The present invention provides a novel
pyrrolobenzodiazepine derivative compound with significantly reduced side effects such as
toxicity, and a conjugate thereof with its ligand. It also provides a pharmaceutical composition for the prevention or treatment of proliferative disorders, containing the compound or its ligand conjugate as an
active ingredient. Furthermore, the present invention provides a method for preventing or treating proliferative disorders by administering the compound or its ligand conjugate to an individual. [Solution] Specifically, for example, the following compound is shown.
JPEG2026086866000188.jpg35136