15 results about "Biochemical Activity" patented technology

The invention relates to the technical field of biomedical materials, and provides a preparation method and application of cross-linked carboxymethyl cellulose. The preparation method comprises the following steps: S1, dissolving anhydrous calcium chloride in absolute ethyl alcohol, sterilizing and filtering to obtain a sterile calcium chloride solution; s2, adding the dehydrated and purified sodium carboxymethyl cellulose into a sterile calcium chloride solution, and stirring for reaction; s3, after the reaction is finished, suction filtration is performed, filter residues are collected and washed, residual calcium chloride is removed, then vacuum drying is performed, and cross-linked carboxymethyl cellulose is obtained. The cross-linked carboxymethyl cellulose and sodium carboxymethyl cellulose have high consistency in chemical activity, physiological and biochemical activity, biocompatibility and safety risk, but in physical performance, the cross-linked carboxymethyl cellulose is hydrogel fiber, is insoluble in water, can more remarkably maintain the volume of a filling part, and is longer in duration time, so that the cross-linked carboxymethyl cellulose is more stable in filling. And the effects of instant filling and long-acting filling of the microsphere-containing surface filling agent are realized.

This invention relates to a resin-based nano-iron oxide-enhanced microbial preparation, a method for preparing the same, and its applications. In this invention, after mixing resin-based nano-iron oxide, the microbial preparation, and food waste, at room temperature, the resin-based nano-iron oxide enhances the decomposition of food waste by the microbial preparation through multiple actions, including promoting microbial growth, inducing high activity of functional proteases, and accelerating electron transport processes. The alternating aerobic and anaerobic environments allow the microbial preparation to exert its full effect, resulting in high biochemical activity of metabolites. A reaction under room temperature conditions of 3 to 5 hours can achieve a food waste reduction rate of 80% to 99%. This invention is technically simple, consumes little energy, does not cause secondary pollution, and effectively achieves the goals of food waste reduction, resource recovery, and detoxification.

The present invention provides a scalp cooling device, including a covering part for wrapping a patient's scalp and a cooling part disposed within the covering part. This device can wrap around the patient's scalp and provide a cooling effect, causing the blood vessels in the scalp skin to constrict, reducing the blood flow to the scalp hair follicles, thereby reducing the intake of chemotherapeutic drugs by the hair follicles. Additionally, it lowers biochemical activity, thereby reducing the sensitivity of hair follicles to chemotherapy damage, and reduces the metabolic rate of the hair follicles, thus protecting the patient's hair follicles and preventing or mitigating hair loss caused by chemotherapy. Notably, the cooling part includes a gel-like coolant, which contains a moisture moderator and edible propylene glycol that maintains moisture and provides emulsifying and stabilizing effects, thus offering a long-lasting and stable cooling effect, enhancing the device's effectiveness in preventing hair loss.

The invention discloses a platelet aggregation function detection kit. Comprising a sample pool and a biochemical active membrane integrated part, the sample pool is a cavity capable of accommodating citrate anticoagulant whole blood; a sample adding opening is formed in the top of the sample pool; the sample adding opening and the biochemical active membrane integrated part are separated at the top; a biochemical active membrane is flatly spread in the center of the biochemical active membrane integrated part; a membrane pore is formed in the center of the biochemical active membrane; the biochemical active membrane comprises a membrane surface coating; the membrane surface coating is formed by combining collagen and ristomycin; the platelet aggregation state can be more accurately judged according to a biochemical active membrane formed by two platelet inducers, namely collagen and ristomycin; a special structure formed by the capillary tube, the biochemical active membrane integrated piece, the sample pool and the biochemical active membrane can simulate the process from blood flowing out of a blood vessel to coagulation in vitro.

The present disclosure provides a circuitless micro sensing system and a signal detection method. The system includes: a semiconductor photodiode for receiving excitation light and generating an optical signal; a resistor to be measured, which forms a closed loop with the semiconductor photodiode, and the photoluminescence intensity of the semiconductor photodiode is controlled by changing the resistor to be measured. The circuitless micro sensing system can simultaneously achieve three functions of optical energy harvesting, electrical signal amplification, and optical signal transmission, capture real-time biophysical and biochemical activities in an optical manner, without a complex sensing circuit, and exhibits a superlinear relationship with conductance. Using this mechanism, optical monitoring of biophysical signals and biochemical signals can be realized.

The invention discloses biochemical activity of soybean gibberellin 2-site oxidase GmGA2ox17 and application of the soybean gibberellin 2-site oxidase GmGA2ox17 and belongs to the technical field of biology. The technical problem to be solved by the invention is how to prepare GA34. The protein disclosed by the invention is named as GmGA2ox17, and is A1), A2) or A3) as follows: A1) a protein with an amino acid sequence of SEQ ID No.1; a2) a protein which is obtained by substitution and / or deletion and / or addition of amino acid residues on the amino acid sequence as shown in SEQ ID No.1 in the sequence table, has more than 98% of identity with A1) and has the same function as A1); and A3) a fusion protein obtained by connecting a label to the N end or / and C end of A1) or A2). Experiments prove that the GmGA2ox17 can catalyze GA4 to generate GA34, has the effect of gibberellin 2-position oxidase, and can be used for soybean molecule assisted breeding.

The utility model provides a biochemical sludge accelerated high-efficiency sedimentation device. The device comprises a high-efficiency sedimentation tank, the efficient sedimentation tank is sequentially provided with a mixing area, a flocculation area and a pre-sedimentation area, an inclined tube sedimentation area and a sludge concentration area are arranged behind the pre-sedimentation area, and the inclined tube sedimentation area is located above the sludge concentration area; and a biochemical sludge pipe and a sludge return pipe are connected above the mixing area. Biochemical activated sludge is combined with a general efficient sedimentation process, and the sedimentation effect of a general efficient sedimentation tank is enhanced by utilizing the good flocculation, adsorption and sedimentation capacity of the activated sludge.

Provided is a novel phase transition adjusting element, a part of which comprises a multivalent phase transition domain, and the remaining comprises at least two ligands, wherein at least one ligand is covalently connected to the part containing the multivalent phase transition structural domain, the remaining ligands are covalently linked to the part comprising the multivalent phase transition structural domain or to other ligands, and each of the at least two ligands can specifically bind to cell surface molecules corresponding thereto. After binding to cell surface molecules, the phase transition adjusting element can effectively enrich cell surface molecules by means of driving phase separation, and enhance the aggregation of cell surface molecules (such as receptor oligomerization), thereby regulating and controlling various cell physiological and biochemical activities, such as receptor downstream signal transmission, cell endocytosis, etc.

The application relates to the technical field of biomedical materials, and discloses a preparation method and application of cross-linked carboxymethyl cellulose. The preparation method comprises the following steps: S1, dissolving anhydrous calcium chloride in anhydrous ethanol, filtering to obtain a sterile calcium chloride solution; S2, adding dehydrated and purified sodium carboxymethyl cellulose into the sterile calcium chloride solution, and stirring to react; S3, after the reaction is completed, performing suction filtration, collecting filter residues, washing the filter residues to remove residual calcium chloride, and then vacuum drying the filter residues to obtain cross-linked carboxymethyl cellulose. The cross-linked carboxymethyl cellulose and the sodium carboxymethyl cellulose are highly consistent in chemical activity, physiological and biochemical activity, biocompatibility and safety risk, but the cross-linked carboxymethyl cellulose is a hydrogel fiber and is insoluble in water, can more significantly maintain the volume of a filling site, and has a longer duration, so that the effect of instant filling and long-acting filling of a microsphere-containing facial filler is realized.

The present invention relates to an apparatus for decomposing a polymer compound using a biochemically active solvent, including: a tank in which an inlet and an outlet are formed to allow the polymer compound to pass therethrough, and in which the biochemically active solvent is contained; a conveying unit configured to move the polymer compound supplied through the inlet toward the outlet; and a stirring unit configured to flow the polymer compound moved by the operation of the conveying unit in a direction away from the moving direction thereof, thereby stirring the polymer compound and the biochemically active solvent and increasing the number of times and the time of contact of the polymer compound with the biochemically active solvent.

The present application relates to a kind of quick-setting agent for biochemical sludge rapid settlement and its preparation method, application, preparation method includes the following steps: extracting polysaccharide MI in biochemical active sludge as imprint template molecule;Selecting ferrous salt, cobalt nitrate and sodium fluoride are dissolved in water, stirring to form solution A;Selecting imidazole-dicarboxylic acid is dissolved in sodium hydroxide solution, stirring to form solution B;Solution B is added to solution A and reacts, and MOF suspension is obtained;MOF suspension is transferred to the reaction kettle under nitrogen protection, imprint template molecule, crosslinking agent and initiator are added to react, and the reaction mixture is freeze-dried to remove imprint template molecule, and MI-MOF compound with MI vacancy is obtained;MI-MOF compound with MI vacancy is mixed with high molecular polymer, and MI-MOF quick-setting agent is obtained.The quick-setting agent is synergized by MI-MOF compound with MI vacancy and high molecular polymer, and the flocculation of flocculant is greatly improved.

The present application provides a novel phase transition regulating element, which comprises a part containing a multivalent phase transition domain and at least two ligands, wherein at least one ligand is covalently connected to the part containing the multivalent phase transition domain, and the rest of the ligands are covalently connected to the part containing the multivalent phase transition domain or to the other ligands, and each of the at least two ligands can specifically bind to its corresponding cell surface molecule. The phase transition regulating element of the present application can effectively enrich cell surface molecules by driving phase separation after binding to cell surface molecules, enhance the condensation of cell surface molecules (such as receptor oligomerization, etc.), and further regulate a series of cell physiological and biochemical activities, such as receptor downstream signal transmission, cell endocytosis, etc.

The invention relates to the field of soil remediation, and discloses an in-situ synergistic remediation method for atrazine-contaminated soil, arthrobacter uretogenus ATZ-1 and application of the arthrobacter uretogenus ATZ-1. According to the method, animal waste and straw are used as substrates for composting, wine grape skin residues are added in the composting process to serve as humification promoters to improve the humification degree, and reinforced compost is obtained; the reinforced compost and the arthrobacter uretogenus ATZ-1 are jointly applied to the atrazine-polluted soil, and the atrazine-polluted soil is maintained under preset conditions. The enhanced compost as an ecological carrier can improve the survival / colonization and metabolic activity of ATZ-1 in soil, so that atrazine is efficiently removed in a short period, and the improvement of soil biochemical activity (urease and catalase) and the enhancement of the robustness of a microorganism interaction network are considered.

This invention belongs to the field of microencapsulation formulation technology, specifically relating to a biochemical agent and method for regulating the concentration ratio of ultra-high industrial circulating water using self-feedback regulation. It solves the technical problems of existing biochemical agents' inability to sense changes in the localized fouling microenvironment, the spatiotemporal disconnect between efficacy release and fouling, and the susceptibility to structural inactivation and damage. The self-feedback regulated biochemical agent is a core-shell microcapsule with a three-layer structure. From the inside out, it comprises an ultra-high concentration biochemical core in a dehydrated, vitrified dormant state; a flexible stress buffer layer composed of a modified polysiloxane elastomer; and a stimulus-responsive dynamic polymer shell assembled from a polysaccharide backbone grafted with calcium ion shielding groups, a dynamic covalent crosslinking agent, and fouling signal molecule receptors. The stimulus-responsive dynamic polymer shell triggers reversible dissociation and recombination of dynamic covalent bonds based on changes in the concentration of quorum sensing signal molecules, achieving self-feedback release and termination of biochemically active substances, thus completing the autonomous degradation of fouling.

The present invention features novel, diverse, hybrid and engineered recombinase enzymes, and the utility of such proteins with associated recombination factors for carrying out DNA amplification assays. The present invention also features different recombinase ‘systems’ having distinct biochemical activities in DNA amplification assays, and differing requirements for loading factors, single-stranded DNA binding proteins (SSBs), and the quantity of crowding agent employed.