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Ginger and wild pepper composition and preparation method thereof, and application of ginger and wild pepper composition in preparation of attenuation and synergy medicaments for radiotherapy and chemotherapy of cancers

A composition and a technology for synergistic effect are applied in the ginger and prickly ash composition, its preparation and its use in the preparation of drugs for reducing toxicity and synergism in cancer radiotherapy and chemotherapy, so as to inhibit tumor, reduce vomiting rate, enhance inhibitory effect

Inactive Publication Date: 2012-05-23
QINGDAO UNIV
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

At present, there is no Chinese patent medicine that can reduce the side effect of vomiting and enhance the effect of anti-cancer radiotherapy and chemotherapy

Method used

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  • Ginger and wild pepper composition and preparation method thereof, and application of ginger and wild pepper composition in preparation of attenuation and synergy medicaments for radiotherapy and chemotherapy of cancers
  • Ginger and wild pepper composition and preparation method thereof, and application of ginger and wild pepper composition in preparation of attenuation and synergy medicaments for radiotherapy and chemotherapy of cancers
  • Ginger and wild pepper composition and preparation method thereof, and application of ginger and wild pepper composition in preparation of attenuation and synergy medicaments for radiotherapy and chemotherapy of cancers

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0042] The first step: preparation of various extracts

[0043] (1) Preparation of concentrated extract of ginger and pepper water decoction

[0044] Take ginger and Zanthoxylum bungeanum according to the compatibility ratio of 1:1-4, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 20 minutes, filter with silk cloth, save the filtrate, add 6 times the amount of distilled water to the dregs , soaked, decocted, filtered in the same way, mixed the two filtrates, freeze-dried to obtain a dry extract, pulverized, sieved, and obtained.

[0045] (2) preparation of gingerol

[0046] Cut the ginger into thin slices, dry it naturally, grind it into powder with a high-speed universal pulverizer, pass through a 30-mesh sieve, put the sifted fine powder into a 5000mL large grinding bottle, soak it with 6 times the amount of acetone at room temperature for 72 hours; ℃, ultrasonic extraction at an ultrasonic frequency...

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Abstract

The invention relates to a natural medicinal composition and a preparation method thereof, and application of the natural medicinal composition in the preparation of attenuation and synergy medicaments for radiotherapy and chemotherapy of cancers. The natural medicinal composition comprises the following components in part by weight: 3 to 5 parts of ginger and wild pepper water decoction and concentration extract, 2 to 7 parts of gingerol, 1 to 6 parts of wild pepper water extract and 4 to 7 parts of wild pepper volatile oil. The composition has a good curative effect on side effects such as emesis and the like caused by the radiotherapy and the chemotherapy for the cancers and has the effects of inhibiting tumors at the same time.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of gingerol, Chinese prickly ash water extract and prickly ash volatile oil, the preparation of this natural medicine composition The method and the use of the natural medicine composition in preparing medicines for reducing side effects of vomiting caused by cancer radiotherapy and chemotherapy and synergizing cancer treatment. Background technique [0002] Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive radiotherapy and chemotherapy. Although there is a certain curative effect, most patients will experience side effects to varying degrees after radiotherapy and chemotherapy. The most common side e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K9/20A61K9/48A61P35/00A61P39/02A61P1/08
Inventor 石振艳岳旺张婷婷王园园
Owner QINGDAO UNIV
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