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32results about How to "Significantly inhibit tumor" patented technology

Pistacia chinensis bunge and gingerol containing composition for chemotherapy for cancer with capabilities of decreasing toxicity and synergism

The invention discloses a pistacia chinensis bunge and gingerol containing composition for chemotherapy for cancer with the capabilities of decreasing toxicity and synergism and belongs to the technical field of medicaments. The pistacia chinensis bunge and gingerol containing composition is prepared from the following components including a pistacia chinensis bunge extract and a gingerol component with the weight ratio of (10-25):(1-3), and the following medicinal raw materials including pachyma cocos, fructus amomi, fructus evodiae, cuscuta, all-grasses of desertliving cistanche, pinellia ternate, perilla, dried tangerine peels, trogopterus dung and blackberrylily rhizome can also be added. According to the pistacia chinensis bunge and gingerol containing composition, with the pistacia chinensis bunge extract and the gingerol component as the core raw materials, the natural medicament composition is prepared with matching of other auxiliary components; residues in the extraction process of gingerol are kept for replacing a part of the auxiliary components, can serve as both the auxiliary component and the effective component, are capable of effectively inhibiting emesis caused by chemotherapy for the cancer and have the actions of synergism and decreasing toxicity for treatment of the cancer; after adding the traditional Chinese medicine components, the traditional Chinese medicine components take synergistic effect to the pistacia chinensis bunge extract and the gingerol, have the action of preventing and treating the emesis caused by the chemotherapy for the cancer, also have certain therapeutic effect for the cancer and are capable of inhibiting tumors.
Owner:SHANDONG PROVINCIAL HOSPITAL

The use of the extract of Pachyphylla alkaloids for the preparation of drugs for inhibiting emt-6 breast cancer cells

The invention discloses a paris polyphylla alkaloid extract with an anti-tumor effect and a preparation method and application thereof, and solves the technical problem that in the prior art, a preparation and utilization method of a paris polyphylla alkaloid component is not provided. The paris polyphylla alkaloid extract is prepared by extracting paris polyphylla with an acidic solution, then alkalizing, precipitating, dissolving precipitate, applying the dissolved precipitate to macroporous resin, and eluting with alcohol. The preparation method of the paris polyphylla alkaloid extract comprises the following steps: adding the paris polyphylla into the acidic aqueous solution, soaking, heating, extracting, filtering, adjusting the pH value of a filtrate till an alkaline state, centrifuging and collecting the precipitate; adding the precipitate into ethanol, dissolving the precipitate, and applying the dissolved precipitate to the macroporous adsorption resin for adsorption, then sequentially eluting the macroporous adsorption resin column with water, a 30% aqueous ethanol solution, a 50% ethanol solution and a 70% aqueous ethanol solution, and collecting an eluate obtained by using 70% ethanol; and concentrating, and drying at low temperature to obtain the paris polyphylla alkaloid extract. The invention further discloses application of the paris polyphylla alkaloid extract to preparation of anti-tumor medicines. The preparation method is simple and convenient in process and easy and convenient to operate; and the obtained paris polyphylla alkaloid extract has an exact anti-tumor effect.
Owner:HEBEI RUILONG BIOTECHNOLOGY CO LTD
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