5 results about "Chemotherapy induced" patented technology

The application provides a use of vincristine and lithium carbonate as co-active ingredients in the preparation of a medicament for treating tumors. The vincristine and lithium carbonate as co-active ingredients of the application have a killing effect on various leukemia cells, including human acute lymphoblastic leukemia cell lines, chronic myeloid leukemia cells, acute monocytic leukemia cell lines; in particular, for human acute lymphoblastic leukemia cell lines, compared with single free drugs (lithium carbonate or vincristine), lithium carbonate and vincristine free drug combination, the leukemia cell proliferation can be more effectively inhibited; in addition, the vincristine and lithium carbonate as co-active ingredients of the application can obviously stimulate the generation of granulocyte colony-stimulating factor, and alleviate the neutropenia side effect caused by chemotherapy.

The application relates to the field of medicinal chemistry and discloses a pyrimidine diamine compound and application thereof. The pyrimidine diamine compound is shown as formula I: The pyrimidine diamine compound of the application can be applied to preparing a product for promoting hair growth and / or preventing hair loss, can promote the hair in the resting phase to enter the growth phase, can stimulate hair growth, can inhibit the hair loss caused by a chemotherapy agent, can resist the chemotherapy toxicity and prevent the hair loss caused by chemotherapy, can inhibit androgen, thereby preventing androgen-induced hair loss, can accelerate the natural growth speed of the hair, can increase the growth weight and length of newly-added hair or the remaining hair after hair loss, and the effect is better than that of minoxidil approved by the FDA.

The present invention relates to a pharmaceutical composition for preventing, ameliorating, or treating anorexia and weight loss, comprising a Bupleuri Radix extract. Specifically, the present invention provides a pharmaceutical composition having effects in preventing, ameliorating, or treating anorexia and weight loss, wherein a Bupleuri Radix extract increases ghrilin, which is a hormone that stimulates appetite, and decreases TPH1(I), which is a serotonin synthase. In addition, a health functional food for preventing or ameliorating anorexia and weight loss, comprising a Bupleuri Radix extract, can be developed, and the extract can be effectively used for the treatment and the development of therapeutic agents for anorexia induced by chemotherapy in the future.

The present disclosure relates to a use of Herombopag or a pharmaceutically acceptable salt thereof in treatment of tumor chemotherapy-induced thrombocytopenia. Specifically, the present disclosure relates to a disease treatment method, comprising: administering to a patient Herombopag or a pharmaceutically acceptable salt thereof, which can significantly increase the blood platelet count of a subject.

To provide a composition for the prevention, improvement, or treatment of mucositis induced by radiotherapy, chemotherapy, or a combination thereof, comprising a glucagon-like peptide-2 (GLP-2) derivative and / or a sustained-release conjugate thereof. [Solution] The present invention relates to the prophylactic or therapeutic use of GLP-2 and its sustained-release conjugates against mucositis induced by radiotherapy, chemotherapy, or a combination thereof. The GLP-2, its sustained-release conjugates, or compositions comprising the same of the present invention may be applied to the prevention, treatment, and improvement of mucositis induced by radiotherapy and / or chemotherapy.