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Method and apparatus for laser lithotripsy

A laser, laser system technology, used in radiation therapy, parts of surgical instruments, treatment, etc.

Inactive Publication Date: 2011-12-14
拜欧利泰克医药销售公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, an important drawback of this laser is that the energy produced has an equally powerful effect on stones and soft tissue
Also, size and cost are important issues to consider

Method used

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  • Method and apparatus for laser lithotripsy
  • Method and apparatus for laser lithotripsy
  • Method and apparatus for laser lithotripsy

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Experimental program
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Effect test

Embodiment 1

[0045] A 1470 nm diode laser source with 400 μm fibers was used for lithotripsy of calcium oxalate, uric acid and cystine urinary stones. Pulsed radiation of high peak power is used to achieve the conversion of focused high-intensity energy into mechanical energy in the form of cavitation bubbles associated with the emergence of shock waves. This mechanical energy is suitable for breaking up the stones. Good lithotripsy was achieved with a power of 20W and a pulse consisting of turning the power on for 1.0 seconds and turning the power off for 0.3 seconds.

[0046] Table I shows the results of in vitro experiments using a 1470 nm diode laser. For different types of fibers, the power threshold for achieving plasma formation was determined at the fiber tip.

[0047] fiber

[0048] Table I. Power Thresholds for Plasma Formation

Embodiment 2

[0050] Wavelengths of 1470nm and 1940nm are highly absorbed in water; these radiations generate high-energy bubbles at the fiber tip with photothermal and cavitation effects. Accordingly, in vitro tests were carried out using a diode source emitting a wavelength combination of 1470nm and 1940nm and with the fiber tip immersed in water under continuous wave irradiation in order to try to achieve urolith comminution. Photothermal bubbles called "non-sparking or non-sparking plasma bubbles" were created at the fiber tips, which were able to destroy urinary stones and also ablate soft tissues in endocavity urology. Stones are destroyed without significant heat gain in the surrounding water. Complete destruction of medium-hard urinary stones and marked erosion of cystine stones were obtained.

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Abstract

A system and method for the destruction / ablation of stones, calculi or other hard substances by means of laser energy is disclosed. As a consequence, several important medical treatments can be performed, especially lithotripsy. The system comprises a diode laser source emitting at least at one wavelength, one or more optical fibers which convey laser radiation to the treatment site and a liquid delivery system used for creating a liquid environment around the stones (calculi). The laser device emits at least one wavelength which is highly absorbed in the surrounding / covering medium, thus causing evaporation and cavitation effects that lead to stone / calculi destruction. Different radiation configurations may be used. In one embodiment continuous radiation is used to create sparkler-less plasma bubbles able to destroy hard substances.; In another embodiment high peak power pulsed radiation is used. Wavelengths of 1470 nm, 1940 nm, or 1550 nm are preferred. Additionally it can be applied in combination with another wavelength with medium absorption in water such as 980 nm. In another embodiment a concentric double core fiber is used, in which the ignition radiation is guided in near single mode, inner core and the radiation used to maintain and enhance the pulse is guided into the surrounding second outer core. In another preferred embodiment, the use of multiple optical fibers allows for treating larger stones in a shorter time period. In another preferred embodiment, cooling liquid is supplied to the impact site to further reduce thermal heating of the stone, thus diminishing risks of tissue damage caused by stone fragment anchorage and thermal energy.; With these safer and improved methods and system, enhanced lithotripsy treatments can be performed in a shorter treatment time, destroying a wider range of stones with less risk of tissue damage, and less patient and physician stress.

Description

[0001] Domestic priority under 35USC 119(e). [0002] This patent application claims U.S. Provisional Patent Application Serial No. 61 / 119,190, filed December 2, 2008, by Leonardo Cecchetti, Walter Cecchetti, and Wolfgang Neuberger, entitled "Method and Device for Laser Lithotripsy," and additionally by Leonardo Cecchetti, Benefit and Priority of US Serial No. 12 / 628,634, "Method and Device for Laser Lithotripsy," filed December 1, 2009, by Walter Cecchetti, and Wolfgang Neuberger, all of which are incorporated herein by reference. technical field [0003] The present invention relates to minimally invasive devices and methods for use in laser therapy. More specifically, the present invention relates to lithotripsy based on laser radiation. Background technique [0004] Calculi, or stones, are the result of material, usually mineral salts, that form in internal organs or ducts. They can cause a variety of medical disorders through several mechanisms: [0005] -Irritates n...

Claims

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Application Information

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IPC IPC(8): A61B18/26A61B17/22A61B18/20A61N5/067A61B18/22A61B17/221
CPCA61B2018/263A61B2017/2215A61B2018/00029A61B18/26A61B18/24
Inventor L·切凯蒂W·切凯蒂W·纽博格
Owner 拜欧利泰克医药销售公司
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