Composition of perilla leaf and ginger, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer

A technique of perilla leaves and composition is applied in the field of natural pharmaceutical compositions to achieve the effects of increasing inhibitory effect, reducing vomiting rate and inhibiting tumor

Inactive Publication Date: 2012-05-23
QINGDAO UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no Chinese patent medicine that can reduce the side effect of vomiting and enhance the effect of anti-cancer radiotherapy and chemotherapy

Method used

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  • Composition of perilla leaf and ginger, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer
  • Composition of perilla leaf and ginger, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer
  • Composition of perilla leaf and ginger, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0042] The first step: preparation of various extracts

[0043] (1) Preparation of Perilla Leaf Ginger Decoction Concentrated Extract

[0044] According to the compatibility ratio of 10:3, take perilla leaves and ginger, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 20 minutes, filter with silk cloth, save the filtrate, add 6 times the amount of distilled water to the dregs , soaked, decocted, filtered in the same way, mixed the two filtrates, freeze-dried to obtain a dry extract, pulverized, sieved, and obtained.

[0045] (2) preparation of gingerol

[0046] Cut the ginger into thin slices, dry it naturally, grind it into powder with a high-speed universal pulverizer, pass through a 30-mesh sieve, put the sifted fine powder into a 5000mL large grinding bottle, soak it with 6 times the amount of acetone at room temperature for 72 hours; ℃, ultrasonic extraction at an ultrasonic frequency of 40KHz for ...

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Abstract

The invention relates to a natural pharmaceutical composition, a preparation method thereof and an application thereof in preparing an attenuating synergistic medicament in radiotherapy and chemotherapy of cancer. The natural pharmaceutical composition is composed of concentrated extract of decoctions of perilla leaf and ginger, gingerol, water extract of perilla leaf and perilla leaf oil in proportion of (2-5):(1-3):(2-8):(4-9). The composition provided by the invention has good curative effects on vomit and the like caused by the side effects of radiotherapy and chemotherapy of cancer, and also plays an effect on inhibiting tumor.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of perilla leaf and ginger decoction concentrated extract, gingerol, perilla leaf water extract and perilla leaf oil. The preparation method of the natural medicine composition and the use of the natural medicine composition in the preparation of medicines for reducing the side effect of vomiting caused by cancer radiotherapy and chemotherapy and having a synergistic effect on cancer treatment. Background technique [0002] Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive radiotherapy and chemotherapy. Although there is a certain curative effect, most patients will experience side effects to varying degrees after radiotherapy and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K9/20A61K9/48A61P35/00A61P1/08A61P39/02
Inventor 石振艳岳旺张芳王茂龙
Owner QINGDAO UNIV
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