80 results about "Cancer Radiotherapy" patented technology

The invention relates to a preparation method of chronic wound dressing, and in particular, relates to a medical dressing loaded with nano silver and bioactive factors and a preparation method thereof. The dressing includes calcium alginate, chitosan or a chitosan derivative as a matrix and is loaded with nano silver antibacterial composition particles and a growth factor EGF. During preparation,calcium alginate core microspheres wrapped with the growth factor are obtained by dropwise adding a sodium alginate solution mixed with the growth factor into a calcium chloride solution. The microspheres are added to a chitosan acetic acid solution to form a polyelectrolyte complex. Then the polyelectrolyte complex is mixed and stirred with nano silver and chitosan, the mixture is added to sodiumalginate, crosslinking and freeze-drying are performed, and finally, the chronic wound dressing loaded with nano silver and the growth factor is formed. The raw materials of the method are cheap andeasy to obtain, the preparation process is stable, the bacteriostatic performance of the chronic wound dressing is good, and the wound repair ability is excellent. The dressing is used for treating various chronic wounds caused by cancer radiotherapy, diabetes, ischemia and the like, and induces cleaning and repairing of the wounds.

The invention relates to a natural pharmaceutical composition, a preparation method of the natural pharmaceutical composition and the use of the natural pharmaceutical composition for preparing toxicity-reducing efficacy-improving medicine in cancer radiotherapy and chemotherapy. The natural pharmaceutical composition consists of decocted and concentrated extract of ginger and clove, gingerol, clove ethanol extract and eugenol based on the proportion of 3 to 6: 2 to 5: 3 to 5: 2 to 9, and the composition has extremely good therapeutic effect for vomiting and other side effects caused by cancer radiotherapy and chemotherapy and can simultaneously play the role of inhibiting tumor.

The invention belongs to the medicine, processing and healthcare food technical field of cordyceps sinensis, particularly relating to a preparation method of the cordyceps sinensis extractive concentrated solution got by hirsrtella sinensis or hirsutella hepialid and applications of the cordyceps sinensis extractive concentrated solution in preparation of various preparation forms of medicine or healthcare products for strengthening and regulating immunity; thereby the solution can be applied for treating deficiency in lung and kidney, cancers and for helping strengthening immunity after themotherapy. The preparation of the invention is that the hirsrtella sinensis is fermented to produce cordyceps sinensis which is extracted respectively by ethanol, water and zymohydrolysis and then the extractive is condensed into concentrated solution which is produced into various preparation forms by spray-drying or directly produced into soft capsules after sterilization, and then the finished product is prepared well after packing and inspecting. No additive is added into the finished product which is composed of the extractive concentrated solution by 100 per cent. The various preparations prepared by the extractive concentrated solution of cordyceps sinensis all have multiple functions of restoring the deficiency in lung and kidney, strengthening immunity and enhancing resistance and have the function of regulating and steadying the immunological system of a human body, not only applicable to sub-healthy people for regular health care but also evident in efficacy for people who takes organ transplantation, cancer radiotherapy and chemotherapy, pneumonia, hepatitis, chronic nephritis and valetudinarianism.

A method for evaluation of cancer diagnosis following cancer radiotherapy, comprising: providing a serum sample of a cancer patient prior to the cancer radiotherapy; and measuring a leukemia inhibitory factor concentration in the serum sample. Also provided is a method for potentiation of cancer radiotherapy, comprising: administrating a leukemia inhibitory factor inhibitor or a leukemia inhibitory factor receptor inhibitor to a subject in need of the cancer radiotherapy.

A method for evaluation of cancer diagnosis following cancer radiotherapy, comprising: providing a serum sample of a cancer patient prior to the cancer radiotherapy; and measuring a leukemia inhibitory factor concentration in the serum sample. Also provided is a method for potentiation of cancer radiotherapy, comprising: administrating a leukemia inhibitory factor inhibitor or a leukemia inhibitory factor receptor inhibitor to a subject in need of the cancer radiotherapy.

The present invention relates to a method of treatment and / or prophylaxis of a microbial infection, comprising the step of administering an effective amount of a compound of formula (I), in which X and Y are either the same or different and selected from a heteroatom; is a double or single bond depending on the heteroatoms X and Y; R1 to R5 are either the same or different and selected from hydrogen or a non-deleterious substituent; and R6 and R7 are either the same or different and selected from hydrogen and a non-deleterious substituent or one of R6 and R7 are absent when there is a double bond present, pharmaceutically acceptable salts or derivatives, pro-drugs, tautomers and / or isomers thereof. The present invention also relates to a method for protecting a subject from radiation damage, a method of cancer radiotherapy and use as an antimicrobial or radioprotective agent of the compound of formula (I) defined above. Some of the compounds of formula (I) are novel and are also described in the present invention, together with pharmaceutical or veterinary compositions containing them.

The invention relates to a natural pharmaceutical composition, a preparation method of the natural pharmaceutical composition and the use of the natural pharmaceutical composition for preparing toxicity-reducing efficacy-improving medicine in cancer radiotherapy and chemotherapy. The natural pharmaceutical composition consists of decocted and concentrated extract of ginger and clove, gingerol, clove ethanol extract and eugenol based on the proportion of 3 to 6: 2 to 5: 3 to 5: 2 to 9, and the composition has extremely good therapeutic effect for vomiting and other side effects caused by cancer radiotherapy and chemotherapy and can simultaneously play the role of inhibiting tumor.

The invention provides a use of CX4945 for preparation of a drug having a reversal effect on gastric cancer cisplatin-resistant radiation tolerance, is used in preparation of the gastric cancer cisplatin-resistant radiation tolerance reversal drug, and provides the CX4945 as a gastric cancer cisplatin-resistant radiation tolerance reversal agent applied in clinic; the CX4945 can overcome the gastric cancer cisplatin-resistant cell radiation tolerance, enhances radiosensitivity, reduces the radiotherapy killing dose, alleviates the response of radiotherapy, improves the curative effect of gastric cancer radiotherapy, and provides a better method for treatment of gastric cancer.

The invention relates to an isoquinoline drug, and its preparation method and application. The molecular formula of the drug is C37H40N2O6.2HCl.nH2O, wherein n is 3 or 3.5. With good storage stability, the isoquinoline drug is suitable for application in preparation of medicines promoting proliferation of white blood cells, preventing white blood cell decrease after cancer radiotherapy and chemotherapy, resisting inflammation, resisting tuberculosis, resisting silicosis, resisting tumor, reducing blood pressure, resisting myocardial anoxia and ischemia, resisting arrhythmia, and treating or preventing other diseases.

The invention provides a production method of tissue compensation glue for cancer radiotherapy, the preparation method comprises the following steps: 1, weighing solid paraffin, low-density polyethylene, a styrene-maleic anhydride copolymer and cross-linked povidone according to the mass ratio of 100: 2: 12-14: 3-7; S2, mixing the styrene-maleic anhydride copolymer with the cross-linked povidone,adding 1,4-dioxane for co-boiling, then cooling to 10-20 DEG C, keeping for 30-40 minutes, then adding hydroxylamine hydrochloride and sodium methoxide to react, then adding methylbenzene for co-boiling for 5 hours, filtering, washing filter residue with diethyl ether and water, and carrying out vacuum drying on the filter residue until the filter residue reaches constant weight to obtain a synergist; S3, mixing and injecting the solid paraffin, the low-density polyethylene and the synergist into a mold, and performing molding and demolding to obtain the tissue compensation adhesive for cancerradiotherapy. The production method provided by the invention has the advantages of simple operation and one-time forming, and the produced tissue compensation glue can be applied to cancer radiotherapy and is good in adhesion to skin.

A nutritional supplement containing fish oil and selenium has been identified that potentiates radiotherapy of tumors in a synergistic fashion. Cotherapy with such a supplement and radiotherapy results in substantially improved reductions in tumor volume of animal models relative to radiotherapy alone, and reduces common side effects such as weight loss, inflammation, and damage to the gastrointestinal tract. Such cotherapy was also found to reduce the incidence of metastasis from the primary implantation site, and to modulate expression of genes associated with apoptosis in tumor cells. A formulation for such a supplement that is both well tolerated and palatable is also provided.

The present invention relates to a radiotherapy enhancer that can reduce the radiation dose and adverse drug reactions when used in combination with a cancer radiotherapy. A radiotherapy enhancer comprising (A) tegafur and (B) gimeracil.

The invention relates to a natural pharmaceutical composition, a preparation method thereof and an application of the natural pharmaceutical composition in preparation of attenuated synergistic medicaments in cancer radiotherapy and chemotherapy. The natural pharmaceutical composition is prepared from extract obtained by concentrating tuber pinellia and dried ginger powder, gingerol, tuber pinellia alkaloid and tuber pinellia polysaccharide according to the ratios of (3-8):(2-6):(1-5):(2-7). The composition has an excellent effect on treating emesis and other side effects caused by cancer radiotherapy and chemotherapy, and can simultaneously play a role in inhibiting tumors.