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Composition of dried ginger and evodia rutaecarpa, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer

A technology of dried ginger cornel and composition, which is applied to the combination of dried ginger and Evodia, its preparation and its use in the preparation of drugs for reducing toxicity and enhancing efficacy in cancer radiotherapy and chemotherapy, so as to inhibit tumor, reduce vomiting rate, Increased inhibitory effect

Inactive Publication Date: 2012-05-23
QINGDAO UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no Chinese patent medicine that can reduce the side effect of vomiting and enhance the effect of anti-cancer radiotherapy and chemotherapy

Method used

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  • Composition of dried ginger and evodia rutaecarpa, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer
  • Composition of dried ginger and evodia rutaecarpa, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer
  • Composition of dried ginger and evodia rutaecarpa, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer

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Experimental program
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Effect test

Embodiment approach

[0042] (1) Preparation of concentrated extract of dried ginger and cornus officinalis decoction

[0043] According to the compatibility ratio of 1:1, take dried ginger and Evodia rutaecarpa, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, add 6 times the amount of distilled water to the dregs, and Soak, decoct, and filter, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a yellow powder, which is the concentrated extract of dried ginger and cornel decoction.

[0044] (2) preparation of gingerol

[0045] Cut the dried ginger into thin slices, dry it naturally, grind it into powder with a high-speed universal grinder, pass through a 30-mesh sieve, put the sifted fine powder into a 5000mL large grinding bottle, and soak...

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Abstract

The invention relates to a natural pharmaceutical composition, a preparation method thereof and an application thereof in preparing an attenuating synergistic medicament in radiotherapy and chemotherapy of cancer. The natural pharmaceutical composition is composed of concentrated extract of decoctions of dried ginger and evodia rutaecarpa, gingerol, evodia rutaecarpa extract and evodiamine in proportion of (1-4):(3-7):(2-9):(2-3). The composition provided by the invention has good curative effects on vomit and the like caused by the side effects of radiotherapy and chemotherapy of cancer, andalso plays an effect on inhibiting tumor.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition which is composed of dry ginger decoction concentrated extract, gingerol, Evodia rutaecarpa extract and evodiamine, the preparation of the natural medicine composition The method and the use of the natural medicine composition in preparing medicines for reducing side effects of vomiting caused by cancer radiotherapy and chemotherapy and synergizing cancer treatment. Background technique [0002] Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive radiotherapy and chemotherapy. Although there is a certain curative effect, most patients will experience side effects to varying degrees after radiotherapy and chemotherapy. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P35/00A61K9/48A61K31/519A61K36/9068A61P1/08A61P39/02A61K9/20
Inventor 石振艳岳旺刘小红倪倍倍
Owner QINGDAO UNIV
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