated from surrounding important tissues such as bile duct walls and blood vessels, and the calculus is prevented from being damaged. In the lithotripsy process, both energy generated by laser and splashing of stone fragments are limited in the protective air bag, damage to surrounding tissue is effectively prevented, meanwhile, the stone fragments can be prevented from being diffused to the surrounding tissue in the lithotripsy process, and complications such as bile duct blockage and inflammation are avoided. And subsequent negative-pressure suction operation is facilitated to thoroughly remove the dust.

According to the anti-blocking adsorption laser operation endoscope and the method, the anti-blocking adsorption laser operation endoscope is installed at the position far away from an endoscope body and an adsorption opening through an adsorption switch, or the adsorption opening is a plane or a curved surface and comprises a structure of at least two open holes and matched size design. Or an ultrasonic device and an installation mode of the ultrasonic device are adopted, so that the probability that the broken stones block the suction channel is greatly reduced, and blockage is prevented, and meanwhile, the stones are continuously reset at the position of the suction port through a method that the suction switch repeatedly and continuously connects and disconnects the suction port and the suction source; therefore, the continuous laser lithotripsy performance during the operation is kept; through the program control of the suction switch of the anti-blocking adsorption laser operation endoscope, the working intensity of an operation doctor during the operation for controlling an instrument is reduced, so that the operation is more convenient and simpler; through the design of the quick-connection type connector of the anti-blocking broken stone adsorption laser operation endoscope component, instrument sterilization is more convenient, function expansion is more flexible, or independent production is arranged; the invention relates to a method for treating human and animal focuses, especially calculi, by using an anti-clogging laser surgery endoscope catheter.

The invention discloses a multi-mode feedback control method and system for a femtosecond laser stone crusher, and relates to the technical field of medical instruments. The method comprises the following steps: constructing spectral component analysis, collecting spectral signals, and executing target chemical component identification; ultrasonic position detection: acquiring an ultrasonic echo signal through a transducer, and calculating a spatial distance; performing vision-assisted positioning, acquiring image data through an endoscope, and generating space image information; according to the spectrum identification result, the distance parameter and the space image information, multi-source data synchronization processing is completed; generating a laser parameter control instruction according to the fusion result; and executing a real-time feedback regulation and control process, obtaining feedback information, and completing control parameter updating and closed-loop response. Through fusion of multi-modal information such as spectrum identification, ultrasonic distance measurement and visual navigation, real-time identification of stone types, intelligent matching of laser parameters and accurate control of spatial positioning are realized, and the accuracy, safety and intuition of lithotripsy operation are remarkably improved.

The invention discloses an intelligent control system for pulse thulium laser lithotripsy treatment, and belongs to the field of medical instruments. According to the system, through intelligent parameter matching and dynamic regulation and control, the problem that traditional laser lithotripsy treatment parameters are complex in adaptation is solved. The system comprises a calculus feature input module used for receiving a calculus position, a CT value and a surgical instrument type; the processor module is used for generating recommended laser energy parameters based on a preset logic rule; the laser energy output unit supports a pedal switch to switch a lithotripsy mode and dynamically adjust output; the self-adaptive perfusion flushing unit is used for matching flow velocity according to energy parameters and stone characteristics to ensure temperature rise safety; and the data acquisition and updating module is used for collecting clinical data through the Internet of Things and optimizing recommendation parameters based on big data. The method has the advantages that parameter optimization of personalized parameter recommendation, dynamic flow rate control and data driving is achieved, and the lithotripsy efficiency, safety and the treatment effect are remarkably improved.

The Integrated Laser Basket (ILB)—a medical device used for treating various types of stone deposits, including, but not limited to, kidney stones, gallstones, bladder stones, prostate stones, pancreatic stones, or any combination thereof, in human or animal patients. The ILB merges the benefits of laser lithotripsy and stone retrieval in a single device, offering a more comprehensive and minimally invasive approach to stone management. Example methods of using the ILB to treat various types of stone deposits in human and non-human patients are also described.

The present invention provides a laser system for treating calculi in a human or animal body, comprising: a diode-pumped laser configured to emit radiation in a wavelength range between 1.81 and 2.2 microns; and a driver configured to provide modulated current to the diode-pumped laser and coupled to a controller configured to output a control signal such that the diode-pumped laser emits a sequence of laser pulses, a shape of each laser pulse is formed with: a first sub-pulse and a second sub-pulse spaced temporarily from one another; an energy of the first sub-pulse varying in a range of 0.02 to 0.15 J; a peak power of the first sub-pulse varying in a range of 50 to 500 W; an interval between the first sub-pulse and the second sub-pulse varying in a range of 50 to 900 µs; an energy of the second sub-pulse exceeding the energy of the first sub-pulse and varying in a range of 0.1 to 10 J; a peak power of the second sub-pulse exceeding the peak power of the first sub-pulse and varying in a range of 300 to 20000 W.

Devices, systems, and methods for a retrieval device for addressing a kidney stone. A retrieval device includes an expandable basket with a deployed cover. The basket is expanded and maneuvered around the kidney stone. The cover is then deployed around the basket to contain the kidney stone for laser lithotripsy. Fragments at or below a target size are allowed to escape through apertures in the cover or are removed via a suction tube.

A surgical laser fiber for use in surgical laser procedures such as laser lithotripsy includes a relatively small diameter silica core surrounded by a thin intermediate doped silica cladding and a relatively thick outer glass cladding or ferrule surrounding the thin intermediate doped silica cladding, with the result that erosion of the fiber is primarily confined to the silica core, causing the relatively thick outer glass cladding or ferrule to form a standoff that extends beyond the eroded end of the silica core as lasing proceeds. The diameter of the silica core may be approximately 80 μm and a thickness of the outer glass cladding may be approximately 200 μm. The surgical laser fiber may be used with Thulium Fiber Lasers, or may be adapted for use with both Thulium Fiber Lasers and Holmium YAG lasers.

The invention relates to the technical field of bladder stone surgery auxiliary tools, in particular to a bladder lithotripsy surgery auxiliary operation device which comprises a flushing fluid bubble increasing device and a flushing pipe assembly. The flushing pipe assembly comprises a flushing liquid inlet pipe, and a liquid inlet of the flushing liquid inlet pipe is communicated with the gas-liquid outlet; the flushing pipe assembly further comprises an outer sheath catheter, and a negative pressure liquid extraction opening is formed in the outer side end of the outer sheath catheter. By the adoption of the device, gas-liquid mixed flushing liquid containing a large number of bubbles can be obtained, in the laser lithotripsy process, liquid inlet flushing is carried out, meanwhile, the flushing liquid can be synchronously pumped out of an operation cavity through negative pressure, calculus particles are pumped out of the operation cavity in time, and the operation effect can be greatly improved.

The utility model belongs to the technical field of laser lithotripsy, and discloses an in-vitro laser lithotripsy efficiency detection device. The device comprises a container, a liquid injection mechanism and a collector, the container is provided with a first opening and a second opening, the first opening is used for inserting a laser fiber, the second opening is located at the bottom of the container, the liquid injection mechanism is communicated with the container and can inject liquid into the container, and the collector is provided with a third opening and at least one fourth opening. The third opening is formed in the top of the collector, the fourth opening is formed in the bottom of the collector, the third opening is communicated with the fourth opening, the second opening is communicated with the third opening, and the size of the fourth opening is not larger than that of the second opening. By means of the device, in-vivo lithotripsy conditions can be simulated, so that detection is closer to clinical practical operation, particles obtained after lithotripsy can be distinguished according to the size, the lithotripsy effect of laser lithotripsy is evaluated, and parameter setting of clinical practical operation can be guided easily.

An intraluminal device for delivering pressure waves includes a flexible elongate member configured for positioning within a body lumen. The flexible elongate member includes: an outer sheath with a sealed distal end, a reaction chamber, and a sealed acoustic window. The flexible elongate member also includes an optical fiber configured to be coupled to a light source and translated longitudinally within the outer sheath. When the reaction chamber is filled with a photoreactive fluid, a beam of light emitted by the optical fiber causes the photoreactive fluid to generate a set of pressure waves that is delivered to a location of the body lumen via the sealed acoustic window. The sealed acoustic window and the sealed distal end prevent the photoreactive fluid from entering the body lumen.

The invention discloses a hollow-core anti-resonance optical fiber design method and system for a femtosecond laser stone crusher, and relates to the technical field of medical laser instruments. The method comprises the steps that an anti-resonance transmission unit is constructed, the anti-resonance transmission unit is composed of an air core and anti-resonance quartz cladding tubes periodically arranged on the periphery, the cladding tubes form an anti-resonance transmission band gap with a specific wavelength through precisely designed wall thickness and spacing, and the air core serves as a main transmission channel; a water-cooling temperature control unit is integrated, the water-cooling temperature control unit comprises a spiral or snakelike micro-channel structure integrated in an outer cladding of the anti-resonance transmission unit, the outer cladding is made of a biocompatible high polymer material, a micro-channel and an optical fiber are axially arranged at a preset angle, and a forced convection heat dissipation path is formed by injecting a cooling medium. By optimizing the anti-resonance transmission unit and the water-cooling temperature control unit, stable laser transmission, efficient thermal management and reliability under long-time high-power laser operation are realized.

A laser lithotripsy system may include a light energy source and a catheter. The catheter may comprise an optical fiber comprising a core and a cladding that encases the core. The optical fiber may be configured to be optically coupled to receive laser light from the light energy source. The optical fiber may include at least one evanescent portion and at least one non-evanescent portion. When light propagates through the core, an evanescent field may be transmitted out of the optical fiber in the evanescent portion and may not transmitted out of the optical fiber in the non-evanescent portion.

Provided is an output adjustment device for a laser lithotripsy apparatus including: a processor including hardware, the processor being configured to: pulse a laser beam; adjust an output of the pulsed laser beam; monotonically increase the output of the laser beam as a first period to generate a bubble binding body containing a plurality of bubbles from a laser emission end; monotonically decrease the output of the laser beam with a gradient larger than a predetermined gradient as a second period following the first period to cause the bubble binding body to disappear so that a crushing target is attracted to the laser emission end; and before the bubble binding body is generated, raise a liquid temperature in a region where the bubble binding body is generated by generating the bubbles and causing the bubbles to disappear.

According to the anti-blocking lithotripsy laser catheter and the method, the anti-blocking lithotripsy laser catheter is installed at the position away from the lithotripsy catheter and an adsorption opening through an attraction switch, or the adsorption opening comprises at least two open holes, and the structural design and the size of the adsorption opening face are matched, or an ultrasonic device and an installation mode thereof are adopted. The probability that the broken stones block the suction channel is greatly reduced, meanwhile, the positions of the stones at the adsorption opening are continuously reset through the method that the adsorption opening and the suction source are repeatedly and continuously connected and disconnected through the suction switch, and therefore the continuous laser lithotripsy performance in the operation is kept. By means of program control of the anti-blocking lithotripsy laser catheter suction switch and the design of the endoscope fixator, the working intensity of an operation doctor during an operation when the operation doctor manipulates an instrument is reduced, and operation is more convenient and simpler; through the design of the quick-connection type connector of the anti-blocking lithotripsy laser guide pipe component, instrument sterilization is more convenient, and independent production is convenient to arrange; the invention relates to a method for treating human and animal calculi by using an anti-blocking lithotripsy laser catheter.

Steering handles with manifolds that enable an operator to configure an endoscopic system in situ for a variety of tasks, including irrigation, aspiration, or both. In addition, the disclosed endoscopic systems facilitate rapid reconfiguration of the location of a laser fiber optic within a catheter assembly. The laser fiber optic, for example, can be removed from an irrigation channel of the endoscopic system and reinserted in the aspiration channel during a laser lithotripsy procedure. In some embodiments, the removal and reinsertion can be performed in situ, without removing the catheter from the patient or the treated organ. These aspects of the disclosed system reduce the time required to perform laser lithotripsy procedures, with less trauma to the patient.

To monitor conditions of media proximate to an endoscopic treatment or diagnostic site in real time.SOLUTION: Disclosed herein are systems and methods for monitoring a condition associated with a medium proximate to a target region. The system comprises a surgical laser, and a surgical fiber coupled to the surgical laser for delivering laser light to a target region and receiving at least a portion of the laser light reflected from the target region. The system further comprises a processor configured to analyze the collected reflected laser light and determine, based at least in part on the analysis of the reflected laser light, a value of a parameter associated with the medium proximate to the target region.SELECTED DRAWING: Figure 5

The invention belongs to the technical field of urinary devices, and particularly relates to a urinary calculus breaking and removing device based on intelligent positioning and an operation method.The urinary calculus breaking and removing device comprises a thick tube part, a thin tube part arranged at the front end of the thick tube part and a probe part arranged at the front end of the thin tube part; the lithotripsy mechanism is composed of a laser lithotripsy probe and an electric control module, and the operation end of the electric control module penetrates through the thin pipe part and extends into the thick pipe part; by arranging the intelligent positioning and tracking unit, the endoscope camera shooting recognition module, the miniature ultrasonic probe and the posture sensing module, the problems that a traditional operation is large in positioning error and has a view blind area are solved, the calculus positioning accuracy is greatly improved, the ureter mucosa injury risk caused by positioning deviation is reduced, and the operation safety is improved. A double-calculus-removing structure composed of the clamping jaw mechanism and the negative-pressure adsorption assembly is arranged, calculus removing, namely calculus removing, is achieved through cooperation of the clamping jaw mechanism and the negative-pressure adsorption assembly, the pain point that fragments are prone to remaining in a traditional operation is solved, and secondary operation is not needed.

The application discloses a urinary calculus crushing parameter optimization method and system based on multi-modal pathological feature fusion, relates to the technical field of health information science, and extracts a preoperative feature vector F of a patient before operation, and calculates a theoretical fragmentation energy efficiency I according to the preoperative feature vector F, so as to generate an initial laser lithotripsy parameter P, thereby improving the initial accuracy and scientificity of treatment. In the operation, the original signal data set DSA is generated by collecting acoustic signals through a miniature hydrophone, and the pulse fragmentation efficiency η at the time t is calculated t , and the pulse fragmentation efficiency sequence SSEQ is constructed, the objective and real-time quantification of the lithotripsy effect is realized, and the limitation of visual observation is overcome. Finally, the state evaluation result is generated by comparison, and the laser lithotripsy parameter optimization strategy is executed, adaptive regulation is constituted, and the efficiency and safety of the whole operation are ensured.

Steering handles with manifolds that enable an operator to configure an endoscopic system in situ for a variety of tasks, including irrigation, aspiration, or both. In addition, the disclosed endoscopic systems facilitate rapid reconfiguration of the location of a laser fiber optic within a catheter assembly. The laser fiber optic, for example, can be removed from an irrigation channel of the endoscopic system and reinserted in the aspiration channel during a laser lithotripsy procedure. In some embodiments, the removal and reinsertion can be performed in situ, without removing the catheter from the patient or the treated organ. These aspects of the disclosed system reduce the time required to perform laser lithotripsy procedures, with less trauma to the patient.

Disclosed are a device and a method of autonomous stone ablation during laser lithotripsy, the method including inserting a catheter into a lumen; navigating the catheter through the lumen along an insertion trajectory; obtaining at least one image of an object within the lumen; segmenting the at least one image; determining a size of the object; and in response to the size exceeding or being equal to a predetermined size: defining a region of lasing of the object, aligning a tip of the catheter with the region of lasing, and performing lithotripsy.

A system for monitoring temperature when carrying out laser light-based lithotripsy in which includes an endoscopic assembly comprising a working channel for a fiber optic cable which is optically coupled to a laser on a proximal side and include a light exit aperture on a distal side, and an irrigation fluid channel opening into a region of the light exit aperture on the distal side which is in fluid communication with an irrigation fluid reservoir on the proximal side. The system includes a modular unit including a flow sensor, which determines the irrigation flow rate without coming into contact with the irrigation fluid; input, via which operating parameters of the laser can be determined, can be transmitted to a processor connected to the input; a temperature sensor which determines the temperature of the irrigation fluid without coming into contact with the irrigation fluid; an analyzer, which numerically determines the temperature of the irrigation fluid and the determined applied laser power, and the temperature generated intracorporeally during the laser lithotripsy at the location of the light exit aperture, and a comparator, which produces a signal in the event that a threshold value is exceeded.

A laser lithotripsy system may include a light energy source and a catheter. The catheter may comprise an optical fiber comprising a core and a cladding that encases the core. The optical fiber may be configured to be optically coupled to receive laser light from the light energy source. The optical fiber may include at least one evanescent portion and at least one non-evanescent portion. When light propagates through the core, an evanescent field may be transmitted out of the optical fiber in the evanescent portion and may not transmitted out of the optical fiber in the non-evanescent portion.

Steering handles with manifolds that enable an operator to configure an endoscopic system in situ for a variety of tasks, including irrigation, aspiration, or both. In addition, the disclosed endoscopic systems facilitate rapid reconfiguration of the location of a laser fiber optic within a catheter assembly. The laser fiber optic, for example, can be removed from an irrigation channel of the endoscopic system and reinserted in the aspiration channel during a laser lithotripsy procedure. In some embodiments, the removal and reinsertion can be performed in situ, without removing the catheter from the patient or the treated organ. These aspects of the disclosed system reduce the time required to perform laser lithotripsy procedures, with less trauma to the patient.

The application relates to the technical field of target tracking, and in particular to a training method of a laser point detection model based on a deep neural network, a laser point detection method and system, and a laser lithotripsy system, which solves the technical problem that, when a laser point is detected in an endoscope image, false detection is caused by interference terms, and safety is reduced because the laser may be fired instantaneously due to misjudgment. The training method of the laser point detection model based on the deep neural network provided by the application adopts a decoupling structure, a classification branch network relies on central region texture, and a regression branch network relies on edge position information; the decoupling structure is used to process category probability prediction and boundary box coordinate regression respectively, information interaction between the two branches is performed simultaneously, the classification branch improves positioning precision with the aid of boundary information of the regression branch, the regression branch improves stability with the aid of central information of the classification branch, and therefore the prediction accuracy of the laser point is improved.

Systems and methods for performing laser lithotripsy include introducing a lithotripsy medium containing nanoparticles into a body cavity comprising target obstructions and applying laser energy through the lithotripsy medium to disrupt the target obstructions. The nanoparticles may have diameters configured to enhance absorption efficiency of the laser energy. The nanoparticles may include organic polymers such as PEDOT: PSS or inorganic compounds such as indium tin oxide. Systems may include a laser source, a fluid delivery component configured to deliver the nanoparticle-containing lithotripsy medium, and an optical fiber for delivering laser energy. Methods of manufacturing lithotripsy media include selecting target wavelengths, synthesizing nanoparticles with corresponding absorption characteristics, and dispersing the nanoparticles at selected concentrations.

The present disclosure provides an endoscopic laser lithotripsy device and a method for such a device, wherein image acquisition, laser emission, illumination and / or image processing are configured to mitigate distortion in captured images caused by the laser.

The utility model discloses a laser optical fiber lithotripsy efficiency detection device which comprises a first container, a supporting device, a filter screen, an optical fiber driving device and an optical fiber clamping device. The supporting device is arranged in the first container, and the filter screen is arranged on the supporting device. The moving end of the optical fiber driving device is located above the filter screen and can move in the X direction, the Y direction and the Z direction. And the optical fiber clamping device is arranged at the moving end of the optical fiber driving device. During working, stones are placed on the filter screen, and normal saline is added into the first container until the stones are immersed. The optical fiber driving device drives the optical fiber to move to complete laser lithotripsy. And calculating the time of the whole stone crushing process after all stones above the filter screen are crushed and fall below the filter screen. And finally, an experimenter can calculate the lithotripsy efficiency of the laser optical fiber according to the size of the calculus, the mesh size and the lithotripsy time.