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Tuber pinellia and dried ginger composition, preparation method thereof and application of tuber pinellia and dried ginger composition in preparation of attenuated synergistic medicaments in cancer radiotherapy and chemotherapy

A composition, the technology of Pinellia, applied in the direction of drug combination, digestive system, anti-tumor drugs, etc., to achieve the effect of increasing inhibitory effect, inhibiting tumor, and enhancing inhibitory effect

Inactive Publication Date: 2011-07-27
QINGDAO UNIV
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Problems solved by technology

At present, there is no Chinese patent medicine that can reduce the side effect of vomiting and enhance the effect of anti-cancer radiotherapy and chemotherapy

Method used

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  • Tuber pinellia and dried ginger composition, preparation method thereof and application of tuber pinellia and dried ginger composition in preparation of attenuated synergistic medicaments in cancer radiotherapy and chemotherapy
  • Tuber pinellia and dried ginger composition, preparation method thereof and application of tuber pinellia and dried ginger composition in preparation of attenuated synergistic medicaments in cancer radiotherapy and chemotherapy
  • Tuber pinellia and dried ginger composition, preparation method thereof and application of tuber pinellia and dried ginger composition in preparation of attenuated synergistic medicaments in cancer radiotherapy and chemotherapy

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Experimental program
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Effect test

Embodiment approach

[0042] The first step: preparation of various extracts

[0043] (1) Preparation of Pinellia Ginger Powder Concentrated Extract

[0044] According to the compatibility ratio of 1:1, take pinellia and dried ginger, grind them into coarse powder, add 100 times the amount of slurry water, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, heat and concentrate the filtrate to a small volume, Ultrafiltration membrane filtration, drying under reduced pressure in a vacuum oven at 70°C for 36 hours, is the concentrated extract of Banxia Ganjiang Powder.

[0045] (2) preparation of gingerol

[0046] Dried ginger ginger was cut into thin slices, dried naturally, crushed, sieved, soaked in 6 times the amount of 95% ethanol at room temperature for 72 hours; ultrasonically extracted at 40°C and 40KHz ultrasonic frequency for 15 minutes, centrifuged to obtain the supernatant, and the supernatant The clear liquid was suction filtered under reduced pre...

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Abstract

The invention relates to a natural pharmaceutical composition, a preparation method thereof and an application of the natural pharmaceutical composition in preparation of attenuated synergistic medicaments in cancer radiotherapy and chemotherapy. The natural pharmaceutical composition is prepared from extract obtained by concentrating tuber pinellia and dried ginger powder, gingerol, tuber pinellia alkaloid and tuber pinellia polysaccharide according to the ratios of (3-8):(2-6):(1-5):(2-7). The composition has an excellent effect on treating emesis and other side effects caused by cancer radiotherapy and chemotherapy, and can simultaneously play a role in inhibiting tumors.

Description

technical field [0001] The present invention relates to a natural medicinal composition, more specifically to a natural medicinal composition composed of Pinellia dried ginger powder concentrated extract, gingerol, Pinellia alkaloids and Pinellia polysaccharide, the natural medicinal composition The preparation method of the invention and the use of the natural medicine composition in the preparation of medicines for reducing the side effect of vomiting caused by cancer radiotherapy and chemotherapy and having a synergistic effect on cancer treatment. Background technique [0002] Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive radiotherapy and chemotherapy. Although there is a certain curative effect, most patients will experience side effects to varying degrees after radio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/08A61P35/00A61K31/715A61K31/12
Inventor 石振艳岳旺杨富国刘娜
Owner QINGDAO UNIV
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