Loquat leaf/ginger composition for reducing vomiting due to cancer chemotherapy and enhancing effect of cancer chemotherapy, and preparation method thereof

A technology of loquat leaf and composition, applied in loquat leaf and ginger composition and its preparation field for reducing vomiting caused by cancer chemotherapy and synergizing chemotherapy, to achieve the goal of inhibiting tumor, reducing vomiting rate, and increasing inhibitory effect Effect

Inactive Publication Date: 2012-07-04
QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no Chinese patent medicine that can reduce the side effect of vomiting and enhance the effect of anti-cancer chemotherapy

Method used

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  • Loquat leaf/ginger composition for reducing vomiting due to cancer chemotherapy and enhancing effect of cancer chemotherapy, and preparation method thereof
  • Loquat leaf/ginger composition for reducing vomiting due to cancer chemotherapy and enhancing effect of cancer chemotherapy, and preparation method thereof
  • Loquat leaf/ginger composition for reducing vomiting due to cancer chemotherapy and enhancing effect of cancer chemotherapy, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0042] The first step: preparation of various extracts

[0043] (1) Preparation of Loquat Leaf Ginger Decoction Concentrated Extract

[0044] Take loquat leaves and ginger according to the compatibility ratio of 1:1 or 1-10:1, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 20 minutes, filter with silk cloth, and save the filtrate. Add 6 times distilled water to the dregs of the medicine, soak, decoct, and filter in the same way, mix the two filtrates, freeze-dry to obtain a dry extract, crush, and sieve.

[0045] (2) preparation of gingerol

[0046] Cut the ginger into thin slices, dry it naturally, grind it into powder with a high-speed universal pulverizer, pass through a 30-mesh sieve, put the sifted fine powder into a 5000mL large grinding bottle, soak it with 6 times the amount of acetone at room temperature for 72 hours; ℃, ultrasonic extraction at an ultrasonic frequency of 40KHz for 15 minutes;...

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Abstract

The invention relates to a natural drug composition, a preparation method thereof and use for preparation of drugs for reducing toxicity and enhancing the effect of cancer chemotherapy. The natural drug composition comprises a concentrated water extract of loquat leaf and ginger, gingerol, an ethanol extract of loquat leaf and ursolic acid, at a ratio of (3-8):(1-5):(3-9):(1-3). The composition can significantly relieve vomiting due to cancer chemotherapy as well as inhibit tumor growth.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is composed of loquat leaf ginger decoction concentrated extract, gingerol, loquat leaf ethanol extract and ursolic acid, the natural medicine composition The preparation method of the compound and the use of the natural medicine composition in the preparation of a medicine for reducing the side effect of vomiting caused by cancer chemotherapy and having a synergistic effect on treating cancer. Background technique [0002] Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive chemotherapy. Although there is a certain curative effect, most patients will experience side effects to varying degrees after chemotherapy. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/08A61P35/00A61K31/122A61K31/56
Inventor 石振艳岳旺王双燕倪贝贝
Owner QINGDAO UNIV
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