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Method of extracting proto anthocyanidin by supercritical extraction grape seed oil and resin absorption

A technology of grape seed oil and proanthocyanidins, which is used in solid solvent extraction, pharmaceutical formulations, plant raw materials, etc.

Inactive Publication Date: 2006-01-25
TIANJIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The process of integrating the two technologies to simultaneously obtain two products of grape seed oil and proanthocyanidins has not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0012] Put 1563g of the crushed grape seed raw material into the extraction kettle, the pressure of the extraction kettle is 30MPa, the temperature is 50°C, and after being stabilized for 30 minutes, supercritical CO is continuously fed into the extraction kettle. 2 for extraction, CO 2 The flow rate is 10Kg / h, the extraction time is 3 hours, the temperature of the separating tank is controlled at 20° C., and the pressure is 6 MPa. The product is collected by the receiver, and finally 204 g of grape seed oil is obtained, and the yield of grape seed oil is 13.02%.

[0013] Weigh 100g of grape seed extract and 500mL of prepared 30% ethanol-water solution, mix them into a three-neck flask, stir at 20rpm, heat at 60°C and reflux for about 1h. The filtrate is filtered under reduced pressure, the dregs are recovered, the solvent is added, and the second and third times of heating and reflux are performed for about 0.5 hours respectively. The three extracts were combined and evapora...

example 2

[0015] Put 1587g of crushed grape seed raw materials into the extraction kettle, the pressure of the extraction kettle is 25MPa, the temperature is 45°C, and after being stabilized for 30 minutes, supercritical CO is continuously passed into the extraction kettle. 2 for extraction, CO 2 The flow rate is 10Kg / h, the extraction time is 1 hour, the temperature of the separating tank is controlled at 20°C and the pressure is 5MPa, the product is collected by the receiver, and finally 204g of grape seed oil is obtained, and the yield of grape seed oil is 12.90%.

[0016] Weigh 100g of grape seed extract and mix 500mL of prepared 25% ethanol-water solution into a three-neck flask, stir at 20rpm, heat at 60°C and reflux for about 1h. The filtrate is filtered under reduced pressure, the dregs are recovered, the solvent is added, and the second and third times of heating and reflux are performed for about 0.5 hours respectively. The three extracts were combined and evaporated to 1.2g / ...

example 3

[0018] Put 1576g of crushed grape seed raw material into the extraction kettle, the pressure of the extraction kettle is 35MPa, the temperature is 40°C, and after being stabilized for 30 minutes, the supercritical CO 2 for extraction, CO 2 The flow rate is 10Kg / h, the extraction time is 2 hours, the temperature of the separating tank is controlled at 20° C., and the pressure is 6 MPa. The product is collected by the receiver, and finally 205 g of grape seed oil is obtained, and the yield of grape seed oil is 12.97%.

[0019] Weigh 100g of grape seed extract and 500mL of prepared 35% ethanol-water solution, mix them into a three-neck flask, stir at 20rpm, and heat at 60°C to reflux for about 1h. The filtrate is filtered under reduced pressure, the dregs are recovered, the solvent is added, and the second and third times of heating and reflux are performed for about 0.5 hours respectively. The three extracts were combined and concentrated by evaporation to 1.2 g / ml, and the alc...

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PUM

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Abstract

The invention discloses a process for hypercritical extraction of grape seed oil and resin adsorption abstraction of proanthocyanidin, which comprises, employing hypercritical carbon dioxide to extract grape seed oil from comminuted grape seeds under abstraction pressure of 20-35MPa at 40-50 deg. C, heating degreased grape seeds with 25-35% water solution of ethanol for backflow, charging 50-70% ethanol or isopropanol solution into the concentrated extract liquid, agitating and stewing, decompressing and filtering, thus obtaining proanthocyanidin crude extract liquid, then adsorbing with polystyrene resin, carrying out desorption with desorbent after adsorption saturation, drying the eluent under reduced pressure, finally obtaining refined proanthocyanidin product.

Description

technical field [0001] The invention relates to a method for supercritical extraction of grape seed oil and resin adsorption to extract proanthocyanidins, in particular to the preparation technology of grape seed oil and proanthocyanidins. Background technique [0002] Grape seeds contain about 9-15% grape seed oil, of which linoleic acid content is 45-72%. The linoleic acid contained in grape seed oil has the functions of preventing and treating high blood pressure, arteriosclerosis, and heart disease; it has obvious curative effects on lowering human serum cholesterol and autonomic nervous dysfunction, and has good effects in food, cosmetics, and pharmaceutical industries. application. [0003] Proanthocyanidins (PC) is a general term for a large class of polypeptide phenolic compounds that widely exist in the plant kingdom, and it is formed by condensation of different amounts of catechin or epicatechin. The simplest proanthocyanidins are catechins or epicatechins or di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07D311/62B01D11/02A61K36/87
CPCY02P20/54
Inventor 李淑芬唐韶坤叶春皓姚方耀田松江
Owner TIANJIN UNIV
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