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7 results about "Olfactory system" patented technology

The olfactory system, or sense of smell, is the sensory system used for smelling (olfaction). Olfaction is one of the special senses, that have directly associated specific organs. Most mammals and reptiles have a main olfactory system and an accessory olfactory system. The main olfactory system detects airborne substances, while the accessory system senses fluid-phase stimuli.

Treatment of Memory Loss with Phosphodiesterase Inhibitors

PendingUS20260041690A1Nervous disorderBoron compound active ingredientsPhosphodiesterase inhibitorSmell loss
Smell loss (hyposmia) is a common cognitive deficit perceived clinically as a nasal abnormality but, in reality, it is a deficit of complex biochemical detection and processing of externally generated chemical events. A major mechanism initiating hyposmia involves abnormalities of growth of human olfactory cells through altered growth factor stimulation of stem cell activity. While several growth factors are involved well known signaling substances generate and perpetuate this process; among these substances are cAMP and cGMP. We have hypothesized a role for cAMP in taste and olfaction as a growth factor necessary for stem cell maturation. We have thus measured cAMP and cGMP in parotid saliva of 19 normal subjects and 144 patients with hyposmia to evaluate roles for these signals in cognition. Results indicate that patients secrete significantly less cAMP (0.40+ / −0.03 pmol / mg protein (Mean+ / −SEM); patients; 0.67+ / −0.09, normals, p<0.005) and significantly less cGMP (0.072+ / −0.003, patients; 0.100+ / −0.007, normals, p<0.005) than do normals. While parotid gland secretions relate directly to taste bud growth factors many substances secreted in saliva are similar to those secreted in nasal mucus. The present results indicate aberrant signaling in saliva may serve both as a marker for hyposmia and as an indicator of a mechanism which interferes with olfactory system function.
Owner:CYRANO THERAPEUTICS INC

A polyurethane sponge with mosquito-repellent function and its preparation method

This invention relates to a polyurethane sponge with mosquito-repellent function and its preparation method. The preparation method involves mixing an inflatable polyether polyol, a DEET-modified polyether polyol, a polyether glycol, and ethyl butylacetaminopropionate to obtain a first mixture; mixing a catalyst, an organosilicon surfactant, and a foaming agent to obtain a second mixture; and stirring and mixing the first mixture, the second mixture, and a modified isocyanate, followed by curing. In this preparation method, ethyl butylacetaminopropionate-modified polyether polyol is used as a raw material in the polyurethane reaction, resulting in a graft copolymer that remains permanently within the polyurethane sponge. This creates a barrier within the polyurethane sponge, effectively blocking the emission of odors, paralyzing the olfactory system of mosquitoes, and interfering with their odor perception, thus achieving a mosquito-repellent effect. Furthermore, the tensile strength, elongation, and tear strength all meet relevant standards, demonstrating excellent overall performance.
Owner:FUJIAN GENEROUS SLEEP TECH CO LTD

Electronic nose smell analysis system and method applied to multiple scenes

The application discloses a kind of electronic nose smell analysis system and method applied to multiple scenes, it is characterized in that, including industrial computer, analyzer and sampler composition, wherein, sampler selects pin sampler or multichannel sampler according to detection scene;Pin sampler or multichannel sampler is connected analyzer, analyzer connects industrial computer;External power supply is powered for analyzer and industrial computer, and analyzer is powered for pin sampler or multichannel sampler.The application proposes a kind of machine olfactory system applicable to multiple scenes, with trace sample detection and continuous process volatile detection function, can be applied to chemical or biological laboratory rapid sample detection, or to continuous production process product or by-product monitoring.The machine olfactory system of the application has the advantages of small size, low energy consumption, high constant temperature precision, high degree of automation, fast detection speed and simple use process.
Owner:SHANGHAI ROBOT IND TECH RES INST CO LTD

A biomimetic olfactory sensor chip and a preparation method and application thereof

PendingCN122150349AMaterial electrochemical variablesGate dielectricOlfactory system
The application belongs to the technical field of gas sensing and neuromorphic sensing devices, and more particularly relates to a bionic olfactory sensor chip and a preparation method and application thereof. The bionic olfactory sensor chip comprises a gate electrode, a gate dielectric layer, a two-dimensional alpha-In2Se3 channel layer and a source electrode and a drain electrode connected thereto arranged in sequence. The polarization state of the two-dimensional alpha-In2Se3 channel layer is controlled by the gate electrode voltage, so that when the sensor is exposed to a target gas, the electrical characteristics of the sensor are generated from the relaxation type nonvolatile change associated with the gas adsorption history, thereby realizing the memory of the gas exposure event. The bionic olfactory sensor chip provided by the application can work at room temperature without heating, has the advantages of low power consumption and dynamically adjustable sensing performance, is suitable for environmental monitoring, industrial safety and embodied intelligent mobile terminals, and provides a key device for constructing an artificial olfactory system and a neuromorphic sensing platform.
Owner:HUAZHONG UNIV OF SCI & TECH

Chemosensory modulator system and method for the treatment of chemosensory dysfunction

PCT designated stageWO2025213156A1Head electrodesImplantable neurostimulatorsNervous systemOlfactory disorder
A system and method modify the neural pathways that determine how chemical vapors are perceived and interpreted by the brain. The perception of chemical stimuli is altered by modulating the activity in one or two primary chemosensory pathways: the olfactory and trigeminal systems. By adjusting the relative activity in these pathways, abnormal and unpleasant smell sensations are treated. The system can be used to treat certain parosmias (abnormal smell sensations) and other types of dysosmias by adjusting the ratio of neural activity in the olfactory and trigeminal pathways. For example, patients with impaired olfactory function (decreased olfactory input) often report that "everything smells bad or foul." By adjusting the relative activity in the trigeminal (unpleasant) vs olfactory (pleasant) pathways the unpleasant or foul odor sensation can be treated (e.g., by blocking signals from the trigeminal system or enhancing olfactory stimulation).
Owner:VIRGINIA COMMONWEALTH UNIV

Vehicle-mounted fragrance storage device

ActiveCN223420459UAir-treating devicesGaseous substancesAromatherapyOlfactory system
The utility model belongs to the field of automobile air conditioning, and particularly relates to a vehicle-mounted fragrance storage device which comprises a handle. A heating seat is fixedly connected to the side wall of the top of the handle; the middle part of the side wall of the heating seat is fixedly connected with a connecting rod; a shell is assembled on the side wall of the top of the heating base. A limiting block is in sliding fit with the middle of the side wall of the connecting rod; the limiting block is arranged in the shell; a storage assembly is arranged on the side wall of the top of the shell. By arranging the heating base, the connecting rod, the shell, the limiting block, the first heating groove and the second heating groove, an aromatherapy piece placed in the shell can be heated, so that the aromatherapy piece is rapidly decomposed and eliminates peculiar smells in a vehicle, natural plant essential oil is contained in the aromatherapy piece, the sterilization effect is achieved, heating of the aromatherapy piece is beneficial to purifying air in the vehicle, and the service life of the aromatherapy piece is prolonged. A healthier and fresher driving environment is provided, meanwhile, a driver easily feels tired and sleeps after long-time driving, fragrance released by the vehicle-mounted aromatherapy device capable of being heated can stimulate the olfactory system, and fatigue is delayed.
Owner:HANGZHOU DIANZI UNIVERSITY SHANGYU INSTITUTE OF SCIENCE & ENGINEERING CO LTD

Artificial intelligence olfaction system based on heterogeneous sensor array

PendingCN121186306AMaterial analysisSensor arrayOlfactory system
The invention relates to the technical field of artificial intelligence olfaction, and provides an artificial intelligence olfaction system and method based on a heterogeneous sensor array. In order to solve the problems of incomparability of cross-mechanism response time sequence and quantification and environmental drift interference, the method comprises the following steps: simultaneously acquiring sensing units of at least two mechanisms in the same sampling cavity and under a unified clock, completing denoising, baseline calibration, scale normalization and time alignment in a unified time window, and generating a concentration reference value according to a calibration relationship of quantitative channels such as PID / NDIR; characteristics such as steady state, dynamics and temperature segmentation ratios are extracted based on a standardized time sequence, health degree gating and weighted fusion of noise, baseline drift and saturation signs are combined, a joint model is input, and meanwhile, odor categories, target component concentrations and confidence coefficients are output, so that the method is suitable for complex mixed gas and low-concentration targets. And the cross-mechanism quantitative consistency and robustness are improved.
Owner:杨波