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Ginger and inula flower composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer

A technology of inula flower and composition is applied in the field of ginger and inula flower composition, its preparation and its use in the preparation of drugs for reducing toxicity and synergy in cancer radiotherapy and chemotherapy, so as to reduce the rate of vomiting and enhance inhibition. Effect, good anti-vomiting effect

Inactive Publication Date: 2011-08-31
QINGDAO UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no Chinese patent medicine that can reduce the side effect of vomiting and enhance the effect of anti-cancer radiotherapy and chemotherapy

Method used

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  • Ginger and inula flower composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer
  • Ginger and inula flower composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer
  • Ginger and inula flower composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0042] The first step: preparation of various extracts

[0043] (1) Preparation of Concentrated Extract of Inula Ginger Decoction

[0044] According to the compatibility ratio of 1:1 or 1-4:1, take ginger and inula inula, 10 times the amount of distilled water, soak for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and Add 6 times distilled water to the slag, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C in a vacuum drying oven for 36 hours to obtain a brown yellow powder, which is Concentrated extract of Ginger Inula inula.

[0045] (2) preparation of gingerol

[0046] Cut the ginger into thin slices, dry it naturally, grind it into powder with a high-speed universal pulverizer, pass through a 30-mesh sieve, put the sifted fine powder into a 5000mL large grinding bot...

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Abstract

The invention relates to a natural medicine composition, a preparation method thereof and uses thereof in the preparation of a toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer. The natural medicine composition is prepared from a ginger and inula flower decorated concentrated extract, gingerol, an inula flower chloroform extract and an inula flower ethyl acetate extract at a ratio of (3-7):(2-7):(2-6):(3-5). The composition has an extremely good efficacy for vomiting and other side effects caused by radiotherapy and chemotherapy of cancer, and simultaneously plays a role in suppression of tumors.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composed of concentrated extract of inula officinalis ginger decocted in water, gingerol, chloroform extract of inula inulae and ethyl acetate extract of inula inulae The composition, the preparation method of the natural medicine composition and the use of the natural medicine composition in the preparation of medicines for reducing the side effect of vomiting caused by cancer radiotherapy and chemotherapy and having a synergistic effect on cancer treatment. Background technique [0002] Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive radiotherapy and chemotherapy. Although there is a certain curative effect, most patients will experience side effe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P35/00A61K31/12
Inventor 石振艳岳旺王双燕王茂龙
Owner QINGDAO UNIV
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