40 results about "Neurologic status" patented technology

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

A method and system for detecting nerve status and relative movement between a nerve and a proximity electrode. The method determines relative movement between a nerve and a proximity electrode by applying multiple signals to a calibration electrode where the energy level of each signal induces a predetermined nerve response. The method also applies multiple signals to the proximity electrode where the energy level of each signal also induces a predetermined nerve response. Based on the variation of the energy level of signals required to induce predetermined nerve responses, the method may detect relative movement between a nerve and a proximity electrode and nerve status.

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

A method and system for detecting nerve status and relative movement between a nerve and a proximity electrode. The method determines relative movement between a nerve and a proximity electrode by applying multiple signals to a calibration electrode where the energy level of each signal induces a predetermined nerve response. The method also applies multiple signals to the proximity electrode where the energy level of each signal also induces a predetermined nerve response. Based on the variation of the energy level of signals required to induce predetermined nerve responses, the method may detect relative movement between a nerve and a proximity electrode and nerve status.

A method and system for detecting nerve status and relative movement between a nerve and a proximity electrode. The method determines relative movement between a nerve and a proximity electrode by applying multiple signals to a calibration electrode where the energy level of each signal induces a predetermined nerve response. The method also applies multiple signals to the proximity electrode where the energy level of each signal also induces a predetermined nerve response. Based on the variation of the energy level of signals required to induce predetermined nerve responses, the method may detect relative movement between a nerve and a proximity electrode and nerve status.

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

A method and apparatus to monitor the neurologic state of a patient undergoing general anesthesia is provided. Previous automated systems to monitor the neurologic state of a patient undergoing general anesthesia involve a significant time delay between the patient's true hypnotic state and the computed indices. The present invention reduces this time delay by using a different analysis technique applied to spontaneous EEG. A wavelet decomposition and statistical analysis of the observed EEG is conducted and compared to reference data to provide a numerical indicator. In addition, this indicator is more consistent with the patient's loss of consciousness indicated by the loss of count event than previous systems.

A neurological control system for modulating activity of any component or structure of some or all of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” This system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state or autonomic state and prevent neurological or metabolic signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals, with sensors configured to sense a particular characteristic indicative of a neurological, psychiatric, or metabolic condition.

Improved methods and devices are provided for detecting and / or predicting the onset of an undesirable physiological event or neural state, such as an epileptic seizure, to facilitate rapid intervention with a treatment therapy such as neurostimulation or drug therapy. The methods and devices involve monitoring the patient's body temperature, preferably by an implanted temperature sensor, to detect a sudden change in a body temperature parameter. The temperature parameter change may comprise an increase or decrease in the patient's body temperature, time rate of change of body temperature, or a difference in a moving average temperature for a first period from that of a second period. When a parameter change is detected that exceeds a threshold, neurostimulation therapy is delivered to a neural structure of the patient.

Improved methods and devices are provided for detecting and / or predicting the onset of an undesirable physiological event or neural state, such as an epileptic seizure, to facilitate rapid intervention with a treatment therapy such as neurostimulation or drug therapy. The methods and devices involve monitoring the patient's body temperature, preferably by an implanted temperature sensor, to detect a change in a body temperature parameter over a first time period. The temperature parameter change may comprise an increase or decrease in the patient's body temperature over a first time period, time rate of change of body temperature over a first time period, a moving average temperature over a first time period, an increase or decrease in body temperature exceeding a target temperature over a first time period, an elevated or reduced body temperature over first time period, or a temperature stability parameter over a first time period. The sampling period at which body temperature measurements are made may be changed manually or depending upon a sensed body parameter, including temperature. When a parameter change is detected that exceeds a threshold, neurostimulation therapy is delivered to a neural structure of the patient.

The neural health or state of a subject is assessed. A recording is obtained of a compound action potential arising in neural tissue of the subject. The recording is processed to determine whether a profile of the recorded compound action potential is anomalous, such as by exhibiting doublets, peak broadening or deformation, or other anomaly. An indication is output regarding the neural state of the subject based on determined anomalies in the recorded compound action potential.

A medical hypnosis device (20) for controlling the administration of a hypnosis experience to a user is described. The device comprises outputting means (24) for outputting a first type of content via one or more media channels to a sensory output device (28a, 28b) for presentation to the user and receiving means (26) for receiving physiological feedback data from a sensor (32a, 32b, 32c) sensing a physiological parameter of the user. The device also comprises processing means (22) for comparing the received physiological feedback data with predetermined physiological data to detect a change in a neurological state of the user. The processing means is arranged, on detection of such a change, to trigger the provision of a second type of content to the user via the outputting means.

A method of extracting features and classifying a neurological state of a subject is provided. The method includes recording brain electrical activity, organizing the recorded data set into digital documents, computing a diffusion geometry on the data set comprising at least a plurality of diffusion coordinates, and classifying the data set into a neurological state based on the metrics provided by the diffusion coordinates.

A method and apparatus for providing an objective assessment of the neurological state of a patient using a field-portable neuro-assessment device is described. The method includes placing an electrode set on the patient's head, acquiring spontaneous brain electrical signals and evoked potential signals from the patient through the electrode set, processing the signals using a handheld base unit, and displaying a result indicating the probability of the patient's neurological signal being normal or abnormal. The neuro-assessment device allows for a rapid, on-site neurological evaluation by an emergency medical technician, triage nurse, or any other medical personnel to identify patients with neurological disorders who may require immediate medical attention.

The present invention provides a closed-loop system for treating neurological disorders, such as epilepsy. In one embodiment the system comprises an input assembly that is adapted to receive one or more signals from a patient that are indicative of a patient's neurological state. The input assembly processes the one or more signals to generate one or more control input signals. An output assembly receives the one or more control input signals from the input assembly and generate a neuromodulation signal that is a function of the patient's neurological state. An electrode array is configured to deliver the neuromodulation signal to a patient's peripheral nerve, such as the vagus nerve.

The invention provides for a wireless and data logging capable bio sensor system worn by individuals that transmits and stores biometric information gathered from multiple and diverse sensors on or near the individual's body. Through these sensors and its transmitters this device can convey and store vast amounts of information pertaining to an individual's physical condition and neurological state as well as the effects of physical activity on the individual's body. This data collection and sensory system could also be applied to biomechanical animal studies. Versions of this invention applied to the medical industry will allow medical specialists and patients to monitor health conditions in real time. This system will log historical biometric data to create an accurate mosaic of physical performances and conditions over a period of time. Logging of individual biometric data will create a unique and key biometric signature for each user.

A method and apparatus to monitor the neurologic state of a patient undergoing general anesthesia is provided. Previous automated systems to monitor the neurologic state of a patient undergoing general anesthesia involve a significant time delay between the patients true hypnotic state and the computed indices. The present invention reduces this time delay by using a different analysis technique applied to spontaneous EEG. A wavelet decomposition and statistical analysis of the observed EEG is conducted and compared to reference data to provide a numerical indicator. In addition, this indicator is more consistent with the patient's loss of consciousness indicated by the loss of count event than previous systems.

A medical hypnosis device (20) for controlling the administration of a hypnosis experience to a user is described. The device comprises a stimulus output module (24) for outputting a first type of content via one or more media channels to a sensory output device (28a, 28b) for presentation to the user and a sensor data receiver (26) for receiving physiological feedback data from a sensor (32a, 32b, 32c) sensing a physiological parameter of the user. The device also comprises a processor (22) for comparing the received physiological feedback data with predetermined physiological data to detect a change in a neurological state of the user. The processor is arranged, on detection of such a change, to trigger the provision of a second type of content to the user via the stimulus output module.

A neurological condition detection unit can include a computer device that is connected to at least two leads that are connectable to a patient for evoking a response from that patient via an electrical current passed through the leads (e.g. a shock) and at plurality of sensors connected to the computer device to sense how the left side and right side of the patient's brain reacts to the evoked event (e.g. the shock). The stroke detection device and / or neurological condition detection unit can be configured to output a warning when one side of the patient's brain is determined to react differently than the opposite side of the patient's brain by at least a pre-selected threshold value. The warning can include an identification of a nearby care facility that may be best suited for providing care to a patient determined to have a neurological condition (e.g. a stroke).

The present invention includes systems and methods for assessing stimulatory effects on a neurologic system. One method may include steps of stimulating the neurologic system, monitoring at least one neurologic state for effects of the stimulation to the neurologic system, gathering multi-dimensional data from the monitoring of the at least one neurological state, and analyzing the multi-dimensional data to determine multi-dimensional interactions between the stimulation and the effects on the at least one neurological state. Various neurologic states are considered to be within the scope of the present invention, including, without limitation, hypnotic, analgesia, relaxation, stress, depression, anxiety, allostasis, immune response, and combinations thereof.

The invention discloses a photo plethysmograph multi-parameter analyzing method of a short autonomic nerve state and relates to a digital signal processing method. The method comprises the following steps of collecting a photo plethysmograph digital signal of the blood volume change of microvessel beds in the skin surface layer of a tested part; conducting the baseline removing treatment on the signal and detecting the peak value point and the valley value point of each beat of the plethysmograph; calculating and obtaining the parameters of interval, range and baseline; sectioning the photo plethysmograph and the three parameters within the time period smaller than one minute; respectively conducting the normalization treatment on the interval, the range and the baseline in the section and obtaining three Poincare plot quantitative indicators; respectively obtaining a first-order differential signal to the interval, the range and the baseline of the photo plethysmograph and calculating the relative coefficient of any two of the three parameters; analyzing the quantitative indicators and conducting the quantitative assessment of the autonomic nerve state through the value change. The photo plethysmograph multi-parameter analyzing method of the short autonomic nerve state can be possibly applied in clinical autonomic nerve state tracking analysis and daily household health monitoring.

Systems and methods for identifying physiological states of a patient are provided. In one aspect, a method includes receiving a time-series of physiological data, and generating a multinomial regression model that includes regression parameters representing signatures of multiple neural states. The method also includes estimating probabilities for each of the neural states by applying the regression model to the time-series of physiological data, and identifying one of a current and future brain state of the patient using the estimated probabilities. The method further includes generating a report indicating a physiological state of the patient.

A method of monitoring relative nerve health and the presence of neuropraxia is described. The methods utilize the integration of a waveform function of an elicited or monitored nerve response to provide an indication of the strength of a detected signal from a nerve and thus the relative health and integrity of the nerve. In some embodiments motor nerve stimulation innervates muscle and an EMG waveform is obtained in response thereto. The integration under the waveform is expressed and an indexed value indicating a percentage of a certain threshold value. Methods set forth provide a more reliable status of a nerve in real-time and allow action to be taken to reduce neuropraxia or prevent permanent nerve damage.